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The map label for this gene is kdsA-1 [H]

Identifier: 83719323

GI number: 83719323

Start: 1538756

End: 1539601

Strand: Direct

Name: kdsA-1 [H]

Synonym: BTH_I1360

Alternate gene names: 83719323

Gene position: 1538756-1539601 (Clockwise)

Preceding gene: 83720315

Following gene: 83719096

Centisome position: 40.4

GC content: 65.48

Gene sequence:

>846_bases
ATGAACGTAGCAATCAGCCCCGGCATCACGGCCGGCAACGACCGGCCTTTCGTGCTGTTCGGCGGGATCAACGTGCTCGA
GAGTCTCGACTTCACGCTCGAGGTGTGCAGCGAATACGCCGCGGTGACGCGCAAGCTCGGCATTCCGTTCGTGTTCAAGG
CGTCGTTCGACAAGGCGAACCGCTCGTCGATTCATTCGTATCGCGGCGTCGGGCTCGACGAAGGCCTGAAGATTCTCGCC
GAGGTGAAGGCGCGCTTCGGCGTGCCGGTGATCACCGACGTGCACGAGGTCGAACAGGCCGCACCCGTCGCCGAAGTCGC
CGACGTGCTGCAGGTGCCTGCGTTTCTCGCGCGGCAGACCGATCTCGTCGTCGCGATCGCGAAGGCGGCCAAGCCGGTGA
ATGTGAAGAAGCCGCAGTTCATGAGCCCGACGCAGGTGAAGCACGTGGTGTCCAAATGTCTCGAAGCCGGCAACGATCGC
GTGATGCTGTGCGAGCGCGGCAGCTCGTTCGGTTACGACAATCTCGTCGTCGACATGCTCGGCTTCCGGCAGATGGCCGA
GGCGACAGGCGGCTGCCCGGTGATCTTCGACGTCACGCACAGCCTGCAATGCCGCGATCCGCTCGGCGAGGCGTCGGGCG
GCCGGCGTCGGCAAGTGCTCGATCTCGCGCGTGCGGGCGTCGCGGTCGGCATCGCCGGGCTCTTTGTCGAAGCGCATCCC
GATCCCGAGCGCGCGCGCTGCGACGGGCCGAGCGCGCTGCCGCTGCCTCTGCTCGAAGGTTTTCTGTCGCAGATGAAGGC
GATCGACGATCTCGTCAAGCGCATGCCGGCGCTCGACATTCGATGA

Upstream 100 bases:

>100_bases
CTTGCGCGCGCATCATGAGGATTCGCCGTCCCGAACGCGAGCTCGCCGCGCGGAATCGGCGCGTTGCGCGCACGGGACGG
TTCATTTGGAGATTTGACCT

Downstream 100 bases:

>100_bases
GCGCGTGTGCCTATCGCGGGGCGATTCGGCTCGTGCTGTTCGACGTCGACGGCGTGCTGACCGACGGCCGGCTGCAGGTG
ACGGGTGACGGCGAGTTCAT

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase 2; KDO-8-phosphate synthase 2; KDO 8-P synthase 2; KDOPS 2; Phospho-2-dehydro-3-deoxyoctonate aldolase 2 [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MNVAISPGITAGNDRPFVLFGGINVLESLDFTLEVCSEYAAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKILA
EVKARFGVPVITDVHEVEQAAPVAEVADVLQVPAFLARQTDLVVAIAKAAKPVNVKKPQFMSPTQVKHVVSKCLEAGNDR
VMLCERGSSFGYDNLVVDMLGFRQMAEATGGCPVIFDVTHSLQCRDPLGEASGGRRRQVLDLARAGVAVGIAGLFVEAHP
DPERARCDGPSALPLPLLEGFLSQMKAIDDLVKRMPALDIR

Sequences:

>Translated_281_residues
MNVAISPGITAGNDRPFVLFGGINVLESLDFTLEVCSEYAAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKILA
EVKARFGVPVITDVHEVEQAAPVAEVADVLQVPAFLARQTDLVVAIAKAAKPVNVKKPQFMSPTQVKHVVSKCLEAGNDR
VMLCERGSSFGYDNLVVDMLGFRQMAEATGGCPVIFDVTHSLQCRDPLGEASGGRRRQVLDLARAGVAVGIAGLFVEAHP
DPERARCDGPSALPLPLLEGFLSQMKAIDDLVKRMPALDIR
>Mature_281_residues
MNVAISPGITAGNDRPFVLFGGINVLESLDFTLEVCSEYAAVTRKLGIPFVFKASFDKANRSSIHSYRGVGLDEGLKILA
EVKARFGVPVITDVHEVEQAAPVAEVADVLQVPAFLARQTDLVVAIAKAAKPVNVKKPQFMSPTQVKHVVSKCLEAGNDR
VMLCERGSSFGYDNLVVDMLGFRQMAEATGGCPVIFDVTHSLQCRDPLGEASGGRRRQVLDLARAGVAVGIAGLFVEAHP
DPERARCDGPSALPLPLLEGFLSQMKAIDDLVKRMPALDIR

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=271, Percent_Identity=69.0036900369004, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 30195; Mature: 30195

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVAISPGITAGNDRPFVLFGGINVLESLDFTLEVCSEYAAVTRKLGIPFVFKASFDKAN
CCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
RSSIHSYRGVGLDEGLKILAEVKARFGVPVITDVHEVEQAAPVAEVADVLQVPAFLARQT
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DLVVAIAKAAKPVNVKKPQFMSPTQVKHVVSKCLEAGNDRVMLCERGSSFGYDNLVVDML
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHH
GFRQMAEATGGCPVIFDVTHSLQCRDPLGEASGGRRRQVLDLARAGVAVGIAGLFVEAHP
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCC
DPERARCDGPSALPLPLLEGFLSQMKAIDDLVKRMPALDIR
CCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNVAISPGITAGNDRPFVLFGGINVLESLDFTLEVCSEYAAVTRKLGIPFVFKASFDKAN
CCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
RSSIHSYRGVGLDEGLKILAEVKARFGVPVITDVHEVEQAAPVAEVADVLQVPAFLARQT
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DLVVAIAKAAKPVNVKKPQFMSPTQVKHVVSKCLEAGNDRVMLCERGSSFGYDNLVVDML
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHH
GFRQMAEATGGCPVIFDVTHSLQCRDPLGEASGGRRRQVLDLARAGVAVGIAGLFVEAHP
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCC
DPERARCDGPSALPLPLLEGFLSQMKAIDDLVKRMPALDIR
CCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA