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The map label for this gene is leuS [H]

Identifier: 83721013

GI number: 83721013

Start: 1355685

End: 1358333

Strand: Direct

Name: leuS [H]

Synonym: BTH_I1211

Alternate gene names: 83721013

Gene position: 1355685-1358333 (Clockwise)

Preceding gene: 83719115

Following gene: 83718745

Centisome position: 35.59

GC content: 66.74

Gene sequence:

>2649_bases
GTGCGCTCGGCACCTTGCGTCGCGCGCCGCTCAAAGCCCAGCCCGAACCACACCATGCACGAAAGATACGTACCCGCCGA
CGTCGAAGCCGCCGCCCAGAGCGACTGGCGCGCAGCCGATGCCTACCGCTCGAAGGAAGACGCGAACCGCAAGAAGTTCT
ACTGCGTGTCGATGCTGCCTTACCCGTCGGGCAAGCTGCACATGGGTCACGTGCGCAACTACACGATCAACGACGTGATG
TACCGCTATCTGCGGATGAACGGCTACAACACGCTGATGCCGATGGGTTGGGACGCGTTCGGGATGCCGGCCGAGAACGC
CGCGATGGCCAACGGCGTGCCGCCCGCGCAGTGGACGTACGACAACATCGCGTACATGAAGAAGCAGATGCAGTCGATGG
GCCTCGCGATCGACTGGTCGCGCGAGGTCACGACCTGCAAGCCCGACTACTACAAGTGGAACCAGTGGCTGTTCCTGAAG
ATGCTCGAGAAGGGCATCGCGTACAAGAAGACCGGCACCGTGAACTGGGACCCGGTCGACCAGACCGTGCTCGCGAACGA
GCAGGTGATCGACGGGCGCGGCTGGCGCTCGGGCGCGCTCGTCGAGAAGCGCGAGATCCCGATGTACTACATGCGGATCA
CGCAGTACGCCGATGAACTGCTGAACGATCTCGACGGCCTCGGCTGGCCCGAGCGCGTGAAGATCATGCAGCAGAACTGG
ATCGGCAAGAGCTTCGGCGTGAACTTCGGCTTCCCGTACGAGCTCGACGGCGAGAAGAAGCTGTTGCGCGTGTTCACGAC
GCGCGCGGACACGATCATGGGCGTCACGTTCTGCGCGATCGCGGCCGAGCATCCGCTCGCCGCGCGGCTTGCGCAGGACA
AGCCGGAACTGCAGGCGTTCATCGACGAATGCAAGCGCGGCGGCGTTGCCGAGGCCGACATCGCGACGATGGAGAAGAAG
GGCGTCGCGACGGGTTTTTCGGTGTCGCATCCGCTCACGGGCGCACCGGTCGAGGTGTGGATCGGCAACTACGTGCTGAT
GAGCTACGGCGAGGGCGCGGTGATGGGCGTGCCGGCGCACGACGAGCGCGACTTCGCGTTCGCGAAGAAGTACGGCCTGC
CGATCCGGCAGGTGATTGCCGTGGAGGGCGAGACGTACTCGACCGACGCGTGGCAGGAGTGGTACGGCGACAAGACGCGC
GCCGTGTGCGTGAACAGCGGCAAGTACGACGGCCTCGCGTACGACGCGGCCGTCGACGCGATCGCGGCCGACCTGAAGGC
GGGCGGCTTCGGCGACAAGCAGATCACGTACCGCTTGCGCGACTGGGGCATTTCCCGCCAGCGCTACTGGGGCACGCCGA
TTCCGATCATCCACTGCCCGTCGTGCGGCGACGTGCCGGTGCCGGAACAGGACCTGCCCGTCGTGCTGCCGGAAGACCTC
GTGCCGGACGGCACGGGCAACCCGCTCGCGAAATCCGACGCGTTCCTGAACTGCGCGTGCCCGAAGTGCGGCGCGGCGGC
GAAGCGCGAAACGGACACGATGGACACGTTCGTCGATTCCGCGTGGTACTTCTCGCGCTACGCGGCGCCCGACGCGCAGA
CGATGGTCGACGCGCGCACCGACTACTGGATGCCGATGGACCAGTACATCGGCGGCATCGAGCACGCGATCCTGCACCTG
CTGTACTCGCGCTTCTGGGCGAAGGTGATGCGCGACCTCGGCCTCGTCGCGTTCGGCGAGCCGGCGAAGAACCTGCTCAC
GCAGGGGATGGTGCTCAACGAGACGTTCTACCGCGAGGACGCGGCGGGCAAGAAGACCTGGTACAACCCGGCCGACGTCA
CCGTGTCGTTCGACGACAAGGGGCGCCCCGTCGGCGCGGTGCTGAAGGCGGACGGGCAGCCGGTCGTGCTGGGCGGCATC
GAGAAGATGTCGAAGTCGAAGAACAACGGCGTCGATCCGCAGATGCTGATCGACCATTACGGCGCCGACACCGCGCGCCT
CTTCACGATGTTCGCGGCGCCCCCCGAGCAGCAGCTCGAGTGGTCGGGCGCGGGCGTCGACGGCGCGAGCCGCTTCCTGC
GCCGCGTGTGGGCGTTCGGCTTCGCGAACCGCGAAGCGCTCGCCGTGCGCGCGCCGTTCGACGTCGCGCAACTCGCCGAA
GCGGACAAGACGCTGCGCCGCGAGATCCACGGCGTGCTGAAGCAGGCCGATTTCGACTACCAGCGCCTGCAGTACAACAC
GGTCGTGTCGGCCGCGATGAAGATGCTCAACGCGATCGAAGGCGCGAAGGGCGCGACGCCCGCCGTGCTGCGCGAGACCT
ATGGCGTGCTGCTGCGCGTGCTGTATCCGGTCGTGCCGCACGTCACGTACGAGCTGTGGAAGGCGCTCGGCTACGCGGAC
GAGTTTGGCCCGCTTCTCGACGCGCCGTGGCCGAAGGTCGACGAGGCCGCGCTCGAGCAGGCCGAGATCGAGCTCGTGCT
GCAGATCAACGGCAAGGTGCGCGGCGCGCTGAAGGTGGCGAAGGACGCGAGCCGCGAGGCGATCGAGGCGGCGGCCGTCG
CCGACGAGATGTTCGCGAAATTCGCCGAAGGCAAGCCGGCGAAGAAGATCATTGTCGTGCCGGGCCGTCTCGTGAACGTC
GTCGTCTGA

Upstream 100 bases:

>100_bases
CCAACGGCCGTGCCGGCCGGCGCGGACGGTATAATCGACGTTTTCCCCGCGCCGCCCGCGGCCGCCGGGGAAGCGCGACT
TTCGATCCACTCGAGCGCGC

Downstream 100 bases:

>100_bases
CGGCGCGCGCGGCGGGGCTGGCATGCATCAGCAAGGAGCGAAGGTGATCCGCAGATCGTTTTTGATGCTCGTGGGCAGCG
CGGTGCTGTTGTCCGCGTGC

Product: leucyl-tRNA synthetase

Products: NA

Alternate protein names: Leucine--tRNA ligase; LeuRS [H]

Number of amino acids: Translated: 882; Mature: 882

Protein sequence:

>882_residues
MRSAPCVARRSKPSPNHTMHERYVPADVEAAAQSDWRAADAYRSKEDANRKKFYCVSMLPYPSGKLHMGHVRNYTINDVM
YRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAQWTYDNIAYMKKQMQSMGLAIDWSREVTTCKPDYYKWNQWLFLK
MLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPMYYMRITQYADELLNDLDGLGWPERVKIMQQNW
IGKSFGVNFGFPYELDGEKKLLRVFTTRADTIMGVTFCAIAAEHPLAARLAQDKPELQAFIDECKRGGVAEADIATMEKK
GVATGFSVSHPLTGAPVEVWIGNYVLMSYGEGAVMGVPAHDERDFAFAKKYGLPIRQVIAVEGETYSTDAWQEWYGDKTR
AVCVNSGKYDGLAYDAAVDAIAADLKAGGFGDKQITYRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDL
VPDGTGNPLAKSDAFLNCACPKCGAAAKRETDTMDTFVDSAWYFSRYAAPDAQTMVDARTDYWMPMDQYIGGIEHAILHL
LYSRFWAKVMRDLGLVAFGEPAKNLLTQGMVLNETFYREDAAGKKTWYNPADVTVSFDDKGRPVGAVLKADGQPVVLGGI
EKMSKSKNNGVDPQMLIDHYGADTARLFTMFAAPPEQQLEWSGAGVDGASRFLRRVWAFGFANREALAVRAPFDVAQLAE
ADKTLRREIHGVLKQADFDYQRLQYNTVVSAAMKMLNAIEGAKGATPAVLRETYGVLLRVLYPVVPHVTYELWKALGYAD
EFGPLLDAPWPKVDEAALEQAEIELVLQINGKVRGALKVAKDASREAIEAAAVADEMFAKFAEGKPAKKIIVVPGRLVNV
VV

Sequences:

>Translated_882_residues
MRSAPCVARRSKPSPNHTMHERYVPADVEAAAQSDWRAADAYRSKEDANRKKFYCVSMLPYPSGKLHMGHVRNYTINDVM
YRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAQWTYDNIAYMKKQMQSMGLAIDWSREVTTCKPDYYKWNQWLFLK
MLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPMYYMRITQYADELLNDLDGLGWPERVKIMQQNW
IGKSFGVNFGFPYELDGEKKLLRVFTTRADTIMGVTFCAIAAEHPLAARLAQDKPELQAFIDECKRGGVAEADIATMEKK
GVATGFSVSHPLTGAPVEVWIGNYVLMSYGEGAVMGVPAHDERDFAFAKKYGLPIRQVIAVEGETYSTDAWQEWYGDKTR
AVCVNSGKYDGLAYDAAVDAIAADLKAGGFGDKQITYRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDL
VPDGTGNPLAKSDAFLNCACPKCGAAAKRETDTMDTFVDSAWYFSRYAAPDAQTMVDARTDYWMPMDQYIGGIEHAILHL
LYSRFWAKVMRDLGLVAFGEPAKNLLTQGMVLNETFYREDAAGKKTWYNPADVTVSFDDKGRPVGAVLKADGQPVVLGGI
EKMSKSKNNGVDPQMLIDHYGADTARLFTMFAAPPEQQLEWSGAGVDGASRFLRRVWAFGFANREALAVRAPFDVAQLAE
ADKTLRREIHGVLKQADFDYQRLQYNTVVSAAMKMLNAIEGAKGATPAVLRETYGVLLRVLYPVVPHVTYELWKALGYAD
EFGPLLDAPWPKVDEAALEQAEIELVLQINGKVRGALKVAKDASREAIEAAAVADEMFAKFAEGKPAKKIIVVPGRLVNV
VV
>Mature_882_residues
MRSAPCVARRSKPSPNHTMHERYVPADVEAAAQSDWRAADAYRSKEDANRKKFYCVSMLPYPSGKLHMGHVRNYTINDVM
YRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAQWTYDNIAYMKKQMQSMGLAIDWSREVTTCKPDYYKWNQWLFLK
MLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPMYYMRITQYADELLNDLDGLGWPERVKIMQQNW
IGKSFGVNFGFPYELDGEKKLLRVFTTRADTIMGVTFCAIAAEHPLAARLAQDKPELQAFIDECKRGGVAEADIATMEKK
GVATGFSVSHPLTGAPVEVWIGNYVLMSYGEGAVMGVPAHDERDFAFAKKYGLPIRQVIAVEGETYSTDAWQEWYGDKTR
AVCVNSGKYDGLAYDAAVDAIAADLKAGGFGDKQITYRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDL
VPDGTGNPLAKSDAFLNCACPKCGAAAKRETDTMDTFVDSAWYFSRYAAPDAQTMVDARTDYWMPMDQYIGGIEHAILHL
LYSRFWAKVMRDLGLVAFGEPAKNLLTQGMVLNETFYREDAAGKKTWYNPADVTVSFDDKGRPVGAVLKADGQPVVLGGI
EKMSKSKNNGVDPQMLIDHYGADTARLFTMFAAPPEQQLEWSGAGVDGASRFLRRVWAFGFANREALAVRAPFDVAQLAE
ADKTLRREIHGVLKQADFDYQRLQYNTVVSAAMKMLNAIEGAKGATPAVLRETYGVLLRVLYPVVPHVTYELWKALGYAD
EFGPLLDAPWPKVDEAALEQAEIELVLQINGKVRGALKVAKDASREAIEAAAVADEMFAKFAEGKPAKKIIVVPGRLVNV
VV

Specific function: Unknown

COG id: COG0495

COG function: function code J; Leucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7661872, Length=868, Percent_Identity=36.7511520737327, Blast_Score=528, Evalue=1e-149,
Organism=Escherichia coli, GI1786861, Length=873, Percent_Identity=49.2554410080183, Blast_Score=858, Evalue=0.0,
Organism=Escherichia coli, GI1790708, Length=385, Percent_Identity=23.1168831168831, Blast_Score=90, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71997517, Length=250, Percent_Identity=42, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI71997510, Length=250, Percent_Identity=42, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI212645227, Length=351, Percent_Identity=30.4843304843305, Blast_Score=148, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6323414, Length=832, Percent_Identity=39.9038461538462, Blast_Score=565, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6321531, Length=663, Percent_Identity=22.9260935143288, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355409, Length=893, Percent_Identity=34.6024636058231, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI281366294, Length=355, Percent_Identity=22.2535211267606, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002302
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.4 [H]

Molecular weight: Translated: 98178; Mature: 98178

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAPCVARRSKPSPNHTMHERYVPADVEAAAQSDWRAADAYRSKEDANRKKFYCVSMLP
CCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCEEEEEEECC
YPSGKLHMGHVRNYTINDVMYRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAQWTY
CCCCCEEECCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHCCCCCCCCCCH
DNIAYMKKQMQSMGLAIDWSREVTTCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDPVD
HHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCC
QTVLANEQVIDGRGWRSGALVEKREIPMYYMRITQYADELLNDLDGLGWPERVKIMQQNW
CHHHCCCEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
IGKSFGVNFGFPYELDGEKKLLRVFTTRADTIMGVTFCAIAAEHPLAARLAQDKPELQAF
CCHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHH
IDECKRGGVAEADIATMEKKGVATGFSVSHPLTGAPVEVWIGNYVLMSYGEGAVMGVPAH
HHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCEEECCCC
DERDFAFAKKYGLPIRQVIAVEGETYSTDAWQEWYGDKTRAVCVNSGKYDGLAYDAAVDA
CCCCHHHHHHHCCCHHHEEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCEEHHHHHHH
IAADLKAGGFGDKQITYRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDL
HHHHHHCCCCCCCEEEEEEHHCCCCCHHCCCCCCCEEECCCCCCCCCCCCCCCEECCHHC
VPDGTGNPLAKSDAFLNCACPKCGAAAKRETDTMDTFVDSAWYFSRYAAPDAQTMVDART
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
DYWMPMDQYIGGIEHAILHLLYSRFWAKVMRDLGLVAFGEPAKNLLTQGMVLNETFYRED
CCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHCCCCCCHHHHHCC
AAGKKTWYNPADVTVSFDDKGRPVGAVLKADGQPVVLGGIEKMSKSKNNGVDPQMLIDHY
CCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCEEEEECHHHHHCCCCCCCCHHHHHHHC
GADTARLFTMFAAPPEQQLEWSGAGVDGASRFLRRVWAFGFANREALAVRAPFDVAQLAE
CCCHHHHHHHHCCCCHHHCEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
ADKTLRREIHGVLKQADFDYQRLQYNTVVSAAMKMLNAIEGAKGATPAVLRETYGVLLRV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LYPVVPHVTYELWKALGYADEFGPLLDAPWPKVDEAALEQAEIELVLQINGKVRGALKVA
HHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHCCEEEEEEECCCEEHHHHHH
KDASREAIEAAAVADEMFAKFAEGKPAKKIIVVPGRLVNVVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEC
>Mature Secondary Structure
MRSAPCVARRSKPSPNHTMHERYVPADVEAAAQSDWRAADAYRSKEDANRKKFYCVSMLP
CCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCEEEEEEECC
YPSGKLHMGHVRNYTINDVMYRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAQWTY
CCCCCEEECCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHCCCCCCCCCCH
DNIAYMKKQMQSMGLAIDWSREVTTCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDPVD
HHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCC
QTVLANEQVIDGRGWRSGALVEKREIPMYYMRITQYADELLNDLDGLGWPERVKIMQQNW
CHHHCCCEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
IGKSFGVNFGFPYELDGEKKLLRVFTTRADTIMGVTFCAIAAEHPLAARLAQDKPELQAF
CCHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHH
IDECKRGGVAEADIATMEKKGVATGFSVSHPLTGAPVEVWIGNYVLMSYGEGAVMGVPAH
HHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCEEECCCC
DERDFAFAKKYGLPIRQVIAVEGETYSTDAWQEWYGDKTRAVCVNSGKYDGLAYDAAVDA
CCCCHHHHHHHCCCHHHEEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCEEHHHHHHH
IAADLKAGGFGDKQITYRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDL
HHHHHHCCCCCCCEEEEEEHHCCCCCHHCCCCCCCEEECCCCCCCCCCCCCCCEECCHHC
VPDGTGNPLAKSDAFLNCACPKCGAAAKRETDTMDTFVDSAWYFSRYAAPDAQTMVDART
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
DYWMPMDQYIGGIEHAILHLLYSRFWAKVMRDLGLVAFGEPAKNLLTQGMVLNETFYRED
CCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHCCCCCCHHHHHCC
AAGKKTWYNPADVTVSFDDKGRPVGAVLKADGQPVVLGGIEKMSKSKNNGVDPQMLIDHY
CCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCEEEEECHHHHHCCCCCCCCHHHHHHHC
GADTARLFTMFAAPPEQQLEWSGAGVDGASRFLRRVWAFGFANREALAVRAPFDVAQLAE
CCCHHHHHHHHCCCCHHHCEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
ADKTLRREIHGVLKQADFDYQRLQYNTVVSAAMKMLNAIEGAKGATPAVLRETYGVLLRV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LYPVVPHVTYELWKALGYADEFGPLLDAPWPKVDEAALEQAEIELVLQINGKVRGALKVA
HHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHCCEEEEEEECCCEEHHHHHH
KDASREAIEAAAVADEMFAKFAEGKPAKKIIVVPGRLVNVVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA