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The map label for this gene is yegE [H]

Identifier: 84625449

GI number: 84625449

Start: 4287131

End: 4289755

Strand: Reverse

Name: yegE [H]

Synonym: XOO_3792

Alternate gene names: 84625449

Gene position: 4289755-4287131 (Counterclockwise)

Preceding gene: 84625452

Following gene: 84625445

Centisome position: 86.83

GC content: 66.02

Gene sequence:

>2625_bases
ATGACCGTCCTGTTGCCGCCCGTGCCGATCCCCGTCGACGATGCCTTGCGCGTGGACGCGGTGCGCCGGCTCGGGGTACT
GGACACCGAGGCCGAGGCCGAATTCGACGACATCGCCTGGCTGGCCGCGCACGTCACCGGCGCGCCGGTGGCACTGGTGT
CGCTGCTGGATGCCGACCGCCAGTGGTTCAAGGCGCGTTGCGGCAGCGACCTGGAAGGCACTCCGCGCAGCGCCTCGTTT
TGCTCCCACGCGATCATGGGCACCGAGTTGATGGAAGTGCCCGATGCCGAAGCCGACCCGCGCTTCGTCAACAACCCGTT
GGTGGTCGGCGCCCCCGGCGTGCGCTCGTACGTGGGGGTACCGTTGATCGGGCGCGAAGGCTATGCCTACGGGACCTTGT
GCACGCTCAGCACCAGGCCGCGCGTGCTCGACGAACAGCAGAAGCAGGCGTTGATCCGCCTTGCGCGCCAGGCTGCCAAA
CAGTTGGAAGCGCGCCGCGACCGCCTGGAAGCGCAGGCGCAGCGGCAGACCTTGAGCATGTTGCTGGAAGCCATGCCCGA
CGGCGTGGTGGCCTGCGGCACCGACGGATTGCTGCGCGAGTTCAATCACGCCGCCCGGCAATGGCATGGCACCGATCCGC
GCCTGTTGCCACCGGAGCAATGGGCGTTGCATTTCGATCTGTACACGGCCGACGGCACTCACCTGCTGCCGACCGAAGCG
ATTCCGCTGCTGCGCGCCTGGCGCGGCGAACACGTGCGCAATGCCGAAATGGTGATCCGTGCCACCGGCCAGCCGCCGCG
CAGCGTGCTGTGCAACGCAGACCCGGTGGTCGGCGACAACGGCACGGCCTTGGGCGCGGTCTGCGTGATGCACGACATCA
CCCAGCTCAAGGATGCGTCGGCGGCACTGGCCGGCGAACGCGCGCGGCTGCAGGCACTGGTGGACGCGTCGCAAGATGTG
GCCATCATGGCGTTCGACCCGCAGGGACGTCTGGAACTGTTCAATCCCGGTGCCGAGCGCCTGCTCGGTTACAGTGCCGA
CGAGGTGCTGGGCACCTGTCCGGCGCAGTTCCATCTACCGGCCGAGCTTGAGCGCCACATGGCGACGCTGGCAGTGGCGC
CATTCTCATACGCGACGCTGGCTGCCGCCGCCGCTGGCGATGTGCTGGCCGAGGAACTCTGGACACTGGTACGCAAGGAC
GGCGATCTGCGGCGCGTGCGCCTGTGTTTCAACGTCATCCACGATGCGCAGCAGGGCCTGGCCGGATATCTGGCAATGGC
CATCGACGTCACTGCCGAATTGCAGGCGCAAGCGGCCGCGCAGCTGGCCGCCGAGCGCTTCACCGGTGCATTCGAGACAG
CGCCGCAAGGCATGGCGATCGTGTCGCTGGAAGGTGAGTGGTGCGACGTCAATCCGGCGTTGTGCGGCATCCTGGGCTAT
GCGCGCGAGCAATTGTTGCGCACGACTTTCCAGCAGATTACCCATCCCGACGATCTGGAGATGGACCTGCAACTCGTGCA
GGATCTCGTCGACGGAAAACGCGCCAGTTACAGCCTGGCCAAGCGCTACATCAGCCACCAGGGCGCGGTGATCTGGGCGC
AGTTGTCGGTATCGCTGGTGCGCGACAGCAGCGGTGCGCCGGTGCATTTCGTTTCGCAGATTCAAGACGTGACCGAGCGC
CACGTGGCGGCCGAACGGCTGGCCGAAAGCGAGGCGCGTCTGCGCGCGATCAGCGATGCCACGCCCACGTTGGTTGCCCA
GTTCGATGCCGGGCAGCGCTACCTGTTCGCCAATAAAGCGCATCGCGCCTGGCTCGGTATGGAACCTGCCAGCCTGGTCG
GTCGCCATATCACCCACGTGTTGGGCGAAGACCTCAGCGCCGCCGCGCGCGCTGCATTGGTACAGGCGGTGGCCGGGCAG
CGCGCCAGCTTCGAACATGTCTTGCATGGCGGCACCAACCCGCGCGATGTGGAAGTGAGCCTGGTGCCGGAAATGCACGG
CACTGCGACGCAGGCGCAGGGTTTCTTCCTGATGGCGCACGATGTCACTGCGCACAAGACACTGCACCGTTTGATGCACC
AACGCGCTACCCGTGATGCGTTGACCGGACTGCCGAACCGGCATGCCTGGTCCGAAGCGCTGCAAGTGGCAATGACACAG
GCGCATCAACAGCAGCTCGCGGTGGCGGTGATGTTCCTGGATTTGGATGGCTTCAAACGCATCAACGACATCTACAGCCA
CCGTGCCGGCGATGCAGTGTTGGTGGCGTTCGGCCATTGCCTGCAGCGCGCGGCTGGTGAGCGCTATTTGGTGGCGCGCT
TGGCCGGCGACGAATTCGTGGTGTTGCTGGATGCGCTGCAGGATCCGCAAGCCGAATGCGCCACGATGGCAGATCGCATC
CGCGCGCTTGCGGCGGAAGGCGCCATGTTCGGCGATCAGCATCTACCGATCCAGCCCAGCATCGGTGTGGCCTGGCAACA
CGGCGCACAGGCCGAAGCGGCCAGCTTGATGCATGCCGCTGACGAGGCGATGTATGCGGCCAAACGCGCACGGCGGCCAG
CTGAGCAGGCCGTTGCGGCAGTAAGCGTTGTGGGTTGCTGGTGCAAGCCAGTGCGTTGCTGCTGA

