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The map label for this gene is fprA [H]

Identifier: 85374284

GI number: 85374284

Start: 1512127

End: 1513449

Strand: Direct

Name: fprA [H]

Synonym: ELI_07285

Alternate gene names: 85374284

Gene position: 1512127-1513449 (Clockwise)

Preceding gene: 85374279

Following gene: 85374285

Centisome position: 49.54

GC content: 62.28

Gene sequence:

>1323_bases
ATGCCTGTGCGTCACATCGCCGTCGTCGGATCGGGTCCGGCAGGATATTACACCGCAGAGGCGGCTCAGAAACATTGGGG
CGAGGACGCCCGGATCGACATCTTCGACATGCTTCCGGTGCCCTACGGCCTGATCCGGACCGGGGTCGCGCCGGATCATC
AGTCGATCAAGGGTGTTTCGCGGCGCTTCGAAAAAACCAATCTTAATGAAAACGTCCGTTTCGTCGGCAATGTGTCGCTC
GGGAAAGACGTTTCTATACAAGAACTCAGCGGCCTGTACGATGCGGTGGTATTGGCTACGGGGGCTCCGCGCGATCGCGA
GCTGGATTTGCCCGGCAAGGAGCTCGGCAATATTCACGGCAGCGCTGCATTCGTCGGTTGGTATAACGGCCATCCCGAGT
TTACGAATATCGATGTCGACCTGTCGGGCAAGCACGCCGTCGTTATCGGCATGGGCAATGTGGCGCTCGATGTCGCGCGC
GTGCTGGCCAAGACCCCGCAGGAGTTCGACGGGGCCGATATCGTCCAACACGCCTATGATGCGCTGGAAGCGAGCACGAT
CGAAACCATCACCATCGTCGGGCGGCGCGGGCCGCACCAGATCATGATGACGCCCAAGGAACTGGGCGAACTGATGCATC
TCGAGCGGGCCAGCCCCTATGTCGATGCGGGCGACCTGCCGCCCGAGGAAGACGACATGATCCTCGAGCCGGGTCTCAGG
AAATCGGTCAGACTCTTGCGCGACTTCGCCGCTATCCCGGCCAGCATCCATGGCGAGACCCCGGTCACCATCGAATTCGA
CATGTTCGCCAGTCCAATCGCCTTTCACGGCGATGGCCGGGTCCGCGAAGTCGAAGTGGAGGAGACCAGAGTGGAAGCCG
GTCGCGCCATCGGCACAGGCAACACCTACCGCATCAGGGCGGACCTGGTCGTGACCTGCATCGGCTATCGCACCTCGCCG
ATTCCCGATGTGCCCTTCGACGAACGCGCGGGTCGCTTTGCCAATGACGAGGGCCGCATACTGCCCGGCATCTATTGCGT
CGGCTGGGCGCGCCGCGGACCGTCGGGCACGATCGGCACCAATCGTCCGGACGGATATGCGGTGGTCGAGAAGATCGCGG
AAGACATGGAGACTGGTGCACTCCGGCACGGCGGAAAGAAGGGCCGTGAGGGTTTCGATGCCCTTGCCGCCGAGAAAGGT
CTCGACATTGTCACCTTCCGCGACTGGAAAAAGATCGAGGAGGCCGAGGAAGCCGCCGCACGCGAAGGCGCCCCGCGCGA
AAAATTCGTCGAGATCGCGGCAATGATCGCGGCCAGGGGCTGA

Upstream 100 bases:

>100_bases
GCCGTTAGCCATGGCAGGCAGTCGCGGGAATTCTCGCCCAATCCTCGCCTCTTGTCAGTTTCATGGAGAGCGTGCATCCT
GCGTCGGTACTGGGAGGGGG

Downstream 100 bases:

>100_bases
ATGCTTGAGGACGGCAGGAAGGTGCGCGCGGCAGGAATTTTGTTTCCATGGCCAAGCACACTTGATTCTTGCTAAGGGCT
GCATCCAGAGCAATCGGATC

Product: ferredoxin/ferredoxin--NADP reductase, putative

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MPVRHIAVVGSGPAGYYTAEAAQKHWGEDARIDIFDMLPVPYGLIRTGVAPDHQSIKGVSRRFEKTNLNENVRFVGNVSL
GKDVSIQELSGLYDAVVLATGAPRDRELDLPGKELGNIHGSAAFVGWYNGHPEFTNIDVDLSGKHAVVIGMGNVALDVAR
VLAKTPQEFDGADIVQHAYDALEASTIETITIVGRRGPHQIMMTPKELGELMHLERASPYVDAGDLPPEEDDMILEPGLR
KSVRLLRDFAAIPASIHGETPVTIEFDMFASPIAFHGDGRVREVEVEETRVEAGRAIGTGNTYRIRADLVVTCIGYRTSP
IPDVPFDERAGRFANDEGRILPGIYCVGWARRGPSGTIGTNRPDGYAVVEKIAEDMETGALRHGGKKGREGFDALAAEKG
LDIVTFRDWKKIEEAEEAAAREGAPREKFVEIAAMIAARG

Sequences:

>Translated_440_residues
MPVRHIAVVGSGPAGYYTAEAAQKHWGEDARIDIFDMLPVPYGLIRTGVAPDHQSIKGVSRRFEKTNLNENVRFVGNVSL
GKDVSIQELSGLYDAVVLATGAPRDRELDLPGKELGNIHGSAAFVGWYNGHPEFTNIDVDLSGKHAVVIGMGNVALDVAR
VLAKTPQEFDGADIVQHAYDALEASTIETITIVGRRGPHQIMMTPKELGELMHLERASPYVDAGDLPPEEDDMILEPGLR
KSVRLLRDFAAIPASIHGETPVTIEFDMFASPIAFHGDGRVREVEVEETRVEAGRAIGTGNTYRIRADLVVTCIGYRTSP
IPDVPFDERAGRFANDEGRILPGIYCVGWARRGPSGTIGTNRPDGYAVVEKIAEDMETGALRHGGKKGREGFDALAAEKG
LDIVTFRDWKKIEEAEEAAAREGAPREKFVEIAAMIAARG
>Mature_439_residues
PVRHIAVVGSGPAGYYTAEAAQKHWGEDARIDIFDMLPVPYGLIRTGVAPDHQSIKGVSRRFEKTNLNENVRFVGNVSLG
KDVSIQELSGLYDAVVLATGAPRDRELDLPGKELGNIHGSAAFVGWYNGHPEFTNIDVDLSGKHAVVIGMGNVALDVARV
LAKTPQEFDGADIVQHAYDALEASTIETITIVGRRGPHQIMMTPKELGELMHLERASPYVDAGDLPPEEDDMILEPGLRK
SVRLLRDFAAIPASIHGETPVTIEFDMFASPIAFHGDGRVREVEVEETRVEAGRAIGTGNTYRIRADLVVTCIGYRTSPI
PDVPFDERAGRFANDEGRILPGIYCVGWARRGPSGTIGTNRPDGYAVVEKIAEDMETGALRHGGKKGREGFDALAAEKGL
DIVTFRDWKKIEEAEEAAAREGAPREKFVEIAAMIAARG

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=454, Percent_Identity=40.0881057268723, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI111118983, Length=460, Percent_Identity=39.5652173913043, Blast_Score=298, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI17543860, Length=442, Percent_Identity=29.185520361991, Blast_Score=195, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6320584, Length=485, Percent_Identity=28.4536082474227, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI17137178, Length=452, Percent_Identity=36.283185840708, Blast_Score=265, Evalue=4e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 47814; Mature: 47682

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRHIAVVGSGPAGYYTAEAAQKHWGEDARIDIFDMLPVPYGLIRTGVAPDHQSIKGVS
CCCEEEEEEECCCCCCEEHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCCCCHHHHHHHH
RRFEKTNLNENVRFVGNVSLGKDVSIQELSGLYDAVVLATGAPRDRELDLPGKELGNIHG
HHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHEEEEECCCCCCCCCCCCCHHHCCCCC
SAAFVGWYNGHPEFTNIDVDLSGKHAVVIGMGNVALDVARVLAKTPQEFDGADIVQHAYD
CEEEEEEECCCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ALEASTIETITIVGRRGPHQIMMTPKELGELMHLERASPYVDAGDLPPEEDDMILEPGLR
HHHCCCEEEEEEEECCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCHH
KSVRLLRDFAAIPASIHGETPVTIEFDMFASPIAFHGDGRVREVEVEETRVEAGRAIGTG
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEECCCCCEEEEEHHHHHHHCCCEECCC
NTYRIRADLVVTCIGYRTSPIPDVPFDERAGRFANDEGRILPGIYCVGWARRGPSGTIGT
CEEEEEEEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCEECCEEEEEECCCCCCCCCCC
NRPDGYAVVEKIAEDMETGALRHGGKKGREGFDALAAEKGLDIVTFRDWKKIEEAEEAAA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
REGAPREKFVEIAAMIAARG
HCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PVRHIAVVGSGPAGYYTAEAAQKHWGEDARIDIFDMLPVPYGLIRTGVAPDHQSIKGVS
CCEEEEEEECCCCCCEEHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCCCCHHHHHHHH
RRFEKTNLNENVRFVGNVSLGKDVSIQELSGLYDAVVLATGAPRDRELDLPGKELGNIHG
HHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHEEEEECCCCCCCCCCCCCHHHCCCCC
SAAFVGWYNGHPEFTNIDVDLSGKHAVVIGMGNVALDVARVLAKTPQEFDGADIVQHAYD
CEEEEEEECCCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ALEASTIETITIVGRRGPHQIMMTPKELGELMHLERASPYVDAGDLPPEEDDMILEPGLR
HHHCCCEEEEEEEECCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCHH
KSVRLLRDFAAIPASIHGETPVTIEFDMFASPIAFHGDGRVREVEVEETRVEAGRAIGTG
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEECCCCCEEEEEHHHHHHHCCCEECCC
NTYRIRADLVVTCIGYRTSPIPDVPFDERAGRFANDEGRILPGIYCVGWARRGPSGTIGT
CEEEEEEEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCEECCEEEEEECCCCCCCCCCC
NRPDGYAVVEKIAEDMETGALRHGGKKGREGFDALAAEKGLDIVTFRDWKKIEEAEEAAA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
REGAPREKFVEIAAMIAARG
HCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]