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The map label for this gene is degU [H]

Identifier: 85374680

GI number: 85374680

Start: 1885424

End: 1886020

Strand: Reverse

Name: degU [H]

Synonym: ELI_09265

Alternate gene names: 85374680

Gene position: 1886020-1885424 (Counterclockwise)

Preceding gene: 85374704

Following gene: 85374679

Centisome position: 61.79

GC content: 66.33

Gene sequence:

>597_bases
GTGATCGTGGGCGATGTGATGCTCTACCGGGAGGGTCTTGCCCGCGGTCTCGATCGCCTGGGCCACGTGGAGGTGGTGGA
CTCGCTGACGTCACCCGCTGCGACCGAGGCGCTAGCGGATACCCCGCCGGACATCTTGGTCCTCGACATCTCAAGTCCCG
ACACGCTCGACATCATCCGGCCCCTGATCTGTGCGCAGCCCGGCCTGCCGGTCGTCGGTTTCGGCGTCGGGGGGCAGGCC
GATGCGATGCGCTGTGCGGAGGCCGGCATTTCCTCCTTCGTGAGCCGCGAGGACAGCATCGAGGACCTGGACCAGGCGGT
GCTGATGGCTGCCCGCGGCGAAGCGGTGTGCAGCCCGCGCATGACCGCGCGGCTGATCCGGCACCTGGCCGCGCTGACCG
GCAAGGCGCACCAGCGAACGGACAATTGCCTGACGGCGCGCGAACGCGAAGTCGCCTCGCTGGTCAAGGAAGGCCTGTCG
AACAAGCAGATTGCGATCGAGCTCGGGATAAGTCCCGCCACGGTCAAGAACCACGTGCACATGATCCTGGAAAAGCTCAA
CATGCCGCGCAGGTCGTCGATCGGGATGGTGGTGTAA

Upstream 100 bases:

>100_bases
GGCAGGTCTTTTCCAGCTTGGTGGACGAGGAAAGCTGACAATGCGGAGCGGGGGAACGAACGGGAGTTCGGATCGAAGCG
CGGAGGGTCGCCCGCGGTGT

Downstream 100 bases:

>100_bases
GAAGCGGGCTTTATTCGCGCGGCGCAAATGCCTAGGCACCATGCATGGGCAAGGGAACCGGCTGGCAGTTTGCGATCGAT
CGCGGGGGGACCTTCACCGA

Product: two-component regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MIVGDVMLYREGLARGLDRLGHVEVVDSLTSPAATEALADTPPDILVLDISSPDTLDIIRPLICAQPGLPVVGFGVGGQA
DAMRCAEAGISSFVSREDSIEDLDQAVLMAARGEAVCSPRMTARLIRHLAALTGKAHQRTDNCLTAREREVASLVKEGLS
NKQIAIELGISPATVKNHVHMILEKLNMPRRSSIGMVV

Sequences:

>Translated_198_residues
MIVGDVMLYREGLARGLDRLGHVEVVDSLTSPAATEALADTPPDILVLDISSPDTLDIIRPLICAQPGLPVVGFGVGGQA
DAMRCAEAGISSFVSREDSIEDLDQAVLMAARGEAVCSPRMTARLIRHLAALTGKAHQRTDNCLTAREREVASLVKEGLS
NKQIAIELGISPATVKNHVHMILEKLNMPRRSSIGMVV
>Mature_198_residues
MIVGDVMLYREGLARGLDRLGHVEVVDSLTSPAATEALADTPPDILVLDISSPDTLDIIRPLICAQPGLPVVGFGVGGQA
DAMRCAEAGISSFVSREDSIEDLDQAVLMAARGEAVCSPRMTARLIRHLAALTGKAHQRTDNCLTAREREVASLVKEGLS
NKQIAIELGISPATVKNHVHMILEKLNMPRRSSIGMVV

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21128; Mature: 21128

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGDVMLYREGLARGLDRLGHVEVVDSLTSPAATEALADTPPDILVLDISSPDTLDIIR
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCHHHHHH
PLICAQPGLPVVGFGVGGQADAMRCAEAGISSFVSREDSIEDLDQAVLMAARGEAVCSPR
HHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCH
MTARLIRHLAALTGKAHQRTDNCLTAREREVASLVKEGLSNKQIAIELGISPATVKNHVH
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
MILEKLNMPRRSSIGMVV
HHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIVGDVMLYREGLARGLDRLGHVEVVDSLTSPAATEALADTPPDILVLDISSPDTLDIIR
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCHHHHHH
PLICAQPGLPVVGFGVGGQADAMRCAEAGISSFVSREDSIEDLDQAVLMAARGEAVCSPR
HHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCH
MTARLIRHLAALTGKAHQRTDNCLTAREREVASLVKEGLSNKQIAIELGISPATVKNHVH
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
MILEKLNMPRRSSIGMVV
HHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]