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The map label for this gene is yciK [H]

Identifier: 85374231

GI number: 85374231

Start: 1455975

End: 1456688

Strand: Direct

Name: yciK [H]

Synonym: ELI_07020

Alternate gene names: 85374231

Gene position: 1455975-1456688 (Clockwise)

Preceding gene: 85374230

Following gene: 85374232

Centisome position: 47.7

GC content: 63.45

Gene sequence:

>714_bases
ATGACTGAACAGAAATCTCTTTCGGGCAAGATTGCCCTCGTCACCGGCGCGTCCAAGGGAATTGGCGCAGCCACGGCCAA
GGCGCTCGGTGCAGCAGGCGCGCACGTGATCCTGACCGCTCGCGACGTGCGCGGGCTGGAGGAGGTCGAGGACGCGATCC
ACGATGCGGGGAGCAGTTCCACCATCGCCCCGGTCGACCTGACCGAAACGGACGGCGTCGCCCGGCTCGCCTCGGCGGTG
GCGGGACGCTGGGATGCACTCGATATTCTTGTGATTTCAGCGGCCTATCTGCCGCACCTCACACCGGTGACACAGATCGA
CCAGAAGCAGTTCAACCAGGCGCTGACGATCAATGTCCTCGCGACGCAGGCGTTGCTGGCCAATTTCGATCCGCTGCTCA
AGCGGGCCGAGGCAGGGCGCGTGATCGGGCTCACCAGCAGCGTCGGCGCCACCCCCCGCGCCTTCTGGTCTGCCTACGGC
TCCAGCAAAGCCGCCTTCGACAATCTGCTCGATAGCTATGCGCAGGAAGTCGAAAAGGTCGGCAACATCCGCGTCGCTAT
CGTCGACCCGGGCGCGACGCGCACGCAAATGCGCGCCAAGGCCTATCCGGGGGAAGACCCCAAAACGGTTAAGTCCCCGG
ATGAAGTCGCTGAAAGACTTGTTGAATTGCTTGGCGAAGACTTCGAAACCCGCCACCGCGAACGGGTTGGTTAA

Upstream 100 bases:

>100_bases
TGCCTGCTTCACCGGCGATTACCCCACCTCGCTGACCGACCTGAGCATGAAGCAGGACGGCGCGGCGCAGCTTTCTTTTC
CTGTCAACAAAGTCGCTTAA

Downstream 100 bases:

>100_bases
TGCGGCTTAACCGCCGTTGATTACCTGCGGGTAAACTGCGGTCGTCCACATAGACCTTTCACGCGCGCACCCATGCGCTT
GGAGTAGGCGGGATGACCAA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTEQKSLSGKIALVTGASKGIGAATAKALGAAGAHVILTARDVRGLEEVEDAIHDAGSSSTIAPVDLTETDGVARLASAV
AGRWDALDILVISAAYLPHLTPVTQIDQKQFNQALTINVLATQALLANFDPLLKRAEAGRVIGLTSSVGATPRAFWSAYG
SSKAAFDNLLDSYAQEVEKVGNIRVAIVDPGATRTQMRAKAYPGEDPKTVKSPDEVAERLVELLGEDFETRHRERVG

Sequences:

>Translated_237_residues
MTEQKSLSGKIALVTGASKGIGAATAKALGAAGAHVILTARDVRGLEEVEDAIHDAGSSSTIAPVDLTETDGVARLASAV
AGRWDALDILVISAAYLPHLTPVTQIDQKQFNQALTINVLATQALLANFDPLLKRAEAGRVIGLTSSVGATPRAFWSAYG
SSKAAFDNLLDSYAQEVEKVGNIRVAIVDPGATRTQMRAKAYPGEDPKTVKSPDEVAERLVELLGEDFETRHRERVG
>Mature_236_residues
TEQKSLSGKIALVTGASKGIGAATAKALGAAGAHVILTARDVRGLEEVEDAIHDAGSSSTIAPVDLTETDGVARLASAVA
GRWDALDILVISAAYLPHLTPVTQIDQKQFNQALTINVLATQALLANFDPLLKRAEAGRVIGLTSSVGATPRAFWSAYGS
SKAAFDNLLDSYAQEVEKVGNIRVAIVDPGATRTQMRAKAYPGEDPKTVKSPDEVAERLVELLGEDFETRHRERVG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=197, Percent_Identity=28.4263959390863, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI109715829, Length=232, Percent_Identity=29.3103448275862, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI32455239, Length=205, Percent_Identity=30.2439024390244, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI5031765, Length=205, Percent_Identity=30.2439024390244, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=28.1081081081081, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI20149619, Length=238, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7706318, Length=219, Percent_Identity=25.1141552511416, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787526, Length=228, Percent_Identity=33.7719298245614, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1786812, Length=228, Percent_Identity=30.7017543859649, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790717, Length=201, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=29.1666666666667, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786701, Length=211, Percent_Identity=25.5924170616114, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI2367175, Length=232, Percent_Identity=31.4655172413793, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789378, Length=195, Percent_Identity=30.7692307692308, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=221, Percent_Identity=24.8868778280543, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI87082160, Length=192, Percent_Identity=26.0416666666667, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=28.3950617283951, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=206, Percent_Identity=33.495145631068, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=217, Percent_Identity=30.4147465437788, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=198, Percent_Identity=35.3535353535354, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=206, Percent_Identity=33.9805825242718, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=197, Percent_Identity=31.4720812182741, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=240, Percent_Identity=28.75, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=201, Percent_Identity=29.8507462686567, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=205, Percent_Identity=31.219512195122, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=202, Percent_Identity=32.6732673267327, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=210, Percent_Identity=28.0952380952381, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=197, Percent_Identity=32.48730964467, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322227, Length=198, Percent_Identity=29.2929292929293, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=209, Percent_Identity=29.6650717703349, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322226, Length=192, Percent_Identity=29.1666666666667, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21358495, Length=240, Percent_Identity=31.25, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI23397609, Length=198, Percent_Identity=34.8484848484849, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355319, Length=201, Percent_Identity=27.363184079602, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=207, Percent_Identity=29.4685990338164, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571526, Length=207, Percent_Identity=29.951690821256, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=196, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25001; Mature: 24870

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQKSLSGKIALVTGASKGIGAATAKALGAAGAHVILTARDVRGLEEVEDAIHDAGSSS
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHCCCCCC
TIAPVDLTETDGVARLASAVAGRWDALDILVISAAYLPHLTPVTQIDQKQFNQALTINVL
CCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEHHH
ATQALLANFDPLLKRAEAGRVIGLTSSVGATPRAFWSAYGSSKAAFDNLLDSYAQEVEKV
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GNIRVAIVDPGATRTQMRAKAYPGEDPKTVKSPDEVAERLVELLGEDFETRHRERVG
CCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure 
TEQKSLSGKIALVTGASKGIGAATAKALGAAGAHVILTARDVRGLEEVEDAIHDAGSSS
CCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHCCCCCC
TIAPVDLTETDGVARLASAVAGRWDALDILVISAAYLPHLTPVTQIDQKQFNQALTINVL
CCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEHHH
ATQALLANFDPLLKRAEAGRVIGLTSSVGATPRAFWSAYGSSKAAFDNLLDSYAQEVEKV
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GNIRVAIVDPGATRTQMRAKAYPGEDPKTVKSPDEVAERLVELLGEDFETRHRERVG
CCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]