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The map label for this gene is mat [H]

Identifier: 85858313

GI number: 85858313

Start: 481958

End: 483235

Strand: Direct

Name: mat [H]

Synonym: SYN_00253

Alternate gene names: 85858313

Gene position: 481958-483235 (Clockwise)

Preceding gene: 85858308

Following gene: 85858324

Centisome position: 15.16

GC content: 51.8

Gene sequence:

>1278_bases
TTGCGTCATTGCAGGAAGGGGCGGAGGGGCAGGTTTTTGCACAATTTCTGCTCAAGAACAAAGGAGGGTACGGACATGAT
CCTGGTAGAAACATTAAAAGGAAAATCTGTAACCGAGCATCGGGTTGAAATTGTTGAACGCAAAGGCATCGGTCACCCCG
ATTACATGTGCGATTCCATAATGGAAGCGATTTCCGTCGCCCTGTCACAGGAATATATCCGGGAGTTCGGAACTGTGCTC
CATCATAACATCGATAAGGGGTTGTTGACCGCCGGCAGGGTGGAGAAGAACTTCGGCGGAGGTCAGGTCCTTGAACCCAT
GGAACTGATTATCGGGGACCGGGCTACTCTCCATGTTGCAGGCCGGAAAATCCCGGTTGTCGAGATTGCCGTCGACACTG
CCAAACAATGGATTCGCAGCCATATGCGGTTTATCGACCCCGACAGGCATCTTAAGTGTCGTGTCGTCCTTTCGCCGGGG
TCCGAGGAACTGACGGATATTTTTACCCGGCCCGGAAAAGTCAGGGCTGCGAATGATACCTCGGCGGCAGTGGGATATTA
TCCGCTGAGTCCTGCCGAGAAGGTCGTTCTGAACCTGGAGCGGCAGCTCAATTCCTCTGAATTCAAGAAAATCCATCCTG
AGACAGGCGAAGATATCAAGATCATGGGCTTGCGGAACGGAAAGACGCTGGAGTTAACAGTTGCCATGCCACTGATCGCC
TCTTTTGTCAGCTCTGAAAAGGACTATTTTGAGAGAAAAATGATTATTCAGAAAGAGATGGAGCAAATGCTCGGCGGGCT
GCCTGAATTCAAAGGAATAAATGTCCATTACAACAACCTCGATGAGCGGGGGAGAGGGCTTGGCGGCGTTTATCTGAGCC
TCCTCGGGACATCGGCGGAGGATGCGGATTCAGGTCAGGTCGGACGCGGAAACCGGGTCAACGGACTCATCTCCGTGAAC
AGACCTCTGGGGACAGAGGCTGCCGCGGGGAAGAATCCTGTCAGCCATGTCGGAAAGATATACAACATACTGGCCCATAA
GATCGCCCGGGAAATCTACGAAAATATCGAAGGGATCAAGGAGGTCTACGTCCTGCTTTTAAGCCGTATCGGAACGCCTG
TCGACAGCCCGCAGATGGCAACAGCCCAGGTTCTTCTTGAGCGTGGGCGGGGAATTGATGAAGTTGCAAAAAGGACGGAA
GAAATTTTCGAAAAGGAATTCTCGGAAATCAACGGGTTCTGCGAGGAATTAAGCGCTGGGAAATATTCCGTCTGTTAG

Upstream 100 bases:

>100_bases
ATGAGAAAAAGAAATAGCAATTTGAAAGGGGTTCATTTTAAATAGAAAAAAGAGGTGCGCTTTTCTGACGACAGCAGGCT
GCCCGCTACTTCTCCAGGAT

Downstream 100 bases:

>100_bases
AGTCGTTTTTCTGTTCCTCGTCATTTCCTGAAAACGTCCGTCGCGCCGGGCTCCGGGGATTCCGGGTGGAGAGCGAATTT
TAACTGCTTTTCGATGACTT

Product: S-adenosylmethionine synthetase

Products: NA

Alternate protein names: AdoMet synthase; Methionine adenosyltransferase [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MRHCRKGRRGRFLHNFCSRTKEGTDMILVETLKGKSVTEHRVEIVERKGIGHPDYMCDSIMEAISVALSQEYIREFGTVL
HHNIDKGLLTAGRVEKNFGGGQVLEPMELIIGDRATLHVAGRKIPVVEIAVDTAKQWIRSHMRFIDPDRHLKCRVVLSPG
SEELTDIFTRPGKVRAANDTSAAVGYYPLSPAEKVVLNLERQLNSSEFKKIHPETGEDIKIMGLRNGKTLELTVAMPLIA
SFVSSEKDYFERKMIIQKEMEQMLGGLPEFKGINVHYNNLDERGRGLGGVYLSLLGTSAEDADSGQVGRGNRVNGLISVN
RPLGTEAAAGKNPVSHVGKIYNILAHKIAREIYENIEGIKEVYVLLLSRIGTPVDSPQMATAQVLLERGRGIDEVAKRTE
EIFEKEFSEINGFCEELSAGKYSVC

Sequences:

>Translated_425_residues
MRHCRKGRRGRFLHNFCSRTKEGTDMILVETLKGKSVTEHRVEIVERKGIGHPDYMCDSIMEAISVALSQEYIREFGTVL
HHNIDKGLLTAGRVEKNFGGGQVLEPMELIIGDRATLHVAGRKIPVVEIAVDTAKQWIRSHMRFIDPDRHLKCRVVLSPG
SEELTDIFTRPGKVRAANDTSAAVGYYPLSPAEKVVLNLERQLNSSEFKKIHPETGEDIKIMGLRNGKTLELTVAMPLIA
SFVSSEKDYFERKMIIQKEMEQMLGGLPEFKGINVHYNNLDERGRGLGGVYLSLLGTSAEDADSGQVGRGNRVNGLISVN
RPLGTEAAAGKNPVSHVGKIYNILAHKIAREIYENIEGIKEVYVLLLSRIGTPVDSPQMATAQVLLERGRGIDEVAKRTE
EIFEKEFSEINGFCEELSAGKYSVC
>Mature_425_residues
MRHCRKGRRGRFLHNFCSRTKEGTDMILVETLKGKSVTEHRVEIVERKGIGHPDYMCDSIMEAISVALSQEYIREFGTVL
HHNIDKGLLTAGRVEKNFGGGQVLEPMELIIGDRATLHVAGRKIPVVEIAVDTAKQWIRSHMRFIDPDRHLKCRVVLSPG
SEELTDIFTRPGKVRAANDTSAAVGYYPLSPAEKVVLNLERQLNSSEFKKIHPETGEDIKIMGLRNGKTLELTVAMPLIA
SFVSSEKDYFERKMIIQKEMEQMLGGLPEFKGINVHYNNLDERGRGLGGVYLSLLGTSAEDADSGQVGRGNRVNGLISVN
RPLGTEAAAGKNPVSHVGKIYNILAHKIAREIYENIEGIKEVYVLLLSRIGTPVDSPQMATAQVLLERGRGIDEVAKRTE
EIFEKEFSEINGFCEELSAGKYSVC

Specific function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP [H]

COG id: COG1812

COG function: function code E; Archaeal S-adenosylmethionine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AdoMet synthase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002795
- ProDom:   PD011777 [H]

Pfam domain/function: PF01941 AdoMet_Synthase [H]

EC number: =2.5.1.6 [H]

Molecular weight: Translated: 47285; Mature: 47285

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHCRKGRRGRFLHNFCSRTKEGTDMILVETLKGKSVTEHRVEIVERKGIGHPDYMCDSI
CCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHH
MEAISVALSQEYIREFGTVLHHNIDKGLLTAGRVEKNFGGGQVLEPMELIIGDRATLHVA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCCCCCHHHHHHHHHCCCEEEEEC
GRKIPVVEIAVDTAKQWIRSHMRFIDPDRHLKCRVVLSPGSEELTDIFTRPGKVRAANDT
CCCCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCEEECCCC
SAAVGYYPLSPAEKVVLNLERQLNSSEFKKIHPETGEDIKIMGLRNGKTLELTVAMPLIA
CCEEEEECCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCEEEEEEHHHHHH
SFVSSEKDYFERKMIIQKEMEQMLGGLPEFKGINVHYNNLDERGRGLGGVYLSLLGTSAE
HHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHCCCHHHHHHHHHCCCCC
DADSGQVGRGNRVNGLISVNRPLGTEAAAGKNPVSHVGKIYNILAHKIAREIYENIEGIK
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVYVLLLSRIGTPVDSPQMATAQVLLERGRGIDEVAKRTEEIFEKEFSEINGFCEELSAG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KYSVC
CCCCC
>Mature Secondary Structure
MRHCRKGRRGRFLHNFCSRTKEGTDMILVETLKGKSVTEHRVEIVERKGIGHPDYMCDSI
CCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHH
MEAISVALSQEYIREFGTVLHHNIDKGLLTAGRVEKNFGGGQVLEPMELIIGDRATLHVA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCCCCCHHHHHHHHHCCCEEEEEC
GRKIPVVEIAVDTAKQWIRSHMRFIDPDRHLKCRVVLSPGSEELTDIFTRPGKVRAANDT
CCCCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCEEECCCC
SAAVGYYPLSPAEKVVLNLERQLNSSEFKKIHPETGEDIKIMGLRNGKTLELTVAMPLIA
CCEEEEECCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCEEEEEEHHHHHH
SFVSSEKDYFERKMIIQKEMEQMLGGLPEFKGINVHYNNLDERGRGLGGVYLSLLGTSAE
HHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHCCCHHHHHHHHHCCCCC
DADSGQVGRGNRVNGLISVNRPLGTEAAAGKNPVSHVGKIYNILAHKIAREIYENIEGIK
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVYVLLLSRIGTPVDSPQMATAQVLLERGRGIDEVAKRTEEIFEKEFSEINGFCEELSAG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KYSVC
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]