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The map label for this gene is acdA [H]

Identifier: 85374675

GI number: 85374675

Start: 1877713

End: 1878921

Strand: Reverse

Name: acdA [H]

Synonym: ELI_09240

Alternate gene names: 85374675

Gene position: 1878921-1877713 (Counterclockwise)

Preceding gene: 85374676

Following gene: 85374674

Centisome position: 61.56

GC content: 63.36

Gene sequence:

>1209_bases
ATGAACATCGATTTCGCCCCGGAACTCGAGGATTTCCGCGCCCAAGTGGCCGAATTCTTCGCCACCGCGCCGACCCCCGC
CATCCGCGAGGCGGGTCGCAAGACCACCAGCGTCTTCGCCCCGTTCAAGGAGTGCATGGAGTGGCACCGCATCCTCTACG
ACAAGGGCTGGGTCGCGCCGCACTGGCCGGAGGAATATGGCGGCACCGGCTGGAGCGTGGAGCAACGCTTCATCTTCGCC
GAGGAATACCGCAAGGCCGACCTGCCGCCGCTGCTGCCGCAGAGCCTCGGCATGGTCGGACCGCTGCTGATCGATATCGG
CACCGAGGAGCAGAAGGCAAAATACCTGGAGCCAATCCTCAAGGGCGAGGATTTCTGGGCGCAAGGTTATTCGGAGCCTA
ATTCCGGCTCAGACCTGGCCTCGCTCAGCTGCCGCGCCGAACCCGATGGCGACGATTACATCATCAACGGCTCCAAGATC
TGGACCACCTACGCGCATCACGCCAACCGCATGTTCATGCTGGTGCGCACCAGCAATGAGGGCAAGAAACAGCAGGGTAT
CACCTTCCTGTTGCTCGACCGGGTCGATTATCCCGGCATGGAAATCCGCCCCATCGTCGGGCTCGACGGCTTTCCCGAGC
AGTGTGAAGTATTCTTCGAGGATTGCCGCGTGCCGCAATCGGGCCGGGTCGGAGAGGAGAACGACGGCTGGAGCGTCGCC
AAGCACCTGCTCAAGCACGAGCGCGGCGGCGGCAATGCGGCGAGCCCAACGCTGATGCGCTATTGCGAGCGGGCGCGCGC
CGCGGCTGCGGAAACGCTCTCTCCCTTTGGTGGAAAGCTGTCGGAAGACCCGGTCTTCCAGCGCGATATAGGCGAATTGG
AGGCCGATATCGCCTCGCTCGCCCATTTCGAGAAGCTCGCCATCAGCGGCCATGAAATCGCGCGCGATCCGGCGTTCCCG
TCGATGAACAAGACGATCAATTCGGAACTGGTCCAGCGTGCCTCGACGCTGATGGCGCAGGTCTCCGGGGTCGACGGGCT
GGCGCGGCAACTTGAAGCGCTGCGGGTCGGCAGCAATGTCGAACCGCTCGGCAGCGAGTTCGATCTCATCTCCATGCCGC
TCTATCTCAACAGCCGCGCGACGACGATCTACGCAGGCTCCAACGAAGTGCAGCGCGACCTGATTGCCCGCACAGTGGCG
GGGAGCTGA

Upstream 100 bases:

>100_bases
GGCGACTATATGGGCGAACACTGGCTCGCCAGTTTCGCGCTTCTCGCCTTGCTCGCCGCGCCCGAGACTGACAGGTAGGC
GCGAGAGAGGACCCGCGCCC

Downstream 100 bases:

>100_bases
ACGATGGATTTCAGCTTCACCGAAGAGCAGGAGATGCTGCGCGACGGCGTCGGCAAGTATCTCGAGAAGAACTACGATTT
CGAAACGCGGCAGGCGCTGG

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MNIDFAPELEDFRAQVAEFFATAPTPAIREAGRKTTSVFAPFKECMEWHRILYDKGWVAPHWPEEYGGTGWSVEQRFIFA
EEYRKADLPPLLPQSLGMVGPLLIDIGTEEQKAKYLEPILKGEDFWAQGYSEPNSGSDLASLSCRAEPDGDDYIINGSKI
WTTYAHHANRMFMLVRTSNEGKKQQGITFLLLDRVDYPGMEIRPIVGLDGFPEQCEVFFEDCRVPQSGRVGEENDGWSVA
KHLLKHERGGGNAASPTLMRYCERARAAAAETLSPFGGKLSEDPVFQRDIGELEADIASLAHFEKLAISGHEIARDPAFP
SMNKTINSELVQRASTLMAQVSGVDGLARQLEALRVGSNVEPLGSEFDLISMPLYLNSRATTIYAGSNEVQRDLIARTVA
GS

Sequences:

>Translated_402_residues
MNIDFAPELEDFRAQVAEFFATAPTPAIREAGRKTTSVFAPFKECMEWHRILYDKGWVAPHWPEEYGGTGWSVEQRFIFA
EEYRKADLPPLLPQSLGMVGPLLIDIGTEEQKAKYLEPILKGEDFWAQGYSEPNSGSDLASLSCRAEPDGDDYIINGSKI
WTTYAHHANRMFMLVRTSNEGKKQQGITFLLLDRVDYPGMEIRPIVGLDGFPEQCEVFFEDCRVPQSGRVGEENDGWSVA
KHLLKHERGGGNAASPTLMRYCERARAAAAETLSPFGGKLSEDPVFQRDIGELEADIASLAHFEKLAISGHEIARDPAFP
SMNKTINSELVQRASTLMAQVSGVDGLARQLEALRVGSNVEPLGSEFDLISMPLYLNSRATTIYAGSNEVQRDLIARTVA
GS
>Mature_402_residues
MNIDFAPELEDFRAQVAEFFATAPTPAIREAGRKTTSVFAPFKECMEWHRILYDKGWVAPHWPEEYGGTGWSVEQRFIFA
EEYRKADLPPLLPQSLGMVGPLLIDIGTEEQKAKYLEPILKGEDFWAQGYSEPNSGSDLASLSCRAEPDGDDYIINGSKI
WTTYAHHANRMFMLVRTSNEGKKQQGITFLLLDRVDYPGMEIRPIVGLDGFPEQCEVFFEDCRVPQSGRVGEENDGWSVA
KHLLKHERGGGNAASPTLMRYCERARAAAAETLSPFGGKLSEDPVFQRDIGELEADIASLAHFEKLAISGHEIARDPAFP
SMNKTINSELVQRASTLMAQVSGVDGLARQLEALRVGSNVEPLGSEFDLISMPLYLNSRATTIYAGSNEVQRDLIARTVA
GS

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=365, Percent_Identity=29.041095890411, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI226958412, Length=326, Percent_Identity=27.3006134969325, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4501857, Length=405, Percent_Identity=25.1851851851852, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4501859, Length=358, Percent_Identity=27.9329608938547, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI226958414, Length=284, Percent_Identity=28.169014084507, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4557233, Length=352, Percent_Identity=26.4204545454545, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4557231, Length=403, Percent_Identity=25.8064516129032, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI187960098, Length=403, Percent_Identity=25.8064516129032, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI7656849, Length=315, Percent_Identity=27.9365079365079, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI76496475, Length=255, Percent_Identity=30.5882352941176, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4557235, Length=255, Percent_Identity=30.5882352941176, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17508101, Length=356, Percent_Identity=28.6516853932584, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17506239, Length=362, Percent_Identity=26.5193370165746, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=410, Percent_Identity=24.8780487804878, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=364, Percent_Identity=27.7472527472527, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=368, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=198, Percent_Identity=33.8383838383838, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=243, Percent_Identity=30.4526748971193, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=250, Percent_Identity=28, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=243, Percent_Identity=30.4526748971193, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=204, Percent_Identity=29.9019607843137, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=204, Percent_Identity=29.9019607843137, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=365, Percent_Identity=25.4794520547945, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=27.6752767527675, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24646207, Length=359, Percent_Identity=26.7409470752089, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281363737, Length=255, Percent_Identity=30.5882352941176, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=26.3586956521739, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355753, Length=247, Percent_Identity=30.3643724696356, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24666513, Length=358, Percent_Identity=25.6983240223464, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24660351, Length=393, Percent_Identity=25.1908396946565, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44570; Mature: 44570

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDFAPELEDFRAQVAEFFATAPTPAIREAGRKTTSVFAPFKECMEWHRILYDKGWVAP
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
HWPEEYGGTGWSVEQRFIFAEEYRKADLPPLLPQSLGMVGPLLIDIGTEEQKAKYLEPIL
CCCHHHCCCCCCHHHHEEEHHHHHCCCCCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHH
KGEDFWAQGYSEPNSGSDLASLSCRAEPDGDDYIINGSKIWTTYAHHANRMFMLVRTSNE
CCCCHHHCCCCCCCCCCCHHEEEECCCCCCCCEEECCCEEEEHHHHCCCEEEEEEEECCC
GKKQQGITFLLLDRVDYPGMEIRPIVGLDGFPEQCEVFFEDCRVPQSGRVGEENDGWSVA
CCHHCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
KHLLKHERGGGNAASPTLMRYCERARAAAAETLSPFGGKLSEDPVFQRDIGELEADIASL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
AHFEKLAISGHEIARDPAFPSMNKTINSELVQRASTLMAQVSGVDGLARQLEALRVGSNV
HHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
EPLGSEFDLISMPLYLNSRATTIYAGSNEVQRDLIARTVAGS
CCCCCCCCEEECCEEECCCCEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIDFAPELEDFRAQVAEFFATAPTPAIREAGRKTTSVFAPFKECMEWHRILYDKGWVAP
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
HWPEEYGGTGWSVEQRFIFAEEYRKADLPPLLPQSLGMVGPLLIDIGTEEQKAKYLEPIL
CCCHHHCCCCCCHHHHEEEHHHHHCCCCCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHH
KGEDFWAQGYSEPNSGSDLASLSCRAEPDGDDYIINGSKIWTTYAHHANRMFMLVRTSNE
CCCCHHHCCCCCCCCCCCHHEEEECCCCCCCCEEECCCEEEEHHHHCCCEEEEEEEECCC
GKKQQGITFLLLDRVDYPGMEIRPIVGLDGFPEQCEVFFEDCRVPQSGRVGEENDGWSVA
CCHHCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
KHLLKHERGGGNAASPTLMRYCERARAAAAETLSPFGGKLSEDPVFQRDIGELEADIASL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
AHFEKLAISGHEIARDPAFPSMNKTINSELVQRASTLMAQVSGVDGLARQLEALRVGSNV
HHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
EPLGSEFDLISMPLYLNSRATTIYAGSNEVQRDLIARTVAGS
CCCCCCCCEEECCEEECCCCEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]