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The map label for this gene is coaD [H]

Identifier: 84489324

GI number: 84489324

Start: 608523

End: 608981

Strand: Direct

Name: coaD [H]

Synonym: Msp_0514

Alternate gene names: 84489324

Gene position: 608523-608981 (Clockwise)

Preceding gene: 84489319

Following gene: 84489325

Centisome position: 34.43

GC content: 29.85

Gene sequence:

>459_bases
ATGAAGGCGAAATATAGAAAAATAGCTGTGGGAGGAACGTTCGATAAACTACATAAGGGACATGAAGCCCTACTAGATGC
AGCTTTTACAATGGCAGATGAAGTTTTAATTGGTATAACTTCAGATGATTTTGCATCAATGAAAAATCACGTAATTGAAC
CATGTGAAGTCAGAATAACTAAATTAAAATCAATAATAAAACCATACAACAAAAAATATATAATTAAAAAAATCATGGAT
TCAAATGGAACTGCAGATACTGATAAAAATCTTGATGCAATAGTAGTAAGTAAGGAAACAGAAAAATCAGCCATTGAAAT
AAACAAGATACGATGTGAAAATGGTTTAAATCCATTGGATATTATAATAATTGAATGGATATTAGCTGATGATGGTGTTC
CAATTTCTTCAACCCGTATAAGAAAAGGGGAAATAGATCAAAAAGGAACTTTATTATAA

Upstream 100 bases:

>100_bases
AGTATTTCTATAAATTCCTTTAAATAATATTATTTAGAAATATAAAACTAGTGAATATTTTTAAACTTATTTTAAAGATA
AAATAGTAAAGGAATTTTAT

Downstream 100 bases:

>100_bases
CTTCTTTTTAGATATTAGATAGTATGGAATTTCTACTGGTGTTTAAGATTATCTGTGTGTGATTGTTTATTTCATTTAGA
TAATTAATTGTAAAATGGGC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKAKYRKIAVGGTFDKLHKGHEALLDAAFTMADEVLIGITSDDFASMKNHVIEPCEVRITKLKSIIKPYNKKYIIKKIMD
SNGTADTDKNLDAIVVSKETEKSAIEINKIRCENGLNPLDIIIIEWILADDGVPISSTRIRKGEIDQKGTLL

Sequences:

>Translated_152_residues
MKAKYRKIAVGGTFDKLHKGHEALLDAAFTMADEVLIGITSDDFASMKNHVIEPCEVRITKLKSIIKPYNKKYIIKKIMD
SNGTADTDKNLDAIVVSKETEKSAIEINKIRCENGLNPLDIIIIEWILADDGVPISSTRIRKGEIDQKGTLL
>Mature_152_residues
MKAKYRKIAVGGTFDKLHKGHEALLDAAFTMADEVLIGITSDDFASMKNHVIEPCEVRITKLKSIIKPYNKKYIIKKIMD
SNGTADTDKNLDAIVVSKETEKSAIEINKIRCENGLNPLDIIIIEWILADDGVPISSTRIRKGEIDQKGTLL

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG1019

COG function: function code R; Predicted nucleotidyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic CoaD family [H]

Homologues:

Organism=Homo sapiens, GI110227605, Length=151, Percent_Identity=34.4370860927152, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI110227603, Length=151, Percent_Identity=34.4370860927152, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI110227601, Length=151, Percent_Identity=34.4370860927152, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI205277394, Length=151, Percent_Identity=34.4370860927152, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25143409, Length=147, Percent_Identity=37.4149659863946, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321716, Length=148, Percent_Identity=31.0810810810811, Blast_Score=69, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24658602, Length=153, Percent_Identity=30.0653594771242, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 16927; Mature: 16927

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKYRKIAVGGTFDKLHKGHEALLDAAFTMADEVLIGITSDDFASMKNHVIEPCEVRIT
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCHHHHHH
KLKSIIKPYNKKYIIKKIMDSNGTADTDKNLDAIVVSKETEKSAIEINKIRCENGLNPLD
HHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCHHH
IIIIEWILADDGVPISSTRIRKGEIDQKGTLL
HHEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKAKYRKIAVGGTFDKLHKGHEALLDAAFTMADEVLIGITSDDFASMKNHVIEPCEVRIT
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCHHHHHH
KLKSIIKPYNKKYIIKKIMDSNGTADTDKNLDAIVVSKETEKSAIEINKIRCENGLNPLD
HHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCHHH
IIIIEWILADDGVPISSTRIRKGEIDQKGTLL
HHEEEEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]