Upstream 100 bases:

>100_bases
TTTTCCGAGCGAGCTCGGCAGCACGCTGCTCAAGTTCCTCGTCGCCTCGCCGTTACTTGGGGCGACCTATCCTGACCAGA
CGCTACCCGCCGATCACGCC

Downstream 100 bases:

>100_bases
CGCGTGCGCACGGCTGGCGCGAATCGCGAACTTCCAACTCTCAACCCCTGCAGCGTTCGCGTTGTTACAACGCAACGATG
CGTGCGTTCTTGCCAGGGAA

Product: histidine kinase-response regulator hybrid protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 874; Mature: 873

Protein sequence:

>874_residues
MTVLLPPVPIPVDDALRVDAVRRLGVLDTEAEAEFDDIAWLAAHVTGAPVALVSLLDADRQWFKARCGSDLEGTPRSASF
CSHAIMGTELMEVPDAEADPRFVNNPLVVGAPGVRSYVGVPLIGREGYAYGTLCTLSTRPRVLDEQQKQALIRLARQAAK
QLEARRDRLEAQAQRQTLSMLLEAMPDGVVACGTDGLLREFNHAARQWHGTDPRLLPPEQWALHFDLYTADGTHLLPTEA
IPLLRAWRGEHVRNAEMVIRATGQPPRSVLCNADPVVGDNGTALGAVCVMHDITQLKDASAALAGERARLQALVDASQDV
AIMAFDPQGRLELFNPGAERLLGYSADEVLGTCPAQFHLPAELERHMATLAVAPFSYATLAAAAAGDVLAEELWTLVRKD
GDLRRVRLCFNVIHDAQQGLAGYLAMAIDVTAELQAQAAAQLAAERFTGAFETAPQGMAIVSLEGEWCDVNPALCGILGY
AREQLLRTTFQQITHPDDLEMDLQLVQDLVDGKRASYSLAKRYISHQGAVIWAQLSVSLVRDSSGAPVHFVSQIQDVTER
HVAAERLAESEARLRAISDATPTLVAQFDAGQRYLFANKAHRAWLGMEPASLVGRHITHVLGEDLSAAARAALVQAVAGQ
RASFEHVLHGGTNPRDVEVSLVPEMHGTATQAQGFFLMAHDVTAHKTLHRLMHQRATRDALTGLPNRHAWSEALQVAMTQ
AHQQQLAVAVMFLDLDGFKRINDIYSHRAGDAVLVAFGHCLQRAAGERYLVARLAGDEFVVLLDALQDPQAECATMADRI
RALAAEGAMFGDQHLPIQPSIGVAWQHGAQAEAASLMHAADEAMYAAKRARRPAEQAVAAVSVVGCWCKPVRCC

Sequences:

>Translated_874_residues
MTVLLPPVPIPVDDALRVDAVRRLGVLDTEAEAEFDDIAWLAAHVTGAPVALVSLLDADRQWFKARCGSDLEGTPRSASF
CSHAIMGTELMEVPDAEADPRFVNNPLVVGAPGVRSYVGVPLIGREGYAYGTLCTLSTRPRVLDEQQKQALIRLARQAAK
QLEARRDRLEAQAQRQTLSMLLEAMPDGVVACGTDGLLREFNHAARQWHGTDPRLLPPEQWALHFDLYTADGTHLLPTEA
IPLLRAWRGEHVRNAEMVIRATGQPPRSVLCNADPVVGDNGTALGAVCVMHDITQLKDASAALAGERARLQALVDASQDV
AIMAFDPQGRLELFNPGAERLLGYSADEVLGTCPAQFHLPAELERHMATLAVAPFSYATLAAAAAGDVLAEELWTLVRKD
GDLRRVRLCFNVIHDAQQGLAGYLAMAIDVTAELQAQAAAQLAAERFTGAFETAPQGMAIVSLEGEWCDVNPALCGILGY
AREQLLRTTFQQITHPDDLEMDLQLVQDLVDGKRASYSLAKRYISHQGAVIWAQLSVSLVRDSSGAPVHFVSQIQDVTER
HVAAERLAESEARLRAISDATPTLVAQFDAGQRYLFANKAHRAWLGMEPASLVGRHITHVLGEDLSAAARAALVQAVAGQ
RASFEHVLHGGTNPRDVEVSLVPEMHGTATQAQGFFLMAHDVTAHKTLHRLMHQRATRDALTGLPNRHAWSEALQVAMTQ
AHQQQLAVAVMFLDLDGFKRINDIYSHRAGDAVLVAFGHCLQRAAGERYLVARLAGDEFVVLLDALQDPQAECATMADRI
RALAAEGAMFGDQHLPIQPSIGVAWQHGAQAEAASLMHAADEAMYAAKRARRPAEQAVAAVSVVGCWCKPVRCC
>Mature_873_residues
TVLLPPVPIPVDDALRVDAVRRLGVLDTEAEAEFDDIAWLAAHVTGAPVALVSLLDADRQWFKARCGSDLEGTPRSASFC
SHAIMGTELMEVPDAEADPRFVNNPLVVGAPGVRSYVGVPLIGREGYAYGTLCTLSTRPRVLDEQQKQALIRLARQAAKQ
LEARRDRLEAQAQRQTLSMLLEAMPDGVVACGTDGLLREFNHAARQWHGTDPRLLPPEQWALHFDLYTADGTHLLPTEAI
PLLRAWRGEHVRNAEMVIRATGQPPRSVLCNADPVVGDNGTALGAVCVMHDITQLKDASAALAGERARLQALVDASQDVA
IMAFDPQGRLELFNPGAERLLGYSADEVLGTCPAQFHLPAELERHMATLAVAPFSYATLAAAAAGDVLAEELWTLVRKDG
DLRRVRLCFNVIHDAQQGLAGYLAMAIDVTAELQAQAAAQLAAERFTGAFETAPQGMAIVSLEGEWCDVNPALCGILGYA
REQLLRTTFQQITHPDDLEMDLQLVQDLVDGKRASYSLAKRYISHQGAVIWAQLSVSLVRDSSGAPVHFVSQIQDVTERH
VAAERLAESEARLRAISDATPTLVAQFDAGQRYLFANKAHRAWLGMEPASLVGRHITHVLGEDLSAAARAALVQAVAGQR
ASFEHVLHGGTNPRDVEVSLVPEMHGTATQAQGFFLMAHDVTAHKTLHRLMHQRATRDALTGLPNRHAWSEALQVAMTQA
HQQQLAVAVMFLDLDGFKRINDIYSHRAGDAVLVAFGHCLQRAAGERYLVARLAGDEFVVLLDALQDPQAECATMADRIR
ALAAEGAMFGDQHLPIQPSIGVAWQHGAQAEAASLMHAADEAMYAAKRARRPAEQAVAAVSVVGCWCKPVRCC

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=113, Percent_Identity=48.6725663716814, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI87081977, Length=157, Percent_Identity=33.7579617834395, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081881, Length=216, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787802, Length=200, Percent_Identity=31, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1787541, Length=193, Percent_Identity=30.5699481865285, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1786584, Length=170, Percent_Identity=27.0588235294118, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI145693134, Length=207, Percent_Identity=26.5700483091787, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1788956, Length=166, Percent_Identity=34.3373493975904, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=31.2883435582822, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787262, Length=181, Percent_Identity=29.2817679558011, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 94769; Mature: 94638

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLLPPVPIPVDDALRVDAVRRLGVLDTEAEAEFDDIAWLAAHVTGAPVALVSLLDADR
CEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
QWFKARCGSDLEGTPRSASFCSHAIMGTELMEVPDAEADPRFVNNPLVVGAPGVRSYVGV
HHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEEEECCCHHHHCCC
PLIGREGYAYGTLCTLSTRPRVLDEQQKQALIRLARQAAKQLEARRDRLEAQAQRQTLSM
CEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLEAMPDGVVACGTDGLLREFNHAARQWHGTDPRLLPPEQWALHFDLYTADGTHLLPTEA
HHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCEECCHHH
IPLLRAWRGEHVRNAEMVIRATGQPPRSVLCNADPVVGDNGTALGAVCVMHDITQLKDAS
HHHHHHHCCCCCCCCEEEEEECCCCCHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AALAGERARLQALVDASQDVAIMAFDPQGRLELFNPGAERLLGYSADEVLGTCPAQFHLP
HHHHCHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCHHHHHCCCHHHHHHCCCCCCCCC
AELERHMATLAVAPFSYATLAAAAAGDVLAEELWTLVRKDGDLRRVRLCFNVIHDAQQGL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AGYLAMAIDVTAELQAQAAAQLAAERFTGAFETAPQGMAIVSLEGEWCDVNPALCGILGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
AREQLLRTTFQQITHPDDLEMDLQLVQDLVDGKRASYSLAKRYISHQGAVIWAQLSVSLV
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEEEE
RDSSGAPVHFVSQIQDVTERHVAAERLAESEARLRAISDATPTLVAQFDAGQRYLFANKA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCC
HRAWLGMEPASLVGRHITHVLGEDLSAAARAALVQAVAGQRASFEHVLHGGTNPRDVEVS
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEE
LVPEMHGTATQAQGFFLMAHDVTAHKTLHRLMHQRATRDALTGLPNRHAWSEALQVAMTQ
ECCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AHQQQLAVAVMFLDLDGFKRINDIYSHRAGDAVLVAFGHCLQRAAGERYLVARLAGDEFV
HHHHHHHHHHEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCEE
VLLDALQDPQAECATMADRIRALAAEGAMFGDQHLPIQPSIGVAWQHGAQAEAASLMHAA
EEEEHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHH
DEAMYAAKRARRPAEQAVAAVSVVGCWCKPVRCC
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVLLPPVPIPVDDALRVDAVRRLGVLDTEAEAEFDDIAWLAAHVTGAPVALVSLLDADR
EEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
QWFKARCGSDLEGTPRSASFCSHAIMGTELMEVPDAEADPRFVNNPLVVGAPGVRSYVGV
HHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEEEECCCHHHHCCC
PLIGREGYAYGTLCTLSTRPRVLDEQQKQALIRLARQAAKQLEARRDRLEAQAQRQTLSM
CEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLEAMPDGVVACGTDGLLREFNHAARQWHGTDPRLLPPEQWALHFDLYTADGTHLLPTEA
HHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCEECCHHH
IPLLRAWRGEHVRNAEMVIRATGQPPRSVLCNADPVVGDNGTALGAVCVMHDITQLKDAS
HHHHHHHCCCCCCCCEEEEEECCCCCHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AALAGERARLQALVDASQDVAIMAFDPQGRLELFNPGAERLLGYSADEVLGTCPAQFHLP
HHHHCHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCHHHHHCCCHHHHHHCCCCCCCCC
AELERHMATLAVAPFSYATLAAAAAGDVLAEELWTLVRKDGDLRRVRLCFNVIHDAQQGL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AGYLAMAIDVTAELQAQAAAQLAAERFTGAFETAPQGMAIVSLEGEWCDVNPALCGILGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
AREQLLRTTFQQITHPDDLEMDLQLVQDLVDGKRASYSLAKRYISHQGAVIWAQLSVSLV
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEEEE
RDSSGAPVHFVSQIQDVTERHVAAERLAESEARLRAISDATPTLVAQFDAGQRYLFANKA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCC
HRAWLGMEPASLVGRHITHVLGEDLSAAARAALVQAVAGQRASFEHVLHGGTNPRDVEVS
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEE
LVPEMHGTATQAQGFFLMAHDVTAHKTLHRLMHQRATRDALTGLPNRHAWSEALQVAMTQ
ECCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AHQQQLAVAVMFLDLDGFKRINDIYSHRAGDAVLVAFGHCLQRAAGERYLVARLAGDEFV
HHHHHHHHHHEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCEE
VLLDALQDPQAECATMADRIRALAAEGAMFGDQHLPIQPSIGVAWQHGAQAEAASLMHAA
EEEEHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHH
DEAMYAAKRARRPAEQAVAAVSVVGCWCKPVRCC
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]