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The map label for this gene is alkB [C]

Identifier: 84622387

GI number: 84622387

Start: 787809

End: 788417

Strand: Direct

Name: alkB [C]

Synonym: XOO_0730

Alternate gene names: 84622387

Gene position: 787809-788417 (Clockwise)

Preceding gene: 84622384

Following gene: 84622392

Centisome position: 15.95

GC content: 65.52

Gene sequence:

>609_bases
ATGAAGATTCGGGTGGCATTGCCGGGGGCGGAGATCGACTGGTGGCGCGGTTGGCTGCCGCACGCGCAGGCCGATGCGCT
GATGCAGGCGCTGCTTGTGCAGGCGCACTGGCAGCTGCACCGCATCCGAATGTTCGGGCGCATGGTGGATTCGCCGCGCT
TGAGCAGTTGGATCGGCGATCCGGAGGCGAGTTATCGCTACTCGGGCACACGCTTCTCGCCACAGCCGTGGCTGGAGGTG
CTGCAGCCAGTGCGTCTGCGCCTGGAGGACGAGACCGGTCACCGGTTCAACAGCGTGCTGATTAACCGCTACCGCAGTGG
CAGTGATGCGATGGGCTGGCACAGCGACGACGAGCCGGAACTGGGCGCGCAGCCATTGATTGCCTCAGTGAGCCTGGGCG
CGAGGCGACGTTTCGCATTCAAGCATCGCGACGATGCGTCGGTGAAGCAGGCGTTGGAACTGGGCCACGGCGATCTGTTG
TTGATGGGCGGCCAGACCCAGCGCCACTACAGACACGCCCTGCCGCGCACCGCGAAGCCGGTTGGCGAGCGCATCAATCT
GACCTTTCGTCAGGTCGCGGGTGCGCGTGTGCCAGCCATACGCGGCTAG

Upstream 100 bases:

>100_bases
GGCTCGATGGCTGGTGTCCATTTTCCGGGATTGCATGTGACGGCGGCAAATCGGGTCGATTCATCCGCGCCATGCGGGGC
TGCGTGCTAGCGTTGCCCGC

Downstream 100 bases:

>100_bases
CAACATGTAGCGCGCTCGCCTGGGCGGTAAGCCCGGTGGGCGTGTCGGCCGCAGCTTGCGTGGGCGCAATCAGCAGTCCA
GGTCAAACGATGAGTGGATC

Product: DNA repair system specific for alkylated DNA

Products: NA

Alternate protein names: 2OG-Fe(II) Oxygenase; DNA-N1-Methyladenine Dioxygenase; DNA Repair System Specific For Alkylated DNA; 2OG-Fe(II) Oxygenase Superfamily Protein; 2OG-Fe(II) Oxygenase Family Oxidoreductase; Oxidoreductase 2OG-Fe(II) Oxygenase Family; Alkylated DNA Repair Protein-Like Protein; Oxidoreductase 2OG-Fe(II) Oxygenase Family Protein; CRISPR-Associated Family Protein; DNA Repair System Specific For Alkylated DNA Protein; 2OG-Fe(II) Oxygenase Family Protein; LOW QUALITY PROTEIN Alkylated DNA Repair Protein; DNA Repair System Protein; Alkylated DNA Repair Protein AlkB

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKIRVALPGAEIDWWRGWLPHAQADALMQALLVQAHWQLHRIRMFGRMVDSPRLSSWIGDPEASYRYSGTRFSPQPWLEV
LQPVRLRLEDETGHRFNSVLINRYRSGSDAMGWHSDDEPELGAQPLIASVSLGARRRFAFKHRDDASVKQALELGHGDLL
LMGGQTQRHYRHALPRTAKPVGERINLTFRQVAGARVPAIRG

Sequences:

>Translated_202_residues
MKIRVALPGAEIDWWRGWLPHAQADALMQALLVQAHWQLHRIRMFGRMVDSPRLSSWIGDPEASYRYSGTRFSPQPWLEV
LQPVRLRLEDETGHRFNSVLINRYRSGSDAMGWHSDDEPELGAQPLIASVSLGARRRFAFKHRDDASVKQALELGHGDLL
LMGGQTQRHYRHALPRTAKPVGERINLTFRQVAGARVPAIRG
>Mature_202_residues
MKIRVALPGAEIDWWRGWLPHAQADALMQALLVQAHWQLHRIRMFGRMVDSPRLSSWIGDPEASYRYSGTRFSPQPWLEV
LQPVRLRLEDETGHRFNSVLINRYRSGSDAMGWHSDDEPELGAQPLIASVSLGARRRFAFKHRDDASVKQALELGHGDLL
LMGGQTQRHYRHALPRTAKPVGERINLTFRQVAGARVPAIRG

Specific function: Probably Involved In The Repair Of Alkylated DNA. Provides Extensive Resistance To Alkylating Agents Such As Mms And Dms (Sn2 Agents), But Not To Mmng And Mnu (Sn1 Agents). [C]

COG id: COG3145

COG function: function code L; Alkylated DNA repair protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI224451107, Length=181, Percent_Identity=40.3314917127072, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI48717226, Length=181, Percent_Identity=40.3314917127072, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI224451103, Length=181, Percent_Identity=40.3314917127072, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI21040275, Length=185, Percent_Identity=37.8378378378378, Blast_Score=120, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 23000; Mature: 23000

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRVALPGAEIDWWRGWLPHAQADALMQALLVQAHWQLHRIRMFGRMVDSPRLSSWIGD
CEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
PEASYRYSGTRFSPQPWLEVLQPVRLRLEDETGHRFNSVLINRYRSGSDAMGWHSDDEPE
CCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
LGAQPLIASVSLGARRRFAFKHRDDASVKQALELGHGDLLLMGGQTQRHYRHALPRTAKP
CCCCCHHHHHHHCHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCCC
VGERINLTFRQVAGARVPAIRG
CHHHHCHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKIRVALPGAEIDWWRGWLPHAQADALMQALLVQAHWQLHRIRMFGRMVDSPRLSSWIGD
CEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
PEASYRYSGTRFSPQPWLEVLQPVRLRLEDETGHRFNSVLINRYRSGSDAMGWHSDDEPE
CCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
LGAQPLIASVSLGARRRFAFKHRDDASVKQALELGHGDLLLMGGQTQRHYRHALPRTAKP
CCCCCHHHHHHHCHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCCC
VGERINLTFRQVAGARVPAIRG
CHHHHCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA