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The map label for this gene is 86608300

Identifier: 86608300

GI number: 86608300

Start: 846925

End: 848778

Strand: Reverse

Name: 86608300

Synonym: CYB_0818

Alternate gene names: NA

Gene position: 848778-846925 (Counterclockwise)

Preceding gene: 86608303

Following gene: 86608299

Centisome position: 27.86

GC content: 60.14

Gene sequence:

>1854_bases
ATGAAATTCAGACGCTGGTTGGGTCTTTGCTGCGCCGGCTTGATGGCCTTGCTGTTGACGGCTTGCGGCAAGGGATCCGC
CCCCTACGACAGCATCGTGGTCAATTTTGTAAACACGGCCACCCCCAGTCAGATTGCTGCTATCGCTAAAGAGTATCATT
TGACGCTCCGCCCCAGCAGCGACAGCGCTTTTGCCCGCCAGGAAGCGATCTATCTGTTTGACGTGGATGCCAACCACCTG
GGATCCACGCGGCGGCTGGTTAAGCGGCTCACCGACGAAGCTTTGATCGAGTATGCTCACCCCAACTATCAATTCCAGGC
GGCTTTCGTGCCCAACGACCGCCTCTATCCCCAGCAATGGAACCTCAGGGCCATCCGCATGCCGGAAGCCTGGGACATCT
CCCAAGGGGAAGGGGTGACGGTAGCCGTGGTGGACACAGGAGTAACCCGAGTTCCCGACCTGGCCCAAACCCAATTTGTT
AAGGGCTATGACTTTGTGGACGACGATGAGGAGCCGGAAGACCTCAACGGCCACGGCACCCATGTGGCGGGAACCATCGC
CCAATCCACCAACAATGTCTTGGGTGTAGCCGGCATTGCCTTCAAGGCCAAGATCATGCCGGTACGGGTGTTGGATGCCA
ATGGCTTTGGATCCCTGTCGGATGTGGTGGAAGGGATCCGCTATGCTGCCGACCACGGGGCTACGATCATCAACCTCAGC
CTGGGTAGCCGCGCTTCTGCCCAACTGATGGAAGAGGCGGTGGCCTATGCCCACAGTAAGGGGGTGACGGTGATCGCAGC
CGCTGGCAACGAAAACTCCAACCAGGTGAGCTACCCGGCCCGCTACCCGCATGTGATCGCTGTCTCGGCCACGGGGCCCA
ACGGGGAGAAAGCCCCCTACTCCAACTATGGGGTGGGGGTGGACATCTCTGCTCCCGGCGGAGCCAAAACGCCTGATCAC
CCCGAGTACGGCATTCTGCAGCAAACCATCAATCGTCGTAACCCCAACGAGCCGGTCTTTGCCTACTTCCAAGGCACCAG
CATGGCCACTCCCCACGTAGCCGGTGTGGCAGCCCTGATCCAGGCTCAGGGCATCAAAGACCCGGACAAGGTGGAAGAAG
TGCTGAAAATGTCGGCTACCCCGGTGCCCGGCGACAAACAGAACTTCTACGGGGCTGGTCGTTTGGATGCAGCCAAGGCG
CTGGCCAGGGCCACAGGGCAACAGGAGGAAAACCCCTTGGTGCTCTGGTTGAAGGACTTCCTGCAGTACCTGAACAACAA
TGGCTACCTCAACCCACGCTTCTGGTTCGATGGTGGCCCGATTGCTCTGGTGCCGAAGCTGCTGATGGTGGTGGGCGGCT
ACATTATCCTGGTGCTGATCCGCTGGTGGCTGGCTCCCAAGCGGCTGCTGCAGACGGTGCCTTTGCTGGCTGGGATGCTT
TTGGGCAGTGCCGGTCTTTTCCCCTTGCAGGGGTTGGCGATTGTCGGTGGCCCCCGTTGGCCCTTCCAATTGGCGGGTAG
CTCCCTGCCGGAGTTGGGCACCGCCTTTGCCCAGACCAATGCCTTGAACCCCCTATTTGCCAGCGTGTTGATCCCAGGCC
TGTTGATGTTGCTGCTCCTGGGCCATCGGCGCTGGCGCTGGGCGGTGATTGGCTTGTGCATCGGCATGGCCTCGCATCTG
CTCTTGTCCGGATCCCTGTTTTATGAGGGGGTGCTATGGCTTGGATCCTCTGCTTGGTTGGGTCGCTCCTTCTTGCTCTT
CAATGGCTTGCTCTGCCTGGGCCTGGCCTACTTGGGAGCGCAAGCGGCTACGGAATCTCAATCCACGGCAACCGGGCTGG
CGCTGAGGCAGTGA

Upstream 100 bases:

>100_bases
CTTTTGGCAATTTTGCCCCCATGCCGGATCTCATCTCGTCAATTGTCAATCCAGAGGGCATACTGGTTGCAACATTTTTT
GGATCCCGAGGGCGTGAATT

Downstream 100 bases:

>100_bases
TGCAAGAGTACAGCGGTACCATCCAGTTCCTGGATATCGAAGGGGGAGTGTGGGTGCTGACGCTGCCTTCCGGCGAGCAC
TATGCCCTTTTCCGTGCCCC

Product: S8A family peptidase

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MKFRRWLGLCCAGLMALLLTACGKGSAPYDSIVVNFVNTATPSQIAAIAKEYHLTLRPSSDSAFARQEAIYLFDVDANHL
GSTRRLVKRLTDEALIEYAHPNYQFQAAFVPNDRLYPQQWNLRAIRMPEAWDISQGEGVTVAVVDTGVTRVPDLAQTQFV
KGYDFVDDDEEPEDLNGHGTHVAGTIAQSTNNVLGVAGIAFKAKIMPVRVLDANGFGSLSDVVEGIRYAADHGATIINLS
LGSRASAQLMEEAVAYAHSKGVTVIAAAGNENSNQVSYPARYPHVIAVSATGPNGEKAPYSNYGVGVDISAPGGAKTPDH
PEYGILQQTINRRNPNEPVFAYFQGTSMATPHVAGVAALIQAQGIKDPDKVEEVLKMSATPVPGDKQNFYGAGRLDAAKA
LARATGQQEENPLVLWLKDFLQYLNNNGYLNPRFWFDGGPIALVPKLLMVVGGYIILVLIRWWLAPKRLLQTVPLLAGML
LGSAGLFPLQGLAIVGGPRWPFQLAGSSLPELGTAFAQTNALNPLFASVLIPGLLMLLLLGHRRWRWAVIGLCIGMASHL
LLSGSLFYEGVLWLGSSAWLGRSFLLFNGLLCLGLAYLGAQAATESQSTATGLALRQ

Sequences:

>Translated_617_residues
MKFRRWLGLCCAGLMALLLTACGKGSAPYDSIVVNFVNTATPSQIAAIAKEYHLTLRPSSDSAFARQEAIYLFDVDANHL
GSTRRLVKRLTDEALIEYAHPNYQFQAAFVPNDRLYPQQWNLRAIRMPEAWDISQGEGVTVAVVDTGVTRVPDLAQTQFV
KGYDFVDDDEEPEDLNGHGTHVAGTIAQSTNNVLGVAGIAFKAKIMPVRVLDANGFGSLSDVVEGIRYAADHGATIINLS
LGSRASAQLMEEAVAYAHSKGVTVIAAAGNENSNQVSYPARYPHVIAVSATGPNGEKAPYSNYGVGVDISAPGGAKTPDH
PEYGILQQTINRRNPNEPVFAYFQGTSMATPHVAGVAALIQAQGIKDPDKVEEVLKMSATPVPGDKQNFYGAGRLDAAKA
LARATGQQEENPLVLWLKDFLQYLNNNGYLNPRFWFDGGPIALVPKLLMVVGGYIILVLIRWWLAPKRLLQTVPLLAGML
LGSAGLFPLQGLAIVGGPRWPFQLAGSSLPELGTAFAQTNALNPLFASVLIPGLLMLLLLGHRRWRWAVIGLCIGMASHL
LLSGSLFYEGVLWLGSSAWLGRSFLLFNGLLCLGLAYLGAQAATESQSTATGLALRQ
>Mature_617_residues
MKFRRWLGLCCAGLMALLLTACGKGSAPYDSIVVNFVNTATPSQIAAIAKEYHLTLRPSSDSAFARQEAIYLFDVDANHL
GSTRRLVKRLTDEALIEYAHPNYQFQAAFVPNDRLYPQQWNLRAIRMPEAWDISQGEGVTVAVVDTGVTRVPDLAQTQFV
KGYDFVDDDEEPEDLNGHGTHVAGTIAQSTNNVLGVAGIAFKAKIMPVRVLDANGFGSLSDVVEGIRYAADHGATIINLS
LGSRASAQLMEEAVAYAHSKGVTVIAAAGNENSNQVSYPARYPHVIAVSATGPNGEKAPYSNYGVGVDISAPGGAKTPDH
PEYGILQQTINRRNPNEPVFAYFQGTSMATPHVAGVAALIQAQGIKDPDKVEEVLKMSATPVPGDKQNFYGAGRLDAAKA
LARATGQQEENPLVLWLKDFLQYLNNNGYLNPRFWFDGGPIALVPKLLMVVGGYIILVLIRWWLAPKRLLQTVPLLAGML
LGSAGLFPLQGLAIVGGPRWPFQLAGSSLPELGTAFAQTNALNPLFASVLIPGLLMLLLLGHRRWRWAVIGLCIGMASHL
LLSGSLFYEGVLWLGSSAWLGRSFLLFNGLLCLGLAYLGAQAATESQSTATGLALRQ

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI76443679, Length=133, Percent_Identity=34.5864661654135, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25141268, Length=182, Percent_Identity=31.3186813186813, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71983555, Length=182, Percent_Identity=31.3186813186813, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324576, Length=341, Percent_Identity=30.791788856305, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6320775, Length=240, Percent_Identity=36.6666666666667, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319893, Length=259, Percent_Identity=31.2741312741313, Blast_Score=94, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 66380; Mature: 66380

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRRWLGLCCAGLMALLLTACGKGSAPYDSIVVNFVNTATPSQIAAIAKEYHLTLRPSS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCC
DSAFARQEAIYLFDVDANHLGSTRRLVKRLTDEALIEYAHPNYQFQAAFVPNDRLYPQQW
CCHHHHCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
NLRAIRMPEAWDISQGEGVTVAVVDTGVTRVPDLAQTQFVKGYDFVDDDEEPEDLNGHGT
CEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
HVAGTIAQSTNNVLGVAGIAFKAKIMPVRVLDANGFGSLSDVVEGIRYAADHGATIINLS
EEEEEHHHCCCCEEEEECEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEE
LGSRASAQLMEEAVAYAHSKGVTVIAAAGNENSNQVSYPARYPHVIAVSATGPNGEKAPY
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCEEEEEEECCCCCCCCCC
SNYGVGVDISAPGGAKTPDHPEYGILQQTINRRNPNEPVFAYFQGTSMATPHVAGVAALI
CCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHH
QAQGIKDPDKVEEVLKMSATPVPGDKQNFYGAGRLDAAKALARATGQQEENPLVLWLKDF
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHH
LQYLNNNGYLNPRFWFDGGPIALVPKLLMVVGGYIILVLIRWWLAPKRLLQTVPLLAGML
HHHHCCCCEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LGSAGLFPLQGLAIVGGPRWPFQLAGSSLPELGTAFAQTNALNPLFASVLIPGLLMLLLL
HCCCCCCCCCCEEEECCCCCCHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GHRRWRWAVIGLCIGMASHLLLSGSLFYEGVLWLGSSAWLGRSFLLFNGLLCLGLAYLGA
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QAATESQSTATGLALRQ
HHHCCCCCHHCCCEECC
>Mature Secondary Structure
MKFRRWLGLCCAGLMALLLTACGKGSAPYDSIVVNFVNTATPSQIAAIAKEYHLTLRPSS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCC
DSAFARQEAIYLFDVDANHLGSTRRLVKRLTDEALIEYAHPNYQFQAAFVPNDRLYPQQW
CCHHHHCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
NLRAIRMPEAWDISQGEGVTVAVVDTGVTRVPDLAQTQFVKGYDFVDDDEEPEDLNGHGT
CEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
HVAGTIAQSTNNVLGVAGIAFKAKIMPVRVLDANGFGSLSDVVEGIRYAADHGATIINLS
EEEEEHHHCCCCEEEEECEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEE
LGSRASAQLMEEAVAYAHSKGVTVIAAAGNENSNQVSYPARYPHVIAVSATGPNGEKAPY
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCEEEEEEECCCCCCCCCC
SNYGVGVDISAPGGAKTPDHPEYGILQQTINRRNPNEPVFAYFQGTSMATPHVAGVAALI
CCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHH
QAQGIKDPDKVEEVLKMSATPVPGDKQNFYGAGRLDAAKALARATGQQEENPLVLWLKDF
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHH
LQYLNNNGYLNPRFWFDGGPIALVPKLLMVVGGYIILVLIRWWLAPKRLLQTVPLLAGML
HHHHCCCCEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LGSAGLFPLQGLAIVGGPRWPFQLAGSSLPELGTAFAQTNALNPLFASVLIPGLLMLLLL
HCCCCCCCCCCEEEECCCCCCHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GHRRWRWAVIGLCIGMASHLLLSGSLFYEGVLWLGSSAWLGRSFLLFNGLLCLGLAYLGA
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QAATESQSTATGLALRQ
HHHCCCCCHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]