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The map label for this gene is serB [H]

Identifier: 83721426

GI number: 83721426

Start: 2547819

End: 2548664

Strand: Reverse

Name: serB [H]

Synonym: BTH_I2264

Alternate gene names: 83721426

Gene position: 2548664-2547819 (Counterclockwise)

Preceding gene: 83719317

Following gene: 83719596

Centisome position: 66.91

GC content: 67.73

Gene sequence:

>846_bases
ATGACCACGAATCTCGTCATTCAAAGCACTGCACCGATCTCCGACGCGCATCACAAGCCGCTCGCCGCGCTCGCGCGCGG
CGAGCGCGTCGTTGCGCTCGACGCGCAATCGATCCGCATCGAGGGCGCCGACCCCGCGCAGCGCCCCGACATCGACGCAT
ACTGCGGCGCGCACGCGCTCGACTACGCGTTCGTCGACGCGGCCCGCAAGCTTGCCGACTTCGGCCTCGTCGCGATGGAC
ATGGATTCGACGCTGATCACGATCGAGTGCATCGACGAGATCGCGGACTTCTGCGGCCTGAAGGCCGAGGTTTCGGCGAT
CACCGAGGCGGCGATGCGCGGCGAGATCAAGGACTTCAACGAGAGCCTGACACGTCGTGTCGCGCTGCTCGCGGGCCTCG
ACGCGAGCGCGCTCGAGCGCGTCTACGAAGAACGGCTGCGGCTGTCGCCGGGCGCCGAATCGATGCTGGCCGGCGTGAAG
GCCGCGGGCCTGAAGACCTTGCTCGTATCGGGCGGCTTCACGTTCTTCACCGAGCGCCTGAAGGCACGGCTCGGCCTCGA
CTTCGCCTACTCGAACACGCTCGAGATCGTCGACGGCAAGCTGACGGGCAAGGTCGTCGGCGAAATCGTCAATGCGGACG
TGAAGGCGCGCGCGGTGCGCGACACGTGCACGGCGCTCGGCATCGAGCCCGCGCGGGCGATCGTCCTCGGCGACGGGTCG
AACGACCTGAAGATGATGGCTGCCGGCGGCTTCTCGATCGCGTTTCGCGCAAAACCGGTCGTGCGCCGCGCGGCGAGCGC
CGCGTTCGACCATGTCGGCCTCGACGGATTGCTGCGGCTGTTCTGA

Upstream 100 bases:

>100_bases
CTACCGCCCGTCCGCCGGCTCTGCGCCGCGACCGGCTACAATAGCGGGTTCGCCGCGTCGCCGTTGCCGGCGCCGCCATC
CGCTCCACCGTGACAATTCC

Downstream 100 bases:

>100_bases
GGCCGCTCCGGCTCGCTCGGGAGCGCGGCGCACGCGCGATCGCACCGCCACCGTCTCCCCCCGTCCAACGAAAAACGGCG
CTGCGGGCCTGCCGCCCCAG

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTTNLVIQSTAPISDAHHKPLAALARGERVVALDAQSIRIEGADPAQRPDIDAYCGAHALDYAFVDAARKLADFGLVAMD
MDSTLITIECIDEIADFCGLKAEVSAITEAAMRGEIKDFNESLTRRVALLAGLDASALERVYEERLRLSPGAESMLAGVK
AAGLKTLLVSGGFTFFTERLKARLGLDFAYSNTLEIVDGKLTGKVVGEIVNADVKARAVRDTCTALGIEPARAIVLGDGS
NDLKMMAAGGFSIAFRAKPVVRRAASAAFDHVGLDGLLRLF

Sequences:

>Translated_281_residues
MTTNLVIQSTAPISDAHHKPLAALARGERVVALDAQSIRIEGADPAQRPDIDAYCGAHALDYAFVDAARKLADFGLVAMD
MDSTLITIECIDEIADFCGLKAEVSAITEAAMRGEIKDFNESLTRRVALLAGLDASALERVYEERLRLSPGAESMLAGVK
AAGLKTLLVSGGFTFFTERLKARLGLDFAYSNTLEIVDGKLTGKVVGEIVNADVKARAVRDTCTALGIEPARAIVLGDGS
NDLKMMAAGGFSIAFRAKPVVRRAASAAFDHVGLDGLLRLF
>Mature_280_residues
TTNLVIQSTAPISDAHHKPLAALARGERVVALDAQSIRIEGADPAQRPDIDAYCGAHALDYAFVDAARKLADFGLVAMDM
DSTLITIECIDEIADFCGLKAEVSAITEAAMRGEIKDFNESLTRRVALLAGLDASALERVYEERLRLSPGAESMLAGVKA
AGLKTLLVSGGFTFFTERLKARLGLDFAYSNTLEIVDGKLTGKVVGEIVNADVKARAVRDTCTALGIEPARAIVLGDGSN
DLKMMAAGGFSIAFRAKPVVRRAASAAFDHVGLDGLLRLF

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=110, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1790849, Length=247, Percent_Identity=42.914979757085, Blast_Score=171, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6321647, Length=207, Percent_Identity=38.6473429951691, Blast_Score=141, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24661601, Length=224, Percent_Identity=27.6785714285714, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 29842; Mature: 29710

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNLVIQSTAPISDAHHKPLAALARGERVVALDAQSIRIEGADPAQRPDIDAYCGAHAL
CCCCEEEECCCCCCCCCCCHHHHHHCCCEEEEEECCEEEEECCCCCCCCCCHHHHCHHHH
DYAFVDAARKLADFGLVAMDMDSTLITIECIDEIADFCGLKAEVSAITEAAMRGEIKDFN
HHHHHHHHHHHHHCCEEEEECCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
ESLTRRVALLAGLDASALERVYEERLRLSPGAESMLAGVKAAGLKTLLVSGGFTFFTERL
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHCCCHHHHHHHH
KARLGLDFAYSNTLEIVDGKLTGKVVGEIVNADVKARAVRDTCTALGIEPARAIVLGDGS
HHHHCCEEEECCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCC
NDLKMMAAGGFSIAFRAKPVVRRAASAAFDHVGLDGLLRLF
CCEEEEEECCEEEEEECCHHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
TTNLVIQSTAPISDAHHKPLAALARGERVVALDAQSIRIEGADPAQRPDIDAYCGAHAL
CCCEEEECCCCCCCCCCCHHHHHHCCCEEEEEECCEEEEECCCCCCCCCCHHHHCHHHH
DYAFVDAARKLADFGLVAMDMDSTLITIECIDEIADFCGLKAEVSAITEAAMRGEIKDFN
HHHHHHHHHHHHHCCEEEEECCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
ESLTRRVALLAGLDASALERVYEERLRLSPGAESMLAGVKAAGLKTLLVSGGFTFFTERL
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHCCCHHHHHHHH
KARLGLDFAYSNTLEIVDGKLTGKVVGEIVNADVKARAVRDTCTALGIEPARAIVLGDGS
HHHHCCEEEECCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCC
NDLKMMAAGGFSIAFRAKPVVRRAASAAFDHVGLDGLLRLF
CCEEEEEECCEEEEEECCHHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]