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The map label for this gene is edd [H]

Identifier: 83720229

GI number: 83720229

Start: 1363494

End: 1365347

Strand: Direct

Name: edd [H]

Synonym: BTH_I1217

Alternate gene names: 83720229

Gene position: 1363494-1365347 (Clockwise)

Preceding gene: 83718797

Following gene: 83720852

Centisome position: 35.79

GC content: 70.17

Gene sequence:

>1854_bases
ATGGCCACGCTGCACCCCACTCTTGCGTCCGTCACCGAGCGCGTGATCGCGCGCAGCCGTCCGACCCGCCAAGCCTATCT
CGCCCGCATCGACGCCGCGCAAGGGCATTTCCCGGCGCGCGGCGCGCTGTCGTGCGCGAACCTCGCGCACGGCTTCGCGG
GCCTCGAAGGCCACGACAAGTTCGCGATCAAGGCGATCCGCGAGCCGAACATCGGCATCGTGTCGGCATACAACGAGATG
CTGTCCGCGCATGCGCCGTACAAGAGCTTTCCCGACATCATCAAGGCCGCCGCGCGCGAGCGCGGCGGCGTCGCGCAGTT
CGCGGGCGGCGTGCCGGCGATGTGCGACGGCGTCACGCAAGGCAACGCGGGGATGGAGCTGTCGCTGTTCTCGCGCGAGG
TGATCTCGATGAGCACGGCCGTTGCGCTCACGCACAACATGTTCGACGCGGCCCTTTGTCTCGGCATCTGCGACAAGATC
GTGCCCGGCCTCTTGATCGGCGCGCTGCAGTTCGGCCACCTGCCGACGATCTTCGTGCCGGCCGGCCCGATGACGAGCGG
CCTGTCGAACGACGACAAGGCGAAGATCCGCCAGCAGTTCGCGACGGGCCAGGTGGGCCGCGACGCGCTGCTCGAGGCGG
AATCGGCCGCATATCACGGCCACGGCACCTGCACGTTCTACGGCACCGCGAACAGCAACCAGATGCTGATGGAGGTGATG
GGGCTGCATCTGCCGAGCGCCGCGTTCGTCCATCCGCACACGCCGCTGCGCGACGCGCTGACGGCCGAGGCCGCGCGCCG
CGTGCTCGAGCTCACGGCCGAGCGCGGCGAGTACACGCCGATCGGCCACGTGATCGACGAGCGCGCGATCGTAAACGGGA
TCGTTGCGCTGCTCGCCACGGGCGGCTCGACGAACCACACGCTGCACCTCGTCGCGATCGCGCGCGCCGCGGGCATCCTG
ATCGACTGGGACGATTTCGACGCGCTGTCGGCCGCGGTGCCGCTCCTCGCGAAGATCTACCCGAACGGCAAGGCCGACGT
GAACCATTTCCACGCGGCGGGCGGCATCGCGTTCCTCGTGCGCAACCTGCTCGAAGGCGGCCTGCTGCACGAAGACGTGA
CGACGGTCGCGGGCAAGGGGCTTGCGCACTACACGAAGGAGCCGCGCCTGATCGACGGCGAGCTGAAGTGGGTCGACGGC
GTCGCCGTGAGCGCGGACGACAAGGTGCTGCGGCCGATCGCCGCGCCGTTCCAGCCGGACGGCGGGCTGCGCCTGATGCA
AGGCAGGCTCGGGCGCGGCGTGATCAAGATCTCGGCGGTCGCGCCCGAGCACCGCCAGGTGAAGGCTCCCGCCATCGTGT
TCGATTCGCAGGAAGCCGTGCAGGCCGCGTTCGACGCGGGCGAACTGAAGCGCGACTTCGTCGCCGTCGTGCGCTTCCAG
GGCGCGCGTGCGAACGGGATGCCGGAGCTGCACCGGCTGACGCCGCTCCTCGGCGTGCTGCAGGACCAGGGCTTTCGCGT
CGCGCTCGTGACGGACGGCCGGATGTCGGGCGCGTCGGGCAAGGTGCCGGCCGTGATCCACGTGTCGCCCGAGGCGCTGT
TGTGCGGCCCGCTCGGCAAGGTGCGCACGGGCGATACGATCGTGATCGACGCGCAAGCGGGCGTGCTCGATGTCGAGATC
GACGACGAGGCGTGGGCGGCGCGCGCGGTCGCGCAGCCCGCGCATCAGGCGGAAAACGAAGTCGGCTTCGGCCGTGAGTT
GTTCGGCGTGTTCCGCGCGGCGGCCGCGCCGGCGGAGCAGGGCGCGTCGGTGTTCGGCGCGTTGGTGGGCGAAACGGCCC
ACGTCACCGCATAA

Upstream 100 bases:

>100_bases
GTAGTTTTTCTACTAAACTCGCGCCGTTCGTCCGACGACACGGACGTCCCCACGATTCCAGCTTGCCGGCCTCGTCCGGC
TCATGTGAGGAGCGCCCAGC

Downstream 100 bases:

>100_bases
GCGAAAAGGAGTTGCATTGATGAAGACGATTGGCGAGATCGTGAAGCTGGGCCCGGTGATTCCGGTGCTCGCGTTCGATT
CGGTCGAACAGGGCGAACAG

Product: phosphogluconate dehydratase

Products: NA

Alternate protein names: 6-phosphogluconate dehydratase [H]

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MATLHPTLASVTERVIARSRPTRQAYLARIDAAQGHFPARGALSCANLAHGFAGLEGHDKFAIKAIREPNIGIVSAYNEM
LSAHAPYKSFPDIIKAAARERGGVAQFAGGVPAMCDGVTQGNAGMELSLFSREVISMSTAVALTHNMFDAALCLGICDKI
VPGLLIGALQFGHLPTIFVPAGPMTSGLSNDDKAKIRQQFATGQVGRDALLEAESAAYHGHGTCTFYGTANSNQMLMEVM
GLHLPSAAFVHPHTPLRDALTAEAARRVLELTAERGEYTPIGHVIDERAIVNGIVALLATGGSTNHTLHLVAIARAAGIL
IDWDDFDALSAAVPLLAKIYPNGKADVNHFHAAGGIAFLVRNLLEGGLLHEDVTTVAGKGLAHYTKEPRLIDGELKWVDG
VAVSADDKVLRPIAAPFQPDGGLRLMQGRLGRGVIKISAVAPEHRQVKAPAIVFDSQEAVQAAFDAGELKRDFVAVVRFQ
GARANGMPELHRLTPLLGVLQDQGFRVALVTDGRMSGASGKVPAVIHVSPEALLCGPLGKVRTGDTIVIDAQAGVLDVEI
DDEAWAARAVAQPAHQAENEVGFGRELFGVFRAAAAPAEQGASVFGALVGETAHVTA

Sequences:

>Translated_617_residues
MATLHPTLASVTERVIARSRPTRQAYLARIDAAQGHFPARGALSCANLAHGFAGLEGHDKFAIKAIREPNIGIVSAYNEM
LSAHAPYKSFPDIIKAAARERGGVAQFAGGVPAMCDGVTQGNAGMELSLFSREVISMSTAVALTHNMFDAALCLGICDKI
VPGLLIGALQFGHLPTIFVPAGPMTSGLSNDDKAKIRQQFATGQVGRDALLEAESAAYHGHGTCTFYGTANSNQMLMEVM
GLHLPSAAFVHPHTPLRDALTAEAARRVLELTAERGEYTPIGHVIDERAIVNGIVALLATGGSTNHTLHLVAIARAAGIL
IDWDDFDALSAAVPLLAKIYPNGKADVNHFHAAGGIAFLVRNLLEGGLLHEDVTTVAGKGLAHYTKEPRLIDGELKWVDG
VAVSADDKVLRPIAAPFQPDGGLRLMQGRLGRGVIKISAVAPEHRQVKAPAIVFDSQEAVQAAFDAGELKRDFVAVVRFQ
GARANGMPELHRLTPLLGVLQDQGFRVALVTDGRMSGASGKVPAVIHVSPEALLCGPLGKVRTGDTIVIDAQAGVLDVEI
DDEAWAARAVAQPAHQAENEVGFGRELFGVFRAAAAPAEQGASVFGALVGETAHVTA
>Mature_616_residues
ATLHPTLASVTERVIARSRPTRQAYLARIDAAQGHFPARGALSCANLAHGFAGLEGHDKFAIKAIREPNIGIVSAYNEML
SAHAPYKSFPDIIKAAARERGGVAQFAGGVPAMCDGVTQGNAGMELSLFSREVISMSTAVALTHNMFDAALCLGICDKIV
PGLLIGALQFGHLPTIFVPAGPMTSGLSNDDKAKIRQQFATGQVGRDALLEAESAAYHGHGTCTFYGTANSNQMLMEVMG
LHLPSAAFVHPHTPLRDALTAEAARRVLELTAERGEYTPIGHVIDERAIVNGIVALLATGGSTNHTLHLVAIARAAGILI
DWDDFDALSAAVPLLAKIYPNGKADVNHFHAAGGIAFLVRNLLEGGLLHEDVTTVAGKGLAHYTKEPRLIDGELKWVDGV
AVSADDKVLRPIAAPFQPDGGLRLMQGRLGRGVIKISAVAPEHRQVKAPAIVFDSQEAVQAAFDAGELKRDFVAVVRFQG
ARANGMPELHRLTPLLGVLQDQGFRVALVTDGRMSGASGKVPAVIHVSPEALLCGPLGKVRTGDTIVIDAQAGVLDVEID
DEAWAARAVAQPAHQAENEVGFGRELFGVFRAAAAPAEQGASVFGALVGETAHVTA

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. [C]

COG id: COG0129

COG function: function code EG; Dihydroxyacid dehydratase/phosphogluconate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ilvD/edd family [H]

Homologues:

Organism=Escherichia coli, GI1788157, Length=602, Percent_Identity=59.1362126245847, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI48994964, Length=582, Percent_Identity=28.6941580756014, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI2367371, Length=506, Percent_Identity=30.4347826086957, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786464, Length=498, Percent_Identity=31.7269076305221, Blast_Score=146, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322476, Length=529, Percent_Identity=28.9224952741021, Blast_Score=194, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004786
- InterPro:   IPR015928
- InterPro:   IPR000581
- InterPro:   IPR020558 [H]

Pfam domain/function: PF00920 ILVD_EDD [H]

EC number: =4.2.1.12 [H]

Molecular weight: Translated: 64888; Mature: 64757

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00886 ILVD_EDD_1 ; PS00887 ILVD_EDD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLHPTLASVTERVIARSRPTRQAYLARIDAAQGHFPARGALSCANLAHGFAGLEGHDK
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
FAIKAIREPNIGIVSAYNEMLSAHAPYKSFPDIIKAAARERGGVAQFAGGVPAMCDGVTQ
EEEEEECCCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCHHHCCCCC
GNAGMELSLFSREVISMSTAVALTHNMFDAALCLGICDKIVPGLLIGALQFGHLPTIFVP
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGPMTSGLSNDDKAKIRQQFATGQVGRDALLEAESAAYHGHGTCTFYGTANSNQMLMEVM
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCEECCCEEEEEEECCCCCHHHHHHH
GLHLPSAAFVHPHTPLRDALTAEAARRVLELTAERGEYTPIGHVIDERAIVNGIVALLAT
HCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
GGSTNHTLHLVAIARAAGILIDWDDFDALSAAVPLLAKIYPNGKADVNHFHAAGGIAFLV
CCCCCCEEEEEEEHHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RNLLEGGLLHEDVTTVAGKGLAHYTKEPRLIDGELKWVDGVAVSADDKVLRPIAAPFQPD
HHHHCCCCCHHHHHHHHCCCHHHHCCCCCEECCCEEEECCEEECCCCHHHHHHCCCCCCC
GGLRLMQGRLGRGVIKISAVAPEHRQVKAPAIVFDSQEAVQAAFDAGELKRDFVAVVRFQ
CCCEEECCCCCCCEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHEEC
GARANGMPELHRLTPLLGVLQDQGFRVALVTDGRMSGASGKVPAVIHVSPEALLCGPLGK
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEECCCEEEECCCCC
VRTGDTIVIDAQAGVLDVEIDDEAWAARAVAQPAHQAENEVGFGRELFGVFRAAAAPAEQ
CCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHH
GASVFGALVGETAHVTA
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ATLHPTLASVTERVIARSRPTRQAYLARIDAAQGHFPARGALSCANLAHGFAGLEGHDK
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
FAIKAIREPNIGIVSAYNEMLSAHAPYKSFPDIIKAAARERGGVAQFAGGVPAMCDGVTQ
EEEEEECCCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCHHHCCCCC
GNAGMELSLFSREVISMSTAVALTHNMFDAALCLGICDKIVPGLLIGALQFGHLPTIFVP
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGPMTSGLSNDDKAKIRQQFATGQVGRDALLEAESAAYHGHGTCTFYGTANSNQMLMEVM
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCEECCCEEEEEEECCCCCHHHHHHH
GLHLPSAAFVHPHTPLRDALTAEAARRVLELTAERGEYTPIGHVIDERAIVNGIVALLAT
HCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
GGSTNHTLHLVAIARAAGILIDWDDFDALSAAVPLLAKIYPNGKADVNHFHAAGGIAFLV
CCCCCCEEEEEEEHHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RNLLEGGLLHEDVTTVAGKGLAHYTKEPRLIDGELKWVDGVAVSADDKVLRPIAAPFQPD
HHHHCCCCCHHHHHHHHCCCHHHHCCCCCEECCCEEEECCEEECCCCHHHHHHCCCCCCC
GGLRLMQGRLGRGVIKISAVAPEHRQVKAPAIVFDSQEAVQAAFDAGELKRDFVAVVRFQ
CCCEEECCCCCCCEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHEEC
GARANGMPELHRLTPLLGVLQDQGFRVALVTDGRMSGASGKVPAVIHVSPEALLCGPLGK
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEECCCEEEECCCCC
VRTGDTIVIDAQAGVLDVEIDDEAWAARAVAQPAHQAENEVGFGRELFGVFRAAAAPAEQ
CCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHH
GASVFGALVGETAHVTA
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]