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The map label for this gene is cirA [H]

Identifier: 85375602

GI number: 85375602

Start: 2795245

End: 2797656

Strand: Direct

Name: cirA [H]

Synonym: ELI_13875

Alternate gene names: 85375602

Gene position: 2795245-2797656 (Clockwise)

Preceding gene: 85375601

Following gene: 85375606

Centisome position: 91.58

GC content: 63.56

Gene sequence:

>2412_bases
ATGCGCATTTCCGAAAGCCTTGCGGGATTCCGCGTCCGTTCCGCCCTTCTCGCCGGGTGTGCCTTCGCGCTCGGTGCCAC
GCCGGCCCTTGCGCAGGATAGCGATGAGGACACCGCTTCCAGTGCGCCGCCGCGCGGCAATGTCATCGTGGTGACCGCGA
CCAAGCGCGACCAGACGATCCAGGACATTCCCTTCTCGATCAACGCCCAGACGCAGGAAGACATCCAGCGATCGGGTTCG
GTGACGCTGGAAGACCTGTCGCGCAATGTCGCCGGTCTTACCATCCAGAACCTCGGCCCGGGCCAGAGCCAGGTCGCCGT
GCGCGGTGTTTCCGCCGGCCAGGTCGTGCGCGACCAGCCGGGCGTGAAGGAACAGGTGGGCGTTTATCTCGATGAATCGG
TGATTTCGCTCTCGCTGTTTACGCCCGATCTCGACCTGTTCGACCTCAACCGCGTCGAGACGCTGCGCGGCCCGCAGGGT
ACGCTGTTCGGTTCCGGTTCGGTGGGCGGTACCATCCGCTATATCACCAACCAGCCGACCCCGGGCATCGTCGAAGGCAC
CGTGGAGGCGAACTTCAACGTCCTCGAAAGCGGCGATATCGGCGCGCACCTGAAGGGCGCGGTCAACGTTCCGCTGCTGG
GTGACACGATCACCGCCCGCGCTGTGGGCTACTATACCGAATATGCCGGCTTCATCGACGCGCTCGGCCCGGGAGGCGGC
GAAGACATCAATGACGGTCGTCGCTACGGCGGCCGCGTCGCAGTACGGGTCGATACCGGCGAGGGCGTGAGCTTTACGCC
GCGCATCCTCTACCAGAAGGTCGAGGCCGACGGCTTCAACCGGCAGGAGATCTTCAACCTCTTCGCCAATCCGTTCACGA
CTACCCGGCCCCCGGTCCAACTGGGCGAACGCGAGCAATATCTGCGCCTGCAGGAAGCGTTCGAGGACGAAACCTTCCTG
TTCGACATCGTCGCCGAAGCCGAACTGGGTCCGGTCACGCTGACCTCCGTCAGCACCTATATCAACCGCGACATCTTGGT
CAGCCGCGATGCCAGCGCGTTGACCGGCTCGGTCTCGGTCGATCTCGGCTATCCGCCTGTGGCGGTGCTGCTGCCGTCGA
ACCTTCGCGATACGACCGATCTCGAAACGGTCACGCAGGAAGTGCGGCTCGCCTCCAACACCGACGGCCGCTTCCAGTGG
CTGGTCGGCGCGTTCTATTCGGAAGTCGATCGCGTTTACACGCAGCGCCTGCCGACTCCGGGCTATGCGGCGTTTACGGA
CGCCACACTGGGTGCAGGCACTTCGGCGGCGGTGGCCAACGGCTTCCCGAACCTCGATTCTCCGTTCAACTCGGACCTGC
CCTACGACATCAGCCAAATCGCGGTTTTCGGCGAGGCTAGCTTCGAAGTGACCGACGCGCTGACCATCACCGCGGGCGGG
CGCTACTACGATTTCGAGGAAACCCGCACGATCACCACCGGCGGCCTGTTCGCCAATGGCGATAGCGGCGTGGTCGACGA
AACCTCGTCCGACGGGTTCACCCCGCGACTTCTGCTGAGCTACGAAGTGAATCCCAACGTTACCGTCAACGCGCAGGCGT
CGCGCGGCTTCCGTCTCGGCGGGGTCAACGATCCGCTCAACGTGCCGCTTTGTAATGCACAGGATCTGGCCCTGTTCGGT
GGCTTCCAGGACTACGACGACGAGACGCTGTGGAACTACGAACTCGGCGTGAAAACGCAGGGCCGCAATTTCACGTTCAA
CGCCGCCGGGTTCTACAACGATATCAGCAATCTGCAGGTGACGCTCGATGCGGGCAGCTGCTCCTCCCGCATCGTGTTCA
ACGTGCCCGATGCCCACACGATGGGGATCGAAGCGGAGTTGGGCATCAGCCCTGCCGAAGGTCTCAACTTCAACCTGTCG
GGCAGCTGGATCGAGGCCGAATTCGACACCACCCTGCCGGGAGCGCTCGCGGTTGCAACCGGTATCCGCGAAGGCAACCG
CCTGCCATCGGTGCCGGAATTCCAGCTCTCCGCCTCGGGCAGTTACGAATGGCCGGTTTCGGACAATGCCGATGCCTATT
TCGCGGCATCCTTCACCCATGTCGGATCGCGCTATACCCAGCCGGCCGACCAGGAAAACAACCCGCGCACCTTCGTGCAC
GGACTGCCGTTTGCAGGTGCGCCGGCGACCGCATCGACCACGGTCGACCTGCTGCTCGACGATTACCAGCTGATCAATCT
CAGCGCGGGGATCGATTTCGACAGCGGGCTCAGCTTCGTGATCTATGCCAACAATATCCTCGACGAGAATGCGCTGCTGT
CGTTCGACCGCGAGCGCGGGGGACGTGCGCGCCTGGGCTATCGCATCGGCCAGCCGAGGACTTTCGGGATCACGGCGCGC
CAGACGTTCTGA

Upstream 100 bases:

>100_bases
AATCCGTAATATTTACGCAAAGGGAACCTTGCGGGGGCTAAGGGTGCGGCGCAGATTCCAGTGTAACGGGCGAAAAGACC
CGGTTTGCAGGAGAGATATT

Downstream 100 bases:

>100_bases
CCGCGGCGACACACAAAGAAGGGGCCGGGCAGCATCTGCTTCCCGGCCCCTTTCTTGTCGCTAGTCGCAATCAGGCGAAT
TGCTTCTCTGCGGCCATCAC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 803; Mature: 803

Protein sequence:

>803_residues
MRISESLAGFRVRSALLAGCAFALGATPALAQDSDEDTASSAPPRGNVIVVTATKRDQTIQDIPFSINAQTQEDIQRSGS
VTLEDLSRNVAGLTIQNLGPGQSQVAVRGVSAGQVVRDQPGVKEQVGVYLDESVISLSLFTPDLDLFDLNRVETLRGPQG
TLFGSGSVGGTIRYITNQPTPGIVEGTVEANFNVLESGDIGAHLKGAVNVPLLGDTITARAVGYYTEYAGFIDALGPGGG
EDINDGRRYGGRVAVRVDTGEGVSFTPRILYQKVEADGFNRQEIFNLFANPFTTTRPPVQLGEREQYLRLQEAFEDETFL
FDIVAEAELGPVTLTSVSTYINRDILVSRDASALTGSVSVDLGYPPVAVLLPSNLRDTTDLETVTQEVRLASNTDGRFQW
LVGAFYSEVDRVYTQRLPTPGYAAFTDATLGAGTSAAVANGFPNLDSPFNSDLPYDISQIAVFGEASFEVTDALTITAGG
RYYDFEETRTITTGGLFANGDSGVVDETSSDGFTPRLLLSYEVNPNVTVNAQASRGFRLGGVNDPLNVPLCNAQDLALFG
GFQDYDDETLWNYELGVKTQGRNFTFNAAGFYNDISNLQVTLDAGSCSSRIVFNVPDAHTMGIEAELGISPAEGLNFNLS
GSWIEAEFDTTLPGALAVATGIREGNRLPSVPEFQLSASGSYEWPVSDNADAYFAASFTHVGSRYTQPADQENNPRTFVH
GLPFAGAPATASTTVDLLLDDYQLINLSAGIDFDSGLSFVIYANNILDENALLSFDRERGGRARLGYRIGQPRTFGITAR
QTF

Sequences:

>Translated_803_residues
MRISESLAGFRVRSALLAGCAFALGATPALAQDSDEDTASSAPPRGNVIVVTATKRDQTIQDIPFSINAQTQEDIQRSGS
VTLEDLSRNVAGLTIQNLGPGQSQVAVRGVSAGQVVRDQPGVKEQVGVYLDESVISLSLFTPDLDLFDLNRVETLRGPQG
TLFGSGSVGGTIRYITNQPTPGIVEGTVEANFNVLESGDIGAHLKGAVNVPLLGDTITARAVGYYTEYAGFIDALGPGGG
EDINDGRRYGGRVAVRVDTGEGVSFTPRILYQKVEADGFNRQEIFNLFANPFTTTRPPVQLGEREQYLRLQEAFEDETFL
FDIVAEAELGPVTLTSVSTYINRDILVSRDASALTGSVSVDLGYPPVAVLLPSNLRDTTDLETVTQEVRLASNTDGRFQW
LVGAFYSEVDRVYTQRLPTPGYAAFTDATLGAGTSAAVANGFPNLDSPFNSDLPYDISQIAVFGEASFEVTDALTITAGG
RYYDFEETRTITTGGLFANGDSGVVDETSSDGFTPRLLLSYEVNPNVTVNAQASRGFRLGGVNDPLNVPLCNAQDLALFG
GFQDYDDETLWNYELGVKTQGRNFTFNAAGFYNDISNLQVTLDAGSCSSRIVFNVPDAHTMGIEAELGISPAEGLNFNLS
GSWIEAEFDTTLPGALAVATGIREGNRLPSVPEFQLSASGSYEWPVSDNADAYFAASFTHVGSRYTQPADQENNPRTFVH
GLPFAGAPATASTTVDLLLDDYQLINLSAGIDFDSGLSFVIYANNILDENALLSFDRERGGRARLGYRIGQPRTFGITAR
QTF
>Mature_803_residues
MRISESLAGFRVRSALLAGCAFALGATPALAQDSDEDTASSAPPRGNVIVVTATKRDQTIQDIPFSINAQTQEDIQRSGS
VTLEDLSRNVAGLTIQNLGPGQSQVAVRGVSAGQVVRDQPGVKEQVGVYLDESVISLSLFTPDLDLFDLNRVETLRGPQG
TLFGSGSVGGTIRYITNQPTPGIVEGTVEANFNVLESGDIGAHLKGAVNVPLLGDTITARAVGYYTEYAGFIDALGPGGG
EDINDGRRYGGRVAVRVDTGEGVSFTPRILYQKVEADGFNRQEIFNLFANPFTTTRPPVQLGEREQYLRLQEAFEDETFL
FDIVAEAELGPVTLTSVSTYINRDILVSRDASALTGSVSVDLGYPPVAVLLPSNLRDTTDLETVTQEVRLASNTDGRFQW
LVGAFYSEVDRVYTQRLPTPGYAAFTDATLGAGTSAAVANGFPNLDSPFNSDLPYDISQIAVFGEASFEVTDALTITAGG
RYYDFEETRTITTGGLFANGDSGVVDETSSDGFTPRLLLSYEVNPNVTVNAQASRGFRLGGVNDPLNVPLCNAQDLALFG
GFQDYDDETLWNYELGVKTQGRNFTFNAAGFYNDISNLQVTLDAGSCSSRIVFNVPDAHTMGIEAELGISPAEGLNFNLS
GSWIEAEFDTTLPGALAVATGIREGNRLPSVPEFQLSASGSYEWPVSDNADAYFAASFTHVGSRYTQPADQENNPRTFVH
GLPFAGAPATASTTVDLLLDDYQLINLSAGIDFDSGLSFVIYANNILDENALLSFDRERGGRARLGYRIGQPRTFGITAR
QTF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=220, Percent_Identity=29.0909090909091, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1790405, Length=207, Percent_Identity=29.951690821256, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 86113; Mature: 86113

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRISESLAGFRVRSALLAGCAFALGATPALAQDSDEDTASSAPPRGNVIVVTATKRDQTI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCH
QDIPFSINAQTQEDIQRSGSVTLEDLSRNVAGLTIQNLGPGQSQVAVRGVSAGQVVRDQP
HHCCEEECCCCHHHHHHCCCEEHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCEECCCC
GVKEQVGVYLDESVISLSLFTPDLDLFDLNRVETLRGPQGTLFGSGSVGGTIRYITNQPT
CCHHHHCEEECCCEEEEEEECCCCCEEECCCHHHCCCCCCEEEECCCCCCEEEEEECCCC
PGIVEGTVEANFNVLESGDIGAHLKGAVNVPLLGDTITARAVGYYTEYAGFIDALGPGGG
CCEEEEEEECCEEEEECCCCCCEECCEEECCEECCCHHHHHHHHHHHHHHHHHHCCCCCC
EDINDGRRYGGRVAVRVDTGEGVSFTPRILYQKVEADGFNRQEIFNLFANPFTTTRPPVQ
CCCCCHHHCCCEEEEEEECCCCCCCCHHHHHEECCCCCCCHHHHHHHHCCCCCCCCCCCC
LGEREQYLRLQEAFEDETFLFDIVAEAELGPVTLTSVSTYINRDILVSRDASALTGSVSV
CCCHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEHHHHHCCCEEEECCCCCEEEEEEE
DLGYPPVAVLLPSNLRDTTDLETVTQEVRLASNTDGRFQWLVGAFYSEVDRVYTQRLPTP
ECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCC
GYAAFTDATLGAGTSAAVANGFPNLDSPFNSDLPYDISQIAVFGEASFEVTDALTITAGG
CCEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHEEEEECCCEEEEEEEEEEECC
RYYDFEETRTITTGGLFANGDSGVVDETSSDGFTPRLLLSYEVNPNVTVNAQASRGFRLG
EEEECCCCEEEEECCEEECCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCEEEC
GVNDPLNVPLCNAQDLALFGGFQDYDDETLWNYELGVKTQGRNFTFNAAGFYNDISNLQV
CCCCCCCCEECCCCCEEEECCCCCCCCCEEEEEEECEEECCCEEEEECCCCCCCCCCEEE
TLDAGSCSSRIVFNVPDAHTMGIEAELGISPAEGLNFNLSGSWIEAEFDTTLPGALAVAT
EEECCCCCCEEEEECCCCCEECEEEECCCCCCCCCEEECCCCEEEEECCCCCCCHHHHHH
GIREGNRLPSVPEFQLSASGSYEWPVSDNADAYFAASFTHVGSRYTQPADQENNPRTFVH
HCCCCCCCCCCCCEEEECCCCEECCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCEEEE
GLPFAGAPATASTTVDLLLDDYQLINLSAGIDFDSGLSFVIYANNILDENALLSFDRERG
CCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEHHCCC
GRARLGYRIGQPRTFGITARQTF
CCEEEEEECCCCEEEEEEEECCC
>Mature Secondary Structure
MRISESLAGFRVRSALLAGCAFALGATPALAQDSDEDTASSAPPRGNVIVVTATKRDQTI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCH
QDIPFSINAQTQEDIQRSGSVTLEDLSRNVAGLTIQNLGPGQSQVAVRGVSAGQVVRDQP
HHCCEEECCCCHHHHHHCCCEEHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCEECCCC
GVKEQVGVYLDESVISLSLFTPDLDLFDLNRVETLRGPQGTLFGSGSVGGTIRYITNQPT
CCHHHHCEEECCCEEEEEEECCCCCEEECCCHHHCCCCCCEEEECCCCCCEEEEEECCCC
PGIVEGTVEANFNVLESGDIGAHLKGAVNVPLLGDTITARAVGYYTEYAGFIDALGPGGG
CCEEEEEEECCEEEEECCCCCCEECCEEECCEECCCHHHHHHHHHHHHHHHHHHCCCCCC
EDINDGRRYGGRVAVRVDTGEGVSFTPRILYQKVEADGFNRQEIFNLFANPFTTTRPPVQ
CCCCCHHHCCCEEEEEEECCCCCCCCHHHHHEECCCCCCCHHHHHHHHCCCCCCCCCCCC
LGEREQYLRLQEAFEDETFLFDIVAEAELGPVTLTSVSTYINRDILVSRDASALTGSVSV
CCCHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEHHHHHCCCEEEECCCCCEEEEEEE
DLGYPPVAVLLPSNLRDTTDLETVTQEVRLASNTDGRFQWLVGAFYSEVDRVYTQRLPTP
ECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCC
GYAAFTDATLGAGTSAAVANGFPNLDSPFNSDLPYDISQIAVFGEASFEVTDALTITAGG
CCEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHEEEEECCCEEEEEEEEEEECC
RYYDFEETRTITTGGLFANGDSGVVDETSSDGFTPRLLLSYEVNPNVTVNAQASRGFRLG
EEEECCCCEEEEECCEEECCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCEEEC
GVNDPLNVPLCNAQDLALFGGFQDYDDETLWNYELGVKTQGRNFTFNAAGFYNDISNLQV
CCCCCCCCEECCCCCEEEECCCCCCCCCEEEEEEECEEECCCEEEEECCCCCCCCCCEEE
TLDAGSCSSRIVFNVPDAHTMGIEAELGISPAEGLNFNLSGSWIEAEFDTTLPGALAVAT
EEECCCCCCEEEEECCCCCEECEEEECCCCCCCCCEEECCCCEEEEECCCCCCCHHHHHH
GIREGNRLPSVPEFQLSASGSYEWPVSDNADAYFAASFTHVGSRYTQPADQENNPRTFVH
HCCCCCCCCCCCCEEEECCCCEECCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCEEEE
GLPFAGAPATASTTVDLLLDDYQLINLSAGIDFDSGLSFVIYANNILDENALLSFDRERG
CCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEHHCCC
GRARLGYRIGQPRTFGITARQTF
CCEEEEEECCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]