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The map label for this gene is dmpD [H]

Identifier: 86607723

GI number: 86607723

Start: 233532

End: 234650

Strand: Reverse

Name: dmpD [H]

Synonym: CYB_0224

Alternate gene names: 86607723

Gene position: 234650-233532 (Counterclockwise)

Preceding gene: 86607727

Following gene: 86607722

Centisome position: 7.7

GC content: 59.87

Gene sequence:

>1119_bases
ATGAGCCTATTGTTGTCACCCACTCCTCCCTTGCACAGACTCAACTCCCATCCTTCCCCTTCTGCTCGGGTCAGCGCCAA
TTCCGTCGGCAATCCCGGTTTCTCCTCTGTTGATGCGCCCTCCTCTTCCCCAACGGGTAGCGACAGGGATCCCTTGTCGG
CTTTGCCTCGCTACGGCTACTCCCAAACCTGGCATTGGCGGGGCTGGCCCATCCATTTCACCTACACCCCCAGTCGTGCC
CAAACCCCTGCCGGTGTCGTCAACTTGACGGCAGCTCCGGCCCTTTTAATCCATGGATTTGGAGCGTCAGTGGGTCATTG
GCGCCACAACATTCTCCCTCTGGGATCCCAGCGCTCCGTCTATGCCCTCGACCTGCTGGGATTTGGCAAGAGTGCCAAGC
CGGAGATTGCCTACAGCGTTGATCTGTGGGTGGAGCAGGTACACGAGTTTTGGCAAACTCACATTCAGCAGCCCAGCATC
CTGGTGGGCCATTCCATCGGGGGCTTGGTGGGAGTCATTGCCGCCGCCCGCTATCCCCAAATGGTGAAAGGCTTGTGCTT
GATCAGTTGTGCCGATGGGCCTCACCCCGAAGAATTACCCCCTCCCTGGGATGCTCTGGTGCGAGCCCTCTGCGAAGGGA
TTCTGTCGTTGCTGGGGTGCCCCCTCACTTATCCCCACCTCTTCAACTGGCTGCGACAAACCGAGGTGCTACGAGCTTGG
ATCAAGAATGTCTACAAGCGGGATGAGCAGGTGGATGACGAGCTGGTGCAGATCTTCCAGAGACCGGCCTTTGAGCCGGG
GGCAGCCCACGTGTTTTTGGACGGTCTGAGGGCCATTCTCTGCCGCCGCTTCGACAGCCCCAAACGCCTGCTGCCCACCC
TAAAAATGCCTATCTTGCTACTTTGGGGCCGAGAAGATCCGGCAGTGCCCAGTTTTTTGGCAGACCAATTTAAGCGCTGG
CAACCTGCCCTCACCTTGGTGAAGCTGCCGGGAGTAGGCCACTGCGCCCACGACGAGCTGCCTCACTGGGTCAACACCCT
CATCGGGGAATGGGCGGCCAGTCTGGAGACCTGCCCTGACTTGCCCACCCCCCTTCAGCGGGATCCCCGAGTCGGCTAG

Upstream 100 bases:

>100_bases
GGGGCACAGTCATGCTGGCATGTCCTAAAGAAGAACCGGTAGCAAAGTAGCTTTGGGCGAGCCGAGAAAACCACTAAGAT
TGGTCTAGCCTAAATTGGAG

Downstream 100 bases:

>100_bases
CTCAGCAAGTGATCTGAGCTATTCCCGGCAAGGTGCCACAAGTGAGGGCTATCGGCACAGGGCCCCCCCCAGCTTGGAAC
ACCCCCAAGCCAAATCCCAG

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: HMSH [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSLLLSPTPPLHRLNSHPSPSARVSANSVGNPGFSSVDAPSSSPTGSDRDPLSALPRYGYSQTWHWRGWPIHFTYTPSRA
QTPAGVVNLTAAPALLIHGFGASVGHWRHNILPLGSQRSVYALDLLGFGKSAKPEIAYSVDLWVEQVHEFWQTHIQQPSI
LVGHSIGGLVGVIAAARYPQMVKGLCLISCADGPHPEELPPPWDALVRALCEGILSLLGCPLTYPHLFNWLRQTEVLRAW
IKNVYKRDEQVDDELVQIFQRPAFEPGAAHVFLDGLRAILCRRFDSPKRLLPTLKMPILLLWGREDPAVPSFLADQFKRW
QPALTLVKLPGVGHCAHDELPHWVNTLIGEWAASLETCPDLPTPLQRDPRVG

Sequences:

>Translated_372_residues
MSLLLSPTPPLHRLNSHPSPSARVSANSVGNPGFSSVDAPSSSPTGSDRDPLSALPRYGYSQTWHWRGWPIHFTYTPSRA
QTPAGVVNLTAAPALLIHGFGASVGHWRHNILPLGSQRSVYALDLLGFGKSAKPEIAYSVDLWVEQVHEFWQTHIQQPSI
LVGHSIGGLVGVIAAARYPQMVKGLCLISCADGPHPEELPPPWDALVRALCEGILSLLGCPLTYPHLFNWLRQTEVLRAW
IKNVYKRDEQVDDELVQIFQRPAFEPGAAHVFLDGLRAILCRRFDSPKRLLPTLKMPILLLWGREDPAVPSFLADQFKRW
QPALTLVKLPGVGHCAHDELPHWVNTLIGEWAASLETCPDLPTPLQRDPRVG
>Mature_371_residues
SLLLSPTPPLHRLNSHPSPSARVSANSVGNPGFSSVDAPSSSPTGSDRDPLSALPRYGYSQTWHWRGWPIHFTYTPSRAQ
TPAGVVNLTAAPALLIHGFGASVGHWRHNILPLGSQRSVYALDLLGFGKSAKPEIAYSVDLWVEQVHEFWQTHIQQPSIL
VGHSIGGLVGVIAAARYPQMVKGLCLISCADGPHPEELPPPWDALVRALCEGILSLLGCPLTYPHLFNWLRQTEVLRAWI
KNVYKRDEQVDDELVQIFQRPAFEPGAAHVFLDGLRAILCRRFDSPKRLLPTLKMPILLLWGREDPAVPSFLADQFKRWQ
PALTLVKLPGVGHCAHDELPHWVNTLIGEWAASLETCPDLPTPLQRDPRVG

Specific function: Conversion of 2-hydroxymuconic acid semialdehyde to 2- hydroxypent-2,4-dienoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=290, Percent_Identity=25.8620689655172, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24586385, Length=99, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24586387, Length=99, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24586391, Length=99, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24586389, Length=99, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 41145; Mature: 41013

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLLSPTPPLHRLNSHPSPSARVSANSVGNPGFSSVDAPSSSPTGSDRDPLSALPRYGY
CCCCCCCCCCHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
SQTWHWRGWPIHFTYTPSRAQTPAGVVNLTAAPALLIHGFGASVGHWRHNILPLGSQRSV
CCCCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCE
YALDLLGFGKSAKPEIAYSVDLWVEQVHEFWQTHIQQPSILVGHSIGGLVGVIAAARYPQ
EEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHH
MVKGLCLISCADGPHPEELPPPWDALVRALCEGILSLLGCPLTYPHLFNWLRQTEVLRAW
HHHCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IKNVYKRDEQVDDELVQIFQRPAFEPGAAHVFLDGLRAILCRRFDSPKRLLPTLKMPILL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEE
LWGREDPAVPSFLADQFKRWQPALTLVKLPGVGHCAHDELPHWVNTLIGEWAASLETCPD
EECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCC
LPTPLQRDPRVG
CCCCCCCCCCCC
>Mature Secondary Structure 
SLLLSPTPPLHRLNSHPSPSARVSANSVGNPGFSSVDAPSSSPTGSDRDPLSALPRYGY
CCCCCCCCCHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
SQTWHWRGWPIHFTYTPSRAQTPAGVVNLTAAPALLIHGFGASVGHWRHNILPLGSQRSV
CCCCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCE
YALDLLGFGKSAKPEIAYSVDLWVEQVHEFWQTHIQQPSILVGHSIGGLVGVIAAARYPQ
EEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHH
MVKGLCLISCADGPHPEELPPPWDALVRALCEGILSLLGCPLTYPHLFNWLRQTEVLRAW
HHHCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IKNVYKRDEQVDDELVQIFQRPAFEPGAAHVFLDGLRAILCRRFDSPKRLLPTLKMPILL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEE
LWGREDPAVPSFLADQFKRWQPALTLVKLPGVGHCAHDELPHWVNTLIGEWAASLETCPD
EECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCC
LPTPLQRDPRVG
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]