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The map label for this gene is trpS [H]

Identifier: 84622058

GI number: 84622058

Start: 432151

End: 433440

Strand: Direct

Name: trpS [H]

Synonym: XOO_0401

Alternate gene names: 84622058

Gene position: 432151-433440 (Clockwise)

Preceding gene: 84622057

Following gene: 84622059

Centisome position: 8.75

GC content: 62.33

Gene sequence:

>1290_bases
ATGACCACTCGTGTCCTTACCGGCATCACCACTTCCGGCACCCCGCATCTGGGAAATTACGTCGGCGCGATCCGCCCCGC
CATCCAGGCCAGCGCGGGCGCCGATACCGAGAGCTTCTATTTTCTGGCTGACCTGCATAGCCTGATCAAGGCACAGGACC
CGGCGCGCACGCAGCGCTCGACGCTGGAAATTGCCGCCACCTGGCTGGCCTGCGGTCTGGATCCGGACAAGGTGTGGTTC
TACCGGCAGTCCGACGTGCCCGAGACTACCGAGTTGATGTGGCTGCTGACCTGCGTGGCCGGCAAGGGCATCCTCAATCG
CGCGCATGCCTACAAGGCCGCGGTGGACAAGAACTGCGCCGACGGTGAGGACGAAGATGCCGGCGTCACCGCAGGCTTGT
TCATGTATCCGGTGCTGATGGCGGCTGACATCCTGATCTTCAACGCGCACAAGGTGCCGGTGGGGCGCGATCAGATTCAG
CACATCGAAATGGCACGCGATTTTGCGCAGCGCTTCAATCATGTCTATGGGCGCGAGTTTTTCACCTTGCCCGAAGGGGT
GATCGACGAGCAGGTCTCTACCTTGCCGGGGCTGGACGGCCGCAAGATGAGCAAGAGCTACAGCAATACGATTCCGCTGT
TTGCACCGCGCGAGGAGTTGCGCAAGCTGGTGTTTTCCATCCTCACCGATTCGCGTGCGCCGGGTGAGGCGAAGGACACG
CAGGGGTCGGCCTTATTCCAGCTGTATCAGGCCTTCGCTGCGCCGCAGGAGTCTGCGGCATTTGCGCAGGCATTTGCCGA
CGGTATTAGCTGGGGCGATGCGAAGCAGCAGTTGTTCGACCGGATCGATCAGGACATTGCACCGCTGCGCGCACGCTACG
AAGCATTGATGGCAGAGCCGGCCAAGATCGAAGCGATGCTGCGCGCTGGCGGCGCACGTCTGCGCGCACGCTACGCCACC
CCGCTGCTGGCCGAGCTGCGCGATGCAGTAGGCCTGCGCGATCTGTCCCGTCAGGCTGGTGCAGCGGTGAGCGCGGTCGG
CGAGAGGATCGCGCTGCCGGTATTCAAGCAATACCGTGAAAGCGATGGCCAGTTCTATTTCAAGTTGAACGACGGCGCAG
GTACGTTGCTGTTGCAGAGCGATGGCTTCGCATCGCCACGCGATGCCGGGCAATTGATCGCACGGTTGAAACAGGCAGCG
CAGGCGAGCGATTTGCAACTGCCGGGCGTGCATGCGCACATGGATGCGGACGTGATTCTTGCGGCGATGCACGCATTGCG
CGAGGCATGA

Upstream 100 bases:

>100_bases
TCTGCGTTTGTGCGTCTAAAACCTGCCTTCGACCAGGGGCCGGCAATGGCGGGCGTGCGGAACCGCTAAACTTGGGGGCT
GATTCCCTGGCATTACGCAG

Downstream 100 bases:

>100_bases
TCGACATGACGCTGCAGGCGTCGCTGTTCGCCATGGCTAGCCGCATTCTGGGGTGCCTGTGGCGACATGCATCACAGCGA
CGCAATGCTTGGGCCTACAC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTTRVLTGITTSGTPHLGNYVGAIRPAIQASAGADTESFYFLADLHSLIKAQDPARTQRSTLEIAATWLACGLDPDKVWF
YRQSDVPETTELMWLLTCVAGKGILNRAHAYKAAVDKNCADGEDEDAGVTAGLFMYPVLMAADILIFNAHKVPVGRDQIQ
HIEMARDFAQRFNHVYGREFFTLPEGVIDEQVSTLPGLDGRKMSKSYSNTIPLFAPREELRKLVFSILTDSRAPGEAKDT
QGSALFQLYQAFAAPQESAAFAQAFADGISWGDAKQQLFDRIDQDIAPLRARYEALMAEPAKIEAMLRAGGARLRARYAT
PLLAELRDAVGLRDLSRQAGAAVSAVGERIALPVFKQYRESDGQFYFKLNDGAGTLLLQSDGFASPRDAGQLIARLKQAA
QASDLQLPGVHAHMDADVILAAMHALREA

