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The map label for this gene is nuoN [H]

Identifier: 83718846

GI number: 83718846

Start: 1217064

End: 1218521

Strand: Direct

Name: nuoN [H]

Synonym: BTH_I1074

Alternate gene names: 83718846

Gene position: 1217064-1218521 (Clockwise)

Preceding gene: 83719938

Following gene: 83720714

Centisome position: 31.95

GC content: 64.81

Gene sequence:

>1458_bases
ATGAATGTCCTGTTGCCTGATGCGCTGGTGATGGCCGCCATCATCGTCGCCTGGCTGAACGACACCTTCGTCGGCGCAGC
CGGCCGCCGCCTCACGTATCTGATCGCGGTCGTCGCGTCGGCGGCGGCGGGCGTGTGGTTCGCACTGCAAGCCTTCGATC
CGCAGCAGTATTACTTCTTCTCGCGGATGGTCGTGGTCGATTCGTTCGCGAGCGCGATGAAGGCGGTCGTGTCGATCGGC
TTCGCGGTGACACTCGTCTACTCGCGCAAGTACCTCGAGGATCGCGACCTGTTCCGCGGCGACGTGTTCCTGCTCGGCAT
GTTCTCGCTGCTCGGCCAGCTCGTGATGATCTCGGGCAACAACTTCCTCACGCTGTACCTCGGCCTCGAGCTGATGTCGC
TGTCGCTGTACGCGGTGATCGCGCTGCGTCGCGACGGCGCGCAGTCGAGCGAAGCGGCGATGAAGTACTACGTGCTCGGC
GCGCTCGCTTCGGGCTTCGTGCTTTACGGGATTTCGATGCTGTACGGCGCGACGGGCTCGCTCGAGCTGAACGAAGTGCT
GAAGGCGGTCGCATCGGGCCGCATCAACGACGCGGTGCTGCTGTTCGGCGTGATCTTCATCGTCGCGGGCGTCGCGTTCA
AGCTCGGCGCCGTGCCGTTCCACATGTGGGTGCCGGACGTCTACCAGGGCGCACCCACCGCGATGACGCTCTTCGTCGGC
GGCGGCCCGAAGGTCGCGGCGTTCGCGTGGGGCCTGCGCTTCCTCGTGATGGGCCTGCTGCCGCTCGCGGTCGACTGGCA
GGAAATGCTCGTGATCCTCGCCGCGCTGTCGCTGATCGTCGGCAACATTACCGGTATCGTCCAGCGCAACATCAAGCGGA
TGCTCGCGTACTCGGCGATCTCGAACATGGGCTTCGTGCTGCTCGGTCTGCTCGCGGGCGTCGTCAACGGCAATCCGTCG
TCGGCGGCGAGCGCTTACAGCTCGGCGATGTTCTACACGATCGTCTACCTCGTGACCACGCTCGGCTCGTTCGGTGTCGT
GATGCTGCTTGCGCGCCGCGATTTCGAAGCGGAAACGCTCGACGACTTCAAGGGCCTCAACAAGCGCAGCCCGGTGTTCG
CGTTCGTGATGATGGTGATGATGTTCTCGCTTGCCGGCATTCCGCCGACGGTCGGCTTCTACGCGAAGCTCGCCGTTCTG
GAGGCGACGGTCAACGCCGGCCTCACGTGGCTCGCGGTGCTCGCCGTCATCACGTCGCTGTTCGGCGCGTTCTACTATCT
GCGCATCGTCAAGCTGATGTACTTCGACGCGCCGCAGGACACGACGCCGATCGCGGGCGACGCATGCAAGCGCGCGATCC
TCGTGCTCAACGGCCTCGCAGTCGTCGTGCTCGGCATCGTGCCGGGCCCGCTGATGACGATCTGCCTGCAGGCCATCAGC
CACACGCTGCCGCTGTAA

Upstream 100 bases:

>100_bases
CGTTTCCGTGGAAAACCTCCTCTCCCACGTCGCGCAGTCGAAACTGCCGCTGGCCCAGTAAGCCCGAGCGGAGGATACAA
AGATCATGCAAAACGCACCT

Downstream 100 bases:

>100_bases
TGTCGGCCGCCGGCTGGTTCATCGTGCTGTTGGCGCTCGTGGGCGCCAACCTGCCGTTCCTGAATCAGCGCCTGTTCGCC
GTCGTGCCGCTGAAAAGCGG

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNVLLPDALVMAAIIVAWLNDTFVGAAGRRLTYLIAVVASAAAGVWFALQAFDPQQYYFFSRMVVVDSFASAMKAVVSIG
FAVTLVYSRKYLEDRDLFRGDVFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYAVIALRRDGAQSSEAAMKYYVLG
ALASGFVLYGISMLYGATGSLELNEVLKAVASGRINDAVLLFGVIFIVAGVAFKLGAVPFHMWVPDVYQGAPTAMTLFVG
GGPKVAAFAWGLRFLVMGLLPLAVDWQEMLVILAALSLIVGNITGIVQRNIKRMLAYSAISNMGFVLLGLLAGVVNGNPS
SAASAYSSAMFYTIVYLVTTLGSFGVVMLLARRDFEAETLDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKLAVL
EATVNAGLTWLAVLAVITSLFGAFYYLRIVKLMYFDAPQDTTPIAGDACKRAILVLNGLAVVVLGIVPGPLMTICLQAIS
HTLPL

Sequences:

>Translated_485_residues
MNVLLPDALVMAAIIVAWLNDTFVGAAGRRLTYLIAVVASAAAGVWFALQAFDPQQYYFFSRMVVVDSFASAMKAVVSIG
FAVTLVYSRKYLEDRDLFRGDVFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYAVIALRRDGAQSSEAAMKYYVLG
ALASGFVLYGISMLYGATGSLELNEVLKAVASGRINDAVLLFGVIFIVAGVAFKLGAVPFHMWVPDVYQGAPTAMTLFVG
GGPKVAAFAWGLRFLVMGLLPLAVDWQEMLVILAALSLIVGNITGIVQRNIKRMLAYSAISNMGFVLLGLLAGVVNGNPS
SAASAYSSAMFYTIVYLVTTLGSFGVVMLLARRDFEAETLDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKLAVL
EATVNAGLTWLAVLAVITSLFGAFYYLRIVKLMYFDAPQDTTPIAGDACKRAILVLNGLAVVVLGIVPGPLMTICLQAIS
HTLPL
>Mature_485_residues
MNVLLPDALVMAAIIVAWLNDTFVGAAGRRLTYLIAVVASAAAGVWFALQAFDPQQYYFFSRMVVVDSFASAMKAVVSIG
FAVTLVYSRKYLEDRDLFRGDVFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYAVIALRRDGAQSSEAAMKYYVLG
ALASGFVLYGISMLYGATGSLELNEVLKAVASGRINDAVLLFGVIFIVAGVAFKLGAVPFHMWVPDVYQGAPTAMTLFVG
GGPKVAAFAWGLRFLVMGLLPLAVDWQEMLVILAALSLIVGNITGIVQRNIKRMLAYSAISNMGFVLLGLLAGVVNGNPS
SAASAYSSAMFYTIVYLVTTLGSFGVVMLLARRDFEAETLDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKLAVL
EATVNAGLTWLAVLAVITSLFGAFYYLRIVKLMYFDAPQDTTPIAGDACKRAILVLNGLAVVVLGIVPGPLMTICLQAIS
HTLPL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=331, Percent_Identity=25.0755287009063, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI145693160, Length=466, Percent_Identity=33.2618025751073, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1788614, Length=419, Percent_Identity=23.1503579952267, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788831, Length=386, Percent_Identity=25.9067357512953, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788827, Length=328, Percent_Identity=25.9146341463415, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788613, Length=376, Percent_Identity=26.063829787234, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI2367154, Length=263, Percent_Identity=25.8555133079848, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52041; Mature: 52041

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCC
>Mature Secondary Structure
MNVLLPDALVMAAIIVAWLNDTFVGAAGRRLTYLIAVVASAAAGVWFALQAFDPQQYYFF
CCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHH
SRMVVVDSFASAMKAVVSIGFAVTLVYSRKYLEDRDLFRGDVFLLGMFSLLGQLVMISGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
NFLTLYLGLELMSLSLYAVIALRRDGAQSSEAAMKYYVLGALASGFVLYGISMLYGATGS
CEEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LELNEVLKAVASGRINDAVLLFGVIFIVAGVAFKLGAVPFHMWVPDVYQGAPTAMTLFVG
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCEEEEEEC
GGPKVAAFAWGLRFLVMGLLPLAVDWQEMLVILAALSLIVGNITGIVQRNIKRMLAYSAI
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNMGFVLLGLLAGVVNGNPSSAASAYSSAMFYTIVYLVTTLGSFGVVMLLARRDFEAETL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKLAVLEATVNAGLTWLAVLAVITSL
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FGAFYYLRIVKLMYFDAPQDTTPIAGDACKRAILVLNGLAVVVLGIVPGPLMTICLQAIS
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HTLPL
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA