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The map label for this gene is nudC [H]

Identifier: 84622148

GI number: 84622148

Start: 537049

End: 537939

Strand: Direct

Name: nudC [H]

Synonym: XOO_0491

Alternate gene names: 84622148

Gene position: 537049-537939 (Clockwise)

Preceding gene: 84622147

Following gene: 84622149

Centisome position: 10.87

GC content: 66.78

Gene sequence:

>891_bases
ATGTCAGGGTCTCTTTTTTCACCGTCCGATGTTGCCTTCACCCACGCGCCGCTTGATCGCGGCGATGTGTTGCGTGACGA
TCCCGACGCCCTGGCGCGTCTGTGGCCACACGGCCGTGTGCTGTTGATCGACGCCAAGGGCGCGGCGCTGGCCGATGCCA
ATGGCCAGCCGTTGTTGCTGGATGGCGCCAAACTGGGAGACGGGCTGGAGGTTGCGATCTTCCTGGGTCTGCGCGATGCA
GTGGGCTGGTTTTGTCTGCCGGCCGACATTGTCCCGGTGCAGGCGCCGCAGCGGATCGATCTGCGCCAGGCCGCTGCCGA
CTGGCCAGCCGAGATCGCTACCGCCTTCGCCTATGCACGCGCCATGTTGCACTGGCAATCGCGCACGCGCTTTTGCGGCG
TCTGTGGCGGTGCGATCGCGTTCCGGCGCGCTGGCTTCATCGCGCACTGCACGCACTGCCAGACCGAGCATTACCCGCGC
GTGGATCCGGCCATTATCGTGGCGGTGAGCGATGGCGCGCGCTTGCTGCTCGGCCGTCAGGCCAGTTGGGCGCCGGGCCG
TTATTCGGTGATTGCCGGGTTTGTTGAACCGGGTGAGTCGCTGGAGCAGACCGTAGCGCGGGAGGTGTTCGAAGAAACCC
GCGTGCATGTGCAGGACTGCCGCTATCTGGGCGCGCAGCCGTGGCCCTTCCCGGGCGCGCTGATGCTGGGCTTCACCGCA
CGTGCCCCAGCGACCGAGGTGCCGCAGGTCACCAGTGAGCTGGAGGACGCGCGTTGGGTCAGCCATGCCGAAGTCAGCGC
TGCGCTGGCCGGCGAGGCCGACATCGGGTTGCCGCCGCGCATCTCCATTGCACGTGCGTTGATTGAGCACTGGCATCGCA
CGCATGGCTGA

Upstream 100 bases:

>100_bases
AGCGCGGGCGGCGCCCGCGTCTGAATACGCAACGCAAGCACGCTCGGTAGAGTGCGTACGATGGTTGCAGGCGCTGCCGA
TTATCGGCAGGCTTGCGCCG

Downstream 100 bases:

>100_bases
GCCTGGGAGGTTGTTGCAGCGTTGCAGCGGTGCTTGCGTCCCCTCGGCTAGACTCGGCTGAGGAGGCCCACCCATGTTCA
CCACCCTGGTAGCCGTCGTC

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSGSLFSPSDVAFTHAPLDRGDVLRDDPDALARLWPHGRVLLIDAKGAALADANGQPLLLDGAKLGDGLEVAIFLGLRDA
VGWFCLPADIVPVQAPQRIDLRQAAADWPAEIATAFAYARAMLHWQSRTRFCGVCGGAIAFRRAGFIAHCTHCQTEHYPR
VDPAIIVAVSDGARLLLGRQASWAPGRYSVIAGFVEPGESLEQTVAREVFEETRVHVQDCRYLGAQPWPFPGALMLGFTA
RAPATEVPQVTSELEDARWVSHAEVSAALAGEADIGLPPRISIARALIEHWHRTHG

Sequences:

>Translated_296_residues
MSGSLFSPSDVAFTHAPLDRGDVLRDDPDALARLWPHGRVLLIDAKGAALADANGQPLLLDGAKLGDGLEVAIFLGLRDA
VGWFCLPADIVPVQAPQRIDLRQAAADWPAEIATAFAYARAMLHWQSRTRFCGVCGGAIAFRRAGFIAHCTHCQTEHYPR
VDPAIIVAVSDGARLLLGRQASWAPGRYSVIAGFVEPGESLEQTVAREVFEETRVHVQDCRYLGAQPWPFPGALMLGFTA
RAPATEVPQVTSELEDARWVSHAEVSAALAGEADIGLPPRISIARALIEHWHRTHG
>Mature_295_residues
SGSLFSPSDVAFTHAPLDRGDVLRDDPDALARLWPHGRVLLIDAKGAALADANGQPLLLDGAKLGDGLEVAIFLGLRDAV
GWFCLPADIVPVQAPQRIDLRQAAADWPAEIATAFAYARAMLHWQSRTRFCGVCGGAIAFRRAGFIAHCTHCQTEHYPRV
DPAIIVAVSDGARLLLGRQASWAPGRYSVIAGFVEPGESLEQTVAREVFEETRVHVQDCRYLGAQPWPFPGALMLGFTAR
APATEVPQVTSELEDARWVSHAEVSAALAGEADIGLPPRISIARALIEHWHRTHG

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=195, Percent_Identity=40, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI50593112, Length=206, Percent_Identity=37.8640776699029, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI48994995, Length=160, Percent_Identity=37.5, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI212645999, Length=160, Percent_Identity=33.125, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71986510, Length=160, Percent_Identity=33.125, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321371, Length=211, Percent_Identity=31.2796208530806, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 32001; Mature: 31869

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSLFSPSDVAFTHAPLDRGDVLRDDPDALARLWPHGRVLLIDAKGAALADANGQPLLL
CCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCEEECCCCCEEEE
DGAKLGDGLEVAIFLGLRDAVGWFCLPADIVPVQAPQRIDLRQAAADWPAEIATAFAYAR
ECCCCCCCCEEEEEEECHHHCCEEEECCCCEECCCCCCCCHHHHHCCCHHHHHHHHHHHH
AMLHWQSRTRFCGVCGGAIAFRRAGFIAHCTHCQTEHYPRVDPAIIVAVSDGARLLLGRQ
HHHHHHHCCCEEHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEEECCCCEEEEECC
ASWAPGRYSVIAGFVEPGESLEQTVAREVFEETRVHVQDCRYLGAQPWPFPGALMLGFTA
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEC
RAPATEVPQVTSELEDARWVSHAEVSAALAGEADIGLPPRISIARALIEHWHRTHG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGSLFSPSDVAFTHAPLDRGDVLRDDPDALARLWPHGRVLLIDAKGAALADANGQPLLL
CCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCEEECCCCCEEEE
DGAKLGDGLEVAIFLGLRDAVGWFCLPADIVPVQAPQRIDLRQAAADWPAEIATAFAYAR
ECCCCCCCCEEEEEEECHHHCCEEEECCCCEECCCCCCCCHHHHHCCCHHHHHHHHHHHH
AMLHWQSRTRFCGVCGGAIAFRRAGFIAHCTHCQTEHYPRVDPAIIVAVSDGARLLLGRQ
HHHHHHHCCCEEHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEEECCCCEEEEECC
ASWAPGRYSVIAGFVEPGESLEQTVAREVFEETRVHVQDCRYLGAQPWPFPGALMLGFTA
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEC
RAPATEVPQVTSELEDARWVSHAEVSAALAGEADIGLPPRISIARALIEHWHRTHG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]