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The map label for this gene is corA [H]

Identifier: 84625459

GI number: 84625459

Start: 4302367

End: 4303278

Strand: Reverse

Name: corA [H]

Synonym: XOO_3802

Alternate gene names: 84625459

Gene position: 4303278-4302367 (Counterclockwise)

Preceding gene: 84625461

Following gene: 84625457

Centisome position: 87.11

GC content: 63.05

Gene sequence:

>912_bases
ATGATCACGATCCACCCGATTGCCGGAACCCGGCACACCCCAGGCTGCTGGGTCGACCTGTGCCAGCCGATCCCGCAAGA
GCTGGCGCAAGCCGCTGAGAAGGTGGGGTTTGCCTTGCCCGATCGTGCGGCGATTGGCGAGATCGAATTCAGCAGCCGGG
TGCGCCGCCAGGGCGATGTGTTGTTTCTCAATGTGCCGCGGTTCCAGGACGAGGATGGCCCCACGGCGCCGTTGGGGTTC
GCGCTCTCACCCACCATGCTGGTGACCTTGCGTGAGCAGCGCATCGGCTCGTTGGAGGCCTTGACCGCCGGGCTGGAACA
CGAGCCCTGCCACAGCGCGGACGATTTGCTGCTACGCATGTTCGACCACCTGGTCGGACGGCTGGCCGACCGGCTTGAGG
CGCTCGAAGCGGCGGTCACCGAGACCACGCGGCAAGTGTTCGATAGCCCACACAAAACCAAGGATCTGGAGCGCATGTTG
CACCAGGTCGGCGACATGGGCCGGCAGCTTGGCGGCTTGCACAACGCAGGGCAAGGCATGCAGCGTCTGGTCACTTATCT
AGATGGCGCCGCCCCGGATTGGTTCGCTGCCGATGCAGCCAAACGCATCACCCTGCTGCACAAGGATCTGACCACCTTAA
GCGAATTCCAGCAGCACATGGACGACCGCATCGAGTTCCTGCTCGACAGCGTGCTGGGCATGATCAACATGGACCAGAAC
AACGTGATGAAGGTGATGGCCGTCGCGTCGGTGGTCGGTATCCCGCCCACCGTGCTGGTCGGCATCTGGGGCATGAACTT
CTCTTACATGCCCGAACTCAAGGGGCACGACCACTACTTCTGGGCACTGGGCATCATCGCACTGAGCGTGGTGGTGCCGC
TGGCGTGGTTTCGCAAGCGTGGATGGGTGTGA

Upstream 100 bases:

>100_bases
CCATCGCGGCCGTTGCCTCCGTCGCCGATGGGCATGTGCCGGCGTTGACGCCATGGTGGACGCGGAGGATGCTGGGGCTC
TTTGATCTCACAGTCGATGC

Downstream 100 bases:

>100_bases
TGCATCAGTGCCCGGAACTGCAGGAGTGCTCCTGAGCGCGATATGGCGTTACCGGGAAGGCCATATCGCCCGGGTGCGTT
CCTACGGCGATCAACTGCAG

Product: magnesium and cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MITIHPIAGTRHTPGCWVDLCQPIPQELAQAAEKVGFALPDRAAIGEIEFSSRVRRQGDVLFLNVPRFQDEDGPTAPLGF
ALSPTMLVTLREQRIGSLEALTAGLEHEPCHSADDLLLRMFDHLVGRLADRLEALEAAVTETTRQVFDSPHKTKDLERML
HQVGDMGRQLGGLHNAGQGMQRLVTYLDGAAPDWFAADAAKRITLLHKDLTTLSEFQQHMDDRIEFLLDSVLGMINMDQN
NVMKVMAVASVVGIPPTVLVGIWGMNFSYMPELKGHDHYFWALGIIALSVVVPLAWFRKRGWV

Sequences:

>Translated_303_residues
MITIHPIAGTRHTPGCWVDLCQPIPQELAQAAEKVGFALPDRAAIGEIEFSSRVRRQGDVLFLNVPRFQDEDGPTAPLGF
ALSPTMLVTLREQRIGSLEALTAGLEHEPCHSADDLLLRMFDHLVGRLADRLEALEAAVTETTRQVFDSPHKTKDLERML
HQVGDMGRQLGGLHNAGQGMQRLVTYLDGAAPDWFAADAAKRITLLHKDLTTLSEFQQHMDDRIEFLLDSVLGMINMDQN
NVMKVMAVASVVGIPPTVLVGIWGMNFSYMPELKGHDHYFWALGIIALSVVVPLAWFRKRGWV
>Mature_303_residues
MITIHPIAGTRHTPGCWVDLCQPIPQELAQAAEKVGFALPDRAAIGEIEFSSRVRRQGDVLFLNVPRFQDEDGPTAPLGF
ALSPTMLVTLREQRIGSLEALTAGLEHEPCHSADDLLLRMFDHLVGRLADRLEALEAAVTETTRQVFDSPHKTKDLERML
HQVGDMGRQLGGLHNAGQGMQRLVTYLDGAAPDWFAADAAKRITLLHKDLTTLSEFQQHMDDRIEFLLDSVLGMINMDQN
NVMKVMAVASVVGIPPTVLVGIWGMNFSYMPELKGHDHYFWALGIIALSVVVPLAWFRKRGWV

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=294, Percent_Identity=24.1496598639456, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 33693; Mature: 33693

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIHPIAGTRHTPGCWVDLCQPIPQELAQAAEKVGFALPDRAAIGEIEFSSRVRRQGDV
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHCCCE
LFLNVPRFQDEDGPTAPLGFALSPTMLVTLREQRIGSLEALTAGLEHEPCHSADDLLLRM
EEEECCCCCCCCCCCCCCCCCCCCHHHEEEHHHHHCHHHHHHHCCCCCCCCCHHHHHHHH
FDHLVGRLADRLEALEAAVTETTRQVFDSPHKTKDLERMLHQVGDMGRQLGGLHNAGQGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QRLVTYLDGAAPDWFAADAAKRITLLHKDLTTLSEFQQHMDDRIEFLLDSVLGMINMDQN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
NVMKVMAVASVVGIPPTVLVGIWGMNFSYMPELKGHDHYFWALGIIALSVVVPLAWFRKR
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GWV
CCC
>Mature Secondary Structure
MITIHPIAGTRHTPGCWVDLCQPIPQELAQAAEKVGFALPDRAAIGEIEFSSRVRRQGDV
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHCCCE
LFLNVPRFQDEDGPTAPLGFALSPTMLVTLREQRIGSLEALTAGLEHEPCHSADDLLLRM
EEEECCCCCCCCCCCCCCCCCCCCHHHEEEHHHHHCHHHHHHHCCCCCCCCCHHHHHHHH
FDHLVGRLADRLEALEAAVTETTRQVFDSPHKTKDLERMLHQVGDMGRQLGGLHNAGQGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QRLVTYLDGAAPDWFAADAAKRITLLHKDLTTLSEFQQHMDDRIEFLLDSVLGMINMDQN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
NVMKVMAVASVVGIPPTVLVGIWGMNFSYMPELKGHDHYFWALGIIALSVVVPLAWFRKR
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GWV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]