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The map label for this gene is alr [H]

Identifier: 85374046

GI number: 85374046

Start: 1261874

End: 1262920

Strand: Direct

Name: alr [H]

Synonym: ELI_06095

Alternate gene names: 85374046

Gene position: 1261874-1262920 (Clockwise)

Preceding gene: 85374045

Following gene: 85374047

Centisome position: 41.34

GC content: 64.28

Gene sequence:

>1047_bases
GTGGCGATCGAGTCTCCGCCCAGAACCCTGCGTCTCGATATCGATCGCGAGGCGCTGGAGGCCAATTGGCGGGCACTCGA
TCGCTTGTCCGGCAAGGCTAGGGCAGGGGCTGCGGTCAAGGCCGACTGCTACGGGTTGGGTGTCGACACATGCGTCCCCG
TCTTGCGCGATGCGGGCGCGAGAGACTTCTTCGTAGCGCACTGGAGCGAGGTGGCCGACGTCGCGCGGCACGTACTGCCC
GAACAAATCGCGGTATTGCACGGCGCCAACACTGCCGAGGAAGCAGAGTACGCGCGCAGCATCGGCGCGCGCCCGGTAGT
CAATTCGCTGCACCAGGCAAATGTCTGGATCGATAGCGGTGGCGGCCCCTGCCACATGATGGTCGATACGGGCATTCACC
GGCTCGGGATCGCGCCGTCCGAAGTCGCTGCCAACGTCATCCGGCAACTCGATGTCCAAGTGCTTATGTCGCATCTCTCC
AGCGCTGACGAGGACACCCCTGTCAACGCAGCACAGCTCGAAGCCTTCCGCGCTCTGAAAGGTCAGTTGGGCGCACAGGA
ACTGAGCCTCGCCAACAGTGCAGGCATAGGCTTGAACGACGACTTCGCCTTCGATCTGACCCGGCCGGGTCTGTCGCTTT
ACGGCGGTGTGCAAAGGCCGGAACTGGCGGAGCATATCCGGCAAGTCGCCTATCCCAAGGCCGCGATCATTCAGGTCGCT
GAACTGCGCGCGGGCGATCACGTGGGATACAACGGCGAGTTCACCGCGCCCGACGCGATGCGGGTCGGAACGGTCTCGCT
CGGCTACGCAGACGGTTTCCTGAGAGCTTGGGGCGGCAAGGGCCTGGCGCTGTACCACGAAGGGCGATCCCTCCCGCTGC
TGGGCAAGGTTTCGATGGACATGGTGGTGGTCGACCTTGCAGCCGAGCCGGACCTGAGCGTCGGCACCTGGCTCGATGTT
CCATACGACCTCCCGCGCGCTTCCGAGGCGACCGGCCTCTCGCAATACGAACTCCTCACCATTCTGGGACAACGGTTCGC
GCGCTGA

Upstream 100 bases:

>100_bases
ACCTGGATCGTGGTCGCCATCGGTATCGTCGTCTTGTGGTGGGGCGTTCCCGACGGACCGCCGCGCGACTTCGAAGACGC
GCCGGCGACCTGACCGAGCG

Downstream 100 bases:

>100_bases
TTGCTGCACGTTGCACTGCACATATTGCAGATGCTAAGGCTCTGCTTTCTGCAGCATATTGCGCAGCATAAACTCGAGGC
GGTACTCTTCTCCATGGCGA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MAIESPPRTLRLDIDREALEANWRALDRLSGKARAGAAVKADCYGLGVDTCVPVLRDAGARDFFVAHWSEVADVARHVLP
EQIAVLHGANTAEEAEYARSIGARPVVNSLHQANVWIDSGGGPCHMMVDTGIHRLGIAPSEVAANVIRQLDVQVLMSHLS
SADEDTPVNAAQLEAFRALKGQLGAQELSLANSAGIGLNDDFAFDLTRPGLSLYGGVQRPELAEHIRQVAYPKAAIIQVA
ELRAGDHVGYNGEFTAPDAMRVGTVSLGYADGFLRAWGGKGLALYHEGRSLPLLGKVSMDMVVVDLAAEPDLSVGTWLDV
PYDLPRASEATGLSQYELLTILGQRFAR

Sequences:

>Translated_348_residues
MAIESPPRTLRLDIDREALEANWRALDRLSGKARAGAAVKADCYGLGVDTCVPVLRDAGARDFFVAHWSEVADVARHVLP
EQIAVLHGANTAEEAEYARSIGARPVVNSLHQANVWIDSGGGPCHMMVDTGIHRLGIAPSEVAANVIRQLDVQVLMSHLS
SADEDTPVNAAQLEAFRALKGQLGAQELSLANSAGIGLNDDFAFDLTRPGLSLYGGVQRPELAEHIRQVAYPKAAIIQVA
ELRAGDHVGYNGEFTAPDAMRVGTVSLGYADGFLRAWGGKGLALYHEGRSLPLLGKVSMDMVVVDLAAEPDLSVGTWLDV
PYDLPRASEATGLSQYELLTILGQRFAR
>Mature_347_residues
AIESPPRTLRLDIDREALEANWRALDRLSGKARAGAAVKADCYGLGVDTCVPVLRDAGARDFFVAHWSEVADVARHVLPE
QIAVLHGANTAEEAEYARSIGARPVVNSLHQANVWIDSGGGPCHMMVDTGIHRLGIAPSEVAANVIRQLDVQVLMSHLSS
ADEDTPVNAAQLEAFRALKGQLGAQELSLANSAGIGLNDDFAFDLTRPGLSLYGGVQRPELAEHIRQVAYPKAAIIQVAE
LRAGDHVGYNGEFTAPDAMRVGTVSLGYADGFLRAWGGKGLALYHEGRSLPLLGKVSMDMVVVDLAAEPDLSVGTWLDVP
YDLPRASEATGLSQYELLTILGQRFAR

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=368, Percent_Identity=30.9782608695652, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787439, Length=355, Percent_Identity=29.5774647887324, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 37279; Mature: 37147

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIESPPRTLRLDIDREALEANWRALDRLSGKARAGAAVKADCYGLGVDTCVPVLRDAGA
CCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEECCEEECCHHHHHHHHHCCCC
RDFFVAHWSEVADVARHVLPEQIAVLHGANTAEEAEYARSIGARPVVNSLHQANVWIDSG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCEEEECC
GGPCHMMVDTGIHRLGIAPSEVAANVIRQLDVQVLMSHLSSADEDTPVNAAQLEAFRALK
CCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GQLGAQELSLANSAGIGLNDDFAFDLTRPGLSLYGGVQRPELAEHIRQVAYPKAAIIQVA
HHCCHHHHHHHCCCCCCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
ELRAGDHVGYNGEFTAPDAMRVGTVSLGYADGFLRAWGGKGLALYHEGRSLPLLGKVSMD
HHCCCCCCCCCCCCCCCCCEEECEEEECCCCCHHHHCCCCCEEEEECCCCCCEEECCCCE
MVVVDLAAEPDLSVGTWLDVPYDLPRASEATGLSQYELLTILGQRFAR
EEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIESPPRTLRLDIDREALEANWRALDRLSGKARAGAAVKADCYGLGVDTCVPVLRDAGA
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEECCEEECCHHHHHHHHHCCCC
RDFFVAHWSEVADVARHVLPEQIAVLHGANTAEEAEYARSIGARPVVNSLHQANVWIDSG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCEEEECC
GGPCHMMVDTGIHRLGIAPSEVAANVIRQLDVQVLMSHLSSADEDTPVNAAQLEAFRALK
CCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GQLGAQELSLANSAGIGLNDDFAFDLTRPGLSLYGGVQRPELAEHIRQVAYPKAAIIQVA
HHCCHHHHHHHCCCCCCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
ELRAGDHVGYNGEFTAPDAMRVGTVSLGYADGFLRAWGGKGLALYHEGRSLPLLGKVSMD
HHCCCCCCCCCCCCCCCCCEEECEEEECCCCCHHHHCCCCCEEEEECCCCCCEEECCCCE
MVVVDLAAEPDLSVGTWLDVPYDLPRASEATGLSQYELLTILGQRFAR
EEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]