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The map label for this gene is cysJ [H]

Identifier: 84622027

GI number: 84622027

Start: 401015

End: 403681

Strand: Direct

Name: cysJ [H]

Synonym: XOO_0370

Alternate gene names: 84622027

Gene position: 401015-403681 (Clockwise)

Preceding gene: 84622025

Following gene: 84622029

Centisome position: 8.12

GC content: 66.14

Gene sequence:

>2667_bases
ATGAAACAAGGCTGGCCGTTTCCGAGGGAGCTGAACGACACGCTGCGGCAGGACGCCATCAGCCGGTGCCGAGTCGGATG
CCAGACTCATTGTCATCTACAATGGGCGAGCGTCCTGTTTCGTGTCCAGGTCTTGATCAAGTCGCTCCTGTTCCAGCTGC
ATTGGCTGCTCGGCATCACTGCCGGGCTGGTGCTATCGGTCATGGGGCTGACCGGCGCGTCGATGTCCTTCGAAAACGAG
ATCGTGCGCATGGCCAACCCGGCCAGCGCGCAGCTGGCGCAGCGGCATGCGGCGGGCGAGCGGCCCTTGCCGGTGGATGC
GCTGTTGCAACGGCTCGCTCTGGCGCCGACCGGTGCCGGACAAAAACACGCGGTCACGCGCCTGTTGATCGACCCCACCG
GTGCGCGTCCGTCCGCCGCCCGCCTATCCGGCAAGGGCGGTGGTCTGGTGTATTTCGATCCCTACACGGGAGAGCGGGTT
GCACCGCCACGGCTGAGCGCTGCGTTTGCCTTCATCGAAGACCTGCACCGCAATCTGACGGCCGGCAAGCGCGGGCAGGC
GGTCACCGGGGCGTGCGCACTGATCTTGCTGTTCTTCTGCGCATCGGGGCTGTATCTGCGCTGGCCGCGGCGGTGGTGGA
GCCCACGGACGTGGTGGGTGGTGGAATGGCGACGGCAGGGGCGCAGTTTTTTGTGGAGCCTGCACGCGGTGTTCGGTACC
TGGTGCTTGCTGGTGTATCTGCTGGTCGCCCTGACCGGGCTGACCTGGTCCTACACCTGGTATCGCGATGGCATGTTGGC
CTTGCTCGGCGCCGCGCCTGCGATACGCGGCGACAACGGCGATAACCGCCCGGCCACCATCGATGTCGCACGCGTGCAGC
GCACGCTCGATGGCATTCCCGCCACCCGCAGCGCCGCCTTGGATCTGCGTATTCCCACGCGCGCCGGGCAGCCGTTGAAT
GTGCGGTTCTTGCCTGACAATCCCGCGCACGATCGCGCCTACAACAGTCTTGATATTGCGCCGGACAGCGGAGCACTGCT
GCAGCGCCAGGACTACGCGCTGCTGCCGCGCGGGCAGCAATTGGCGGTGAGCATGTTTCCGCTGCATTCGGGCAGTTTCT
TCGGGTTGCCCGGGCGCATCGTGGTGATGCTGGCCAGCCTGGGCATGTCGGTGTTCTTCGTCACCGGCTGGATGCTGTAT
CTGGATCGGCGCCGAAAAAAACGCGAACTGCGCGCCGCGCGTGTGGTGTTGCAAGGCGCAGTACCAGCGTCGCAAGCCGC
ACCATGGGTGATTGCGTTCGCCAGTCAGAGCGGTTTTGCCGAACGCTTGGCCTGGCAGGCCGCCGCGCACCTGCAGGCGG
CCGGCTTGCCGGTGCAGGTGCGCCCGCTGGCGCAACTGGATGCGCAGGCGCTGCAACGCACGCGGCATGCGTTGTTTGTG
ATCAGCACGTTTGGCGATGGCGAGCCACCGGATGCGGCGCGCGGTTTCGAGCGTGGACTGCTGCGGCAACGCCTGGAATT
GCCGCACCTGACTTACGCGGTGCTGGCACTGGGCGACCGCCAATACGCACAGTTCTGCGGGTTCTCGCGGCGTGTCGAAC
AGTGGCTGGATGCGCAAGGGGCGCGCGCGCTGTTTCCTGCGGTGGAACTGGACAACGTCGATCCGCAGGCGCTGGCGCAA
TGGCATGCGCAGCTGGGCCAGATTGCCGGTGCACCGGTGAGCGCGGTGCCCCTGGCACGGCCCACCTTGACCGAATGGAC
GCTGTCCTCGCGCACGCATCTGAATCCGGGCAGCGACGGAGCGCCGATCTGGCGTATCGATCTGCAGCCACCGGCCGAAG
CACAGTGGCAGGCTGGCGACATTCTCGAAGTGCAACCCGCGCATGCCGAAGGGCAAGTGCAGGCTTGTCTGGCCGCATGG
GGTCTGTCGCCGGACGCGCTGGTGCATGTGGACGCGCAGCTACTGCCGCTGCAGCAGGCCGCCGCCGAGCGCGTGCTGCC
GGAGCCGCCTGCAACACCGCTTGACCATGCTGCAGATCCGCAAACCTGGCTGGATGCCTGCGCCTGGCTGCCCACGCGCG
ATTATTCGCTCGCCAGCGTGCCGGCTGATGGAAGCGCGATGGCCGTGGTGCGGTTGACCGCGCGTGCCGATGGCAGCCCC
GGTCTGGGTTCGGGTTGGCTGATCTGCCATGCGGGGATCGGCACGCCGGTGCGTGCACGGTTGCGCACCAATCCCGGCTT
TCATCGGGTCGAAACAATGCCGATGGTCTTGATCGGTAACGGCACTGGCATTGCCGGCCTGCGCGCGCTGCTGCGCGAAG
CCGAGGTGGCCGGCGTGCATGGGCACTGGTTGTTGTTCGGCGAACGACACGCGGCGCACGACCGCTTGTTTGCCGACGAG
CTGCAGACCTGGCAGGCCACTGGACATCTGCAGCAACTGGAGTGGGTGTTCTCGCGCGGTCAACCGCAAAAACGCTACGT
GCAACATCACCTGCGCGAGGCCGGCGACACGCTGCGACACTGGATCGACCGCGGCGCGGTCGTTTATGTCTGCGGCAGTC
TGGACAGCATGGCGCGCGAAGTCGATGTAACCTTGCGAGAACTGCTCGGCGACACGCGCTTGGAATCATTGACCGCGGCG
GGCCGTTATCGGCGCGATGTGTATTGA

Upstream 100 bases:

>100_bases
ACAGAGCTCGCTTGCCAAGAGGAGTGAGGAAGGTGGCAACGGGCGATGTCCAAACGATGACCGCGATATGTGCGGCAGAT
GAAGGCGTGCCGCTACGCGC

Downstream 100 bases:

>100_bases
GTGCGGTGATGGCTGCGGCATCACATCGGCCAGCAGAACGTGATGCCTGAACGTTAGGCAGCTGCAGGCGCAGAGCCTTA
GAGCGGCTGACAAAACGACT

Product: iron-uptake factor

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 888; Mature: 888

Protein sequence:

>888_residues
MKQGWPFPRELNDTLRQDAISRCRVGCQTHCHLQWASVLFRVQVLIKSLLFQLHWLLGITAGLVLSVMGLTGASMSFENE
IVRMANPASAQLAQRHAAGERPLPVDALLQRLALAPTGAGQKHAVTRLLIDPTGARPSAARLSGKGGGLVYFDPYTGERV
APPRLSAAFAFIEDLHRNLTAGKRGQAVTGACALILLFFCASGLYLRWPRRWWSPRTWWVVEWRRQGRSFLWSLHAVFGT
WCLLVYLLVALTGLTWSYTWYRDGMLALLGAAPAIRGDNGDNRPATIDVARVQRTLDGIPATRSAALDLRIPTRAGQPLN
VRFLPDNPAHDRAYNSLDIAPDSGALLQRQDYALLPRGQQLAVSMFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLY
LDRRRKKRELRAARVVLQGAVPASQAAPWVIAFASQSGFAERLAWQAAAHLQAAGLPVQVRPLAQLDAQALQRTRHALFV
ISTFGDGEPPDAARGFERGLLRQRLELPHLTYAVLALGDRQYAQFCGFSRRVEQWLDAQGARALFPAVELDNVDPQALAQ
WHAQLGQIAGAPVSAVPLARPTLTEWTLSSRTHLNPGSDGAPIWRIDLQPPAEAQWQAGDILEVQPAHAEGQVQACLAAW
GLSPDALVHVDAQLLPLQQAAAERVLPEPPATPLDHAADPQTWLDACAWLPTRDYSLASVPADGSAMAVVRLTARADGSP
GLGSGWLICHAGIGTPVRARLRTNPGFHRVETMPMVLIGNGTGIAGLRALLREAEVAGVHGHWLLFGERHAAHDRLFADE
LQTWQATGHLQQLEWVFSRGQPQKRYVQHHLREAGDTLRHWIDRGAVVYVCGSLDSMAREVDVTLRELLGDTRLESLTAA
GRYRRDVY

Sequences:

>Translated_888_residues
MKQGWPFPRELNDTLRQDAISRCRVGCQTHCHLQWASVLFRVQVLIKSLLFQLHWLLGITAGLVLSVMGLTGASMSFENE
IVRMANPASAQLAQRHAAGERPLPVDALLQRLALAPTGAGQKHAVTRLLIDPTGARPSAARLSGKGGGLVYFDPYTGERV
APPRLSAAFAFIEDLHRNLTAGKRGQAVTGACALILLFFCASGLYLRWPRRWWSPRTWWVVEWRRQGRSFLWSLHAVFGT
WCLLVYLLVALTGLTWSYTWYRDGMLALLGAAPAIRGDNGDNRPATIDVARVQRTLDGIPATRSAALDLRIPTRAGQPLN
VRFLPDNPAHDRAYNSLDIAPDSGALLQRQDYALLPRGQQLAVSMFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLY
LDRRRKKRELRAARVVLQGAVPASQAAPWVIAFASQSGFAERLAWQAAAHLQAAGLPVQVRPLAQLDAQALQRTRHALFV
ISTFGDGEPPDAARGFERGLLRQRLELPHLTYAVLALGDRQYAQFCGFSRRVEQWLDAQGARALFPAVELDNVDPQALAQ
WHAQLGQIAGAPVSAVPLARPTLTEWTLSSRTHLNPGSDGAPIWRIDLQPPAEAQWQAGDILEVQPAHAEGQVQACLAAW
GLSPDALVHVDAQLLPLQQAAAERVLPEPPATPLDHAADPQTWLDACAWLPTRDYSLASVPADGSAMAVVRLTARADGSP
GLGSGWLICHAGIGTPVRARLRTNPGFHRVETMPMVLIGNGTGIAGLRALLREAEVAGVHGHWLLFGERHAAHDRLFADE
LQTWQATGHLQQLEWVFSRGQPQKRYVQHHLREAGDTLRHWIDRGAVVYVCGSLDSMAREVDVTLRELLGDTRLESLTAA
GRYRRDVY
>Mature_888_residues
MKQGWPFPRELNDTLRQDAISRCRVGCQTHCHLQWASVLFRVQVLIKSLLFQLHWLLGITAGLVLSVMGLTGASMSFENE
IVRMANPASAQLAQRHAAGERPLPVDALLQRLALAPTGAGQKHAVTRLLIDPTGARPSAARLSGKGGGLVYFDPYTGERV
APPRLSAAFAFIEDLHRNLTAGKRGQAVTGACALILLFFCASGLYLRWPRRWWSPRTWWVVEWRRQGRSFLWSLHAVFGT
WCLLVYLLVALTGLTWSYTWYRDGMLALLGAAPAIRGDNGDNRPATIDVARVQRTLDGIPATRSAALDLRIPTRAGQPLN
VRFLPDNPAHDRAYNSLDIAPDSGALLQRQDYALLPRGQQLAVSMFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLY
LDRRRKKRELRAARVVLQGAVPASQAAPWVIAFASQSGFAERLAWQAAAHLQAAGLPVQVRPLAQLDAQALQRTRHALFV
ISTFGDGEPPDAARGFERGLLRQRLELPHLTYAVLALGDRQYAQFCGFSRRVEQWLDAQGARALFPAVELDNVDPQALAQ
WHAQLGQIAGAPVSAVPLARPTLTEWTLSSRTHLNPGSDGAPIWRIDLQPPAEAQWQAGDILEVQPAHAEGQVQACLAAW
GLSPDALVHVDAQLLPLQQAAAERVLPEPPATPLDHAADPQTWLDACAWLPTRDYSLASVPADGSAMAVVRLTARADGSP
GLGSGWLICHAGIGTPVRARLRTNPGFHRVETMPMVLIGNGTGIAGLRALLREAEVAGVHGHWLLFGERHAAHDRLFADE
LQTWQATGHLQQLEWVFSRGQPQKRYVQHHLREAGDTLRHWIDRGAVVYVCGSLDSMAREVDVTLRELLGDTRLESLTAA
GRYRRDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI221316709, Length=200, Percent_Identity=33.5, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI7657393, Length=205, Percent_Identity=32.6829268292683, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI127139033, Length=151, Percent_Identity=32.4503311258278, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI221316705, Length=214, Percent_Identity=31.7757009345794, Blast_Score=77, Evalue=9e-14,
Organism=Homo sapiens, GI221316707, Length=184, Percent_Identity=33.1521739130435, Blast_Score=74, Evalue=8e-13,
Organism=Escherichia coli, GI1789123, Length=540, Percent_Identity=27.7777777777778, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17554134, Length=212, Percent_Identity=34.4339622641509, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 97570; Mature: 97570

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQGWPFPRELNDTLRQDAISRCRVGCQTHCHLQWASVLFRVQVLIKSLLFQLHWLLGIT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLVLSVMGLTGASMSFENEIVRMANPASAQLAQRHAAGERPLPVDALLQRLALAPTGAG
HHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
QKHAVTRLLIDPTGARPSAARLSGKGGGLVYFDPYTGERVAPPRLSAAFAFIEDLHRNLT
CHHHEEEEEECCCCCCCCHHEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
AGKRGQAVTGACALILLFFCASGLYLRWPRRWWSPRTWWVVEWRRQGRSFLWSLHAVFGT
CCCCCCCHHHHHHHHHHHHHHCCCEEECCHHHCCCCEEEEEEHHHCCHHHHHHHHHHHHH
WCLLVYLLVALTGLTWSYTWYRDGMLALLGAAPAIRGDNGDNRPATIDVARVQRTLDGIP
HHHHHHHHHHHHCCCEEEEEHHCCHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCC
ATRSAALDLRIPTRAGQPLNVRFLPDNPAHDRAYNSLDIAPDSGALLQRQDYALLPRGQQ
CCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCEECCCCCE
LAVSMFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLYLDRRRKKRELRAARVVLQGA
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VPASQAAPWVIAFASQSGFAERLAWQAAAHLQAAGLPVQVRPLAQLDAQALQRTRHALFV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCEEEE
ISTFGDGEPPDAARGFERGLLRQRLELPHLTYAVLALGDRQYAQFCGFSRRVEQWLDAQG
EEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHCCCC
ARALFPAVELDNVDPQALAQWHAQLGQIAGAPVSAVPLARPTLTEWTLSSRTHLNPGSDG
CCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCC
APIWRIDLQPPAEAQWQAGDILEVQPAHAEGQVQACLAAWGLSPDALVHVDAQLLPLQQA
CCEEEEECCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHH
AAERVLPEPPATPLDHAADPQTWLDACAWLPTRDYSLASVPADGSAMAVVRLTARADGSP
HHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCEEEEEEEEECCCCCC
GLGSGWLICHAGIGTPVRARLRTNPGFHRVETMPMVLIGNGTGIAGLRALLREAEVAGVH
CCCCCEEEEECCCCCCEEEEECCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCC
GHWLLFGERHAAHDRLFADELQTWQATGHLQQLEWVFSRGQPQKRYVQHHLREAGDTLRH
CEEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
WIDRGAVVYVCGSLDSMAREVDVTLRELLGDTRLESLTAAGRYRRDVY
HHHCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKQGWPFPRELNDTLRQDAISRCRVGCQTHCHLQWASVLFRVQVLIKSLLFQLHWLLGIT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLVLSVMGLTGASMSFENEIVRMANPASAQLAQRHAAGERPLPVDALLQRLALAPTGAG
HHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
QKHAVTRLLIDPTGARPSAARLSGKGGGLVYFDPYTGERVAPPRLSAAFAFIEDLHRNLT
CHHHEEEEEECCCCCCCCHHEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
AGKRGQAVTGACALILLFFCASGLYLRWPRRWWSPRTWWVVEWRRQGRSFLWSLHAVFGT
CCCCCCCHHHHHHHHHHHHHHCCCEEECCHHHCCCCEEEEEEHHHCCHHHHHHHHHHHHH
WCLLVYLLVALTGLTWSYTWYRDGMLALLGAAPAIRGDNGDNRPATIDVARVQRTLDGIP
HHHHHHHHHHHHCCCEEEEEHHCCHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCC
ATRSAALDLRIPTRAGQPLNVRFLPDNPAHDRAYNSLDIAPDSGALLQRQDYALLPRGQQ
CCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCEECCCCCE
LAVSMFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLYLDRRRKKRELRAARVVLQGA
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VPASQAAPWVIAFASQSGFAERLAWQAAAHLQAAGLPVQVRPLAQLDAQALQRTRHALFV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCEEEE
ISTFGDGEPPDAARGFERGLLRQRLELPHLTYAVLALGDRQYAQFCGFSRRVEQWLDAQG
EEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHCCCC
ARALFPAVELDNVDPQALAQWHAQLGQIAGAPVSAVPLARPTLTEWTLSSRTHLNPGSDG
CCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCC
APIWRIDLQPPAEAQWQAGDILEVQPAHAEGQVQACLAAWGLSPDALVHVDAQLLPLQQA
CCEEEEECCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHH
AAERVLPEPPATPLDHAADPQTWLDACAWLPTRDYSLASVPADGSAMAVVRLTARADGSP
HHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCEEEEEEEEECCCCCC
GLGSGWLICHAGIGTPVRARLRTNPGFHRVETMPMVLIGNGTGIAGLRALLREAEVAGVH
CCCCCEEEEECCCCCCEEEEECCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCC
GHWLLFGERHAAHDRLFADELQTWQATGHLQQLEWVFSRGQPQKRYVQHHLREAGDTLRH
CEEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
WIDRGAVVYVCGSLDSMAREVDVTLRELLGDTRLESLTAAGRYRRDVY
HHHCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA