Click here to switch to the map view.

The map label for this gene is trpD [H]

Identifier: 86607552

GI number: 86607552

Start: 63176

End: 64207

Strand: Reverse

Name: trpD [H]

Synonym: CYB_0050

Alternate gene names: 86607552

Gene position: 64207-63176 (Counterclockwise)

Preceding gene: 86607554

Following gene: 86607550

Centisome position: 2.11

GC content: 63.08

Gene sequence:

>1032_bases
ATGACGGAAACGGCTGACCTTTGGCCACAGCTTTTGGGGCAGTTGCTGGATCGGCAATCTCTCAGCGAAGCCCAAGCTGA
ACAGTTGATGAACGGTTGGCTCCAGAACCAAGTGCCAGATGTGGTGTCGGGGGCGATTCTGGCGGCCCTGCAAGCCAAGG
GTGTGAGCGCCGGTGAACTGGCCGGCATGGCACGAGTGCTACAGCGGGCTTCGCTGGGATCCCCGCTGGACTTGTCTCTC
CTGGTGGATACCTGTGGCACCGGCGGCGATGGGGCCGGCACTTTTAACATTTCCACGGCGGTGGCCTTTGTGGTCAGTGC
AGCCGGGATCCCGGTGGTCAAACATGGCAACCGTTCCGCCTCTGGCAAGGTCGGCTCGGCGGATGTGCTGGAGGCCCTGG
GGGTGAACTTGGGGGCTGAGCCAGAGCGGGTGCGGGCGGCTGTGGCGGAAGTGGGCATCACCTTTTTGTTTGCTCCCCAG
TGGCACCCGGCCATGCGGGCGGTGATCCCCTATCGGCGGGCCCTCAAGGTTCGCACCATTTTCAACCTGTTGGGGCCCTT
GGTCAACCCCCTCTATCCCAACCGCCAGGTGATCGGGGTTTACGCCCAGGAGCTGGTGCCGGTAATGGCAGAGGCCCTGC
GCCTGTTGGGACGGGAAGGGGCCATTGTGTTGCACAGCCGCGAAGGTCTCGACGAGGCCGGTCTGGATCAACCCACCGAT
CTGGGCATCCTGTCCGGTGGGCTGGTACGGACGGAAGTCTTGAACCCTGCAGATTACGAGCTAACCCTGGCACCCACCCA
AGCTCTCAAGGGGGGGGATGTGGCGGAAAATGCCGCCATCCTCACCCAAGTTCTCCAGGGATCCGGGACGCCTGCCCAGC
AGGATGTGGTGGCCTTGAATGCTGCTTTGGCCCTGCAGGTGGCCGGAGTGGCCCCCGATTGGAGAGCCGGGATCGCCCAA
GCTCGCGAGATTCTCGCCAGGGGTGCCGCTTGGGATCGCTTGCAACAGCTGGTTCATTTTCTCAAGGCTTGA

Upstream 100 bases:

>100_bases
ATCAGCATGGCCCGACCTGCACGAGGCAAGTGACCCAGAGGCGGGATACGCTACTAGATACGCTACTATAAGTACCCGCT
GACACCCAGGATCCCGACCC

Downstream 100 bases:

>100_bases
TGCCGGTAGGAGCCCAGGAGAGGGCGACAGGGATCCCACCTGAGCCTAGGGCTAAAACTCCCGCCCTCGCCCAAAGGCCA
GAACTTCATCCACCCCCAAG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTETADLWPQLLGQLLDRQSLSEAQAEQLMNGWLQNQVPDVVSGAILAALQAKGVSAGELAGMARVLQRASLGSPLDLSL
LVDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSASGKVGSADVLEALGVNLGAEPERVRAAVAEVGITFLFAPQ
WHPAMRAVIPYRRALKVRTIFNLLGPLVNPLYPNRQVIGVYAQELVPVMAEALRLLGREGAIVLHSREGLDEAGLDQPTD
LGILSGGLVRTEVLNPADYELTLAPTQALKGGDVAENAAILTQVLQGSGTPAQQDVVALNAALALQVAGVAPDWRAGIAQ
AREILARGAAWDRLQQLVHFLKA

Sequences:

>Translated_343_residues
MTETADLWPQLLGQLLDRQSLSEAQAEQLMNGWLQNQVPDVVSGAILAALQAKGVSAGELAGMARVLQRASLGSPLDLSL
LVDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSASGKVGSADVLEALGVNLGAEPERVRAAVAEVGITFLFAPQ
WHPAMRAVIPYRRALKVRTIFNLLGPLVNPLYPNRQVIGVYAQELVPVMAEALRLLGREGAIVLHSREGLDEAGLDQPTD
LGILSGGLVRTEVLNPADYELTLAPTQALKGGDVAENAAILTQVLQGSGTPAQQDVVALNAALALQVAGVAPDWRAGIAQ
AREILARGAAWDRLQQLVHFLKA
>Mature_342_residues
TETADLWPQLLGQLLDRQSLSEAQAEQLMNGWLQNQVPDVVSGAILAALQAKGVSAGELAGMARVLQRASLGSPLDLSLL
VDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSASGKVGSADVLEALGVNLGAEPERVRAAVAEVGITFLFAPQW
HPAMRAVIPYRRALKVRTIFNLLGPLVNPLYPNRQVIGVYAQELVPVMAEALRLLGREGAIVLHSREGLDEAGLDQPTDL
GILSGGLVRTEVLNPADYELTLAPTQALKGGDVAENAAILTQVLQGSGTPAQQDVVALNAALALQVAGVAPDWRAGIAQA
REILARGAAWDRLQQLVHFLKA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=335, Percent_Identity=40.2985074626866, Blast_Score=215, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6320561, Length=295, Percent_Identity=30.8474576271186, Blast_Score=115, Evalue=9e-27,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 35864; Mature: 35732

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETADLWPQLLGQLLDRQSLSEAQAEQLMNGWLQNQVPDVVSGAILAALQAKGVSAGEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHH
AGMARVLQRASLGSPLDLSLLVDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSA
HHHHHHHHHHCCCCCCCHHHHEECCCCCCCCCCEEHHHHHHHHHHHHCCCCEEECCCCCC
SGKVGSADVLEALGVNLGAEPERVRAAVAEVGITFLFAPQWHPAMRAVIPYRRALKVRTI
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHH
FNLLGPLVNPLYPNRQVIGVYAQELVPVMAEALRLLGREGAIVLHSREGLDEAGLDQPTD
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
LGILSGGLVRTEVLNPADYELTLAPTQALKGGDVAENAAILTQVLQGSGTPAQQDVVALN
CHHHCCCCHHHHCCCCCCCEEEECHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
AALALQVAGVAPDWRAGIAQAREILARGAAWDRLQQLVHFLKA
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TETADLWPQLLGQLLDRQSLSEAQAEQLMNGWLQNQVPDVVSGAILAALQAKGVSAGEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHH
AGMARVLQRASLGSPLDLSLLVDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSA
HHHHHHHHHHCCCCCCCHHHHEECCCCCCCCCCEEHHHHHHHHHHHHCCCCEEECCCCCC
SGKVGSADVLEALGVNLGAEPERVRAAVAEVGITFLFAPQWHPAMRAVIPYRRALKVRTI
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHH
FNLLGPLVNPLYPNRQVIGVYAQELVPVMAEALRLLGREGAIVLHSREGLDEAGLDQPTD
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
LGILSGGLVRTEVLNPADYELTLAPTQALKGGDVAENAAILTQVLQGSGTPAQQDVVALN
CHHHCCCCHHHHCCCCCCCEEEECHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
AALALQVAGVAPDWRAGIAQAREILARGAAWDRLQQLVHFLKA
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA