Click here to switch to the map view.

The map label for this gene is comF [H]

Identifier: 85374003

GI number: 85374003

Start: 1216739

End: 1217530

Strand: Direct

Name: comF [H]

Synonym: ELI_05880

Alternate gene names: 85374003

Gene position: 1216739-1217530 (Clockwise)

Preceding gene: 85374001

Following gene: 85374004

Centisome position: 39.86

GC content: 63.13

Gene sequence:

>792_bases
ATGAACGCGCTGCGTCTTCTCGGCGACTCGCTCGCTCCCGCAGTGGACCTGGTCTATCCGCCGCGTTGCCCGTGTTGCGG
GGATGGCATCGAGCGGCAGGAGGGGCTGTGTCTGGACTGCTGGCAAGGGCTTGTGCTCCTCGGAGAACCAAGCTGTGCCA
CATGTCGGCGCCCCATCCGCAATAGCGGCGCCGAGGAAGGAGCTGTTTGCGCAGCCTGCCTGGCCGATCCGCCGCGCCAT
TCCGGCATTTATGCCGCGACGCTGTACAATGACACCTCGCGCAGATTGGTGCTGGCCTTCAAGCACGGTCGACGCATTGC
GCTGGCAAGGATGATGGCGAAGCTGATCCAGAGGCGCCTTCCGGATCCAGGCGGGGGTTGTCTGCTGATTCCCGTACCCC
TCCATCGAAGGAGGCTTTGGGTGAGAGGCTACAATCAGGCCGCGCTACTTGCACAGGAACTAGGCAGAATCGGTGCCGGA
GTGGTCGCGGTAGATGCCTTGCGCCGGACGAAGGCCACGCCCTCGCTGGGAGGTCTCGGGCGGAAGGCGCGCGAAAGGGC
GTTGTCGGGCGCGATCGCAATCGCTCCGGCCTGGCAGCAGAAAATTGCCGGAAGGGATGTCCTACTCGTCGATGACGTCG
TAACGAGCGGCGCAACCAGCGAGCGTTGCACCCGCGTCTTGCTGAAAGCGGGCGCGAAAAGCGTTCGCATCGCAAGTTTC
ACCCGGGTATTGAGCGAGATCGAATGGCAGGCGAAAACTTCGATGGAAAACGAAACGCCCGAGGTCCGCTAA

Upstream 100 bases:

>100_bases
GCGGCGGCCTGCCGCCGGGAAAAGATGGTGGGAGGCGTATGAGCCATGAAAGTGCCGTGCCGGTCTTGCTCTCGCAGTGC
AACCGGCGCAGCATAGAAAA

Downstream 100 bases:

>100_bases
GACCCCGGGCGCCACGTGACGAAATTTGTCGGACCCGGCGGCCGTCCCCCGATGGCCGCGCGAGGGTCCAGTCCCTCATC
GTCTTGCCGAAACGGCATCA

Product: amidophosphoribosyltransferase

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNALRLLGDSLAPAVDLVYPPRCPCCGDGIERQEGLCLDCWQGLVLLGEPSCATCRRPIRNSGAEEGAVCAACLADPPRH
SGIYAATLYNDTSRRLVLAFKHGRRIALARMMAKLIQRRLPDPGGGCLLIPVPLHRRRLWVRGYNQAALLAQELGRIGAG
VVAVDALRRTKATPSLGGLGRKARERALSGAIAIAPAWQQKIAGRDVLLVDDVVTSGATSERCTRVLLKAGAKSVRIASF
TRVLSEIEWQAKTSMENETPEVR

Sequences:

>Translated_263_residues
MNALRLLGDSLAPAVDLVYPPRCPCCGDGIERQEGLCLDCWQGLVLLGEPSCATCRRPIRNSGAEEGAVCAACLADPPRH
SGIYAATLYNDTSRRLVLAFKHGRRIALARMMAKLIQRRLPDPGGGCLLIPVPLHRRRLWVRGYNQAALLAQELGRIGAG
VVAVDALRRTKATPSLGGLGRKARERALSGAIAIAPAWQQKIAGRDVLLVDDVVTSGATSERCTRVLLKAGAKSVRIASF
TRVLSEIEWQAKTSMENETPEVR
>Mature_263_residues
MNALRLLGDSLAPAVDLVYPPRCPCCGDGIERQEGLCLDCWQGLVLLGEPSCATCRRPIRNSGAEEGAVCAACLADPPRH
SGIYAATLYNDTSRRLVLAFKHGRRIALARMMAKLIQRRLPDPGGGCLLIPVPLHRRRLWVRGYNQAALLAQELGRIGAG
VVAVDALRRTKATPSLGGLGRKARERALSGAIAIAPAWQQKIAGRDVLLVDDVVTSGATSERCTRVLLKAGAKSVRIASF
TRVLSEIEWQAKTSMENETPEVR

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=231, Percent_Identity=29.004329004329, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 28395; Mature: 28395

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALRLLGDSLAPAVDLVYPPRCPCCGDGIERQEGLCLDCWQGLVLLGEPSCATCRRPIR
CCHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHH
NSGAEEGAVCAACLADPPRHSGIYAATLYNDTSRRLVLAFKHGRRIALARMMAKLIQRRL
CCCCCCCCEEHHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHC
PDPGGGCLLIPVPLHRRRLWVRGYNQAALLAQELGRIGAGVVAVDALRRTKATPSLGGLG
CCCCCCEEEEECCCCHHEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
RKARERALSGAIAIAPAWQQKIAGRDVLLVDDVVTSGATSERCTRVLLKAGAKSVRIASF
HHHHHHHHHCCEEECCHHHHHHCCCCEEEEHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
TRVLSEIEWQAKTSMENETPEVR
HHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNALRLLGDSLAPAVDLVYPPRCPCCGDGIERQEGLCLDCWQGLVLLGEPSCATCRRPIR
CCHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHH
NSGAEEGAVCAACLADPPRHSGIYAATLYNDTSRRLVLAFKHGRRIALARMMAKLIQRRL
CCCCCCCCEEHHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHC
PDPGGGCLLIPVPLHRRRLWVRGYNQAALLAQELGRIGAGVVAVDALRRTKATPSLGGLG
CCCCCCEEEEECCCCHHEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
RKARERALSGAIAIAPAWQQKIAGRDVLLVDDVVTSGATSERCTRVLLKAGAKSVRIASF
HHHHHHHHHCCEEECCHHHHHHCCCCEEEEHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
TRVLSEIEWQAKTSMENETPEVR
HHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]