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The map label for this gene is ribH [H]

Identifier: 84625288

GI number: 84625288

Start: 4107886

End: 4108350

Strand: Reverse

Name: ribH [H]

Synonym: XOO_3631

Alternate gene names: 84625288

Gene position: 4108350-4107886 (Counterclockwise)

Preceding gene: 84625289

Following gene: 84625287

Centisome position: 83.16

GC content: 67.1

Gene sequence:

>465_bases
ATGACCCACTACGAAGGCGATCTTCGCCCCCCCACCGCGCGCTTTGCGATCATCGCCAGCCGCTGGAACGCCCGCATCAC
CGACGTGCTGGTTGCCGGCGCGCGCCAGAGCCTGGCCGGCAACGGCATTGGCGAAGACGCCATCGACGTGATCCGCGTGC
CCGGCGCCTGGGAAATTCCGGTCGCCGCCAATCGCGTGGCGCAGTCCGGCCAGCATGGCGCGATCATCGCGCTGGGCTGC
GTGATCCGTGGCGATACCCGCCATTACGAACACGTGGCCGACCTGTGCGCCGAAGGCCTGATGAGCGTGCAACTGCAGAC
CGGCGTGCCGGTGCTCAACGGCGTGCTGGCAGTTGAACGCGTGGAAGATGCCGAAGCGCGTGCCGGCGGCAGCCACGGCA
ACAAGGGCGAGGAGTGCGCGCTTGCAGCGCTGGAGCTGGTGAATTTGATGGAGTTGTTGCCATGA

Upstream 100 bases:

>100_bases
ACATGGCCGAGTCTGCTTTGGTGGACCTGGCGTGCACGCGTCGGCCAGGCCTGGCCCCGGCAGCTGTTAAACTTCTCGCC
CCCTTGAGTTGCCGACCCGC

Downstream 100 bases:

>100_bases
GCAAGCCCGGTGGACACCCGCGCCACGGCCGTCGCGACGGCATCGACCCGGTGCTGCGTTCGCGCGCACGTCGGCGTGCC
TTGCAGGCAGTGTATGCGTG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTHYEGDLRPPTARFAIIASRWNARITDVLVAGARQSLAGNGIGEDAIDVIRVPGAWEIPVAANRVAQSGQHGAIIALGC
VIRGDTRHYEHVADLCAEGLMSVQLQTGVPVLNGVLAVERVEDAEARAGGSHGNKGEECALAALELVNLMELLP

Sequences:

>Translated_154_residues
MTHYEGDLRPPTARFAIIASRWNARITDVLVAGARQSLAGNGIGEDAIDVIRVPGAWEIPVAANRVAQSGQHGAIIALGC
VIRGDTRHYEHVADLCAEGLMSVQLQTGVPVLNGVLAVERVEDAEARAGGSHGNKGEECALAALELVNLMELLP
>Mature_153_residues
THYEGDLRPPTARFAIIASRWNARITDVLVAGARQSLAGNGIGEDAIDVIRVPGAWEIPVAANRVAQSGQHGAIIALGCV
IRGDTRHYEHVADLCAEGLMSVQLQTGVPVLNGVLAVERVEDAEARAGGSHGNKGEECALAALELVNLMELLP

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=152, Percent_Identity=44.078947368421, Blast_Score=121, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324429, Length=142, Percent_Identity=36.6197183098592, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16224; Mature: 16092

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHYEGDLRPPTARFAIIASRWNARITDVLVAGARQSLAGNGIGEDAIDVIRVPGAWEIP
CCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHEEECCCCCCCC
VAANRVAQSGQHGAIIALGCVIRGDTRHYEHVADLCAEGLMSVQLQTGVPVLNGVLAVER
HHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHH
VEDAEARAGGSHGNKGEECALAALELVNLMELLP
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
THYEGDLRPPTARFAIIASRWNARITDVLVAGARQSLAGNGIGEDAIDVIRVPGAWEIP
CCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHEEECCCCCCCC
VAANRVAQSGQHGAIIALGCVIRGDTRHYEHVADLCAEGLMSVQLQTGVPVLNGVLAVER
HHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHH
VEDAEARAGGSHGNKGEECALAALELVNLMELLP
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]