Click here to switch to the map view.

The map label for this gene is thrC

Identifier: 84489397

GI number: 84489397

Start: 679565

End: 680761

Strand: Direct

Name: thrC

Synonym: Msp_0588

Alternate gene names: 84489397

Gene position: 679565-680761 (Clockwise)

Preceding gene: 84489396

Following gene: 84489398

Centisome position: 38.45

GC content: 34.25

Gene sequence:

>1197_bases
ATGATACGATGTATTTCTTGTGGAAAAGAATACGATGATGATGAAATAATATATAACTGTACATGTGGTTCAATTCTTGA
AGTAGAAACTGAAGTTGAAGATATTCCACGTGAAACTTTTGAAAATAGACGAGATAATATCTGGAAATACAAAGAATTCT
TACCAGTAAATGCTGACAATAGAGTAAGTCTAGATGAAGGTGGAACACCATTTTGTAAATGTGAAAAAATAGGTAAAGAA
TTAGGTGTAGACCTTTATGTTAAAGTAGAAGGTTCAAATCCAACAGGTAGTTTTAAAGATAGGGGAATGAGTGTAGGTAC
AACAAAAGCAGTAGATCTTGGAGTAAATATGGTTGGTTGTGCTTCTACAGGAAACACTTCAGCTTCACTATCAGCATATG
CTGCACGTGCTGGACTTAAATGTGCAGTAGTATTACCATCAGGAAAAGTAGCTTTAGGAAAATTAGCTCAAGCAATGTTC
CATGGAGCAAAAGTATTTGCAATTGATGGAAACTTTGATGATGCATTAAAAACCATAACAGAATTAGCATTAGATGGTGA
ATTATATCTTCTAAATTCAATAAATCCATTCCGTTTAGAAGGACAAAAAACTATTGGATTTGAATTAGTACATGATCTTG
GATGGGAATCACCAGACAGAGTAATATTACCTGTAGGTAATGCAGGAAACATATCTGCAATATGGAAAGGTATAACTGAA
TTTAGAGATGCAGGATACATTAAAGATACTCCTATGATGACAGGTATTCAGGCAGTTAACAGTGCACCAATAGCAAATGC
AGTAAAAGCAGGAGAAGACACAGTAACTCCTGTAGAAAATCCAGATACTATTGCAACAGCTATAAGAATAGGAGCGCCTG
TAAGTTCAGTAAAAGCTATGAGAGCAATAAAAGAATCTAATGGTACTGCAGAAACAGTAACTGATGATGAAATATTAGAT
GCACAAAAATATCTTGCAAGAACAGAGGGTATTGGTGTAGAACCAGCATCTGCTGCAAGTATTGCAGGACTTAAAAAATT
AGTTGAAAATGGTGATGTTGATAAAGGTGAACGTGTTGTATGTATTGTAACAGGACATGTATTAAAAGATCCTAATGTAG
CAATAGATGCATGTGAAGATCCAACACCTGTATCATCAGATCCTAATGAAATAAGAAATGTTATAAGAACATTATAA

Upstream 100 bases:

>100_bases
ATAATTTATTATATTTAAAATAAATATATAATTAAATGAAATATTTTTTGAGTAATAATAAATATTACTAAATTAGATGA
ATTTAAAAAGGAGAATTTAG

Downstream 100 bases:

>100_bases
GTTCATATAACTTCCACTTTTTTTTATTAAAAAAAAAATCTTTTGATTATTATGATGATTATAATTACAGGTACTCCAGG
TACAGGTAAAACTACTGTAA

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MIRCISCGKEYDDDEIIYNCTCGSILEVETEVEDIPRETFENRRDNIWKYKEFLPVNADNRVSLDEGGTPFCKCEKIGKE
LGVDLYVKVEGSNPTGSFKDRGMSVGTTKAVDLGVNMVGCASTGNTSASLSAYAARAGLKCAVVLPSGKVALGKLAQAMF
HGAKVFAIDGNFDDALKTITELALDGELYLLNSINPFRLEGQKTIGFELVHDLGWESPDRVILPVGNAGNISAIWKGITE
FRDAGYIKDTPMMTGIQAVNSAPIANAVKAGEDTVTPVENPDTIATAIRIGAPVSSVKAMRAIKESNGTAETVTDDEILD
AQKYLARTEGIGVEPASAASIAGLKKLVENGDVDKGERVVCIVTGHVLKDPNVAIDACEDPTPVSSDPNEIRNVIRTL

Sequences:

>Translated_398_residues
MIRCISCGKEYDDDEIIYNCTCGSILEVETEVEDIPRETFENRRDNIWKYKEFLPVNADNRVSLDEGGTPFCKCEKIGKE
LGVDLYVKVEGSNPTGSFKDRGMSVGTTKAVDLGVNMVGCASTGNTSASLSAYAARAGLKCAVVLPSGKVALGKLAQAMF
HGAKVFAIDGNFDDALKTITELALDGELYLLNSINPFRLEGQKTIGFELVHDLGWESPDRVILPVGNAGNISAIWKGITE
FRDAGYIKDTPMMTGIQAVNSAPIANAVKAGEDTVTPVENPDTIATAIRIGAPVSSVKAMRAIKESNGTAETVTDDEILD
AQKYLARTEGIGVEPASAASIAGLKKLVENGDVDKGERVVCIVTGHVLKDPNVAIDACEDPTPVSSDPNEIRNVIRTL
>Mature_398_residues
MIRCISCGKEYDDDEIIYNCTCGSILEVETEVEDIPRETFENRRDNIWKYKEFLPVNADNRVSLDEGGTPFCKCEKIGKE
LGVDLYVKVEGSNPTGSFKDRGMSVGTTKAVDLGVNMVGCASTGNTSASLSAYAARAGLKCAVVLPSGKVALGKLAQAMF
HGAKVFAIDGNFDDALKTITELALDGELYLLNSINPFRLEGQKTIGFELVHDLGWESPDRVILPVGNAGNISAIWKGITE
FRDAGYIKDTPMMTGIQAVNSAPIANAVKAGEDTVTPVENPDTIATAIRIGAPVSSVKAMRAIKESNGTAETVTDDEILD
AQKYLARTEGIGVEPASAASIAGLKKLVENGDVDKGERVVCIVTGHVLKDPNVAIDACEDPTPVSSDPNEIRNVIRTL

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790207, Length=301, Percent_Identity=28.9036544850498, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 42506; Mature: 42506

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRCISCGKEYDDDEIIYNCTCGSILEVETEVEDIPRETFENRRDNIWKYKEFLPVNADN
CEEEEECCCCCCCCCEEEEECCCCEEEEEHHHHHCCHHHHHHHHCCCHHHHHEECCCCCC
RVSLDEGGTPFCKCEKIGKELGVDLYVKVEGSNPTGSFKDRGMSVGTTKAVDLGVNMVGC
EEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHCCCCCCCCEEEECCCEEEEE
ASTGNTSASLSAYAARAGLKCAVVLPSGKVALGKLAQAMFHGAKVFAIDGNFDDALKTIT
CCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
ELALDGELYLLNSINPFRLEGQKTIGFELVHDLGWESPDRVILPVGNAGNISAIWKGITE
HHHCCCCEEEEECCCCEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
FRDAGYIKDTPMMTGIQAVNSAPIANAVKAGEDTVTPVENPDTIATAIRIGAPVSSVKAM
HHHCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHHHEECCCCHHHHHHH
RAIKESNGTAETVTDDEILDAQKYLARTEGIGVEPASAASIAGLKKLVENGDVDKGERVV
HHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
CIVTGHVLKDPNVAIDACEDPTPVSSDPNEIRNVIRTL
EEEECCEECCCCCEEECCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MIRCISCGKEYDDDEIIYNCTCGSILEVETEVEDIPRETFENRRDNIWKYKEFLPVNADN
CEEEEECCCCCCCCCEEEEECCCCEEEEEHHHHHCCHHHHHHHHCCCHHHHHEECCCCCC
RVSLDEGGTPFCKCEKIGKELGVDLYVKVEGSNPTGSFKDRGMSVGTTKAVDLGVNMVGC
EEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHCCCCCCCCEEEECCCEEEEE
ASTGNTSASLSAYAARAGLKCAVVLPSGKVALGKLAQAMFHGAKVFAIDGNFDDALKTIT
CCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
ELALDGELYLLNSINPFRLEGQKTIGFELVHDLGWESPDRVILPVGNAGNISAIWKGITE
HHHCCCCEEEEECCCCEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
FRDAGYIKDTPMMTGIQAVNSAPIANAVKAGEDTVTPVENPDTIATAIRIGAPVSSVKAM
HHHCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHHHEECCCCHHHHHHH
RAIKESNGTAETVTDDEILDAQKYLARTEGIGVEPASAASIAGLKKLVENGDVDKGERVV
HHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
CIVTGHVLKDPNVAIDACEDPTPVSSDPNEIRNVIRTL
EEEECCEECCCCCEEECCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]