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The map label for this gene is hup-2 [H]

Identifier: 86608376

GI number: 86608376

Start: 929515

End: 929820

Strand: Direct

Name: hup-2 [H]

Synonym: CYB_0896

Alternate gene names: 86608376

Gene position: 929515-929820 (Clockwise)

Preceding gene: 86608375

Following gene: 86608377

Centisome position: 30.51

GC content: 54.25

Gene sequence:

>306_bases
ATGAACAAGGCAGAACTTGTTGATGCCGTCGCTCATCGCGCCAATGTAACCAAAAAAGAAGCGGAGGCTGTCATTTCGGC
AGCACTGGAGATCATTGTCGAAGAGGTCGCATCCCGCGATGAAAACGGTGAACCCAAGGGGAAGGTGATCCTGGTGGGCT
TCGGCTCCTTTGAGGCTCGCAAGCGCAAAGAGCGGGAAGGTCGCAACCCGAAAACCAACCAAAAGATGGTGATCCCAGAG
AGAATCGTCCCCACTTTTGCGGCGGGCAAGTCATTCCGCGAAGCAGTAGCAGGGGGGAAATCTTAA

Upstream 100 bases:

>100_bases
ACTGAGAACACTCTGGGCCGTGGCCGCTCTGCAACGCCTGAGCGAATCCGCGATCCAGGGAACGCTCTAACTTTATTGCC
TAACTCAAAAGGAGATCAGG

Downstream 100 bases:

>100_bases
TTTCGCCGGGTTGGGACTCGGCTGCTGGGTAAGGCGTGGAGCGGCCTCGACACGGTGGCAATTGGGCTTGGGGAGCAGCA
ATCGCTGGCTGCTCTCCCCA

Product: DNA-binding protein HU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MNKAELVDAVAHRANVTKKEAEAVISAALEIIVEEVASRDENGEPKGKVILVGFGSFEARKRKEREGRNPKTNQKMVIPE
RIVPTFAAGKSFREAVAGGKS

Sequences:

>Translated_101_residues
MNKAELVDAVAHRANVTKKEAEAVISAALEIIVEEVASRDENGEPKGKVILVGFGSFEARKRKEREGRNPKTNQKMVIPE
RIVPTFAAGKSFREAVAGGKS
>Mature_101_residues
MNKAELVDAVAHRANVTKKEAEAVISAALEIIVEEVASRDENGEPKGKVILVGFGSFEARKRKEREGRNPKTNQKMVIPE
RIVPTFAAGKSFREAVAGGKS

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. It is essential for heterocyst differentiation [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=96, Percent_Identity=38.5416666666667, Blast_Score=72, Evalue=6e-15,
Organism=Escherichia coli, GI1786644, Length=96, Percent_Identity=36.4583333333333, Blast_Score=69, Evalue=7e-14,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10961; Mature: 10961

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAELVDAVAHRANVTKKEAEAVISAALEIIVEEVASRDENGEPKGKVILVGFGSFEAR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHH
KRKEREGRNPKTNQKMVIPERIVPTFAAGKSFREAVAGGKS
HHHHHCCCCCCCCCEEECHHHHHHHHHCCHHHHHHHCCCCC
>Mature Secondary Structure
MNKAELVDAVAHRANVTKKEAEAVISAALEIIVEEVASRDENGEPKGKVILVGFGSFEAR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHH
KRKEREGRNPKTNQKMVIPERIVPTFAAGKSFREAVAGGKS
HHHHHCCCCCCCCCEEECHHHHHHHHHCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655556; 7748931; 11759840 [H]