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The map label for this gene is cyaA [H]

Identifier: 83720215

GI number: 83720215

Start: 2002813

End: 2004825

Strand: Reverse

Name: cyaA [H]

Synonym: BTH_I1787

Alternate gene names: 83720215

Gene position: 2004825-2002813 (Counterclockwise)

Preceding gene: 83721169

Following gene: 83719897

Centisome position: 52.63

GC content: 63.54

Gene sequence:

>2013_bases
ATGTTCGGTAAATTGACGCTTTCGGCGATCCCGTTCGATCAGCCGATCATCATGGGCGCGGCCGCGCTCATGGCGCTCGT
CGCGCTGTCTGTCGTCGGCGCGCTCACCTACACGAAGCGCTGGAAATGGCTGTGGTGCGAATGGCTCACGTCGGTCGACC
ACAAGAAGATCGGCGTGATGTACATCGTCGTCGCGGTGCTGATGCTGCTGCGCGGCTTCGCGGACGCGGTGATGATGCGC
CTGCAGCTCGCGCTCGCGTACAACGGCCCCGGCTATCTGCCGCCGCACCACTACGATCAGATCTTCACCGCGCACGGCGT
CATCATGATCTTCTTCATGGCGATGGCGCTCCTCGTCGGGCTCTTCAACCTGATCGTGCCGCTGCAGATCGGCGCGCGCG
ACGTCGCGTTCCCGTTCCTCAATTCGCTGAGCTTCTGGATGACGGCCGTCGCTGCGCTGCTGATGAACGTGTCGCTCGTC
GTCGGCGAGTTCGCGCAGACGGGCTGGCTCGCGTATCCGCCGCTGTCGGAGCTGCAGTTCAGCCCGGGCGTGGGCGTCGA
CTACTATCTGTGGGCGCTGCAGATATCCGGCGTCGGCACGCTGATCACCGCGATCAACTTCTTCGTGACGATCATCCGGA
TGCGCGCGCCCGGCATGACGCTGATGAAGATGCCCGTGTTCACGTGGACCGCGCTCTGCTCGAACGTCCTCATCATGGCG
ACGTTCCCGATTCTCACGGTCGCGCTCGCCCTCCTCGCGCTCGACCGCTACCTCGGCATGCACTTCTTCACGAACGACGC
CGGCGGCAACGCGATGGTGTATCTGAACCTGATCTGGGCGTGGGGTCATCCGGAGGTGTACATCCTCGTGCTGCCCGCGT
TCGGCATCTATTCGGAAGTGATCGCGACGTTCTCGAAGAAGCCGCTGTTCGGCTACAAGACGATGGTGTACGCCTCATGC
GTGATCATGGTGCTCGCGTTCCTCGTGTGGCTGCACCACTTCTTCACGATGGGCTCGGGCGCGAACGTGAACGCGTTCTT
CGGGATCATGACGATGGTGATCGCGATTCCGACCGGCGTGAAGATCTTCAACTGGCTGTTTACGATGTATCGCGGCCGCA
TCGAGTTCACCGCGCCCGTGCTGTGGACGATCGGCTTCATGGTGACGTTCACGCTCGGCGGGATGACGGGCGTGATGATG
GCGATTCCCGGCGCGGACTTCGTGCTGCACAACAGCCTGTTCCTGATCGCGCACTTCCACAACGCGATCATCGGCGGCGT
GGTGTTCGGCTATCTCGCCGGCTTTCACTACTGGTTCCCGAAGGCGTTCGGCTTCAAGCTCGACGAGAAGCTCGGCAAGC
GCGCGTTCTGGTTCTGGTTCATCGGCTTCTACGTGTCGTTCGTGCCGCTTTACGTGCTCGGCTTCATGGGGATGACGCGC
CGCCTGAATCATTATGACAACCCCGCCTGGCATCCGTGGCTCATCGTCGCCGCGTGCGGCGTCGCGCTGATCGCGATCGG
CGTGCTGCATCAGGTCGCTCAGGTCTGGGTTGCGGTGCGCAAGCGCAACGAGCCCGGCTACCTCGACACGACGGGCGACC
CGTGGAACGGCCGCACGCTCGAATGGGCGACGTCGTCGCCGCCGCCCGTCTACAACTTCGCGGTGATCCCGACCGTGCAC
GCGCTCGACGAGCTCGCGTACCGCAAGGAGCACGGCCTCGATGTCGGCAACGGCCGGAAGATCGTCTATCAGGACATCCA
CATGCCGTCGAATACGGGCGCGGGCTTCGTCATCGGCATGCTCAGCCTCGTGCTCGGCTTCGCGCTCGTATGGCACATCT
GGTGGCTCGCGATCGCATCGTTCGCCGGCATCGTCGCGACGGTGATCCTGTACAGCGCGGGCGACAACGACGGCTATTAC
ATCCCGGCCGAAACGGTCCGCAAGATCGAGGAGAAGCGCGCCGGCGCGCGCATGCCGGCGCAGCCGGCCGAAGTCGAACT
GGAGGTCAACTGA

Upstream 100 bases:

>100_bases
GACGGTCGACTCGCGGCTCTTTCACAACATCATCGCGAAGTACAACAACGGTCACGTCCTCGATCTGACGGACGCCGCCT
GTCGGACGAAGAGGTAATGC

Downstream 100 bases:

>100_bases
TGTCGCACAACACGATGATGCTCGACCACGCGGCATCTCACGATCACCCGCCGTCGCATTCGGTGTTCGGCTTCTGGCTG
TACCTGATGACCGACTGCGT

Product: ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome A1 subunit 1; Oxidase BA(3) subunit 1; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MFGKLTLSAIPFDQPIIMGAAALMALVALSVVGALTYTKRWKWLWCEWLTSVDHKKIGVMYIVVAVLMLLRGFADAVMMR
LQLALAYNGPGYLPPHHYDQIFTAHGVIMIFFMAMALLVGLFNLIVPLQIGARDVAFPFLNSLSFWMTAVAALLMNVSLV
VGEFAQTGWLAYPPLSELQFSPGVGVDYYLWALQISGVGTLITAINFFVTIIRMRAPGMTLMKMPVFTWTALCSNVLIMA
TFPILTVALALLALDRYLGMHFFTNDAGGNAMVYLNLIWAWGHPEVYILVLPAFGIYSEVIATFSKKPLFGYKTMVYASC
VIMVLAFLVWLHHFFTMGSGANVNAFFGIMTMVIAIPTGVKIFNWLFTMYRGRIEFTAPVLWTIGFMVTFTLGGMTGVMM
AIPGADFVLHNSLFLIAHFHNAIIGGVVFGYLAGFHYWFPKAFGFKLDEKLGKRAFWFWFIGFYVSFVPLYVLGFMGMTR
RLNHYDNPAWHPWLIVAACGVALIAIGVLHQVAQVWVAVRKRNEPGYLDTTGDPWNGRTLEWATSSPPPVYNFAVIPTVH
ALDELAYRKEHGLDVGNGRKIVYQDIHMPSNTGAGFVIGMLSLVLGFALVWHIWWLAIASFAGIVATVILYSAGDNDGYY
IPAETVRKIEEKRAGARMPAQPAEVELEVN

Sequences:

>Translated_670_residues
MFGKLTLSAIPFDQPIIMGAAALMALVALSVVGALTYTKRWKWLWCEWLTSVDHKKIGVMYIVVAVLMLLRGFADAVMMR
LQLALAYNGPGYLPPHHYDQIFTAHGVIMIFFMAMALLVGLFNLIVPLQIGARDVAFPFLNSLSFWMTAVAALLMNVSLV
VGEFAQTGWLAYPPLSELQFSPGVGVDYYLWALQISGVGTLITAINFFVTIIRMRAPGMTLMKMPVFTWTALCSNVLIMA
TFPILTVALALLALDRYLGMHFFTNDAGGNAMVYLNLIWAWGHPEVYILVLPAFGIYSEVIATFSKKPLFGYKTMVYASC
VIMVLAFLVWLHHFFTMGSGANVNAFFGIMTMVIAIPTGVKIFNWLFTMYRGRIEFTAPVLWTIGFMVTFTLGGMTGVMM
AIPGADFVLHNSLFLIAHFHNAIIGGVVFGYLAGFHYWFPKAFGFKLDEKLGKRAFWFWFIGFYVSFVPLYVLGFMGMTR
RLNHYDNPAWHPWLIVAACGVALIAIGVLHQVAQVWVAVRKRNEPGYLDTTGDPWNGRTLEWATSSPPPVYNFAVIPTVH
ALDELAYRKEHGLDVGNGRKIVYQDIHMPSNTGAGFVIGMLSLVLGFALVWHIWWLAIASFAGIVATVILYSAGDNDGYY
IPAETVRKIEEKRAGARMPAQPAEVELEVN
>Mature_670_residues
MFGKLTLSAIPFDQPIIMGAAALMALVALSVVGALTYTKRWKWLWCEWLTSVDHKKIGVMYIVVAVLMLLRGFADAVMMR
LQLALAYNGPGYLPPHHYDQIFTAHGVIMIFFMAMALLVGLFNLIVPLQIGARDVAFPFLNSLSFWMTAVAALLMNVSLV
VGEFAQTGWLAYPPLSELQFSPGVGVDYYLWALQISGVGTLITAINFFVTIIRMRAPGMTLMKMPVFTWTALCSNVLIMA
TFPILTVALALLALDRYLGMHFFTNDAGGNAMVYLNLIWAWGHPEVYILVLPAFGIYSEVIATFSKKPLFGYKTMVYASC
VIMVLAFLVWLHHFFTMGSGANVNAFFGIMTMVIAIPTGVKIFNWLFTMYRGRIEFTAPVLWTIGFMVTFTLGGMTGVMM
AIPGADFVLHNSLFLIAHFHNAIIGGVVFGYLAGFHYWFPKAFGFKLDEKLGKRAFWFWFIGFYVSFVPLYVLGFMGMTR
RLNHYDNPAWHPWLIVAACGVALIAIGVLHQVAQVWVAVRKRNEPGYLDTTGDPWNGRTLEWATSSPPPVYNFAVIPTVH
ALDELAYRKEHGLDVGNGRKIVYQDIHMPSNTGAGFVIGMLSLVLGFALVWHIWWLAIASFAGIVATVILYSAGDNDGYY
IPAETVRKIEEKRAGARMPAQPAEVELEVN

Specific function: Catalytic subunit of the enzyme. Electrons originating in a quinol are transferred to the bimetallic center formed by heme a and copper B [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=509, Percent_Identity=39.4891944990177, Blast_Score=345, Evalue=7e-95,
Organism=Escherichia coli, GI1786634, Length=654, Percent_Identity=66.5137614678899, Blast_Score=906, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=539, Percent_Identity=37.847866419295, Blast_Score=354, Evalue=2e-98,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=42.7692307692308, Blast_Score=254, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6226523, Length=246, Percent_Identity=34.9593495934959, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74596; Mature: 74596

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLTLSAIPFDQPIIMGAAALMALVALSVVGALTYTKRWKWLWCEWLTSVDHKKIGVM
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
YIVVAVLMLLRGFADAVMMRLQLALAYNGPGYLPPHHYDQIFTAHGVIMIFFMAMALLVG
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LFNLIVPLQIGARDVAFPFLNSLSFWMTAVAALLMNVSLVVGEFAQTGWLAYPPLSELQF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHCCC
SPGVGVDYYLWALQISGVGTLITAINFFVTIIRMRAPGMTLMKMPVFTWTALCSNVLIMA
CCCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHH
TFPILTVALALLALDRYLGMHFFTNDAGGNAMVYLNLIWAWGHPEVYILVLPAFGIYSEV
HHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEECCCCCEEEEEECCHHHHHHH
IATFSKKPLFGYKTMVYASCVIMVLAFLVWLHHFFTMGSGANVNAFFGIMTMVIAIPTGV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCH
KIFNWLFTMYRGRIEFTAPVLWTIGFMVTFTLGGMTGVMMAIPGADFVLHNSLFLIAHFH
HHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEHHCCCCEEHHHH
NAIIGGVVFGYLAGFHYWFPKAFGFKLDEKLGKRAFWFWFIGFYVSFVPLYVLGFMGMTR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLNHYDNPAWHPWLIVAACGVALIAIGVLHQVAQVWVAVRKRNEPGYLDTTGDPWNGRTL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
EWATSSPPPVYNFAVIPTVHALDELAYRKEHGLDVGNGRKIVYQDIHMPSNTGAGFVIGM
EECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHH
LSLVLGFALVWHIWWLAIASFAGIVATVILYSAGDNDGYYIPAETVRKIEEKRAGARMPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHCCCCCCC
QPAEVELEVN
CCCCEEEEEC
>Mature Secondary Structure
MFGKLTLSAIPFDQPIIMGAAALMALVALSVVGALTYTKRWKWLWCEWLTSVDHKKIGVM
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
YIVVAVLMLLRGFADAVMMRLQLALAYNGPGYLPPHHYDQIFTAHGVIMIFFMAMALLVG
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LFNLIVPLQIGARDVAFPFLNSLSFWMTAVAALLMNVSLVVGEFAQTGWLAYPPLSELQF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHCCC
SPGVGVDYYLWALQISGVGTLITAINFFVTIIRMRAPGMTLMKMPVFTWTALCSNVLIMA
CCCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHH
TFPILTVALALLALDRYLGMHFFTNDAGGNAMVYLNLIWAWGHPEVYILVLPAFGIYSEV
HHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEECCCCCEEEEEECCHHHHHHH
IATFSKKPLFGYKTMVYASCVIMVLAFLVWLHHFFTMGSGANVNAFFGIMTMVIAIPTGV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCH
KIFNWLFTMYRGRIEFTAPVLWTIGFMVTFTLGGMTGVMMAIPGADFVLHNSLFLIAHFH
HHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEHHCCCCEEHHHH
NAIIGGVVFGYLAGFHYWFPKAFGFKLDEKLGKRAFWFWFIGFYVSFVPLYVLGFMGMTR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLNHYDNPAWHPWLIVAACGVALIAIGVLHQVAQVWVAVRKRNEPGYLDTTGDPWNGRTL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
EWATSSPPPVYNFAVIPTVHALDELAYRKEHGLDVGNGRKIVYQDIHMPSNTGAGFVIGM
EECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHH
LSLVLGFALVWHIWWLAIASFAGIVATVILYSAGDNDGYYIPAETVRKIEEKRAGARMPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHCCCCCCC
QPAEVELEVN
CCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8392509 [H]