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The map label for this gene is sdhB

Identifier: 85374186

GI number: 85374186

Start: 1407599

End: 1408381

Strand: Direct

Name: sdhB

Synonym: ELI_06795

Alternate gene names: 85374186

Gene position: 1407599-1408381 (Clockwise)

Preceding gene: 85374184

Following gene: 85374187

Centisome position: 46.11

GC content: 60.54

Gene sequence:

>783_bases
ATGGCAACCTTCACGCTTCCCAGGAACTCCAAGATCACGGGCAAGACGCGCACCCACAAGGCCGAAAGCGGTGGCCGGGT
GAAGAAGTTCAAGATCTATCGCTACGATCCCGACAGCGGCGAGAACCCGCGCTACGACACGTTCGAAATCGATCTCGACC
AGACCGGCCCGATGGTTCTCGATGCCTTGTTCAGGATCAAGAACGAGGTCGACCCGACGCTGACCTTCCGCCGGTCGTGT
CGCGAAGGCATCTGTGGCTCATGCTCCATGAACATGAACGGCAAGAACGGCCTCGCCTGCACCACCGCGATCGAGGACTT
GAAAGGCGAAATCCGCATCACGCCGCTGCCGCATATGGAAGTGATCAAGGACCTGGTGCCCGACTTCACGCATTTCTACG
CGCAATATGCTTCGATCCGACCGTGGCTGCAGACCGTGACGCCGACGCCTTCGGGCAAGGAGCGGTTGCAATCGCCCGAA
CAGCGCGAGAAGCTAGACGGGCTTTACGAGTGCATCCTGTGCGCCTGCTGCTCGACCGCGTGCCCGAGCTATTGGTGGAA
CAGCGACAAGTTCTTGGGGCCCGCGATCCTGTTGCAGGCCTATCGCTGGCTCGCCGACAGCCGCGACGAGATGACCGGTG
AGCGGCTCGATGACCTCGAGGACCCGTTCCGCCTTTATCGCTGTCACACGATCATGAATTGCGCCAATGTCTGCCCCAAG
GGCCTGAGCCCGGCCAAGGCGATCGCCGAAACCAAGAAGATGATGGCCGAACGCACCATTTGA

Upstream 100 bases:

>100_bases
ACGCAAGTTTCAGCACACTGGGGACTTTCGCCCACCTTGCGGCGCGTGCGATATCCGCTAGATAGGCCTCAAGAAATCCA
AGCAGGACGATACGAGCGAT

Downstream 100 bases:

>100_bases
TCATCCGGGCGGCTGGCCCTATCGGGCGGGCCTATGGCGCTGAAAGACGACATCTTCGACCATCGGCCGGATCCGGACAA
TCCGGGTTGGCATCACTGGA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MATFTLPRNSKITGKTRTHKAESGGRVKKFKIYRYDPDSGENPRYDTFEIDLDQTGPMVLDALFRIKNEVDPTLTFRRSC
REGICGSCSMNMNGKNGLACTTAIEDLKGEIRITPLPHMEVIKDLVPDFTHFYAQYASIRPWLQTVTPTPSGKERLQSPE
QREKLDGLYECILCACCSTACPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDDLEDPFRLYRCHTIMNCANVCPK
GLSPAKAIAETKKMMAERTI

Sequences:

>Translated_260_residues
MATFTLPRNSKITGKTRTHKAESGGRVKKFKIYRYDPDSGENPRYDTFEIDLDQTGPMVLDALFRIKNEVDPTLTFRRSC
REGICGSCSMNMNGKNGLACTTAIEDLKGEIRITPLPHMEVIKDLVPDFTHFYAQYASIRPWLQTVTPTPSGKERLQSPE
QREKLDGLYECILCACCSTACPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDDLEDPFRLYRCHTIMNCANVCPK
GLSPAKAIAETKKMMAERTI
>Mature_259_residues
ATFTLPRNSKITGKTRTHKAESGGRVKKFKIYRYDPDSGENPRYDTFEIDLDQTGPMVLDALFRIKNEVDPTLTFRRSCR
EGICGSCSMNMNGKNGLACTTAIEDLKGEIRITPLPHMEVIKDLVPDFTHFYAQYASIRPWLQTVTPTPSGKERLQSPEQ
REKLDGLYECILCACCSTACPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDDLEDPFRLYRCHTIMNCANVCPKG
LSPAKAIAETKKMMAERTI

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=239, Percent_Identity=67.7824267782427, Blast_Score=345, Evalue=2e-95,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=57.8723404255319, Blast_Score=282, Evalue=1e-77,
Organism=Escherichia coli, GI1790596, Length=224, Percent_Identity=35.2678571428571, Blast_Score=148, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17533915, Length=254, Percent_Identity=57.8740157480315, Blast_Score=323, Evalue=4e-89,
Organism=Saccharomyces cerevisiae, GI6322987, Length=233, Percent_Identity=60.0858369098712, Blast_Score=304, Evalue=1e-83,
Organism=Drosophila melanogaster, GI17137106, Length=236, Percent_Identity=61.864406779661, Blast_Score=326, Evalue=9e-90,
Organism=Drosophila melanogaster, GI24643156, Length=234, Percent_Identity=60.6837606837607, Blast_Score=311, Evalue=2e-85,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29555; Mature: 29424

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFTLPRNSKITGKTRTHKAESGGRVKKFKIYRYDPDSGENPRYDTFEIDLDQTGPMVL
CCEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEECCCCCHHHH
DALFRIKNEVDPTLTFRRSCREGICGSCSMNMNGKNGLACTTAIEDLKGEIRITPLPHME
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHCCCCEEECCCCHHH
VIKDLVPDFTHFYAQYASIRPWLQTVTPTPSGKERLQSPEQREKLDGLYECILCACCSTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHC
CPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDDLEDPFRLYRCHTIMNCANVCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLSPAKAIAETKKMMAERTI
CCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATFTLPRNSKITGKTRTHKAESGGRVKKFKIYRYDPDSGENPRYDTFEIDLDQTGPMVL
CEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEECCCCCHHHH
DALFRIKNEVDPTLTFRRSCREGICGSCSMNMNGKNGLACTTAIEDLKGEIRITPLPHME
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHCCCCEEECCCCHHH
VIKDLVPDFTHFYAQYASIRPWLQTVTPTPSGKERLQSPEQREKLDGLYECILCACCSTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHC
CPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDDLEDPFRLYRCHTIMNCANVCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLSPAKAIAETKKMMAERTI
CCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA