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The map label for this gene is dinB [H]

Identifier: 84622350

GI number: 84622350

Start: 746721

End: 747800

Strand: Direct

Name: dinB [H]

Synonym: XOO_0693

Alternate gene names: 84622350

Gene position: 746721-747800 (Clockwise)

Preceding gene: 84622347

Following gene: 84622351

Centisome position: 15.12

GC content: 64.07

Gene sequence:

>1080_bases
ATGCGCAAGATCGTGCACGTGGACATGGATGCGTTCTACGCGTCCGTGGAGCAACGTGACGACCCTGGCCTGCGCGGCAA
GCCAGTGGTGGTGGCTTGGCGCGGTGCGCGCTCGGTGGTGTGCGCAGCCTCCTACGAAGCGCGCACCTTCGGCATTCGCT
CGGCGATGCCAGCCGTGCGCGCAGAGCGTCTGTGCCCGAATGCGATCTTCGTGCCGCCGGATTTTGTGCGCTACAAGGCG
GTATCGCGGCAAGTGCGCGAGATCTTCCACCGGCATACCGATCTGGTCGAGCCGCTGTCGCTGGACGAGGCCTATCTGGA
TGTCACGCAAGCCAAAACCGGCATGCAGCTGGCCACCGAGATCGCGCAGCTGATCCGCACGCAGATTCGCGAAGAAACCG
AGCTCACCGCATCGGCCGGTATCGCGCCGAACAAGTTCCTGGCCAAGATCGCGTCCGATTGGCGCAAGCCCGATGGTCAG
TTCGTGATCGCGCCCAGTCGCATCGACGCATTCTTGCTGCCGCTCAAGGTCAATCGCATTCCCGGCGTGGGCAAGGTGAT
GGATGGCAAGCTGGCGGCACTGGGCATCGTCACCGTGGCCGATCTGCGCCTGCGCCCGTTGGAAGAACTGCAGGCGCATT
TCGGCAGTTTCGGGCAAAGCCTGTACCGCCGCGCGCGCGGCATCGACGAACGCCCGGTCGAGCCGGATCAGGACGTGCAG
TCGGTTTCCTCGGAAGACACCTTCAGCGAAGATCTCGCGCTTGATGCCTTGGATACGCACATCCTGCGCCTGGCCGAAAA
AACCTGGCTGGCCACACGCCGCACCGAGCGTATCGGCCGCACGGTGGTGCTGAAGTTGAAGACCTCCAATTTCCGTATCC
TGACCCGCTCCTGCACGCCTGAGCAGCCGCCTGTGTCGCAGGAGGCGCTGGCACAGATCGCGCTGGCACTGACCCGCCGT
GTGGAGCTGCCTGCGCAGACGCGCTATCGCCTGGTCGGTGTTGGCCTGAGCGGTTTCAGCAATGTCGAAGAAGGCGCTGT
GCAGGGGCAGCTGTTTGGCGAAATTCCCCAGGCCGAGTGA

Upstream 100 bases:

>100_bases
CGCGCTCGTTTTTCGACCGCGCCGTGGTCCATCTCCACTCAAGGCGTGAGACAGCGCTGGCTTATCATGGGTGCAGGCCT
GCGACAGAGAAACCCGCTTG

Downstream 100 bases:

>100_bases
GTGCCATCCACCGGGCATGACGGGCTACATATGTCGCTGACTGTATCGACGCGCTCAGCGAACAATCCAAAGCGCTCCAC
AGTGTGCGCGCTGCATCCGG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRKIVHVDMDAFYASVEQRDDPGLRGKPVVVAWRGARSVVCAASYEARTFGIRSAMPAVRAERLCPNAIFVPPDFVRYKA
VSRQVREIFHRHTDLVEPLSLDEAYLDVTQAKTGMQLATEIAQLIRTQIREETELTASAGIAPNKFLAKIASDWRKPDGQ
FVIAPSRIDAFLLPLKVNRIPGVGKVMDGKLAALGIVTVADLRLRPLEELQAHFGSFGQSLYRRARGIDERPVEPDQDVQ
SVSSEDTFSEDLALDALDTHILRLAEKTWLATRRTERIGRTVVLKLKTSNFRILTRSCTPEQPPVSQEALAQIALALTRR
VELPAQTRYRLVGVGLSGFSNVEEGAVQGQLFGEIPQAE

Sequences:

>Translated_359_residues
MRKIVHVDMDAFYASVEQRDDPGLRGKPVVVAWRGARSVVCAASYEARTFGIRSAMPAVRAERLCPNAIFVPPDFVRYKA
VSRQVREIFHRHTDLVEPLSLDEAYLDVTQAKTGMQLATEIAQLIRTQIREETELTASAGIAPNKFLAKIASDWRKPDGQ
FVIAPSRIDAFLLPLKVNRIPGVGKVMDGKLAALGIVTVADLRLRPLEELQAHFGSFGQSLYRRARGIDERPVEPDQDVQ
SVSSEDTFSEDLALDALDTHILRLAEKTWLATRRTERIGRTVVLKLKTSNFRILTRSCTPEQPPVSQEALAQIALALTRR
VELPAQTRYRLVGVGLSGFSNVEEGAVQGQLFGEIPQAE
>Mature_359_residues
MRKIVHVDMDAFYASVEQRDDPGLRGKPVVVAWRGARSVVCAASYEARTFGIRSAMPAVRAERLCPNAIFVPPDFVRYKA
VSRQVREIFHRHTDLVEPLSLDEAYLDVTQAKTGMQLATEIAQLIRTQIREETELTASAGIAPNKFLAKIASDWRKPDGQ
FVIAPSRIDAFLLPLKVNRIPGVGKVMDGKLAALGIVTVADLRLRPLEELQAHFGSFGQSLYRRARGIDERPVEPDQDVQ
SVSSEDTFSEDLALDALDTHILRLAEKTWLATRRTERIGRTVVLKLKTSNFRILTRSCTPEQPPVSQEALAQIALALTRR
VELPAQTRYRLVGVGLSGFSNVEEGAVQGQLFGEIPQAE

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=380, Percent_Identity=31.3157894736842, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI7706681, Length=381, Percent_Identity=31.2335958005249, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI154350220, Length=357, Percent_Identity=29.6918767507003, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=51.4018691588785, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI5729982, Length=347, Percent_Identity=27.9538904899135, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1786425, Length=253, Percent_Identity=52.1739130434783, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1787432, Length=371, Percent_Identity=28.0323450134771, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193205700, Length=406, Percent_Identity=32.7586206896552, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17537959, Length=239, Percent_Identity=32.6359832635983, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=352, Percent_Identity=31.25, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115534089, Length=132, Percent_Identity=35.6060606060606, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=250, Percent_Identity=26.8, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19923006, Length=298, Percent_Identity=28.8590604026846, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=28.2685512367491, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=28.2685512367491, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24668444, Length=120, Percent_Identity=35, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39879; Mature: 39879

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIVHVDMDAFYASVEQRDDPGLRGKPVVVAWRGARSVVCAASYEARTFGIRSAMPAVR
CCCEEEECHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHH
AERLCPNAIFVPPDFVRYKAVSRQVREIFHRHTDLVEPLSLDEAYLDVTQAKTGMQLATE
HHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
IAQLIRTQIREETELTASAGIAPNKFLAKIASDWRKPDGQFVIAPSRIDAFLLPLKVNRI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEECCC
PGVGKVMDGKLAALGIVTVADLRLRPLEELQAHFGSFGQSLYRRARGIDERPVEPDQDVQ
CCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
SVSSEDTFSEDLALDALDTHILRLAEKTWLATRRTERIGRTVVLKLKTSNFRILTRSCTP
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCC
EQPPVSQEALAQIALALTRRVELPAQTRYRLVGVGLSGFSNVEEGAVQGQLFGEIPQAE
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure
MRKIVHVDMDAFYASVEQRDDPGLRGKPVVVAWRGARSVVCAASYEARTFGIRSAMPAVR
CCCEEEECHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHH
AERLCPNAIFVPPDFVRYKAVSRQVREIFHRHTDLVEPLSLDEAYLDVTQAKTGMQLATE
HHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
IAQLIRTQIREETELTASAGIAPNKFLAKIASDWRKPDGQFVIAPSRIDAFLLPLKVNRI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEECCC
PGVGKVMDGKLAALGIVTVADLRLRPLEELQAHFGSFGQSLYRRARGIDERPVEPDQDVQ
CCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
SVSSEDTFSEDLALDALDTHILRLAEKTWLATRRTERIGRTVVLKLKTSNFRILTRSCTP
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCC
EQPPVSQEALAQIALALTRRVELPAQTRYRLVGVGLSGFSNVEEGAVQGQLFGEIPQAE
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]