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The map label for this gene is zraR [H]

Identifier: 83719176

GI number: 83719176

Start: 1887851

End: 1889236

Strand: Direct

Name: zraR [H]

Synonym: BTH_I1679

Alternate gene names: 83719176

Gene position: 1887851-1889236 (Clockwise)

Preceding gene: 83720595

Following gene: 83720929

Centisome position: 49.56

GC content: 67.6

Gene sequence:

>1386_bases
ATGGATGTTGCGGCAAGGCATCTCATCTACTATTCTCATCGTCCCGATGCGGATCTGCAGCGCTGTTTCGATCGGCATGG
CTGGCAGGTCGACATCGTCGATTCGCCACGCGAGATGCGGCGCTCCGCCGCGCGCGGCGTGATTGCGGGCGGCTTGCTCG
ATTTTTCGTGCGGTGTCGGGGCCGCCGAATTGCGCGAGCTCGAAGCGAGTCTGAAGACGCCGAACGTCGGCTGGATCGCG
ATGACGAGGCGAGGGCAGATGGGCGACGACGCGGTGCGCCGCCTCGTGCGCGATTACTGCTTCGACTACGTGACGGTGCC
TTACGAGTGCGAGCGCATCGTCGAGTCGGTCGGCCACGCATACGGGATGGTCACGTTGTCGGAAGGGCTCGCGCCCGCCG
CCGCGACGGTGCGCAACGAAGGCGAGATGGTCGGCACCTGCGACGCGATGCTCGCGCTCTTCAAGATGATCCGCAAGGTG
GCCGCGACCGACGCGCCCGTGTTCATCTCCGGCGAATCCGGCACCGGCAAGGAACTGACGGCCGTTGCGATTCACGAGCG
CTCGGCGCGCGCGAACGCGCCGTTCGTCGCGATCAATTGCGGCGCGATTCCGCCGACGCTGTTGCAGGCCGAGCTGTTCG
GCTACGAGCGCGGCGCGTTCACCGGCGCGAATCAGCGCAAGATCGGCCGTATCGAAGCGGCGAACGGCGGCACGCTGTTT
CTCGACGAAATCGGCGATCTGCCGTTCGAGAGCCAGGCGAGCCTGTTGCGCTTCCTGCAGGAACACAAGGTCGAGCGCGT
CGGCGGGCACCAGTCGATTTCGGTCGATGTGCGGATCGTTTCCGCGACGCATGTCGACATGCAGGTCGCGTTGCGCAACG
GGCGCTTTCGCGAGGACCTGTATCACCGGCTGTGCGTGCTGAAGCTCGAGGAGCCGCCGCTGCGCGAGCGCGGCAAGGAC
ATCGAGATCCTCGCGCGGCACATGCTCGAGCGCTTCAAGGGCGACGCGCACCGGCGGCTGCGCGGCTTCACGCCCGATGC
GATCGCGGCGCTTCACAACTATGCGTGGCCGGGCAACGTGCGCGAGCTGATCAACCGGGTGCGGCGCGCAATCGTGATGT
CGGAGGGGCGGATGATCAGCGCGGCCGATCTCGAACTGTCGGGGTACGCGGAAGTCGCGCCGATGTCGCTCGAGGAGGCG
CGCGAGAGCGCGGAGCGGCACGCGATCGAAGTCGCGCTGCTGCGGCATCGCGGCCGGCTCGCGGACGCCGCGCGCGAGCT
CGGCGTCTCGCGCGTGACGCTCTATCGCCTGCTTTGCGCATACGGGATGCGCGACGACGGCAGCACGCGCGCGAAGCGCG
ACGAGGATCTGCGCCGGGCCTGCTAG

Upstream 100 bases:

>100_bases
TGAAAAATGACGAGCCGAGTCCTCCTAGCGAGTCCCGGCTCGGTTCCGTCGCACGCCTGTGCCAGGCGGCGCGACGCAAA
TCGATTGACTGGGTGGCGTC

Downstream 100 bases:

>100_bases
CGCGGGCCTTGCTAGAATGGCGGGCACGGCCGCTTTTCGCGGCCGGAGGAACCCGCATGAAACAGTATCTCGATCTCGTT
CGCACCATTCTCGACACCGG

Product: sigma-54 dependent DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MDVAARHLIYYSHRPDADLQRCFDRHGWQVDIVDSPREMRRSAARGVIAGGLLDFSCGVGAAELRELEASLKTPNVGWIA
MTRRGQMGDDAVRRLVRDYCFDYVTVPYECERIVESVGHAYGMVTLSEGLAPAAATVRNEGEMVGTCDAMLALFKMIRKV
AATDAPVFISGESGTGKELTAVAIHERSARANAPFVAINCGAIPPTLLQAELFGYERGAFTGANQRKIGRIEAANGGTLF
LDEIGDLPFESQASLLRFLQEHKVERVGGHQSISVDVRIVSATHVDMQVALRNGRFREDLYHRLCVLKLEEPPLRERGKD
IEILARHMLERFKGDAHRRLRGFTPDAIAALHNYAWPGNVRELINRVRRAIVMSEGRMISAADLELSGYAEVAPMSLEEA
RESAERHAIEVALLRHRGRLADAARELGVSRVTLYRLLCAYGMRDDGSTRAKRDEDLRRAC

Sequences:

>Translated_461_residues
MDVAARHLIYYSHRPDADLQRCFDRHGWQVDIVDSPREMRRSAARGVIAGGLLDFSCGVGAAELRELEASLKTPNVGWIA
MTRRGQMGDDAVRRLVRDYCFDYVTVPYECERIVESVGHAYGMVTLSEGLAPAAATVRNEGEMVGTCDAMLALFKMIRKV
AATDAPVFISGESGTGKELTAVAIHERSARANAPFVAINCGAIPPTLLQAELFGYERGAFTGANQRKIGRIEAANGGTLF
LDEIGDLPFESQASLLRFLQEHKVERVGGHQSISVDVRIVSATHVDMQVALRNGRFREDLYHRLCVLKLEEPPLRERGKD
IEILARHMLERFKGDAHRRLRGFTPDAIAALHNYAWPGNVRELINRVRRAIVMSEGRMISAADLELSGYAEVAPMSLEEA
RESAERHAIEVALLRHRGRLADAARELGVSRVTLYRLLCAYGMRDDGSTRAKRDEDLRRAC
>Mature_461_residues
MDVAARHLIYYSHRPDADLQRCFDRHGWQVDIVDSPREMRRSAARGVIAGGLLDFSCGVGAAELRELEASLKTPNVGWIA
MTRRGQMGDDAVRRLVRDYCFDYVTVPYECERIVESVGHAYGMVTLSEGLAPAAATVRNEGEMVGTCDAMLALFKMIRKV
AATDAPVFISGESGTGKELTAVAIHERSARANAPFVAINCGAIPPTLLQAELFGYERGAFTGANQRKIGRIEAANGGTLF
LDEIGDLPFESQASLLRFLQEHKVERVGGHQSISVDVRIVSATHVDMQVALRNGRFREDLYHRLCVLKLEEPPLRERGKD
IEILARHMLERFKGDAHRRLRGFTPDAIAALHNYAWPGNVRELINRVRRAIVMSEGRMISAADLELSGYAEVAPMSLEEA
RESAERHAIEVALLRHRGRLADAARELGVSRVTLYRLLCAYGMRDDGSTRAKRDEDLRRAC

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=358, Percent_Identity=42.1787709497207, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1790437, Length=421, Percent_Identity=39.9049881235154, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1790299, Length=413, Percent_Identity=38.7409200968523, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1788905, Length=369, Percent_Identity=40.9214092140921, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=42.5, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI87082117, Length=280, Percent_Identity=43.2142857142857, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1789087, Length=300, Percent_Identity=41.3333333333333, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI87082152, Length=345, Percent_Identity=40.8695652173913, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1786524, Length=317, Percent_Identity=43.5331230283912, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=44.4444444444444, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787583, Length=319, Percent_Identity=36.9905956112853, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87081858, Length=293, Percent_Identity=31.740614334471, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1789828, Length=240, Percent_Identity=35.8333333333333, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51224; Mature: 51224

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVAARHLIYYSHRPDADLQRCFDRHGWQVDIVDSPREMRRSAARGVIAGGLLDFSCGVG
CCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHCCHHCCCCEECCCCCC
AAELRELEASLKTPNVGWIAMTRRGQMGDDAVRRLVRDYCFDYVTVPYECERIVESVGHA
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHH
YGMVTLSEGLAPAAATVRNEGEMVGTCDAMLALFKMIRKVAATDAPVFISGESGTGKELT
HEEEECCCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEE
AVAIHERSARANAPFVAINCGAIPPTLLQAELFGYERGAFTGANQRKIGRIEAANGGTLF
EEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEE
LDEIGDLPFESQASLLRFLQEHKVERVGGHQSISVDVRIVSATHVDMQVALRNGRFREDL
EEHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEEHHHCCCHHHHH
YHRLCVLKLEEPPLRERGKDIEILARHMLERFKGDAHRRLRGFTPDAIAALHNYAWPGNV
HHHHEEEECCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCCCCHH
RELINRVRRAIVMSEGRMISAADLELSGYAEVAPMSLEEARESAERHAIEVALLRHRGRL
HHHHHHHHHHHHHCCCCEEEEECCEECCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCHH
ADAARELGVSRVTLYRLLCAYGMRDDGSTRAKRDEDLRRAC
HHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MDVAARHLIYYSHRPDADLQRCFDRHGWQVDIVDSPREMRRSAARGVIAGGLLDFSCGVG
CCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHCCHHCCCCEECCCCCC
AAELRELEASLKTPNVGWIAMTRRGQMGDDAVRRLVRDYCFDYVTVPYECERIVESVGHA
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHH
YGMVTLSEGLAPAAATVRNEGEMVGTCDAMLALFKMIRKVAATDAPVFISGESGTGKELT
HEEEECCCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEE
AVAIHERSARANAPFVAINCGAIPPTLLQAELFGYERGAFTGANQRKIGRIEAANGGTLF
EEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEE
LDEIGDLPFESQASLLRFLQEHKVERVGGHQSISVDVRIVSATHVDMQVALRNGRFREDL
EEHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEEHHHCCCHHHHH
YHRLCVLKLEEPPLRERGKDIEILARHMLERFKGDAHRRLRGFTPDAIAALHNYAWPGNV
HHHHEEEECCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCCCCHH
RELINRVRRAIVMSEGRMISAADLELSGYAEVAPMSLEEARESAERHAIEVALLRHRGRL
HHHHHHHHHHHHHCCCCEEEEECCEECCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCHH
ADAARELGVSRVTLYRLLCAYGMRDDGSTRAKRDEDLRRAC
HHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]