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The map label for this gene is gph [C]

Identifier: 85859370

GI number: 85859370

Start: 1569120

End: 1569800

Strand: Direct

Name: gph [C]

Synonym: SYN_02775

Alternate gene names: 85859370

Gene position: 1569120-1569800 (Clockwise)

Preceding gene: 85859367

Following gene: 85859371

Centisome position: 49.35

GC content: 46.11

Gene sequence:

>681_bases
GTGCGGAAAATCCGCACAGGGGGACTCCGCAGAGATATGAAAGCCGTGGAAATGATGATTTTTGATTTTGATGGAACACT
GGTCAATTCAGGAGACGATCTGGTAAGTTCAGTCAATCATACCTTGAATCGACTCGATTTGCCCGTGCTTCCGAAAGAAA
ACATCATAGGATTTATCGGCGACGGAGTCCAGAAATTGATTGAACGATCTCTGGGAGACGCTTTTCCGGAACATTTCGAA
GAGGCCATGAGCATTTTCACGGCCTATTATACGGAACACATGCTTGATACAACAGATCTCTATCCGGGAGTTAAAGATAT
TCTCGAGCATTTTCGTGACAAGAAAAAAATCATCATAACGAACAAACGATATGCCTTTACGGTTCAGATAACGAACTCAC
TCCATCTGACTCATCATTTTGATGAGATTATCGGCGTGGACAGCAGGACTTACCGTAAGCCGGACAGACGTCTGATTCAA
CCCCTTCTGCGTCAGTATGGCGTTTCTCCTGAAAAGGCCGTGGTCGTAGGAGACGGGATCAATGATGTGCTTCTGGCCAA
AAATGCGGGAATGATCAGTTGCGCCTTTCTCGGAGGTCTGGGGAGCAGGGAGGAGCTTTTATCTTCAAAACCAGATTATG
TCTGCGAAACCCTTCCTGAATTGACGAGACTCTTCTGCTGA

Upstream 100 bases:

>100_bases
TAACATATGTTTAAAAAAAGAGTCAATCTAAAAGGTATCGGGAAGCGAGGGAAGAAAAAGAGCATAAATCCTTGTCATTA
CGCCTTGAGTTAGATATATA

Downstream 100 bases:

>100_bases
AATGCGGAAAAGAGATCCATGCTGGATAAAATCAGACGTACCATTCAAAAATACCATATGCTGAATCCCGGTGAGCATGT
GATTGCGGCTGTTTCGGGAG

Product: phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRKIRTGGLRRDMKAVEMMIFDFDGTLVNSGDDLVSSVNHTLNRLDLPVLPKENIIGFIGDGVQKLIERSLGDAFPEHFE
EAMSIFTAYYTEHMLDTTDLYPGVKDILEHFRDKKKIIITNKRYAFTVQITNSLHLTHHFDEIIGVDSRTYRKPDRRLIQ
PLLRQYGVSPEKAVVVGDGINDVLLAKNAGMISCAFLGGLGSREELLSSKPDYVCETLPELTRLFC

Sequences:

>Translated_226_residues
MRKIRTGGLRRDMKAVEMMIFDFDGTLVNSGDDLVSSVNHTLNRLDLPVLPKENIIGFIGDGVQKLIERSLGDAFPEHFE
EAMSIFTAYYTEHMLDTTDLYPGVKDILEHFRDKKKIIITNKRYAFTVQITNSLHLTHHFDEIIGVDSRTYRKPDRRLIQ
PLLRQYGVSPEKAVVVGDGINDVLLAKNAGMISCAFLGGLGSREELLSSKPDYVCETLPELTRLFC
>Mature_226_residues
MRKIRTGGLRRDMKAVEMMIFDFDGTLVNSGDDLVSSVNHTLNRLDLPVLPKENIIGFIGDGVQKLIERSLGDAFPEHFE
EAMSIFTAYYTEHMLDTTDLYPGVKDILEHFRDKKKIIITNKRYAFTVQITNSLHLTHHFDEIIGVDSRTYRKPDRRLIQ
PLLRQYGVSPEKAVVVGDGINDVLLAKNAGMISCAFLGGLGSREELLSSKPDYVCETLPELTRLFC

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=226, Percent_Identity=30.5309734513274, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25578; Mature: 25578

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIRTGGLRRDMKAVEMMIFDFDGTLVNSGDDLVSSVNHTLNRLDLPVLPKENIIGFIG
CCCCCCCCHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
DGVQKLIERSLGDAFPEHFEEAMSIFTAYYTEHMLDTTDLYPGVKDILEHFRDKKKIIIT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHCCCCEEEEE
NKRYAFTVQITNSLHLTHHFDEIIGVDSRTYRKPDRRLIQPLLRQYGVSPEKAVVVGDGI
CCCEEEEEEEECCEEHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCC
NDVLLAKNAGMISCAFLGGLGSREELLSSKPDYVCETLPELTRLFC
CCEEEECCCCEEEEHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKIRTGGLRRDMKAVEMMIFDFDGTLVNSGDDLVSSVNHTLNRLDLPVLPKENIIGFIG
CCCCCCCCHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
DGVQKLIERSLGDAFPEHFEEAMSIFTAYYTEHMLDTTDLYPGVKDILEHFRDKKKIIIT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHCCCCEEEEE
NKRYAFTVQITNSLHLTHHFDEIIGVDSRTYRKPDRRLIQPLLRQYGVSPEKAVVVGDGI
CCCEEEEEEEECCEEHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCC
NDVLLAKNAGMISCAFLGGLGSREELLSSKPDYVCETLPELTRLFC
CCEEEECCCCEEEEHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA