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The map label for this gene is 84625316

Identifier: 84625316

GI number: 84625316

Start: 4136063

End: 4137427

Strand: Reverse

Name: 84625316

Synonym: XOO_3659

Alternate gene names: NA

Gene position: 4137427-4136063 (Counterclockwise)

Preceding gene: 84625318

Following gene: 84625314

Centisome position: 83.75

GC content: 65.13

Gene sequence:

>1365_bases
TTGTCGAGCCCCAGCCACGTTGCCGAAACGCCGATCACCGAATGCGCGGAGCTGGTCCAGGTGCTGGCCTCTGGCGAGAA
GCCGAGTGCGGACTGGCGGATCGGCACCGAGCACGAAAAGTTCGGCTTCCAGCTCGACGACCTGCGCGCGCCCACCTTCG
AAGGCGCACGCGGCATCGAGGCCTTGCTGACCGGGTTGACCCGTTTCGGCTGGGAGCCAGTGCAGGAAAACGGCAACACC
ATCGCGCTGCTGCGCGACGGCGCGTCTGTGACGCTGGAGCCGGCCGGGCAGCTGGAGCTCTCCGGCGCGGCAGTGGAAAC
CCTGCACCACACCTGCGTGGAAACCGGCACCCATCTGGACGAAGTGGCGCAAGTCGCCGGCGAGTTGCAGCTGGGGTTCC
TGGGCATGGGCTTCCAGCCCAAGTGGCGTCGCGACCAGATGCCGTGGATGCCCAAGGGCCGCTACCAGATCATGAAGAAC
TACATGCCCAAGGTCGGCGCGCTCGGCCTGGACATGATGACGCGCACCTGCACGGTGCAGGTGAATCTGGATTACGCCAC
CGAAGCGGACATGGTGAAGAAGTTCCGCGTGTCGCTGGCGTTGCAGCCGATCGCCACCGCGTTGTTCGCCGATTCGCCGT
TCACCGAAGGCAAGCCCAACGGCTACCTGAGCTACCGCTCGCACATCTGGACCGACACCGACGCCGACCGTACCGGCATG
CTGGATTTCGTGTTCGAAGACGGCTTCGGCTACGAGCGCTACGTCGATTACCTGCTCGATGTGCCGATGTATTTTTCCTA
CCGCGATGGTGTGTATCACGACGCCAGCGGGCAGAGCTTCCGCGACTTCATGCAGGGCAAACTGCCGGCGCTGCCGGGCG
CGCTGCCGACGCTGCGCGACTGGTCGGACCACATGACCACCGCGTTTCCGGAAGTGCGCTTGAAGAAGTATCTGGAAATG
CGCGGCGCCGATGCCGGCCCGTGGGATCGTCTGTGCGCGTTGTCGGCGTTCTGGGTGGGCCTGCTGTACGACCAGACCGC
GTTGGATGCGGCCTGGGACCTGGTCAAGGATTTCAGTCCGACCGAGCGGCACGCGCTGCGCGATGGCGTGCCCAAGCACG
CGTTGGGCTTGCCGTTCCGCAATGGCACGGCCCGCGATCTGGCAGTGGACGCGGTCGACATCGCCCGCGAAGGCCTGCGT
CGCCGCGCACGCCTGAATCGAGATGGGCATGACGAAACCGGCTTTCTGGATGTGATCGCCGAGATTGCCGAAAGCGGCGT
GACCGCGGCCGAACGCAAGCTGGCGCTGTATCACGGCGCATGGAACGGCGATATCGACCGCGTGTTCCGCGAGTTCGCTT
ACTGA

Upstream 100 bases:

>100_bases
ATCGATTGCGATATGGGCTTGGCGCCGGTCAGGCTATAGTGCGGCCCTTGCGAGGGCGGTACCCGTCCCAGATCGCTCAC
CCTTACCTGCGAGCCTGCCC

Downstream 100 bases:

>100_bases
GCATCCGTCGACAGTCGCCAGCGCGCGCTGGCGCCGGCACACGTCGGTCGTCAGCGATTGCGTGCGGGTGCCGCTGCAGT
CGCATCAGCTGATGCAGTCA

Product: glutamate-cysteine ligase precursor

Products: NA

Alternate protein names: Glutamate/Cysteine Ligase; Gamma-Glutamylcysteine Synthetase; Glutamate/Cysteine Ligase Family Protein; Glutamate-Cysteine Ligase GshA; Glutamylcysteine Synthetase; Glutamate-Cysteine Ligase Family 2 Protein; Glutamate-Cysteine Ligase Protein; Glutathione Synthetase; Glutamate-Cysteine Ligase Gsha; Glutamate-Cysteine Ligase Protein; Glutamate-Cysteine Ligase Family Protein; Glutamate Cystein Ligase Protein; Glutamate-Cysteine Ligase GSHA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSSPSHVAETPITECAELVQVLASGEKPSADWRIGTEHEKFGFQLDDLRAPTFEGARGIEALLTGLTRFGWEPVQENGNT
IALLRDGASVTLEPAGQLELSGAAVETLHHTCVETGTHLDEVAQVAGELQLGFLGMGFQPKWRRDQMPWMPKGRYQIMKN
YMPKVGALGLDMMTRTCTVQVNLDYATEADMVKKFRVSLALQPIATALFADSPFTEGKPNGYLSYRSHIWTDTDADRTGM
LDFVFEDGFGYERYVDYLLDVPMYFSYRDGVYHDASGQSFRDFMQGKLPALPGALPTLRDWSDHMTTAFPEVRLKKYLEM
RGADAGPWDRLCALSAFWVGLLYDQTALDAAWDLVKDFSPTERHALRDGVPKHALGLPFRNGTARDLAVDAVDIAREGLR
RRARLNRDGHDETGFLDVIAEIAESGVTAAERKLALYHGAWNGDIDRVFREFAY

Sequences:

>Translated_454_residues
MSSPSHVAETPITECAELVQVLASGEKPSADWRIGTEHEKFGFQLDDLRAPTFEGARGIEALLTGLTRFGWEPVQENGNT
IALLRDGASVTLEPAGQLELSGAAVETLHHTCVETGTHLDEVAQVAGELQLGFLGMGFQPKWRRDQMPWMPKGRYQIMKN
YMPKVGALGLDMMTRTCTVQVNLDYATEADMVKKFRVSLALQPIATALFADSPFTEGKPNGYLSYRSHIWTDTDADRTGM
LDFVFEDGFGYERYVDYLLDVPMYFSYRDGVYHDASGQSFRDFMQGKLPALPGALPTLRDWSDHMTTAFPEVRLKKYLEM
RGADAGPWDRLCALSAFWVGLLYDQTALDAAWDLVKDFSPTERHALRDGVPKHALGLPFRNGTARDLAVDAVDIAREGLR
RRARLNRDGHDETGFLDVIAEIAESGVTAAERKLALYHGAWNGDIDRVFREFAY
>Mature_453_residues
SSPSHVAETPITECAELVQVLASGEKPSADWRIGTEHEKFGFQLDDLRAPTFEGARGIEALLTGLTRFGWEPVQENGNTI
ALLRDGASVTLEPAGQLELSGAAVETLHHTCVETGTHLDEVAQVAGELQLGFLGMGFQPKWRRDQMPWMPKGRYQIMKNY
MPKVGALGLDMMTRTCTVQVNLDYATEADMVKKFRVSLALQPIATALFADSPFTEGKPNGYLSYRSHIWTDTDADRTGML
DFVFEDGFGYERYVDYLLDVPMYFSYRDGVYHDASGQSFRDFMQGKLPALPGALPTLRDWSDHMTTAFPEVRLKKYLEMR
GADAGPWDRLCALSAFWVGLLYDQTALDAAWDLVKDFSPTERHALRDGVPKHALGLPFRNGTARDLAVDAVDIAREGLRR
RARLNRDGHDETGFLDVIAEIAESGVTAAERKLALYHGAWNGDIDRVFREFAY

Specific function: Unknown

COG id: COG3572

COG function: function code H; Gamma-glutamylcysteine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50703; Mature: 50572

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPSHVAETPITECAELVQVLASGEKPSADWRIGTEHEKFGFQLDDLRAPTFEGARGIE
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCHHHHCCCHHHCCCCCCCCHHHHH
ALLTGLTRFGWEPVQENGNTIALLRDGASVTLEPAGQLELSGAAVETLHHTCVETGTHLD
HHHHHHHHHCCCHHHCCCCEEEEEECCCEEEECCCCCEEECHHHHHHHHHHHHHCCCCHH
EVAQVAGELQLGFLGMGFQPKWRRDQMPWMPKGRYQIMKNYMPKVGALGLDMMTRTCTVQ
HHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCHHHHCEEEEEE
VNLDYATEADMVKKFRVSLALQPIATALFADSPFTEGKPNGYLSYRSHIWTDTDADRTGM
EEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
LDFVFEDGFGYERYVDYLLDVPMYFSYRDGVYHDASGQSFRDFMQGKLPALPGALPTLRD
EEEEEECCCCHHHHHHHHHCCCCEEEECCCCEECCCCHHHHHHHCCCCCCCCCCCCCHHH
WSDHMTTAFPEVRLKKYLEMRGADAGPWDRLCALSAFWVGLLYDQTALDAAWDLVKDFSP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TERHALRDGVPKHALGLPFRNGTARDLAVDAVDIAREGLRRRARLNRDGHDETGFLDVIA
HHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
EIAESGVTAAERKLALYHGAWNGDIDRVFREFAY
HHHHCCCHHHHHEEEEEECCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SSPSHVAETPITECAELVQVLASGEKPSADWRIGTEHEKFGFQLDDLRAPTFEGARGIE
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCHHHHCCCHHHCCCCCCCCHHHHH
ALLTGLTRFGWEPVQENGNTIALLRDGASVTLEPAGQLELSGAAVETLHHTCVETGTHLD
HHHHHHHHHCCCHHHCCCCEEEEEECCCEEEECCCCCEEECHHHHHHHHHHHHHCCCCHH
EVAQVAGELQLGFLGMGFQPKWRRDQMPWMPKGRYQIMKNYMPKVGALGLDMMTRTCTVQ
HHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCHHHHCEEEEEE
VNLDYATEADMVKKFRVSLALQPIATALFADSPFTEGKPNGYLSYRSHIWTDTDADRTGM
EEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
LDFVFEDGFGYERYVDYLLDVPMYFSYRDGVYHDASGQSFRDFMQGKLPALPGALPTLRD
EEEEEECCCCHHHHHHHHHCCCCEEEECCCCEECCCCHHHHHHHCCCCCCCCCCCCCHHH
WSDHMTTAFPEVRLKKYLEMRGADAGPWDRLCALSAFWVGLLYDQTALDAAWDLVKDFSP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TERHALRDGVPKHALGLPFRNGTARDLAVDAVDIAREGLRRRARLNRDGHDETGFLDVIA
HHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
EIAESGVTAAERKLALYHGAWNGDIDRVFREFAY
HHHHCCCHHHHHEEEEEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA