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The map label for this gene is lpsI [H]

Identifier: 84622383

GI number: 84622383

Start: 782542

End: 783273

Strand: Direct

Name: lpsI [H]

Synonym: XOO_0726

Alternate gene names: 84622383

Gene position: 782542-783273 (Clockwise)

Preceding gene: 84622380

Following gene: 84622384

Centisome position: 15.84

GC content: 61.07

Gene sequence:

>732_bases
ATGCGCAATGAAGTAAGCGGTGCGGCAAGCGGCAAACGCTATGCCGATGCCAAGACAGCGCTGGATGGGGTACTGGCCGA
TGGTCAGACCCTGGCAGTGGGCGGCTTTGGGTTGTGTGGCATTCCGGAGGCACTGATTGCAGCCCTACGCGACAGTGGGG
TCGCCGGGTTGACCGTGATCTCCAACAACGCTGGCGTCGACGGTTTCGGGCTTGGTCAATTATTGGCTACCCGACAGATC
CGCAAGATGATTTCGTCCTATGTGGGCGAAAACAAGGAATTCGAACGCCAATACCTGGCAGGCGAACTTGAGCTGGAGTT
CAATCCGCAAGGCACCCTGGCCGAGCGTTTGCGCGCGGGCGGGGCGGGAATTGCTGCGTTTTATACGGCCACCGGCTACG
GCACGATCGTGGCCGAGGGCAAGGAAACGCGCGAATTCGACGGCAAGCACTACGTGCTGGAAACCGCACTGCACGCCGAT
GTGGCGCTGGTGAAGGCATGGCGCGCCGATACCGCGGGCAACCTGGTGTTCCGCAAGACGGCACGCAATTTCAATCCGGC
CTGCGCCATGGCGGGTCGCGTGTGCATTGCCGAGGTGGAGGAGATCGTTGAGCTGGGCGTTATCGACCCGGATCAGGTGC
ATCTGCCCGGTATTTACGTGGACCGCCTGGTGCTCAATGCCACGCCGGAAAAACGCATCGAACAGCGCACCGTGCGCGAA
GGACAGCAGTAA

Upstream 100 bases:

>100_bases
AGCGGCTGCGCCGTGTCTTGGGTGTGGCGAAATTGCGACCGGGGGCAGGGAACAGTCAGCGGATAGAATGGGCGCTTCAC
ATCGGCGGGTGAGGGCGGTG

Downstream 100 bases:

>100_bases
TGGCCTGGACCAGAGACCACATGGCCGCACGCGCGGCACGCGAACTGACCGATGGCGCTTACGTCAACCTGGGTATCGGC
TTGCCGACGTTGGTTGCCAA

Product: IpsJ protein

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRNEVSGAASGKRYADAKTALDGVLADGQTLAVGGFGLCGIPEALIAALRDSGVAGLTVISNNAGVDGFGLGQLLATRQI
RKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAGGAGIAAFYTATGYGTIVAEGKETREFDGKHYVLETALHAD
VALVKAWRADTAGNLVFRKTARNFNPACAMAGRVCIAEVEEIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
GQQ

Sequences:

>Translated_243_residues
MRNEVSGAASGKRYADAKTALDGVLADGQTLAVGGFGLCGIPEALIAALRDSGVAGLTVISNNAGVDGFGLGQLLATRQI
RKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAGGAGIAAFYTATGYGTIVAEGKETREFDGKHYVLETALHAD
VALVKAWRADTAGNLVFRKTARNFNPACAMAGRVCIAEVEEIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
GQQ
>Mature_243_residues
MRNEVSGAASGKRYADAKTALDGVLADGQTLAVGGFGLCGIPEALIAALRDSGVAGLTVISNNAGVDGFGLGQLLATRQI
RKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAGGAGIAAFYTATGYGTIVAEGKETREFDGKHYVLETALHAD
VALVKAWRADTAGNLVFRKTARNFNPACAMAGRVCIAEVEEIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
GQQ

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=56.2753036437247, Blast_Score=283, Evalue=1e-76,
Organism=Homo sapiens, GI11545841, Length=245, Percent_Identity=55.1020408163265, Blast_Score=248, Evalue=4e-66,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=44.1176470588235, Blast_Score=189, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17531517, Length=251, Percent_Identity=55.3784860557769, Blast_Score=267, Evalue=4e-72,
Organism=Drosophila melanogaster, GI21358325, Length=251, Percent_Identity=49.402390438247, Blast_Score=246, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24655794, Length=251, Percent_Identity=49.402390438247, Blast_Score=246, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25940; Mature: 25940

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNEVSGAASGKRYADAKTALDGVLADGQTLAVGGFGLCGIPEALIAALRDSGVAGLTVI
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEE
SNNAGVDGFGLGQLLATRQIRKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAG
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCC
GAGIAAFYTATGYGTIVAEGKETREFDGKHYVLETALHADVALVKAWRADTAGNLVFRKT
CCCEEEEEEECCCEEEEECCCCHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEC
ARNFNPACAMAGRVCIAEVEEIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEHHHEECCCCHHHHHHHHHHC
GQQ
CCC
>Mature Secondary Structure
MRNEVSGAASGKRYADAKTALDGVLADGQTLAVGGFGLCGIPEALIAALRDSGVAGLTVI
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEE
SNNAGVDGFGLGQLLATRQIRKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAG
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCC
GAGIAAFYTATGYGTIVAEGKETREFDGKHYVLETALHADVALVKAWRADTAGNLVFRKT
CCCEEEEEEECCCEEEEECCCCHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEC
ARNFNPACAMAGRVCIAEVEEIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEHHHEECCCCHHHHHHHHHHC
GQQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]