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The map label for this gene is mtrA

Identifier: 84489125

GI number: 84489125

Start: 363786

End: 364535

Strand: Direct

Name: mtrA

Synonym: Msp_0304

Alternate gene names: 84489125

Gene position: 363786-364535 (Clockwise)

Preceding gene: 84489124

Following gene: 84489126

Centisome position: 20.58

GC content: 31.33

Gene sequence:

>750_bases
ATGGCAGATAAAAAAGAAGTTATTCAAAATTGGCCCTTAGAAACTGGAGATTATGCAGTGGGAAATGTTGAAAGTCCAGT
AGCAGTAGTCTCTCTAGGTTCTAATATGAATGATGAATTGGTAGCTGCAGGGGCTGCAATTTCAGGACCATTACACACAG
AAAACTTGGGAATAGAAAAGGTTGTTGCAAATATAATATCAAATTCAAACATACGTTATGTTCTTATATGTGGATCTGAG
GTTCAAGGACATATTACTGGTAAAACAGTTGAAGCTTTATATGAAAATGGTATTGATGAAGAGAAAAAATCAATTATTGG
TTCTCCTGGAGCTATTCCATTCGTTGAAAACTTACCAGTAGAAGCTGTTGAAAGATTCCAAAAACAAGTTTCTATTGTTA
GTATGATAAATAATGAGGATGTTAGTGAAATATCATCTAAAATAGATGAATGTATTAGTAATGATCCTGGAGCATATGAT
GAAGATGCAATGATTGTTGAATTTAATGAAACACCTGAAGAGGAGTTTGAAGTTGATGAAGTCACATTTTCTGATGATTC
AGCAGTTGATTTAGCATCAATAGTTCTACTTGAGGTTGAAAATCGTATAAGTATGATGAATAATGAAATAAAACAAATTG
CTTCTTTAGAAAAAATATCTTCAGGATATTATGCTGGAAAAATAGAAGGTATAGTTATTGGATTTATTTTAACATTGGTT
TTTCTTATAATTATTATTCAAGGTTTGTGA

Upstream 100 bases:

>100_bases
GGAATATATGAAAAAGCAGGATTAATTACAAACATTGTAATTGGTGTGATTATAGCATTAGTTTTCATACTTTTATTAGT
ATAAAATAAGGGGAGATTAT

Downstream 100 bases:

>100_bases
GTAAATGATATTAGATAATATAGGTAAGTTAGTTGAATCTATAGAATATAAATCTCAGCTAATTGGAAGAAAAGAAAGAT
TAGTTTGTGGTGTTGAAAAA

Product: tetrahydromethanopterin S-methyltransferase subunit A

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MADKKEVIQNWPLETGDYAVGNVESPVAVVSLGSNMNDELVAAGAAISGPLHTENLGIEKVVANIISNSNIRYVLICGSE
VQGHITGKTVEALYENGIDEEKKSIIGSPGAIPFVENLPVEAVERFQKQVSIVSMINNEDVSEISSKIDECISNDPGAYD
EDAMIVEFNETPEEEFEVDEVTFSDDSAVDLASIVLLEVENRISMMNNEIKQIASLEKISSGYYAGKIEGIVIGFILTLV
FLIIIIQGL

Sequences:

>Translated_249_residues
MADKKEVIQNWPLETGDYAVGNVESPVAVVSLGSNMNDELVAAGAAISGPLHTENLGIEKVVANIISNSNIRYVLICGSE
VQGHITGKTVEALYENGIDEEKKSIIGSPGAIPFVENLPVEAVERFQKQVSIVSMINNEDVSEISSKIDECISNDPGAYD
EDAMIVEFNETPEEEFEVDEVTFSDDSAVDLASIVLLEVENRISMMNNEIKQIASLEKISSGYYAGKIEGIVIGFILTLV
FLIIIIQGL
>Mature_248_residues
ADKKEVIQNWPLETGDYAVGNVESPVAVVSLGSNMNDELVAAGAAISGPLHTENLGIEKVVANIISNSNIRYVLICGSEV
QGHITGKTVEALYENGIDEEKKSIIGSPGAIPFVENLPVEAVERFQKQVSIVSMINNEDVSEISSKIDECISNDPGAYDE
DAMIVEFNETPEEEFEVDEVTFSDDSAVDLASIVLLEVENRISMMNNEIKQIASLEKISSGYYAGKIEGIVIGFILTLVF
LIIIIQGL

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step

COG id: COG4063

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit A

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MtrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRA_METST (Q2NI29)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447357.1
- STRING:   Q2NI29
- GeneID:   3854951
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0304
- NMPDR:   fig|339860.6.peg.295
- eggNOG:   arNOG07825
- HOGENOM:   HBG542039
- OMA:   AEPDIES
- ProtClustDB:   PRK00964
- BioCyc:   MSTA339860:MSP_0304-MONOMER
- GO:   GO:0005737
- GO:   GO:0015948
- HAMAP:   MF_01093
- InterPro:   IPR005778
- InterPro:   IPR013340
- TIGRFAMs:   TIGR01111

Pfam domain/function: PF04208 MtrA

EC number: =2.1.1.86

Molecular weight: Translated: 26970; Mature: 26839

Theoretical pI: Translated: 3.83; Mature: 3.83

Prosite motif: NA

Important sites: BINDING 84-84

Signals:

None

Transmembrane regions:

HASH(0x14df0760)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKEVIQNWPLETGDYAVGNVESPVAVVSLGSNMNDELVAAGAAISGPLHTENLGIEK
CCCHHHHHHHCCCCCCCEECCCCCCCEEEEEECCCCCHHHEECCCCCCCCCCCCCCCHHH
VVANIISNSNIRYVLICGSEVQGHITGKTVEALYENGIDEEKKSIIGSPGAIPFVENLPV
HHHHHHCCCCEEEEEEECCCCCCEECHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHCCCH
EAVERFQKQVSIVSMINNEDVSEISSKIDECISNDPGAYDEDAMIVEFNETPEEEFEVDE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCE
VTFSDDSAVDLASIVLLEVENRISMMNNEIKQIASLEKISSGYYAGKIEGIVIGFILTLV
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
FLIIIIQGL
HHHHHHCCH
>Mature Secondary Structure 
ADKKEVIQNWPLETGDYAVGNVESPVAVVSLGSNMNDELVAAGAAISGPLHTENLGIEK
CCHHHHHHHCCCCCCCEECCCCCCCEEEEEECCCCCHHHEECCCCCCCCCCCCCCCHHH
VVANIISNSNIRYVLICGSEVQGHITGKTVEALYENGIDEEKKSIIGSPGAIPFVENLPV
HHHHHHCCCCEEEEEEECCCCCCEECHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHCCCH
EAVERFQKQVSIVSMINNEDVSEISSKIDECISNDPGAYDEDAMIVEFNETPEEEFEVDE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCE
VTFSDDSAVDLASIVLLEVENRISMMNNEIKQIASLEKISSGYYAGKIEGIVIGFILTLV
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
FLIIIIQGL
HHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA