Click here to switch to the map view.

The map label for this gene is srpC [H]

Identifier: 85375037

GI number: 85375037

Start: 2231474

End: 2232877

Strand: Direct

Name: srpC [H]

Synonym: ELI_11050

Alternate gene names: 85375037

Gene position: 2231474-2232877 (Clockwise)

Preceding gene: 85375036

Following gene: 85375043

Centisome position: 73.11

GC content: 69.59

Gene sequence:

>1404_bases
ATGCTGGCCGTTGCTGCGCTGAGCGCCTGCGTCGCCGGCCCTCCGCCGGAAATCGACACGACCCCTCCGCCGCTGCCGCT
GGAATTCGCCTTCGCGCCCGATGCGGCGACCGGCAGCGCGGTGGCATCGCTGCTGCCGACAGGCGATCCGGCCTTCCAGG
ACCTTGCCACGCTCGCGCTTCAGGATGCACCGACGCTGGCGCAGGCCGCCGCGCGGATCGAGCAGGCGCGCGCCCGCGCC
GCGGGTGCTGGAGCCAACCGCTTGCCTAATATCGGCGCGAATGCGTCGGTCACCGGCACCCGGACCAATCCCGCGCAGTT
CGGCACCAACCTGCCGCCGGGCATTTCCATCGACACCGAGCAAGTCTTCTACGGAGCCAACCTGACGGCGAGCTGGGATC
TCGACCTGTTCGGTCGCCTGCGCGCGCAGGAACGTGCGGCGCTTGCGCGGCTGGGCGCTGCGACAGTGGAAGCGACAGCG
GTGCGGAACGCGCTGCTAGCCGAGATCGCCGGCTCGGTGATCGACTGGCGCACCCTAGCCGCGCGGCAGGACGCGCTGGA
ACAGGACCTCAAAGCCGCCGCCAGTCTTGCCCGCCTGGCAGGCACGCGCGAGCGCGCCGGTCTCTCGCCCGGCTTCGACC
GCGTGCGCGCAGAAAGCGTTGCCGAGGCCACCCGCAGCCGCATCGCCGCGCTTGCGACCGACCGTGCGCGCATTGCCGGT
CGGCTCGTCGCACTGACGGGCCAGCCGGCGCAGAAGGTTCTCGACCTTTTGCGACAAACTGCACCCGATCCGGCCCAGCC
ACCTGCGCCAATGACCTTGCCGAGCCAATTGCTGGCCAATCGCCCCGATGTCGTTGCCGCCGCCGCCAATCTCGAAGCGG
CCGATGCCGATCTGGCCGCCAGCGCAGCGCGCCGCTTCCCGCAGTTCACTCTGTCTGCGGCGCTCGGCCTGCTGGCTTTC
GATCTGGGCGACCTGTTTGACGAGGACTCGATTGTCGGAAATGTCTCCGGCGGATTGGTCGCGCCGCTGCTCGATTTCGG
GCGCATTCAGGCCGAGATCGATGCTTCGGCGGCAGGCAAGCAACTGGCCTTCGCCAACTATCGCAATGCCGTCTTCACCG
CTCTCGGCGATGCCGAAGCGGGTTATGGCCTCGTCGCCGCCGCCGACCGGCAACTAGCTGCCGCATCGCGCGAATTCGCC
AGCGCGGAACGCGCCGCCGATCTCGCCGACACCCGCTATCAGGCCGGGCTGTCCGACTTCCTCACAGTGCTCGAAGCGCG
CCGCGCTGCCGATGCCAGCGGCGAGAGGGTGGCGATTGCCCGCGGTCAGGCTGAAAGGGCGCGGGTGGTGTTGTGGCAAG
CGCTTGGCGGCGATCAGCCGACCAGCCGGTCGACCAGCCAGTAG

Upstream 100 bases:

>100_bases
TCGGCCAGCAGATCGATGCCTTCATCCCCGCACGCAACGGCACTGCGCCCAAGCCCGCGCAGGCGGAGGCGGCGGAGTGA
CCGTGCGCCTCGCTCTCCCC

Downstream 100 bases:

>100_bases
GATCCGGTGATGCCGATGGCGTAACTGGCATAGCGCACCATCGGTGCCAGCGCGTCGGCGCGAATACGGCGCAGAGCTTC
GAGCACCAGCAGGACCACCG

Product: multidrug efflux system outer membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MLAVAALSACVAGPPPEIDTTPPPLPLEFAFAPDAATGSAVASLLPTGDPAFQDLATLALQDAPTLAQAAARIEQARARA
AGAGANRLPNIGANASVTGTRTNPAQFGTNLPPGISIDTEQVFYGANLTASWDLDLFGRLRAQERAALARLGAATVEATA
VRNALLAEIAGSVIDWRTLAARQDALEQDLKAAASLARLAGTRERAGLSPGFDRVRAESVAEATRSRIAALATDRARIAG
RLVALTGQPAQKVLDLLRQTAPDPAQPPAPMTLPSQLLANRPDVVAAAANLEAADADLAASAARRFPQFTLSAALGLLAF
DLGDLFDEDSIVGNVSGGLVAPLLDFGRIQAEIDASAAGKQLAFANYRNAVFTALGDAEAGYGLVAAADRQLAAASREFA
SAERAADLADTRYQAGLSDFLTVLEARRAADASGERVAIARGQAERARVVLWQALGGDQPTSRSTSQ

Sequences:

>Translated_467_residues
MLAVAALSACVAGPPPEIDTTPPPLPLEFAFAPDAATGSAVASLLPTGDPAFQDLATLALQDAPTLAQAAARIEQARARA
AGAGANRLPNIGANASVTGTRTNPAQFGTNLPPGISIDTEQVFYGANLTASWDLDLFGRLRAQERAALARLGAATVEATA
VRNALLAEIAGSVIDWRTLAARQDALEQDLKAAASLARLAGTRERAGLSPGFDRVRAESVAEATRSRIAALATDRARIAG
RLVALTGQPAQKVLDLLRQTAPDPAQPPAPMTLPSQLLANRPDVVAAAANLEAADADLAASAARRFPQFTLSAALGLLAF
DLGDLFDEDSIVGNVSGGLVAPLLDFGRIQAEIDASAAGKQLAFANYRNAVFTALGDAEAGYGLVAAADRQLAAASREFA
SAERAADLADTRYQAGLSDFLTVLEARRAADASGERVAIARGQAERARVVLWQALGGDQPTSRSTSQ
>Mature_467_residues
MLAVAALSACVAGPPPEIDTTPPPLPLEFAFAPDAATGSAVASLLPTGDPAFQDLATLALQDAPTLAQAAARIEQARARA
AGAGANRLPNIGANASVTGTRTNPAQFGTNLPPGISIDTEQVFYGANLTASWDLDLFGRLRAQERAALARLGAATVEATA
VRNALLAEIAGSVIDWRTLAARQDALEQDLKAAASLARLAGTRERAGLSPGFDRVRAESVAEATRSRIAALATDRARIAG
RLVALTGQPAQKVLDLLRQTAPDPAQPPAPMTLPSQLLANRPDVVAAAANLEAADADLAASAARRFPQFTLSAALGLLAF
DLGDLFDEDSIVGNVSGGLVAPLLDFGRIQAEIDASAAGKQLAFANYRNAVFTALGDAEAGYGLVAAADRQLAAASREFA
SAERAADLADTRYQAGLSDFLTVLEARRAADASGERVAIARGQAERARVVLWQALGGDQPTSRSTSQ

Specific function: The outer membrane component of an organic solvent efflux pump. Involved in export of a number of low log POW compounds including hexane (log POW 3.5), toluene (log POW 2.5) and dimethylphthalate (log POW 2.3). The solvent resistance phenotype has been po

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=461, Percent_Identity=25.8134490238612, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI2367348, Length=391, Percent_Identity=28.1329923273657, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48123; Mature: 48123

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVAALSACVAGPPPEIDTTPPPLPLEFAFAPDAATGSAVASLLPTGDPAFQDLATLAL
CHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHH
QDAPTLAQAAARIEQARARAAGAGANRLPNIGANASVTGTRTNPAQFGTNLPPGISIDTE
HCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCHHHCCCCCCCCCCCCHH
QVFYGANLTASWDLDLFGRLRAQERAALARLGAATVEATAVRNALLAEIAGSVIDWRTLA
HEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQDALEQDLKAAASLARLAGTRERAGLSPGFDRVRAESVAEATRSRIAALATDRARIAG
HHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RLVALTGQPAQKVLDLLRQTAPDPAQPPAPMTLPSQLLANRPDVVAAAANLEAADADLAA
EEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCHHHHHH
SAARRFPQFTLSAALGLLAFDLGDLFDEDSIVGNVSGGLVAPLLDFGRIQAEIDASAAGK
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCHHHCCC
QLAFANYRNAVFTALGDAEAGYGLVAAADRQLAAASREFASAERAADLADTRYQAGLSDF
HHHHHHHHHHHHEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LTVLEARRAADASGERVAIARGQAERARVVLWQALGGDQPTSRSTSQ
HHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLAVAALSACVAGPPPEIDTTPPPLPLEFAFAPDAATGSAVASLLPTGDPAFQDLATLAL
CHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHH
QDAPTLAQAAARIEQARARAAGAGANRLPNIGANASVTGTRTNPAQFGTNLPPGISIDTE
HCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCHHHCCCCCCCCCCCCHH
QVFYGANLTASWDLDLFGRLRAQERAALARLGAATVEATAVRNALLAEIAGSVIDWRTLA
HEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQDALEQDLKAAASLARLAGTRERAGLSPGFDRVRAESVAEATRSRIAALATDRARIAG
HHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RLVALTGQPAQKVLDLLRQTAPDPAQPPAPMTLPSQLLANRPDVVAAAANLEAADADLAA
EEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCHHHHHH
SAARRFPQFTLSAALGLLAFDLGDLFDEDSIVGNVSGGLVAPLLDFGRIQAEIDASAAGK
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCHHHCCC
QLAFANYRNAVFTALGDAEAGYGLVAAADRQLAAASREFASAERAADLADTRYQAGLSDF
HHHHHHHHHHHHEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LTVLEARRAADASGERVAIARGQAERARVVLWQALGGDQPTSRSTSQ
HHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9417051; 9852029 [H]