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The map label for this gene is ctaC [H]

Identifier: 84625577

GI number: 84625577

Start: 4419072

End: 4420025

Strand: Reverse

Name: ctaC [H]

Synonym: XOO_3920

Alternate gene names: 84625577

Gene position: 4420025-4419072 (Counterclockwise)

Preceding gene: 84625578

Following gene: 84625576

Centisome position: 89.47

GC content: 65.09

Gene sequence:

>954_bases
ATGACGCAACGCAGCAGCTTGACGTCGATGAGCATTTCCACACAGGTGGGCCTGGCGATGGCAGCGCTGCTGAGCGCACC
GGCCGCCTGGGCGCAATCGGCCGATCCCAAGGAATGGCAGCTCAACATGGGGCGCGGGGTGACCCAGACCGCGCATATGG
CCTACGAGGCGCATATGGTGGCGCTGTGGGTGTGCGTGGTGATCGGCGCGCTGGTGTTCGGCGCGATGGGCTATGCGATC
TTCACGTTCCGCAAGTCCAAAGGCGCGGTGGCTGCGCAATTCAGTCACAACACCACCGCTGAAGCGCTATGGACGGTGAT
TCCGGTGCTGGTGCTGATCGCGATGGCCTGGCCGGCGACGGCAAAGCTGATCGCGATGTACGACACCCGCGAATCGGAAA
TGACGGTCAAGGTGACCGGCTACCAATGGATGTGGAAATACGAGTATCTCGGCCAGGGTGTGGCATTCACCAGTCGCCTG
GCACGCGAATCCGATCGCATCCGGCAAAGCGGCGAGCGCCCGATCGCGGCCTCGCAGCCGCACTACCTGCTGGATGTCGA
CAACCACCTGGTGCTGCCGGTCAACACCAAGATCCGGTTCGTGATTACCGCCGACGACGTGATCCATGCCTGGTGGGTGC
CCGCGCTGGGATGGAAGCAGGACGCGATCCCCGGCATCGTCAACGAAGCCTGGACCAACATCGAACAGCCGGGCGTGTAT
CGCGGGCAGTGCGCCGAGTTGTGCGGCAAGGATCATGGCTTCATGCCGATCGTGGTGGAAGTGCTGCCCAAGGCCGAATT
CCAGCGCTGGCTGGCGTCGCGTCGCAGCGCGTCAGGCACTGCTCCGGCAGCGGCGCCTGCGGGTCCAGCCGCCGCACCGC
CGTCCGCTGCACCGGCGACGCCTGCAGGTGATGCCGCGCCTGCCGCAGCTGCTACACCGACCGCCGCTCTTTAA

Upstream 100 bases:

>100_bases
AGTTTTCTCGGGCCGGCCGAACGTGTGGAACTGGCAATGACGCTCAAACGCTTGCTAGCGGCCGCCAATGGCCGTTACCG
ATGACGTAAGGGTCTAGGCA

Downstream 100 bases:

>100_bases
TCGCTCGCAACCGCTCGTTTCGCAGAGGTCGTTCCGTCATGGCGCATACCGCAGTCGATCACCACGGACACCACCAGCCC
GGTTTCGTCGAGCGCTGGTT

Product: cytochrome C oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTQRSSLTSMSISTQVGLAMAALLSAPAAWAQSADPKEWQLNMGRGVTQTAHMAYEAHMVALWVCVVIGALVFGAMGYAI
FTFRKSKGAVAAQFSHNTTAEALWTVIPVLVLIAMAWPATAKLIAMYDTRESEMTVKVTGYQWMWKYEYLGQGVAFTSRL
ARESDRIRQSGERPIAASQPHYLLDVDNHLVLPVNTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTNIEQPGVY
RGQCAELCGKDHGFMPIVVEVLPKAEFQRWLASRRSASGTAPAAAPAGPAAAPPSAAPATPAGDAAPAAAATPTAAL

Sequences:

>Translated_317_residues
MTQRSSLTSMSISTQVGLAMAALLSAPAAWAQSADPKEWQLNMGRGVTQTAHMAYEAHMVALWVCVVIGALVFGAMGYAI
FTFRKSKGAVAAQFSHNTTAEALWTVIPVLVLIAMAWPATAKLIAMYDTRESEMTVKVTGYQWMWKYEYLGQGVAFTSRL
ARESDRIRQSGERPIAASQPHYLLDVDNHLVLPVNTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTNIEQPGVY
RGQCAELCGKDHGFMPIVVEVLPKAEFQRWLASRRSASGTAPAAAPAGPAAAPPSAAPATPAGDAAPAAAATPTAAL
>Mature_316_residues
TQRSSLTSMSISTQVGLAMAALLSAPAAWAQSADPKEWQLNMGRGVTQTAHMAYEAHMVALWVCVVIGALVFGAMGYAIF
TFRKSKGAVAAQFSHNTTAEALWTVIPVLVLIAMAWPATAKLIAMYDTRESEMTVKVTGYQWMWKYEYLGQGVAFTSRLA
RESDRIRQSGERPIAASQPHYLLDVDNHLVLPVNTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTNIEQPGVYR
GQCAELCGKDHGFMPIVVEVLPKAEFQRWLASRRSASGTAPAAAPAGPAAAPPSAAPATPAGDAAPAAAATPTAAL

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RPE1 insert domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=173, Percent_Identity=40.4624277456647, Blast_Score=142, Evalue=6e-34,
Organism=Escherichia coli, GI1786635, Length=241, Percent_Identity=24.4813278008299, Blast_Score=61, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6226540, Length=226, Percent_Identity=36.283185840708, Blast_Score=142, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- InterPro:   IPR005728 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 34014; Mature: 33883

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRSSLTSMSISTQVGLAMAALLSAPAAWAQSADPKEWQLNMGRGVTQTAHMAYEAHMV
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHH
ALWVCVVIGALVFGAMGYAIFTFRKSKGAVAAQFSHNTTAEALWTVIPVLVLIAMAWPAT
HHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
AKLIAMYDTRESEMTVKVTGYQWMWKYEYLGQGVAFTSRLARESDRIRQSGERPIAASQP
EEEEEEEECCCCCEEEEEECEEEEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
HYLLDVDNHLVLPVNTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTNIEQPGVY
CEEEECCCEEEEEECCEEEEEEEECCHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCC
RGQCAELCGKDHGFMPIVVEVLPKAEFQRWLASRRSASGTAPAAAPAGPAAAPPSAAPAT
CHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PAGDAAPAAAATPTAAL
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQRSSLTSMSISTQVGLAMAALLSAPAAWAQSADPKEWQLNMGRGVTQTAHMAYEAHMV
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHH
ALWVCVVIGALVFGAMGYAIFTFRKSKGAVAAQFSHNTTAEALWTVIPVLVLIAMAWPAT
HHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
AKLIAMYDTRESEMTVKVTGYQWMWKYEYLGQGVAFTSRLARESDRIRQSGERPIAASQP
EEEEEEEECCCCCEEEEEECEEEEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
HYLLDVDNHLVLPVNTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTNIEQPGVY
CEEEECCCEEEEEECCEEEEEEEECCHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCC
RGQCAELCGKDHGFMPIVVEVLPKAEFQRWLASRRSASGTAPAAAPAGPAAAPPSAAPAT
CHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PAGDAAPAAAATPTAAL
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893; 11030655 [H]