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The map label for this gene is glpX

Identifier: 85375584

GI number: 85375584

Start: 2776719

End: 2777732

Strand: Direct

Name: glpX

Synonym: ELI_13785

Alternate gene names: 85375584

Gene position: 2776719-2777732 (Clockwise)

Preceding gene: 85375582

Following gene: 85375585

Centisome position: 90.97

GC content: 68.54

Gene sequence:

>1014_bases
ATGAACACCGCCACCGGCTCCGCCACCACGACCAAAGCCAGCTCGGTCCTCGACCGGGTGCTGGTTCTGGAAATGGTCCG
CGTCACCGAAGCCGCCGCGATCGCCGCGTCCTCGCTGATCGGGCGCGGCGACGAGAAGGCCGCCGATGCCGCCGCGGTCG
AGGCTATGCGCAAGGCGTTCGATGAGCTCTACATGGACGGCACGGTGGTGATCGGCGAGGGCGAGCGCGACGAAGCGCCG
ATGCTCTATATCGGCGAGAAGGTCGGCGGCGCGCCCGGTAAAGGCCCCAAGATCGACATCGCGCTCGACCCGCTCGAAGG
CACCACCATCACCGCCAAGGCCGGGCCCAACGCGCTCGCCGTGCTGGCAGCGGCGGAGGAAGGCTGCCTGCTCAACGCGC
CCGACACCTATATGGACAAGCTGGCGGTCGGCCCCGGCTATCCCGAGGGCATCATCGACCTGGCCAAATCGCCGACCGAC
AACGTCAAGGCCGTCGCCGAAGCCAAGGGTGTCGAGCCCTCCGACATCATCGTCTGCGTGCTCGACCGCCCGCGCCATGC
CGACCTGATCGCAGAGCTGCGTTCGCTCGGCTGCGGCGTGGTGCTAATCGGCGATGGCGATGTCGCCGGCGTGATCGCGG
TGACCGACGAAGACACCACGATCGACATGTATATGGGCCAGGGTGGCGCGCCCGAAGGCGTGCTGGCGGCAGCGGCGCTG
CGCTGTGTCGGCGGCCAGTTCAACGGGCGGCTGGTGTTCCGCAACGACGACGAGAAGGCCCGCGCCCGCAAATGGGGCAT
CCCCGACGCGGATTTCGATCGCATCTACACCCTGGAAGAGCTGGCCAAGGGCGACTGCATCTTCGCCGCCACCGGCGTCA
CTTCCGGCTCGCTGCTCGACGGCGTCAAGCGCAAACGCGGCGTTGGCGGCGCGCGGGTGATGACGACCGAAAGCGTGGTG
ATGCGGGCCAGCAGCGGCACCGTCCGCTGGATCCGGGGCGAGCACCGGATCTGA

Upstream 100 bases:

>100_bases
CGGAGCGAGCGCAAATGCGCTTATCACAACCCCCAGTCTCGACAACGCCACACTCCCGCTATAGGCGGCGGCCAAACGCA
CCAGAGGGACTGAATTCACC

Downstream 100 bases:

>100_bases
AGGTCTCGGATCCTCCCCGCTTTTGACCCAGTCACAAGTGGGGAGGGGGACCGCCAGACCGAAGGGCTGGTGGTGAAGGG
GCGTAGCGCTCCGCGAGCGT

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNTATGSATTTKASSVLDRVLVLEMVRVTEAAAIAASSLIGRGDEKAADAAAVEAMRKAFDELYMDGTVVIGEGERDEAP
MLYIGEKVGGAPGKGPKIDIALDPLEGTTITAKAGPNALAVLAAAEEGCLLNAPDTYMDKLAVGPGYPEGIIDLAKSPTD
NVKAVAEAKGVEPSDIIVCVLDRPRHADLIAELRSLGCGVVLIGDGDVAGVIAVTDEDTTIDMYMGQGGAPEGVLAAAAL
RCVGGQFNGRLVFRNDDEKARARKWGIPDADFDRIYTLEELAKGDCIFAATGVTSGSLLDGVKRKRGVGGARVMTTESVV
MRASSGTVRWIRGEHRI

Sequences:

>Translated_337_residues
MNTATGSATTTKASSVLDRVLVLEMVRVTEAAAIAASSLIGRGDEKAADAAAVEAMRKAFDELYMDGTVVIGEGERDEAP
MLYIGEKVGGAPGKGPKIDIALDPLEGTTITAKAGPNALAVLAAAEEGCLLNAPDTYMDKLAVGPGYPEGIIDLAKSPTD
NVKAVAEAKGVEPSDIIVCVLDRPRHADLIAELRSLGCGVVLIGDGDVAGVIAVTDEDTTIDMYMGQGGAPEGVLAAAAL
RCVGGQFNGRLVFRNDDEKARARKWGIPDADFDRIYTLEELAKGDCIFAATGVTSGSLLDGVKRKRGVGGARVMTTESVV
MRASSGTVRWIRGEHRI
>Mature_337_residues
MNTATGSATTTKASSVLDRVLVLEMVRVTEAAAIAASSLIGRGDEKAADAAAVEAMRKAFDELYMDGTVVIGEGERDEAP
MLYIGEKVGGAPGKGPKIDIALDPLEGTTITAKAGPNALAVLAAAEEGCLLNAPDTYMDKLAVGPGYPEGIIDLAKSPTD
NVKAVAEAKGVEPSDIIVCVLDRPRHADLIAELRSLGCGVVLIGDGDVAGVIAVTDEDTTIDMYMGQGGAPEGVLAAAAL
RCVGGQFNGRLVFRNDDEKARARKWGIPDADFDRIYTLEELAKGDCIFAATGVTSGSLLDGVKRKRGVGGARVMTTESVV
MRASSGTVRWIRGEHRI

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=335, Percent_Identity=46.5671641791045, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI1789298, Length=309, Percent_Identity=41.747572815534, Blast_Score=204, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35046; Mature: 35046

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTATGSATTTKASSVLDRVLVLEMVRVTEAAAIAASSLIGRGDEKAADAAAVEAMRKAF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DELYMDGTVVIGEGERDEAPMLYIGEKVGGAPGKGPKIDIALDPLEGTTITAKAGPNALA
HHHHCCCEEEEECCCCCCCCEEEEEHHCCCCCCCCCEEEEEECCCCCCEEEECCCCCEEE
VLAAAEEGCLLNAPDTYMDKLAVGPGYPEGIIDLAKSPTDNVKAVAEAKGVEPSDIIVCV
EEEECCCCCEECCCHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEE
LDRPRHADLIAELRSLGCGVVLIGDGDVAGVIAVTDEDTTIDMYMGQGGAPEGVLAAAAL
ECCCCCHHHHHHHHHCCCCEEEECCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHH
RCVGGQFNGRLVFRNDDEKARARKWGIPDADFDRIYTLEELAKGDCIFAATGVTSGSLLD
HHHCCCCCCEEEEECCCHHHHHHHCCCCCCCHHHEEEHHHHCCCCEEEEECCCCCCHHHH
GVKRKRGVGGARVMTTESVVMRASSGTVRWIRGEHRI
HHHHHCCCCCEEEEEEHHHEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MNTATGSATTTKASSVLDRVLVLEMVRVTEAAAIAASSLIGRGDEKAADAAAVEAMRKAF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DELYMDGTVVIGEGERDEAPMLYIGEKVGGAPGKGPKIDIALDPLEGTTITAKAGPNALA
HHHHCCCEEEEECCCCCCCCEEEEEHHCCCCCCCCCEEEEEECCCCCCEEEECCCCCEEE
VLAAAEEGCLLNAPDTYMDKLAVGPGYPEGIIDLAKSPTDNVKAVAEAKGVEPSDIIVCV
EEEECCCCCEECCCHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEE
LDRPRHADLIAELRSLGCGVVLIGDGDVAGVIAVTDEDTTIDMYMGQGGAPEGVLAAAAL
ECCCCCHHHHHHHHHCCCCEEEECCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHH
RCVGGQFNGRLVFRNDDEKARARKWGIPDADFDRIYTLEELAKGDCIFAATGVTSGSLLD
HHHCCCCCCEEEEECCCHHHHHHHCCCCCCCHHHEEEHHHHCCCCEEEEECCCCCCHHHH
GVKRKRGVGGARVMTTESVVMRASSGTVRWIRGEHRI
HHHHHCCCCCEEEEEEHHHEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]