Sequences:

>Translated_429_residues
MTTRVLTGITTSGTPHLGNYVGAIRPAIQASAGADTESFYFLADLHSLIKAQDPARTQRSTLEIAATWLACGLDPDKVWF
YRQSDVPETTELMWLLTCVAGKGILNRAHAYKAAVDKNCADGEDEDAGVTAGLFMYPVLMAADILIFNAHKVPVGRDQIQ
HIEMARDFAQRFNHVYGREFFTLPEGVIDEQVSTLPGLDGRKMSKSYSNTIPLFAPREELRKLVFSILTDSRAPGEAKDT
QGSALFQLYQAFAAPQESAAFAQAFADGISWGDAKQQLFDRIDQDIAPLRARYEALMAEPAKIEAMLRAGGARLRARYAT
PLLAELRDAVGLRDLSRQAGAAVSAVGERIALPVFKQYRESDGQFYFKLNDGAGTLLLQSDGFASPRDAGQLIARLKQAA
QASDLQLPGVHAHMDADVILAAMHALREA
>Mature_428_residues
TTRVLTGITTSGTPHLGNYVGAIRPAIQASAGADTESFYFLADLHSLIKAQDPARTQRSTLEIAATWLACGLDPDKVWFY
RQSDVPETTELMWLLTCVAGKGILNRAHAYKAAVDKNCADGEDEDAGVTAGLFMYPVLMAADILIFNAHKVPVGRDQIQH
IEMARDFAQRFNHVYGREFFTLPEGVIDEQVSTLPGLDGRKMSKSYSNTIPLFAPREELRKLVFSILTDSRAPGEAKDTQ
GSALFQLYQAFAAPQESAAFAQAFADGISWGDAKQQLFDRIDQDIAPLRARYEALMAEPAKIEAMLRAGGARLRARYATP
LLAELRDAVGLRDLSRQAGAAVSAVGERIALPVFKQYRESDGQFYFKLNDGAGTLLLQSDGFASPRDAGQLIARLKQAAQ
ASDLQLPGVHAHMDADVILAAMHALREA

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=336, Percent_Identity=33.6309523809524, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI41352700, Length=185, Percent_Identity=43.7837837837838, Blast_Score=161, Evalue=1e-39,
Organism=Escherichia coli, GI1789786, Length=338, Percent_Identity=33.7278106508876, Blast_Score=164, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI71982800, Length=355, Percent_Identity=30.1408450704225, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71982793, Length=355, Percent_Identity=30.1408450704225, Blast_Score=142, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6320474, Length=344, Percent_Identity=29.9418604651163, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24666151, Length=342, Percent_Identity=29.5321637426901, Blast_Score=125, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR010879
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 46792; Mature: 46660

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRVLTGITTSGTPHLGNYVGAIRPAIQASAGADTESFYFLADLHSLIKAQDPARTQRS
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
TLEIAATWLACGLDPDKVWFYRQSDVPETTELMWLLTCVAGKGILNRAHAYKAAVDKNCA
HHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
DGEDEDAGVTAGLFMYPVLMAADILIFNAHKVPVGRDQIQHIEMARDFAQRFNHVYGREF
CCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
FTLPEGVIDEQVSTLPGLDGRKMSKSYSNTIPLFAPREELRKLVFSILTDSRAPGEAKDT
CCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
QGSALFQLYQAFAAPQESAAFAQAFADGISWGDAKQQLFDRIDQDIAPLRARYEALMAEP
CHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AKIEAMLRAGGARLRARYATPLLAELRDAVGLRDLSRQAGAAVSAVGERIALPVFKQYRE
HHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDGQFYFKLNDGAGTLLLQSDGFASPRDAGQLIARLKQAAQASDLQLPGVHAHMDADVIL
CCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
AAMHALREA
HHHHHHHCC
>Mature Secondary Structure 
TTRVLTGITTSGTPHLGNYVGAIRPAIQASAGADTESFYFLADLHSLIKAQDPARTQRS
CCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
TLEIAATWLACGLDPDKVWFYRQSDVPETTELMWLLTCVAGKGILNRAHAYKAAVDKNCA
HHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
DGEDEDAGVTAGLFMYPVLMAADILIFNAHKVPVGRDQIQHIEMARDFAQRFNHVYGREF
CCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
FTLPEGVIDEQVSTLPGLDGRKMSKSYSNTIPLFAPREELRKLVFSILTDSRAPGEAKDT
CCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
QGSALFQLYQAFAAPQESAAFAQAFADGISWGDAKQQLFDRIDQDIAPLRARYEALMAEP
CHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AKIEAMLRAGGARLRARYATPLLAELRDAVGLRDLSRQAGAAVSAVGERIALPVFKQYRE
HHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDGQFYFKLNDGAGTLLLQSDGFASPRDAGQLIARLKQAAQASDLQLPGVHAHMDADVIL
CCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
AAMHALREA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]