Click here to switch to the map view.

The map label for this gene is kynB

Identifier: 85375656

GI number: 85375656

Start: 2840881

End: 2841531

Strand: Direct

Name: kynB

Synonym: ELI_14145

Alternate gene names: 85375656

Gene position: 2840881-2841531 (Clockwise)

Preceding gene: 85375655

Following gene: 85375657

Centisome position: 93.07

GC content: 63.9

Gene sequence:

>651_bases
ATGAGCAGCTGGAAATCGCAACGGCGCATCTGGGATATTTCGCAGACGCTGCGCCCCGGTCTTCCGATATGGCCCGGCGA
TACCGAGTTCGGGTTCGAGCGGACGTGGCGAATGGACGAAGGCTCGCCGGTCAATGTCGGCAGGATGACCATGAGCACGC
ATTCGGGGACGCACGGCGATGCCCCACTGCATTATGCCGAGGACGGGCTTGACGCGGCTAGCATGGAGCTCGACTCCTAT
ATCGGCGAATGCCTGGTGGTCGATGCACGCGGCGTGAGCGGCGAGATCGACGTCGCCGACCTGCCGCATATCGAAAGCGC
TGACCGGGTGCTGTTCCGCCAGTGGGATTCCTTTCCGCACGACGAATGGCGCAGCGACTGGCTGCCGATCGCGGCGGAGA
CGGTGGAGTGGCTGGCACTCCAGGGCGTCAAGCTGATCGGCACCGATGCGCCTTCGGTCGATCCGCAGGAGTCCAAGACC
ATGAGCGCGCACAAGGCAGTGCTGAAACACGACATGCGCATCCTCGAAGGGCTGGTGCTCGATGACGTGCCGGAGGGACG
GTATGAGCTGCTTGCGCTGCCGCTCAAGATTGTCGACGGCGATGCCGGGCTGTGCCGGGCGATCCTGCGGGAGTTGCCCG
ATGCTGGATAA

Upstream 100 bases:

>100_bases
ACGGGCGGCACCAAGGGTGTGCCGTATCTCGAAGGCGTGCTTAAACAGGCGTTCTTCCCCGAGCTGCTGAGCGTGAGGAC
GGCCATATGAGGGTTGGGAT

Downstream 100 bases:

>100_bases
AGCGCGCGAACTCGATGCGGCGGACGAGCTGGCGCATTTTCGCGACCGCTTCGAAATTCCGGAAGGCGTAATCTATCTCG
ATGGCAATTCCCTCGGCGCG

Product: putative cyclase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSSWKSQRRIWDISQTLRPGLPIWPGDTEFGFERTWRMDEGSPVNVGRMTMSTHSGTHGDAPLHYAEDGLDAASMELDSY
IGECLVVDARGVSGEIDVADLPHIESADRVLFRQWDSFPHDEWRSDWLPIAAETVEWLALQGVKLIGTDAPSVDPQESKT
MSAHKAVLKHDMRILEGLVLDDVPEGRYELLALPLKIVDGDAGLCRAILRELPDAG

Sequences:

>Translated_216_residues
MSSWKSQRRIWDISQTLRPGLPIWPGDTEFGFERTWRMDEGSPVNVGRMTMSTHSGTHGDAPLHYAEDGLDAASMELDSY
IGECLVVDARGVSGEIDVADLPHIESADRVLFRQWDSFPHDEWRSDWLPIAAETVEWLALQGVKLIGTDAPSVDPQESKT
MSAHKAVLKHDMRILEGLVLDDVPEGRYELLALPLKIVDGDAGLCRAILRELPDAG
>Mature_215_residues
SSWKSQRRIWDISQTLRPGLPIWPGDTEFGFERTWRMDEGSPVNVGRMTMSTHSGTHGDAPLHYAEDGLDAASMELDSYI
GECLVVDARGVSGEIDVADLPHIESADRVLFRQWDSFPHDEWRSDWLPIAAETVEWLALQGVKLIGTDAPSVDPQESKTM
SAHKAVLKHDMRILEGLVLDDVPEGRYELLALPLKIVDGDAGLCRAILRELPDAG

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KYNB_ERYLH (Q2N5X0)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_459718.1
- ProteinModelPortal:   Q2N5X0
- STRING:   Q2N5X0
- GeneID:   3871639
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_14145
- NMPDR:   fig|314225.3.peg.189
- eggNOG:   COG1878
- HOGENOM:   HBG686791
- OMA:   ITAKAME
- BioCyc:   ELIT314225:ELI_14145-MONOMER
- InterPro:   IPR017484
- InterPro:   IPR007325
- TIGRFAMs:   TIGR03035

Pfam domain/function: PF04199 Cyclase

EC number: =3.5.1.9

Molecular weight: Translated: 24015; Mature: 23884

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSWKSQRRIWDISQTLRPGLPIWPGDTEFGFERTWRMDEGSPVNVGRMTMSTHSGTHGD
CCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCC
APLHYAEDGLDAASMELDSYIGECLVVDARGVSGEIDVADLPHIESADRVLFRQWDSFPH
CCCEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
DEWRSDWLPIAAETVEWLALQGVKLIGTDAPSVDPQESKTMSAHKAVLKHDMRILEGLVL
HHHHCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DDVPEGRYELLALPLKIVDGDAGLCRAILRELPDAG
CCCCCCCEEEEEEEEEEECCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSWKSQRRIWDISQTLRPGLPIWPGDTEFGFERTWRMDEGSPVNVGRMTMSTHSGTHGD
CCCHHHHHHCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCC
APLHYAEDGLDAASMELDSYIGECLVVDARGVSGEIDVADLPHIESADRVLFRQWDSFPH
CCCEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
DEWRSDWLPIAAETVEWLALQGVKLIGTDAPSVDPQESKTMSAHKAVLKHDMRILEGLVL
HHHHCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DDVPEGRYELLALPLKIVDGDAGLCRAILRELPDAG
CCCCCCCEEEEEEEEEEECCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA