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The map label for this gene is purQ [H]

Identifier: 85858205

GI number: 85858205

Start: 357959

End: 358831

Strand: Direct

Name: purQ [H]

Synonym: SYN_00522

Alternate gene names: 85858205

Gene position: 357959-358831 (Clockwise)

Preceding gene: 85858204

Following gene: 85858206

Centisome position: 11.26

GC content: 57.04

Gene sequence:

>873_bases
ATGACGGGGTCGCTGAAAGAAAACAAGGAACAGGGGAAGTTAAGAACAATGCCGCAACGGGTAAAATCCATGGTCATTAC
GGGAAACGGGACGAACTGCGAGATGGAGATGGCTCACGCCTGCCGTCTTGCCGGTTCCGATGAAGTGGACATCGTCCATA
TCAGCGACCTGATCAGTGGGGAAAAGCGTCTCGATGATTATCATTTTCTCAATCTGCCCGGAGGGTTTGTCGACGGCGAC
GACCTCGGTTCCGCCAAGGCCAATGCCAACCGCCTGCTGCATGTCCGCATCCGGGGAACGGAAGAGCGGCTTTACGATTC
GCTGCGCCGTTTCATCGCCGATGGCAAACTGATTCTGGGGGTCTGCAACGGTTTCCAGCTCATGGTCAAGCTGGGACTGC
TGCCCGGTTTCGATGGCGACTATGCGACACAGACCGTAACACTGACCTATAATGACTCCGGAAAATTCGAGGATCGCTGG
GTCTATCTGAAACCGGATCCCTCTTCCCCCTGTGTGTTCACCCGGGAGATGGAAGGAATTTATCTACCCGTCCGGCATGG
GGAAGGAAAGCTGGTGCCGCGGGACGAAGGGATCCTGAAGCGGCTGCACGACCAGAGGCAGGTCGTTCTTCAATACAGCG
ATTCATCCTTCCGGGAGGCTGTGATGGCCTATCCGCAGAATCCCAACGGCTCTACAAACGCCATCGCGGGCCTCTGCAAT
GAAACGGGACGTCTTTTCGGTCTGATGCCGCACCCGGAGGCCTATCTGCATGCAACCAACCACCCCCGCTGGACCCGCGA
GAAACTGCCGGAAGAGGGCCAGGGGCTGCAGATCTTCCGCAACGCGGTAAACTTTCTCCGCCGGGAACTATAG

Upstream 100 bases:

>100_bases
AAAAAGTTCAATATTCAATGGGAGAGGACGGGGTTTTCCGCTGGGAAATAGAAAGTAGAACGCTGTGAGACAGGTTGTTT
GATAACCAGACACCGCTCCG

Downstream 100 bases:

>100_bases
TTTGACTTGATCGGGTTCAAATCTTTTCCCCCAGTATCAGGTAGCTGTGTCTGTCTGGAAGTTCAATGCAGGTCGGTTTC
TCCGCAATAGACTCCTTCAA

Product: phosphoribosylformylglycinamidine synthase

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTGSLKENKEQGKLRTMPQRVKSMVITGNGTNCEMEMAHACRLAGSDEVDIVHISDLISGEKRLDDYHFLNLPGGFVDGD
DLGSAKANANRLLHVRIRGTEERLYDSLRRFIADGKLILGVCNGFQLMVKLGLLPGFDGDYATQTVTLTYNDSGKFEDRW
VYLKPDPSSPCVFTREMEGIYLPVRHGEGKLVPRDEGILKRLHDQRQVVLQYSDSSFREAVMAYPQNPNGSTNAIAGLCN
ETGRLFGLMPHPEAYLHATNHPRWTREKLPEEGQGLQIFRNAVNFLRREL

Sequences:

>Translated_290_residues
MTGSLKENKEQGKLRTMPQRVKSMVITGNGTNCEMEMAHACRLAGSDEVDIVHISDLISGEKRLDDYHFLNLPGGFVDGD
DLGSAKANANRLLHVRIRGTEERLYDSLRRFIADGKLILGVCNGFQLMVKLGLLPGFDGDYATQTVTLTYNDSGKFEDRW
VYLKPDPSSPCVFTREMEGIYLPVRHGEGKLVPRDEGILKRLHDQRQVVLQYSDSSFREAVMAYPQNPNGSTNAIAGLCN
ETGRLFGLMPHPEAYLHATNHPRWTREKLPEEGQGLQIFRNAVNFLRREL
>Mature_289_residues
TGSLKENKEQGKLRTMPQRVKSMVITGNGTNCEMEMAHACRLAGSDEVDIVHISDLISGEKRLDDYHFLNLPGGFVDGDD
LGSAKANANRLLHVRIRGTEERLYDSLRRFIADGKLILGVCNGFQLMVKLGLLPGFDGDYATQTVTLTYNDSGKFEDRWV
YLKPDPSSPCVFTREMEGIYLPVRHGEGKLVPRDEGILKRLHDQRQVVLQYSDSSFREAVMAYPQNPNGSTNAIAGLCNE
TGRLFGLMPHPEAYLHATNHPRWTREKLPEEGQGLQIFRNAVNFLRREL

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=281, Percent_Identity=33.0960854092527, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI48994899, Length=267, Percent_Identity=36.7041198501873, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17553022, Length=276, Percent_Identity=28.2608695652174, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321498, Length=282, Percent_Identity=31.2056737588652, Blast_Score=106, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24582111, Length=245, Percent_Identity=38.7755102040816, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24582109, Length=245, Percent_Identity=38.7755102040816, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI17137292, Length=245, Percent_Identity=38.7755102040816, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 32637; Mature: 32505

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSLKENKEQGKLRTMPQRVKSMVITGNGTNCEMEMAHACRLAGSDEVDIVHISDLISG
CCCCCCCCHHCCHHHHHHHHHHEEEEECCCCCCEEHHHHHHHCCCCCCEEEEEHHHHHCC
EKRLDDYHFLNLPGGFVDGDDLGSAKANANRLLHVRIRGTEERLYDSLRRFIADGKLILG
HHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCEEEE
VCNGFQLMVKLGLLPGFDGDYATQTVTLTYNDSGKFEDRWVYLKPDPSSPCVFTREMEGI
ECCHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCEEEEECCCCE
YLPVRHGEGKLVPRDEGILKRLHDQRQVVLQYSDSSFREAVMAYPQNPNGSTNAIAGLCN
EEEEECCCCCCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHC
ETGRLFGLMPHPEAYLHATNHPRWTREKLPEEGQGLQIFRNAVNFLRREL
CCCCEEEECCCCHHEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGSLKENKEQGKLRTMPQRVKSMVITGNGTNCEMEMAHACRLAGSDEVDIVHISDLISG
CCCCCCCHHCCHHHHHHHHHHEEEEECCCCCCEEHHHHHHHCCCCCCEEEEEHHHHHCC
EKRLDDYHFLNLPGGFVDGDDLGSAKANANRLLHVRIRGTEERLYDSLRRFIADGKLILG
HHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCEEEE
VCNGFQLMVKLGLLPGFDGDYATQTVTLTYNDSGKFEDRWVYLKPDPSSPCVFTREMEGI
ECCHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCEEEEECCCCE
YLPVRHGEGKLVPRDEGILKRLHDQRQVVLQYSDSSFREAVMAYPQNPNGSTNAIAGLCN
EEEEECCCCCCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHC
ETGRLFGLMPHPEAYLHATNHPRWTREKLPEEGQGLQIFRNAVNFLRREL
CCCCEEEECCCCHHEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA