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The map label for this gene is mdtA [H]

Identifier: 83719695

GI number: 83719695

Start: 2201638

End: 2202954

Strand: Reverse

Name: mdtA [H]

Synonym: BTH_I1951

Alternate gene names: 83719695

Gene position: 2202954-2201638 (Counterclockwise)

Preceding gene: 83718759

Following gene: 83720314

Centisome position: 57.83

GC content: 70.99

Gene sequence:

>1317_bases
TTGCGCCCGAACATACCTCCGTCCGTTCACCGACGCCGACATCGCGCCGCGATGCCGGCCGCATCCATTTGTACGCCAAC
CCGCATGCCCATGCCTTTTGTCACACGCCGTCAACTCGTTGCGCTCGCACTGATATCGCTCGTCGCGATCACGCTTGCCG
CGTGGCTCGCCAAACCTTCAGCCGACGCGCGCGCCGCCGCCGCGAAGCAGGCCGACGCCGCGATTCCCGTCACGGCGGCC
GTCGTCGGCACGATGAACCTGCCCGTCTACCTGACCGGGGTCGGCTCCGTCACGCCGCAGTACGACGTGACCGTGCGGAG
CCAGGTCGACGGCCAGATCACGAGCGTGCGGTTCCGGGAAGGCCAGCACGTGCATGCGGGCGACGTGCTCATCGAGATCG
ACCGCCGGGCGCTCCAGGCAGCCGCCGATCAGGCCGCCGCGAAGCTCGAGCAAGACAAGGCGACGCTCGCGAACGCCCGG
CTCGAGCTCGAGCGCCATCAGCGGCTTGCCGAAGTGAACGCGGCGCCGAAGCAGATGCTGGATACGTGGAAGGCGCGCGT
CGACGAACTGCACGCACAGATTCGCGGCGACCAGGCCGCCGTGCAGAACGCCCGCGTGGCCGTCGATTACACGACGATCC
GAGCGCCCATCTCCGGGCGCGTCGGGTTTCGGCTCGTCGACCAGGGCAACCTCGTGAAGGCCAACGACACCGCGCTGCTC
ACGCTCGTCACGACCTCGCCGATCACCGCGATCTATTCCCAATCGCAGGACGCGCTGCCGGCGATCCAGGCGGCGCTGCG
GCGCGGCGCGGTCGAGGCCGTCGCGCTGAGCACGGACGGCGCGGCGGTGCTGTCGCACGGACGCCTGAGCACGATCGAGA
ACCGCGTCGATCCGGGCAGCGGCGTGGTCCGGATGAAAGCGGTGTTCGAGAATGCCGACGGCGCGCTGTGGCCGGGACAG
TCGGTGATGATCCGCACCGTCGTCGACGTGCTGCGAAACGCGACGGCGGTGCCGGAGGACGCGATCCAGATCGGGCCGGA
CGGCAGCTTCGTCTACGTGATCGGCGCCGGCGACAAGGTCGCGGTGCGGCCGGTCCAGGTATCGCATCGGGTGCACGGCT
ACACGGCCGTCGCGAACGGCCTGCGCGCCGGTGAGCGCGTCGTCGTGCAGGGCCAGTACCGGCTGCAGGACGGCGCGCGC
GTCGCCGCGACGATGATGCCGGCGCGCGACGATGACGCCGGCGCGACGGGCGACGGCGCGCGGGCGGCGGGCCGCGAAGC
GGCGGCCGCGGCCGCGACGGACGCGCACCGATCATGA

Upstream 100 bases:

>100_bases
GCTTGCCGGCGCGCGCGTCGAACGGCGCCGGGCGAACCCGCAACGCCCGGCCTCCGATCCCCGTTCGGCCGGCGCCATCA
CGTCGCCCCGGCCGTGACGC

Downstream 100 bases:

>100_bases
GCAAGAACCTGTTCGCGGTGTTCATCCGCTACCCGGTCGCCACCTGCCTGATGACGGCGGGCATCCTGTTCGCGGGCGTG
GCCGCGTATTTCCATTTGCC

Product: multidrug efflux RND membrane fusion protein MexE

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MRPNIPPSVHRRRHRAAMPAASICTPTRMPMPFVTRRQLVALALISLVAITLAAWLAKPSADARAAAAKQADAAIPVTAA
VVGTMNLPVYLTGVGSVTPQYDVTVRSQVDGQITSVRFREGQHVHAGDVLIEIDRRALQAAADQAAAKLEQDKATLANAR
LELERHQRLAEVNAAPKQMLDTWKARVDELHAQIRGDQAAVQNARVAVDYTTIRAPISGRVGFRLVDQGNLVKANDTALL
TLVTTSPITAIYSQSQDALPAIQAALRRGAVEAVALSTDGAAVLSHGRLSTIENRVDPGSGVVRMKAVFENADGALWPGQ
SVMIRTVVDVLRNATAVPEDAIQIGPDGSFVYVIGAGDKVAVRPVQVSHRVHGYTAVANGLRAGERVVVQGQYRLQDGAR
VAATMMPARDDDAGATGDGARAAGREAAAAAATDAHRS

Sequences:

>Translated_438_residues
MRPNIPPSVHRRRHRAAMPAASICTPTRMPMPFVTRRQLVALALISLVAITLAAWLAKPSADARAAAAKQADAAIPVTAA
VVGTMNLPVYLTGVGSVTPQYDVTVRSQVDGQITSVRFREGQHVHAGDVLIEIDRRALQAAADQAAAKLEQDKATLANAR
LELERHQRLAEVNAAPKQMLDTWKARVDELHAQIRGDQAAVQNARVAVDYTTIRAPISGRVGFRLVDQGNLVKANDTALL
TLVTTSPITAIYSQSQDALPAIQAALRRGAVEAVALSTDGAAVLSHGRLSTIENRVDPGSGVVRMKAVFENADGALWPGQ
SVMIRTVVDVLRNATAVPEDAIQIGPDGSFVYVIGAGDKVAVRPVQVSHRVHGYTAVANGLRAGERVVVQGQYRLQDGAR
VAATMMPARDDDAGATGDGARAAGREAAAAAATDAHRS
>Mature_438_residues
MRPNIPPSVHRRRHRAAMPAASICTPTRMPMPFVTRRQLVALALISLVAITLAAWLAKPSADARAAAAKQADAAIPVTAA
VVGTMNLPVYLTGVGSVTPQYDVTVRSQVDGQITSVRFREGQHVHAGDVLIEIDRRALQAAADQAAAKLEQDKATLANAR
LELERHQRLAEVNAAPKQMLDTWKARVDELHAQIRGDQAAVQNARVAVDYTTIRAPISGRVGFRLVDQGNLVKANDTALL
TLVTTSPITAIYSQSQDALPAIQAALRRGAVEAVALSTDGAAVLSHGRLSTIENRVDPGSGVVRMKAVFENADGALWPGQ
SVMIRTVVDVLRNATAVPEDAIQIGPDGSFVYVIGAGDKVAVRPVQVSHRVHGYTAVANGLRAGERVVVQGQYRLQDGAR
VAATMMPARDDDAGATGDGARAAGREAAAAAATDAHRS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=369, Percent_Identity=38.2113821138211, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1786668, Length=380, Percent_Identity=31.3157894736842, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789929, Length=315, Percent_Identity=29.2063492063492, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789665, Length=337, Percent_Identity=28.486646884273, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081951, Length=186, Percent_Identity=30.1075268817204, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46282; Mature: 46282

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPNIPPSVHRRRHRAAMPAASICTPTRMPMPFVTRRQLVALALISLVAITLAAWLAKPS
CCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ADARAAAAKQADAAIPVTAAVVGTMNLPVYLTGVGSVTPQYDVTVRSQVDGQITSVRFRE
CCHHHHHHHHCCCCCCCHHHEEEECCCCEEEEECCCCCCCEEEEEECCCCCCEEEEEECC
GQHVHAGDVLIEIDRRALQAAADQAAAKLEQDKATLANARLELERHQRLAEVNAAPKQML
CCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
DTWKARVDELHAQIRGDQAAVQNARVAVDYTTIRAPISGRVGFRLVDQGNLVKANDTALL
HHHHHHHHHHHHHHCCCHHHHCCCEEEEEEEEEECCCCCCCCEEEECCCCEEEECCCEEE
TLVTTSPITAIYSQSQDALPAIQAALRRGAVEAVALSTDGAAVLSHGRLSTIENRVDPGS
EEEECCCHHHHHCCCCCCHHHHHHHHHCCCEEEEEEECCCHHHHCCCCHHHHHHCCCCCC
GVVRMKAVFENADGALWPGQSVMIRTVVDVLRNATAVPEDAIQIGPDGSFVYVIGAGDKV
CEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEEECCCEE
AVRPVQVSHRVHGYTAVANGLRAGERVVVQGQYRLQDGARVAATMMPARDDDAGATGDGA
EEEEEEEHHHHCCHHHHHHHCCCCCEEEEEECEEECCCCEEEEEECCCCCCCCCCCCCCC
RAAGREAAAAAATDAHRS
HHCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRPNIPPSVHRRRHRAAMPAASICTPTRMPMPFVTRRQLVALALISLVAITLAAWLAKPS
CCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ADARAAAAKQADAAIPVTAAVVGTMNLPVYLTGVGSVTPQYDVTVRSQVDGQITSVRFRE
CCHHHHHHHHCCCCCCCHHHEEEECCCCEEEEECCCCCCCEEEEEECCCCCCEEEEEECC
GQHVHAGDVLIEIDRRALQAAADQAAAKLEQDKATLANARLELERHQRLAEVNAAPKQML
CCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
DTWKARVDELHAQIRGDQAAVQNARVAVDYTTIRAPISGRVGFRLVDQGNLVKANDTALL
HHHHHHHHHHHHHHCCCHHHHCCCEEEEEEEEEECCCCCCCCEEEECCCCEEEECCCEEE
TLVTTSPITAIYSQSQDALPAIQAALRRGAVEAVALSTDGAAVLSHGRLSTIENRVDPGS
EEEECCCHHHHHCCCCCCHHHHHHHHHCCCEEEEEEECCCHHHHCCCCHHHHHHCCCCCC
GVVRMKAVFENADGALWPGQSVMIRTVVDVLRNATAVPEDAIQIGPDGSFVYVIGAGDKV
CEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEEECCCEE
AVRPVQVSHRVHGYTAVANGLRAGERVVVQGQYRLQDGARVAATMMPARDDDAGATGDGA
EEEEEEEHHHHCCHHHHHHHCCCCCEEEEEECEEECCCCEEEEEECCCCCCCCCCCCCCC
RAAGREAAAAAATDAHRS
HHCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA