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The map label for this gene is mdtH [H]

Identifier: 86608431

GI number: 86608431

Start: 989823

End: 991103

Strand: Reverse

Name: mdtH [H]

Synonym: CYB_0952

Alternate gene names: 86608431

Gene position: 991103-989823 (Counterclockwise)

Preceding gene: 86608432

Following gene: 86608428

Centisome position: 32.53

GC content: 58.7

Gene sequence:

>1281_bases
ATGTGGATCCCTTCTTGGTGGCCGAAGCTCAGTTTTCAGGTTTGGCTGATCTTTATCGGTCGGCTGCTTTCCCAAACTGG
AACCGGCTTTACCTTGTTTTATGCCAGTCTCTTTTTTGTGAATCAGGTGGGGCTGACCGCCACCCAAGTGGGCCTGGGGC
TAGGCATTATGGCTTTTGCCGGGGTGTTTGGCCGCATCCTGGGCGGCTCGATGGCCGATGGAGCTTGGGGGCGCCGTTCC
ACTTTGATCCTCTCTCTGGCTATTTCCACCTTGGGGTCGTTTGGGTTTGCGCTCTCCTATGACTTCTGGAGTTTTGCCCT
GGCCAATATGGCTGCAGGCTTGGGGCAGGGGTTGTACTGGCCGCCTGCGGAAGCGATTGTAGCAGATCTAACCACTCGTG
AGCAGCGCAACGAAGCCTACGCTCTCAACCGTCTGGGGGATAACCTGGGCCTCAGCCTTGGGGTGGCTATGGCCAGCACG
CTGGTGGCTCTGACGGGGGCCTATCGGCTCTTGTTTGTAATCGACGGTGTCACTTTTCTAATCTTTCTGGCAGTACTTTG
GTTTTTTATCCGGGAAACTCGGGCGACTTGTCCGGCAGCAGAGCCTGTGTTGGCAGGTTGGAAAACCGCCCTTAGAGATC
GCTCCCTTTTGGTGTTTGGCCTGTCGAATATCCTGTTCACCACCTATGTGGCCCAGCTCAGCAGCAGCATGCCCCTTTAC
TTCCGCAATGGGGTAGGGATCCCAGAGGTGCAAATCGGCATTTTGTTTGCCTTGCATGGGGCCTTGATCGCTCTGCTGCA
GATGCCGGTGGCCCGTTGGTTGAATCGCCGGACGCGCATCCAAGGGTTGCAGGGATCCGCCCTGATGTGGGGGGTGGGAT
TTCTTTTGGTTTGGCTTAGCGGTCTGGCGGCGGAATTGGGGGCTCCGGCCCCGGCGGTGGCAGTCTTGGCGCTGGCGGTG
CTCTCTTTGGCGTTGGTGAGCTACAACCCCTCTGCCTCTGCTTTGGTGGCGGATTTGGCGCCGGATCACTTGCGGGGGGT
GTATCTGTCGGTCAACTCCCTCTGCTGGGCGGCGGGGTTTGCTCTTGGCCCAATGATTGGGGGGATGGCCTTGGACTTGC
CGCAACCGTGGGCAAGCGGGTTGTGGATCTTTTGGGTGATCACCGTCAGTTGGGTTTGGGGGATCCTCCGCTTTCTGAAC
CGCATTCTGCCCTGCAAGGTGAATAGGGCCGCAGTGCCTCCGGTGATGGAGCCCGCTCCCCTCGGTGACGCAGAACGCTA
G

Upstream 100 bases:

>100_bases
TACTTGTCAGAGCAGGCTCCTTGCCCTGGCCTCAAGGATCGGGATCCCGTAGGCTAGGTAGGCCCTCCCCTGCTGCACTC
AACATCCTGCTGCACTCAAC

Downstream 100 bases:

>100_bases
AGCCCAGGAAAGAAGCAGATTTTGGGATCCCAGTCTTGGCCAACAGCTGGTTAGAGTATGGATGTCGAACAGGAAGGCTA
GTTCTGCTCTTGTACCCTGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MWIPSWWPKLSFQVWLIFIGRLLSQTGTGFTLFYASLFFVNQVGLTATQVGLGLGIMAFAGVFGRILGGSMADGAWGRRS
TLILSLAISTLGSFGFALSYDFWSFALANMAAGLGQGLYWPPAEAIVADLTTREQRNEAYALNRLGDNLGLSLGVAMAST
LVALTGAYRLLFVIDGVTFLIFLAVLWFFIRETRATCPAAEPVLAGWKTALRDRSLLVFGLSNILFTTYVAQLSSSMPLY
FRNGVGIPEVQIGILFALHGALIALLQMPVARWLNRRTRIQGLQGSALMWGVGFLLVWLSGLAAELGAPAPAVAVLALAV
LSLALVSYNPSASALVADLAPDHLRGVYLSVNSLCWAAGFALGPMIGGMALDLPQPWASGLWIFWVITVSWVWGILRFLN
RILPCKVNRAAVPPVMEPAPLGDAER

Sequences:

>Translated_426_residues
MWIPSWWPKLSFQVWLIFIGRLLSQTGTGFTLFYASLFFVNQVGLTATQVGLGLGIMAFAGVFGRILGGSMADGAWGRRS
TLILSLAISTLGSFGFALSYDFWSFALANMAAGLGQGLYWPPAEAIVADLTTREQRNEAYALNRLGDNLGLSLGVAMAST
LVALTGAYRLLFVIDGVTFLIFLAVLWFFIRETRATCPAAEPVLAGWKTALRDRSLLVFGLSNILFTTYVAQLSSSMPLY
FRNGVGIPEVQIGILFALHGALIALLQMPVARWLNRRTRIQGLQGSALMWGVGFLLVWLSGLAAELGAPAPAVAVLALAV
LSLALVSYNPSASALVADLAPDHLRGVYLSVNSLCWAAGFALGPMIGGMALDLPQPWASGLWIFWVITVSWVWGILRFLN
RILPCKVNRAAVPPVMEPAPLGDAER
>Mature_426_residues
MWIPSWWPKLSFQVWLIFIGRLLSQTGTGFTLFYASLFFVNQVGLTATQVGLGLGIMAFAGVFGRILGGSMADGAWGRRS
TLILSLAISTLGSFGFALSYDFWSFALANMAAGLGQGLYWPPAEAIVADLTTREQRNEAYALNRLGDNLGLSLGVAMAST
LVALTGAYRLLFVIDGVTFLIFLAVLWFFIRETRATCPAAEPVLAGWKTALRDRSLLVFGLSNILFTTYVAQLSSSMPLY
FRNGVGIPEVQIGILFALHGALIALLQMPVARWLNRRTRIQGLQGSALMWGVGFLLVWLSGLAAELGAPAPAVAVLALAV
LSLALVSYNPSASALVADLAPDHLRGVYLSVNSLCWAAGFALGPMIGGMALDLPQPWASGLWIFWVITVSWVWGILRFLN
RILPCKVNRAAVPPVMEPAPLGDAER

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081828, Length=319, Percent_Identity=23.8244514106583, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR022855
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45930; Mature: 45930

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWIPSWWPKLSFQVWLIFIGRLLSQTGTGFTLFYASLFFVNQVGLTATQVGLGLGIMAFA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GVFGRILGGSMADGAWGRRSTLILSLAISTLGSFGFALSYDFWSFALANMAAGLGQGLYW
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PPAEAIVADLTTREQRNEAYALNRLGDNLGLSLGVAMASTLVALTGAYRLLFVIDGVTFL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFLAVLWFFIRETRATCPAAEPVLAGWKTALRDRSLLVFGLSNILFTTYVAQLSSSMPLY
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEE
FRNGVGIPEVQIGILFALHGALIALLQMPVARWLNRRTRIQGLQGSALMWGVGFLLVWLS
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GLAAELGAPAPAVAVLALAVLSLALVSYNPSASALVADLAPDHLRGVYLSVNSLCWAAGF
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALGPMIGGMALDLPQPWASGLWIFWVITVSWVWGILRFLNRILPCKVNRAAVPPVMEPAP
HHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LGDAER
CCCCCC
>Mature Secondary Structure
MWIPSWWPKLSFQVWLIFIGRLLSQTGTGFTLFYASLFFVNQVGLTATQVGLGLGIMAFA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GVFGRILGGSMADGAWGRRSTLILSLAISTLGSFGFALSYDFWSFALANMAAGLGQGLYW
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PPAEAIVADLTTREQRNEAYALNRLGDNLGLSLGVAMASTLVALTGAYRLLFVIDGVTFL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFLAVLWFFIRETRATCPAAEPVLAGWKTALRDRSLLVFGLSNILFTTYVAQLSSSMPLY
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEE
FRNGVGIPEVQIGILFALHGALIALLQMPVARWLNRRTRIQGLQGSALMWGVGFLLVWLS
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GLAAELGAPAPAVAVLALAVLSLALVSYNPSASALVADLAPDHLRGVYLSVNSLCWAAGF
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALGPMIGGMALDLPQPWASGLWIFWVITVSWVWGILRFLNRILPCKVNRAAVPPVMEPAP
HHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LGDAER
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA