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The map label for this gene is udg [H]

Identifier: 84489038

GI number: 84489038

Start: 258231

End: 259550

Strand: Direct

Name: udg [H]

Synonym: Msp_0210

Alternate gene names: 84489038

Gene position: 258231-259550 (Clockwise)

Preceding gene: 84489037

Following gene: 84489041

Centisome position: 14.61

GC content: 30.08

Gene sequence:

>1320_bases
ATGAATATTACAATAATTGGGACAGGATATGTGGGATTAGTAACAGGTACTTGTTTTTCAGAGATGGGAAATGAAGTATA
CTGTGTGGATGTTATTGAAGAAAAAATAGAATCCCTAAAACAAGGAATAATACCAATATATGAACCAGGACTTGAAGAAT
TAATAAAACATAACTACAACAATGGAAACCTACATTTTACAACAGATCTATTTGAAGGTCTATCCGATTCACAACTCTGT
TTTATAGCAGTAGGAACACCTATGGGTGAAGATGGAAGTGCAGATTTAAGATATGTAAGACAGGTTGCAAAACAAATAGG
ACAAACAATAACTCAGGACATAATTGTAGTTGATAAATCAACAGTTCCAGTGGGAACAGCAGATGAAGTTGAAACAATAA
TAAATAAAGAACTTGATAAAAGAAATAAAAACTACAAGGTAACAGTTGTTTCAAATCCAGAATTTCTAAAGGAAGGAACA
GCAGTAAATGATTTTATGCACCCCGAAAGGGTTATTGTTGGAACAGATGATGATTCTGCAGCAGAAATTATGAAAGAATT
ATATGATCCATTTACTAAAAATCATGAAAGAATGATAATAATGGATGTACGTAGTGCAGAAATGACAAAATATGCATCAA
ATTCAATGCTTGCAAATAGAATATCCTTTATGAATGAAATGGCAAATATATGTGATAAAATCGGTGCAAATATTGATAAT
GTACGTAGAGGTATGGGTAGTGATTCAAGAATAGGTCATAGTTTCCTATATCCTGGATGTGGATATGGTGGAAGTTGTTT
TCCTAAGGATGTTACAGCTCTAATAAAAACAGCACAAGACAATGGATTAAATCCTGTACTACTAAAAAGTGTAGAAGAAG
TAAATCATAATCAGAAATATTATTTAATAAATAAGATAATTAACATATTTGGAGAAGATTTATCAGGATTAACATTTGCA
CTATGGGGATTGGCATTTAAGCCTGAAACAGATGATATGAGAGAAGCATCATCAATTATAATAGTAGAAAATCTTCTAAA
AATGGGAGCAAAAGTTAATGTCTATGATCCAAAGGCAATGGATGTTGCTAAAGAATTTTACTTTAAAGATTTGGATGTAA
ATTATTTTAGTGACAAGTATTCAGTTTTAGAAGATGCTGATGCTTTGATTTTAGTTACTGAGTGGAAAGAATTTAGAAAT
CCTAATTTTAATAAAATAAAATCTCTACTTAAAAATAACATAATATTTGATGGCAGAAATCAGTATAAAAATAGTTATAT
GAAAAAATTAGACTTTGAATATCATGCTGTAGGAAAATAA

Upstream 100 bases:

>100_bases
CTTCGATCAAATAAAACTAACGAACACTGAGAAGGTATTTGAAAATAACAGATTCATAATATGTAAGATAAAGTCTTAAA
TTCAAATGGAGGGAAATTAC

Downstream 100 bases:

>100_bases
AATTATTCTCCTACAAACATTACTTTTTTTTATATTACATTGACATATAAATGACGTTTAATATATGGTTGTCCACGTTG
TGTGTATAAAACATACTGTA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MNITIIGTGYVGLVTGTCFSEMGNEVYCVDVIEEKIESLKQGIIPIYEPGLEELIKHNYNNGNLHFTTDLFEGLSDSQLC
FIAVGTPMGEDGSADLRYVRQVAKQIGQTITQDIIVVDKSTVPVGTADEVETIINKELDKRNKNYKVTVVSNPEFLKEGT
AVNDFMHPERVIVGTDDDSAAEIMKELYDPFTKNHERMIIMDVRSAEMTKYASNSMLANRISFMNEMANICDKIGANIDN
VRRGMGSDSRIGHSFLYPGCGYGGSCFPKDVTALIKTAQDNGLNPVLLKSVEEVNHNQKYYLINKIINIFGEDLSGLTFA
LWGLAFKPETDDMREASSIIIVENLLKMGAKVNVYDPKAMDVAKEFYFKDLDVNYFSDKYSVLEDADALILVTEWKEFRN
PNFNKIKSLLKNNIIFDGRNQYKNSYMKKLDFEYHAVGK

Sequences:

>Translated_439_residues
MNITIIGTGYVGLVTGTCFSEMGNEVYCVDVIEEKIESLKQGIIPIYEPGLEELIKHNYNNGNLHFTTDLFEGLSDSQLC
FIAVGTPMGEDGSADLRYVRQVAKQIGQTITQDIIVVDKSTVPVGTADEVETIINKELDKRNKNYKVTVVSNPEFLKEGT
AVNDFMHPERVIVGTDDDSAAEIMKELYDPFTKNHERMIIMDVRSAEMTKYASNSMLANRISFMNEMANICDKIGANIDN
VRRGMGSDSRIGHSFLYPGCGYGGSCFPKDVTALIKTAQDNGLNPVLLKSVEEVNHNQKYYLINKIINIFGEDLSGLTFA
LWGLAFKPETDDMREASSIIIVENLLKMGAKVNVYDPKAMDVAKEFYFKDLDVNYFSDKYSVLEDADALILVTEWKEFRN
PNFNKIKSLLKNNIIFDGRNQYKNSYMKKLDFEYHAVGK
>Mature_439_residues
MNITIIGTGYVGLVTGTCFSEMGNEVYCVDVIEEKIESLKQGIIPIYEPGLEELIKHNYNNGNLHFTTDLFEGLSDSQLC
FIAVGTPMGEDGSADLRYVRQVAKQIGQTITQDIIVVDKSTVPVGTADEVETIINKELDKRNKNYKVTVVSNPEFLKEGT
AVNDFMHPERVIVGTDDDSAAEIMKELYDPFTKNHERMIIMDVRSAEMTKYASNSMLANRISFMNEMANICDKIGANIDN
VRRGMGSDSRIGHSFLYPGCGYGGSCFPKDVTALIKTAQDNGLNPVLLKSVEEVNHNQKYYLINKIINIFGEDLSGLTFA
LWGLAFKPETDDMREASSIIIVENLLKMGAKVNVYDPKAMDVAKEFYFKDLDVNYFSDKYSVLEDADALILVTEWKEFRN
PNFNKIKSLLKNNIIFDGRNQYKNSYMKKLDFEYHAVGK

Specific function: Catalyzes The Oxidation Of Udp-Mannac To Udp-N- Acetylmannosaminuronic Acid (Udp-Mannaca). [C]

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=466, Percent_Identity=33.9055793991416, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI296040438, Length=374, Percent_Identity=33.1550802139037, Blast_Score=202, Evalue=7e-52,
Organism=Homo sapiens, GI296040443, Length=315, Percent_Identity=33.015873015873, Blast_Score=175, Evalue=7e-44,
Organism=Escherichia coli, GI48994968, Length=412, Percent_Identity=26.9417475728155, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1788340, Length=361, Percent_Identity=27.1468144044321, Blast_Score=141, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17560350, Length=459, Percent_Identity=33.9869281045752, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI17136908, Length=467, Percent_Identity=34.6895074946467, Blast_Score=261, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49408; Mature: 49408

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITIIGTGYVGLVTGTCFSEMGNEVYCVDVIEEKIESLKQGIIPIYEPGLEELIKHNYN
CEEEEEECCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
NGNLHFTTDLFEGLSDSQLCFIAVGTPMGEDGSADLRYVRQVAKQIGQTITQDIIVVDKS
CCCEEEEHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECC
TVPVGTADEVETIINKELDKRNKNYKVTVVSNPEFLKEGTAVNDFMHPERVIVGTDDDSA
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCHHHCCCCCEEEEECCCCHH
AEIMKELYDPFTKNHERMIIMDVRSAEMTKYASNSMLANRISFMNEMANICDKIGANIDN
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRRGMGSDSRIGHSFLYPGCGYGGSCFPKDVTALIKTAQDNGLNPVLLKSVEEVNHNQKY
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCE
YLINKIINIFGEDLSGLTFALWGLAFKPETDDMREASSIIIVENLLKMGAKVNVYDPKAM
EHHHHHHHHHCCCCCHHHHHHHHCEECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHH
DVAKEFYFKDLDVNYFSDKYSVLEDADALILVTEWKEFRNPNFNKIKSLLKNNIIFDGRN
HHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEEEEHHHHCCCCHHHHHHHHHCCCEECCCH
QYKNSYMKKLDFEYHAVGK
HHHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MNITIIGTGYVGLVTGTCFSEMGNEVYCVDVIEEKIESLKQGIIPIYEPGLEELIKHNYN
CEEEEEECCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
NGNLHFTTDLFEGLSDSQLCFIAVGTPMGEDGSADLRYVRQVAKQIGQTITQDIIVVDKS
CCCEEEEHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECC
TVPVGTADEVETIINKELDKRNKNYKVTVVSNPEFLKEGTAVNDFMHPERVIVGTDDDSA
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCHHHCCCCCEEEEECCCCHH
AEIMKELYDPFTKNHERMIIMDVRSAEMTKYASNSMLANRISFMNEMANICDKIGANIDN
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRRGMGSDSRIGHSFLYPGCGYGGSCFPKDVTALIKTAQDNGLNPVLLKSVEEVNHNQKY
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCE
YLINKIINIFGEDLSGLTFALWGLAFKPETDDMREASSIIIVENLLKMGAKVNVYDPKAM
EHHHHHHHHHCCCCCHHHHHHHHCEECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHH
DVAKEFYFKDLDVNYFSDKYSVLEDADALILVTEWKEFRNPNFNKIKSLLKNNIIFDGRN
HHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEEEEHHHHCCCCHHHHHHHHHCCCEECCCH
QYKNSYMKKLDFEYHAVGK
HHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]