Click here to switch to the map view.

The map label for this gene is nadA

Identifier: 84489452

GI number: 84489452

Start: 751387

End: 752301

Strand: Direct

Name: nadA

Synonym: Msp_0643

Alternate gene names: 84489452

Gene position: 751387-752301 (Clockwise)

Preceding gene: 84489451

Following gene: 84489453

Centisome position: 42.51

GC content: 30.71

Gene sequence:

>915_bases
ATGACTAATGAGATTATAAGAGAAATTGAAGAATTAAAAAAAGAAAAAAATGCCATAATTCTTGCTCATAATTATCAACC
AAAAGAAATACAAGAAATAGCTGACTTTGTAGGGGATTCACTAGAATTATGTATAAAAGCAAATAATGTGGATGAAGCAG
ATATTATAGTATTTTGTGGTGTTAATTTCATGGCAGAAACTGCTTCTATTATTAGTCCAGATAAAAAGGTATTATTACCA
GATAATAGAGCTAATTGTCAAATGGCAGACATGGTTTCACTTGATGAATTGAAAAAAGCAAAAGCTGAACATCCAGATTG
TGAAGTAGTATTGTATGTAAATAGTAGAGCAGAAACTAAAAGTGAAGCTGACATAGTATGTACTTCTGCAAATGCTGGTA
AAATAGTTTCTAGTTTAAAATCTGATAATTTTATATTTGCACCAGACCATAATTTAGGTATCTACTCAGCAAAACAATCA
GGTAAAAATCCAATAATAGTTCCTGAAGATGGACATTGTTATGTACATACAATGTTTAAACCAGAAGATATTAAAAAAGC
ACGAGAAGATTATCCAAATGCTAAAATAGTGGTTCATCCAGAATGTAACGATGATGTAAGACAATTAGCAGATTATGTTG
AAAGTACTGGTGGAATGGTTAGACTTGCAAAAGATCCAGAAATTAAACAATTGGTTGTTGGAACTGAAATAGATCTTACT
ACACGACTTACAAGAGAAAATCCTGGAAAGGAATTTATTCCCCTCAGACGTGATGCTTTCTGTTTAACAATGAAGATTAT
TACTCTTGAAAAAGTACTTGAAGCACTTAAAGAAGAAAAATATGAAGTTGTTGTTGATAAAGAAATTGCTGCTAAGGCAC
GTGTTGGAATACAAAAAATGTTAGATTTATCATAA

Upstream 100 bases:

>100_bases
TGGATGTCAGCATATATTAGATGATGCAATTATTTAAATAATATTAAATATAACAAGAGTTATATTTTAAATAAAGAGTA
TAATAATAAGGGGTTTATAT

Downstream 100 bases:

>100_bases
ATAAATCTTTTTTAACTATTTTTTTATAATCCCCTATTATTTTGTAACATAACTTTTAAATATTTTCTAGTAATATAATT
TAAATATAAATTTCTAATGG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTNEIIREIEELKKEKNAIILAHNYQPKEIQEIADFVGDSLELCIKANNVDEADIIVFCGVNFMAETASIISPDKKVLLP
DNRANCQMADMVSLDELKKAKAEHPDCEVVLYVNSRAETKSEADIVCTSANAGKIVSSLKSDNFIFAPDHNLGIYSAKQS
GKNPIIVPEDGHCYVHTMFKPEDIKKAREDYPNAKIVVHPECNDDVRQLADYVESTGGMVRLAKDPEIKQLVVGTEIDLT
TRLTRENPGKEFIPLRRDAFCLTMKIITLEKVLEALKEEKYEVVVDKEIAAKARVGIQKMLDLS

Sequences:

>Translated_304_residues
MTNEIIREIEELKKEKNAIILAHNYQPKEIQEIADFVGDSLELCIKANNVDEADIIVFCGVNFMAETASIISPDKKVLLP
DNRANCQMADMVSLDELKKAKAEHPDCEVVLYVNSRAETKSEADIVCTSANAGKIVSSLKSDNFIFAPDHNLGIYSAKQS
GKNPIIVPEDGHCYVHTMFKPEDIKKAREDYPNAKIVVHPECNDDVRQLADYVESTGGMVRLAKDPEIKQLVVGTEIDLT
TRLTRENPGKEFIPLRRDAFCLTMKIITLEKVLEALKEEKYEVVVDKEIAAKARVGIQKMLDLS
>Mature_303_residues
TNEIIREIEELKKEKNAIILAHNYQPKEIQEIADFVGDSLELCIKANNVDEADIIVFCGVNFMAETASIISPDKKVLLPD
NRANCQMADMVSLDELKKAKAEHPDCEVVLYVNSRAETKSEADIVCTSANAGKIVSSLKSDNFIFAPDHNLGIYSAKQSG
KNPIIVPEDGHCYVHTMFKPEDIKKAREDYPNAKIVVHPECNDDVRQLADYVESTGGMVRLAKDPEIKQLVVGTEIDLTT
RLTRENPGKEFIPLRRDAFCLTMKIITLEKVLEALKEEKYEVVVDKEIAAKARVGIQKMLDLS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=314, Percent_Identity=34.7133757961783, Blast_Score=173, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34020; Mature: 33889

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNEIIREIEELKKEKNAIILAHNYQPKEIQEIADFVGDSLELCIKANNVDEADIIVFCG
CCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEC
VNFMAETASIISPDKKVLLPDNRANCQMADMVSLDELKKAKAEHPDCEVVLYVNSRAETK
CHHHHHHHHHCCCCCEEEECCCCCCCCHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCCC
SEADIVCTSANAGKIVSSLKSDNFIFAPDHNLGIYSAKQSGKNPIIVPEDGHCYVHTMFK
CCCCEEEECCCHHHHHHHHCCCCEEECCCCCCCEEECCCCCCCCEEEECCCCEEEEEECC
PEDIKKAREDYPNAKIVVHPECNDDVRQLADYVESTGGMVRLAKDPEIKQLVVGTEIDLT
CHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCEEEE
TRLTRENPGKEFIPLRRDAFCLTMKIITLEKVLEALKEEKYEVVVDKEIAAKARVGIQKM
EEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHH
LDLS
HCCC
>Mature Secondary Structure 
TNEIIREIEELKKEKNAIILAHNYQPKEIQEIADFVGDSLELCIKANNVDEADIIVFCG
CHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEC
VNFMAETASIISPDKKVLLPDNRANCQMADMVSLDELKKAKAEHPDCEVVLYVNSRAETK
CHHHHHHHHHCCCCCEEEECCCCCCCCHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCCC
SEADIVCTSANAGKIVSSLKSDNFIFAPDHNLGIYSAKQSGKNPIIVPEDGHCYVHTMFK
CCCCEEEECCCHHHHHHHHCCCCEEECCCCCCCEEECCCCCCCCEEEECCCCEEEEEECC
PEDIKKAREDYPNAKIVVHPECNDDVRQLADYVESTGGMVRLAKDPEIKQLVVGTEIDLT
CHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCEEEE
TRLTRENPGKEFIPLRRDAFCLTMKIITLEKVLEALKEEKYEVVVDKEIAAKARVGIQKM
EEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHH
LDLS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA