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The map label for this gene is 85374657

Identifier: 85374657

GI number: 85374657

Start: 1861324

End: 1862013

Strand: Reverse

Name: 85374657

Synonym: ELI_09150

Alternate gene names: NA

Gene position: 1862013-1861324 (Counterclockwise)

Preceding gene: 85374658

Following gene: 85374656

Centisome position: 61.0

GC content: 64.49

Gene sequence:

>690_bases
ATGAGCCGACCCGTCTTTGTCCTGCGCCCGGAGCCCGGTCTCACCACCACTCTCGTGGCCGCTTTCGAGAGAGGCCTGAA
CGCGCGCGGGATGCCGCTGAGTACGGTCGAACCGGTCGCATGGAGCGCGCCAGCCAAGCCTTACGAAGGCCTGCTGATCG
GCAGCGCCAATGCTATTCGCCACGCGGGCGACGAACTGGCAAAGATCGCGCACCTGCCCGTCCTCGCGGTCGGCGAAACG
ACCGCGCAGGTCGCGCGCGAGGCGGGGTTGAAGGTAGAAATGGCCGGGACGGGCGGCCTGCAGAAAGTGCTCGAAGGTTT
GGCAGCGGATCCGCGCTCGCTTTTGCGGCTGGCGGGAGAAAAGCATCTTGAGCTCGAATTGCCGCCGCAGATCGAAGTGG
ATACGCGGATCGTCTATCGCGCCTCCTACCGGCCTCTGAATGAAGCGCAGGCCGGCCTGCTCGACGCGGACGCCGTCATG
CTGCTCCATTCGGGCGAGACGGCCGCCCATTTTTCTCAGGAATGCGAACGGCTTGGGCTCGACACATCGAAGCTTTCTCT
GGTCGCGATGGTGCCCAGGATCGCGGAAATGGCTGGAAAAGGCTGGAAAGCTCTCCACACCGCCGCATCGCCAACCGACG
ACGCAGTGTTGGAATTGGCAGCCGAGCTGTGCCAGAACCCCCGGGCATGA

Upstream 100 bases:

>100_bases
GCGAACTCGCACTGGCCGACTACGCTGCGATCGAGCGGCTTGCTGCCGACTTGCTCGATCGCGCCAGCCCGGCGATCCGC
ACCGTATTCGGCGGGGCCGC

Downstream 100 bases:

>100_bases
ATGACAGATCGCGCAGCACGAGGCGCGGCAGCGGGTCACAGAACGGAACGGGATGAACGATTTTCTGACGCAGTCCAGGC
AGGGCGGCTCTTTCCGGGCG

Product: uroporphyrinogen-III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSRPVFVLRPEPGLTTTLVAAFERGLNARGMPLSTVEPVAWSAPAKPYEGLLIGSANAIRHAGDELAKIAHLPVLAVGET
TAQVAREAGLKVEMAGTGGLQKVLEGLAADPRSLLRLAGEKHLELELPPQIEVDTRIVYRASYRPLNEAQAGLLDADAVM
LLHSGETAAHFSQECERLGLDTSKLSLVAMVPRIAEMAGKGWKALHTAASPTDDAVLELAAELCQNPRA

Sequences:

>Translated_229_residues
MSRPVFVLRPEPGLTTTLVAAFERGLNARGMPLSTVEPVAWSAPAKPYEGLLIGSANAIRHAGDELAKIAHLPVLAVGET
TAQVAREAGLKVEMAGTGGLQKVLEGLAADPRSLLRLAGEKHLELELPPQIEVDTRIVYRASYRPLNEAQAGLLDADAVM
LLHSGETAAHFSQECERLGLDTSKLSLVAMVPRIAEMAGKGWKALHTAASPTDDAVLELAAELCQNPRA
>Mature_228_residues
SRPVFVLRPEPGLTTTLVAAFERGLNARGMPLSTVEPVAWSAPAKPYEGLLIGSANAIRHAGDELAKIAHLPVLAVGETT
AQVAREAGLKVEMAGTGGLQKVLEGLAADPRSLLRLAGEKHLELELPPQIEVDTRIVYRASYRPLNEAQAGLLDADAVML
LHSGETAAHFSQECERLGLDTSKLSLVAMVPRIAEMAGKGWKALHTAASPTDDAVLELAAELCQNPRA

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 24291; Mature: 24160

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPVFVLRPEPGLTTTLVAAFERGLNARGMPLSTVEPVAWSAPAKPYEGLLIGSANAIR
CCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHH
HAGDELAKIAHLPVLAVGETTAQVAREAGLKVEMAGTGGLQKVLEGLAADPRSLLRLAGE
HHHHHHHHHHHCCEEEECHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCHHHHHHHCCC
KHLELELPPQIEVDTRIVYRASYRPLNEAQAGLLDADAVMLLHSGETAAHFSQECERLGL
CCEEEECCCCCCCCCEEEEEECCCCCHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCC
DTSKLSLVAMVPRIAEMAGKGWKALHTAASPTDDAVLELAAELCQNPRA
CHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRPVFVLRPEPGLTTTLVAAFERGLNARGMPLSTVEPVAWSAPAKPYEGLLIGSANAIR
CCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHH
HAGDELAKIAHLPVLAVGETTAQVAREAGLKVEMAGTGGLQKVLEGLAADPRSLLRLAGE
HHHHHHHHHHHCCEEEECHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCHHHHHHHCCC
KHLELELPPQIEVDTRIVYRASYRPLNEAQAGLLDADAVMLLHSGETAAHFSQECERLGL
CCEEEECCCCCCCCCEEEEEECCCCCHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCC
DTSKLSLVAMVPRIAEMAGKGWKALHTAASPTDDAVLELAAELCQNPRA
CHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA