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The map label for this gene is putR

Identifier: 86361115

GI number: 86361115

Start: 436880

End: 437374

Strand: Direct

Name: putR

Synonym: RHE_PF00385

Alternate gene names: 86361115

Gene position: 436880-437374 (Clockwise)

Preceding gene: 86361113

Following gene: 86361116

Centisome position: 68.0

GC content: 59.19

Gene sequence:

>495_bases
ATGGCCACAGAACCCGACGTCTTTAGTGAATTAGACCAGTTCGACAGAAAGATCCTTGCGGCGCTGGCCGAGGACGGCAG
GCTGTCGATCACCGATCTGGCGGCACGGGTCGGGCTTTCGAAGACGCCGTGCCAGATCCGCTTCAAGCGGCTGATCAGCG
ACGGCTATATCGAAGGCTTCAAGGCCGTCCTCAATCCGGCGAAAATGCAGCTCGACCACATCGCCTTCGTCGAAGTGAAG
CTCTCCGATACCCGTGAGGCGGCGCTGAAAAGCTTCAACGACGCCATTAAGAAGATCAGGGAAGTTGAGGAGTGCCACAT
GATCGCCGGCCGGTTCGACTATCTCCTGAAGATCCGCACCCGCGACATCGGCCGCTACCGCCGCGTGCTGGGCGAGCGCA
TCTCGACGCTGCCCCATGTTGCCAACACCTCGACGAATGTGGCGATGGAGACGATCAAGGAAGGCTGGGACAAATTCGGA
TCGGGCCTTTCATGA

Upstream 100 bases:

>100_bases
TTGCCGACGCATAATCTACCACAGCCACAAATCGCGATCCCACTTGATTTTAGCGGTTTCCAAGCTGTATGAACTTATGA
AATGATCAAAGATAGTTCAA

Downstream 100 bases:

>100_bases
AGGAAGACGGCCGCCGACAGTCCTGCTAAGCCGATATTCGGCGATTGAAGCTGCGTGCGAGGATCAAGATGGACCAAGCC
AATAGCGTCCCCTTATCGGC

Product: proline dehydrogenase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MATEPDVFSELDQFDRKILAALAEDGRLSITDLAARVGLSKTPCQIRFKRLISDGYIEGFKAVLNPAKMQLDHIAFVEVK
LSDTREAALKSFNDAIKKIREVEECHMIAGRFDYLLKIRTRDIGRYRRVLGERISTLPHVANTSTNVAMETIKEGWDKFG
SGLS

Sequences:

>Translated_164_residues
MATEPDVFSELDQFDRKILAALAEDGRLSITDLAARVGLSKTPCQIRFKRLISDGYIEGFKAVLNPAKMQLDHIAFVEVK
LSDTREAALKSFNDAIKKIREVEECHMIAGRFDYLLKIRTRDIGRYRRVLGERISTLPHVANTSTNVAMETIKEGWDKFG
SGLS
>Mature_163_residues
ATEPDVFSELDQFDRKILAALAEDGRLSITDLAARVGLSKTPCQIRFKRLISDGYIEGFKAVLNPAKMQLDHIAFVEVKL
SDTREAALKSFNDAIKKIREVEECHMIAGRFDYLLKIRTRDIGRYRRVLGERISTLPHVANTSTNVAMETIKEGWDKFGS
GLS

Specific function: Transcriptional activator of the putA gene in response to proline [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=44.5205479452055, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=35.6643356643357, Blast_Score=94, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18490; Mature: 18358

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEPDVFSELDQFDRKILAALAEDGRLSITDLAARVGLSKTPCQIRFKRLISDGYIEGF
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KAVLNPAKMQLDHIAFVEVKLSDTREAALKSFNDAIKKIREVEECHMIAGRFDYLLKIRT
HHHHCHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDIGRYRRVLGERISTLPHVANTSTNVAMETIKEGWDKFGSGLS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ATEPDVFSELDQFDRKILAALAEDGRLSITDLAARVGLSKTPCQIRFKRLISDGYIEGF
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KAVLNPAKMQLDHIAFVEVKLSDTREAALKSFNDAIKKIREVEECHMIAGRFDYLLKIRT
HHHHCHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDIGRYRRVLGERISTLPHVANTSTNVAMETIKEGWDKFGSGLS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8606160 [H]