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The map label for this gene is ywoG [H]

Identifier: 86608053

GI number: 86608053

Start: 570229

End: 571530

Strand: Direct

Name: ywoG [H]

Synonym: CYB_0561

Alternate gene names: 86608053

Gene position: 570229-571530 (Clockwise)

Preceding gene: 86608051

Following gene: 86608054

Centisome position: 18.72

GC content: 60.29

Gene sequence:

>1302_bases
GTGAGGGTATTCGGGCAGCTGCAGCCGGCACAGCGGCGCAACTTGGGCATTTTGTTTGTGGCTGGGCTGCTCTTTTGGGC
CAGTTTATCCTCGCTGCTGCCCACGTTGCCTCTCTACGTCAGAGATGCCGGTGGCACCAGCCAGCAAGTGGGCTGGGTAA
TGGGGGCCTTTTCGATTGGGTTGCTGGCCTTTCGCCCTGCGTTGGGTCGCCTGGCGGATGGCCACAGCCGGCAGATCGTG
CTGCTTATCGGCATGGGGGTGGTGGGGATGGCCCCCATAGGATACTGGCTCTCCGATTGGATCCCATGGGTAGCGCTGGT
GCGAGCCTTTCATGGGGTTAGCATCGCCGCTTTTGCCACGGCCTATGTGACTTTGGTGGTGGATTTTGCCCCAGAAGAAA
AACGGGGTGAGATCCTGGGCTACATGAGTTTGGTCAATCCGATCGGCGCAGCCATTGGCCCTGCTTTGGGCGGCTTTTTG
CAGGAGTTTGCCGGCTATGGCCCTTCGTTTCTCTTCTCTGCTCTGCTGGGGTTGGTGGGCTTTCTTTGTACCCAACTGGT
TCGAGAACAGCGGCGTGAGCATTGGGGATCCCTGCCGATGGATGGGGCCTTCTGGAGCTTTCTGGGCAGCCCGAAGGTGC
GCTCCCTCGCTTGGGTGATGTTTTTGGTGGGGTTGGCCTTCGGCACCCAGACCACCTTTGTGGCCTTGTTAATCCAAGAA
GCCGGAGCTCCCCTGAATCCAGGTCTTTTTTATACGGCAGTGGCCTTTGCCAGCTTTGGAGTGCGCCTGCTCACCGGTCG
CGCTTCCGATCGCTATGGGCGGGGGCCGTTTATCTCCCTCAGCTTGGTCACCTATGCCCTGGCGATGGGGATCCTGATTG
TTGCCAATAGCAGCGGCGCTTTTCTGGCTGCTGGGGTCGCGGTAGGCTGCGGTTTTGGGACTTTGATCCCTCTCATTTCT
GCCCTCGTGGCCGATCGCTCGGAGCCGGCGGAGCGGGGTCGCCTGTTTAGCTTGGTGATGTGCGGGTTTGATTTGGGCAT
TGGCCTGGCGGGGCCCCTTTTGGGCACCTTAGCAGCGGGATCCGGCTATCGAGCCATGTTTGGCTATGCGGCTCTTCTTT
CCTTGGCTTCCTTGGGTTCTTTTCTCTTCTTCTCCAATGGACGACCGGGGGACTCGCTGCGCTTTGCCTTGGGCCTGGGG
CCGGATAGCCTTTCGGGTTGTCTGGAGGACAGCCGCAACCCGACCTCCTGGAGCCACCGGGTCAGCCCGCTCCCCCGGAG
ACGGGATCCCGTTCATAGATAG

Upstream 100 bases:

>100_bases
ACCTAAATATTTCGGGCTGAGGGATCCGGCGAAGGTGGGCTTATCCTAGGGCGCGGTTCTGGGAGAACGCTTTGAGTTCC
ATTTTGCATAAGGAGTTGGC

Downstream 100 bases:

>100_bases
TCTCATATCTCTATCAGATCCCCCCTGCTCCACACCTGATCCACACCTGAATTGAGACTCAAGCCCTCTGCAGTTTCTAC
AGACAAACCGGCCCATTTCT

Product: drug:H+ antiporter-1 family protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRVFGQLQPAQRRNLGILFVAGLLFWASLSSLLPTLPLYVRDAGGTSQQVGWVMGAFSIGLLAFRPALGRLADGHSRQIV
LLIGMGVVGMAPIGYWLSDWIPWVALVRAFHGVSIAAFATAYVTLVVDFAPEEKRGEILGYMSLVNPIGAAIGPALGGFL
QEFAGYGPSFLFSALLGLVGFLCTQLVREQRREHWGSLPMDGAFWSFLGSPKVRSLAWVMFLVGLAFGTQTTFVALLIQE
AGAPLNPGLFYTAVAFASFGVRLLTGRASDRYGRGPFISLSLVTYALAMGILIVANSSGAFLAAGVAVGCGFGTLIPLIS
ALVADRSEPAERGRLFSLVMCGFDLGIGLAGPLLGTLAAGSGYRAMFGYAALLSLASLGSFLFFSNGRPGDSLRFALGLG
PDSLSGCLEDSRNPTSWSHRVSPLPRRRDPVHR

Sequences:

>Translated_433_residues
MRVFGQLQPAQRRNLGILFVAGLLFWASLSSLLPTLPLYVRDAGGTSQQVGWVMGAFSIGLLAFRPALGRLADGHSRQIV
LLIGMGVVGMAPIGYWLSDWIPWVALVRAFHGVSIAAFATAYVTLVVDFAPEEKRGEILGYMSLVNPIGAAIGPALGGFL
QEFAGYGPSFLFSALLGLVGFLCTQLVREQRREHWGSLPMDGAFWSFLGSPKVRSLAWVMFLVGLAFGTQTTFVALLIQE
AGAPLNPGLFYTAVAFASFGVRLLTGRASDRYGRGPFISLSLVTYALAMGILIVANSSGAFLAAGVAVGCGFGTLIPLIS
ALVADRSEPAERGRLFSLVMCGFDLGIGLAGPLLGTLAAGSGYRAMFGYAALLSLASLGSFLFFSNGRPGDSLRFALGLG
PDSLSGCLEDSRNPTSWSHRVSPLPRRRDPVHR
>Mature_433_residues
MRVFGQLQPAQRRNLGILFVAGLLFWASLSSLLPTLPLYVRDAGGTSQQVGWVMGAFSIGLLAFRPALGRLADGHSRQIV
LLIGMGVVGMAPIGYWLSDWIPWVALVRAFHGVSIAAFATAYVTLVVDFAPEEKRGEILGYMSLVNPIGAAIGPALGGFL
QEFAGYGPSFLFSALLGLVGFLCTQLVREQRREHWGSLPMDGAFWSFLGSPKVRSLAWVMFLVGLAFGTQTTFVALLIQE
AGAPLNPGLFYTAVAFASFGVRLLTGRASDRYGRGPFISLSLVTYALAMGILIVANSSGAFLAAGVAVGCGFGTLIPLIS
ALVADRSEPAERGRLFSLVMCGFDLGIGLAGPLLGTLAAGSGYRAMFGYAALLSLASLGSFLFFSNGRPGDSLRFALGLG
PDSLSGCLEDSRNPTSWSHRVSPLPRRRDPVHR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787291, Length=376, Percent_Identity=28.4574468085106, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45932; Mature: 45932

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]