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The map label for this gene is rcsC [C]

Identifier: 83593808

GI number: 83593808

Start: 2871629

End: 2873281

Strand: Direct

Name: rcsC [C]

Synonym: Rru_A2473

Alternate gene names: 83593808

Gene position: 2871629-2873281 (Clockwise)

Preceding gene: 83593806

Following gene: 83593809

Centisome position: 65.97

GC content: 63.7

Gene sequence:

>1653_bases
GTGACAAACAGCCGCGTAAAGGCAGACCAGGATGGCGCCGTCAAGCCGGTCGCCGGTGGTGAGTCCCTCCCCCAAAGCGA
CGGCTCGGCCGATCGCCTTACCGGCCTCAGCCTGCATTCCCTTGTCATCGAGCATATGGACCAGGGCGTGCTGGTCGCCG
ACGCCAAAACCCGCGTCATCGCCTGGAACCGCCGGGCCTGCGAGCTTTTGGGGGTCTCGGCCGACTTCCTCGCCAGCGGG
CCAACCCATGTCGAGGTTCTGGGCGAGATGATCCGCACCGGCGCCCTGGTCACCGCCGAGATCGATCCCGTCAGCACCCT
CATCGCCGCGTGGCTTGATCTTCCCGAAGGCGAACGCCGCCCCTTGATCTATGAACGCGGCAATCCGACCGGCCTGCGCA
TCGAGGTCCGCACCTCGCCGTTGCCCGAGGGGGGCTATGTAAGAACCTTCACCGACATCACCCAACGCAAGGCCGCCGAA
CAGGCCCTGGCCGAAAAGACCCGGCTTCTCGACACCACCTTGGAAACCATCGCCCAGGGAATCATCCTGGTCGATCCCTC
CCTGCACATCGTGCTGTGCAACCGCCGCTACCGCGAGCTTCTTGATCTGCCCGATTATATGCTCGAGCCCTTTCCGCCGC
GGGCGGCCGATATCATCGCCTTCCAGATCGGACGGGGCGATTTCGACATCCTGCCCGCCGACGTTACCCATCGGCCGTTC
TGGGATCGGATCGAAGGCTTCGTTTTTTCGCCCGGAACCACCGAACGACCGTTACGGGACGGGCGGACGCTGGGCGTGGA
GACCTTCGCCCTTGATGGCGGCGGCTGGGTCCGCACCTTTACCGATATCACCGAAGGCAAACGGGCCCAGGACGCCTTGC
TGGTTTCCGAAAAGATGGCCTCGCTTGGCCAGTTGGTCGCCGGCATCGCCCATGAGATCAACACGCCGATCGGCACCGGC
GTCACCGCGGCCTCGCTGCTCGCCGAAAAGACCCAATCCCTGGTCCAGGCCGTGGAGGCCGGAGCCTTGCGGCGCTCGCA
GCTTGACGCTTATCTCCACGTCGCCCGGGAATCCTCGCGGTTCATCCTATCGAACCTGACCCGCGCCGCCGAATTGATCC
AAAGCTTCAAGCAGGTGGCCGTCGATCAGGCGACCGATGAAAGCCGGTTGTTCAAGGTGCGCGACTACCTGGAAGAAATC
CTGCTCAGCCTCCAGCCACGCCTTAAGCGCACCCCCCACACGATGACCCTTGAATGCCCGGACGATCTGGCGATGTATGG
CCCGCCGGGGGCGCTTTTCCGGGTCATCACCAATCTGGTGATCAACTCGCTGATGCATGGCCTTGAGGAGGGCGCGACGG
CGCCGCCGGGGCACATGGTCTTGCGGGTTGGGCACGAAAAAGACACCGATTGCGTGGTTTTTCGCTACCATGATACCGGC
AGGGGCATTCCCGAGAAAAATCTCAAGCGGATTTTCGACCCGTTCTTCACCACGCGACGCGGCGAAGGGGGAACCGGCCT
GGGCCTGCACATCGTCTATAATCTGGTCACGCAAACCCTGGGGGGAAGCTTGGCCGTGCACAGCCCCCCCGGTCAGGGCG
CGATCTTTTTGATAAGGGTCCCGCGCCTTTCGGCCGGCCTTCCCGAGGGATGA

Upstream 100 bases:

>100_bases
CGTCGTGCCGCAACCCTGACTTTTCGTCATATGTATTGAGTCCCGGGCCGCGCGAGCCTACTTTAAATTCTGGCTATTTC
CTGCCCCCCATGAGGCGACG

Downstream 100 bases:

>100_bases
CGGTGGCCCGGGCGGCAAGGCGCCAAAGGATGGCGCTGCTGATGACGGCCTGGATAGTCCTGACGGCCCCCGCCGCTTCG
ACCGCCGCCGAGTTCCGCTG

Product: PAS/PAC sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTNSRVKADQDGAVKPVAGGESLPQSDGSADRLTGLSLHSLVIEHMDQGVLVADAKTRVIAWNRRACELLGVSADFLASG
PTHVEVLGEMIRTGALVTAEIDPVSTLIAAWLDLPEGERRPLIYERGNPTGLRIEVRTSPLPEGGYVRTFTDITQRKAAE
QALAEKTRLLDTTLETIAQGIILVDPSLHIVLCNRRYRELLDLPDYMLEPFPPRAADIIAFQIGRGDFDILPADVTHRPF
WDRIEGFVFSPGTTERPLRDGRTLGVETFALDGGGWVRTFTDITEGKRAQDALLVSEKMASLGQLVAGIAHEINTPIGTG
VTAASLLAEKTQSLVQAVEAGALRRSQLDAYLHVARESSRFILSNLTRAAELIQSFKQVAVDQATDESRLFKVRDYLEEI
LLSLQPRLKRTPHTMTLECPDDLAMYGPPGALFRVITNLVINSLMHGLEEGATAPPGHMVLRVGHEKDTDCVVFRYHDTG
RGIPEKNLKRIFDPFFTTRRGEGGTGLGLHIVYNLVTQTLGGSLAVHSPPGQGAIFLIRVPRLSAGLPEG

Sequences:

>Translated_550_residues
MTNSRVKADQDGAVKPVAGGESLPQSDGSADRLTGLSLHSLVIEHMDQGVLVADAKTRVIAWNRRACELLGVSADFLASG
PTHVEVLGEMIRTGALVTAEIDPVSTLIAAWLDLPEGERRPLIYERGNPTGLRIEVRTSPLPEGGYVRTFTDITQRKAAE
QALAEKTRLLDTTLETIAQGIILVDPSLHIVLCNRRYRELLDLPDYMLEPFPPRAADIIAFQIGRGDFDILPADVTHRPF
WDRIEGFVFSPGTTERPLRDGRTLGVETFALDGGGWVRTFTDITEGKRAQDALLVSEKMASLGQLVAGIAHEINTPIGTG
VTAASLLAEKTQSLVQAVEAGALRRSQLDAYLHVARESSRFILSNLTRAAELIQSFKQVAVDQATDESRLFKVRDYLEEI
LLSLQPRLKRTPHTMTLECPDDLAMYGPPGALFRVITNLVINSLMHGLEEGATAPPGHMVLRVGHEKDTDCVVFRYHDTG
RGIPEKNLKRIFDPFFTTRRGEGGTGLGLHIVYNLVTQTLGGSLAVHSPPGQGAIFLIRVPRLSAGLPEG
>Mature_549_residues
TNSRVKADQDGAVKPVAGGESLPQSDGSADRLTGLSLHSLVIEHMDQGVLVADAKTRVIAWNRRACELLGVSADFLASGP
THVEVLGEMIRTGALVTAEIDPVSTLIAAWLDLPEGERRPLIYERGNPTGLRIEVRTSPLPEGGYVRTFTDITQRKAAEQ
ALAEKTRLLDTTLETIAQGIILVDPSLHIVLCNRRYRELLDLPDYMLEPFPPRAADIIAFQIGRGDFDILPADVTHRPFW
DRIEGFVFSPGTTERPLRDGRTLGVETFALDGGGWVRTFTDITEGKRAQDALLVSEKMASLGQLVAGIAHEINTPIGTGV
TAASLLAEKTQSLVQAVEAGALRRSQLDAYLHVARESSRFILSNLTRAAELIQSFKQVAVDQATDESRLFKVRDYLEEIL
LSLQPRLKRTPHTMTLECPDDLAMYGPPGALFRVITNLVINSLMHGLEEGATAPPGHMVLRVGHEKDTDCVVFRYHDTGR
GIPEKNLKRIFDPFFTTRRGEGGTGLGLHIVYNLVTQTLGGSLAVHSPPGQGAIFLIRVPRLSAGLPEG

Specific function: Member Of The Two-Component Regulatory System rcsC/rcsB Involved In The Regulation Of The Expression Of Genes Involved In Colanic Acid Capsule Synthesis. rcsC Probably Functions As A Membrane-Associated Protein Kinase That Phosphorylates rcsB In Response

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=30.3501945525292, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790436, Length=273, Percent_Identity=27.4725274725275, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081816, Length=246, Percent_Identity=32.1138211382114, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1789149, Length=263, Percent_Identity=27.3764258555133, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=25.4032258064516, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60028; Mature: 59896

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSRVKADQDGAVKPVAGGESLPQSDGSADRLTGLSLHSLVIEHMDQGVLVADAKTRVI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEEECCCEEEE
AWNRRACELLGVSADFLASGPTHVEVLGEMIRTGALVTAEIDPVSTLIAAWLDLPEGERR
EECCCHHHHCCCCHHHHCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCCCC
PLIYERGNPTGLRIEVRTSPLPEGGYVRTFTDITQRKAAEQALAEKTRLLDTTLETIAQG
CEEEECCCCCEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IILVDPSLHIVLCNRRYRELLDLPDYMLEPFPPRAADIIAFQIGRGDFDILPADVTHRPF
EEEECCCEEEEECCHHHHHHHCCCHHHHCCCCCCCCEEEEEEECCCCCEEECCCCCCCCC
WDRIEGFVFSPGTTERPLRDGRTLGVETFALDGGGWVRTFTDITEGKRAQDALLVSEKMA
HHHHCCEEECCCCCCCCCCCCCEECEEEEEECCCCEEEEHHHHHCCCHHHHHHHHHHHHH
SLGQLVAGIAHEINTPIGTGVTAASLLAEKTQSLVQAVEAGALRRSQLDAYLHVARESSR
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
FILSNLTRAAELIQSFKQVAVDQATDESRLFKVRDYLEEILLSLQPRLKRTPHTMTLECP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECC
DDLAMYGPPGALFRVITNLVINSLMHGLEEGATAPPGHMVLRVGHEKDTDCVVFRYHDTG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEECCC
RGIPEKNLKRIFDPFFTTRRGEGGTGLGLHIVYNLVTQTLGGSLAVHSPPGQGAIFLIRV
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEC
PRLSAGLPEG
CCCCCCCCCC
>Mature Secondary Structure 
TNSRVKADQDGAVKPVAGGESLPQSDGSADRLTGLSLHSLVIEHMDQGVLVADAKTRVI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEEECCCEEEE
AWNRRACELLGVSADFLASGPTHVEVLGEMIRTGALVTAEIDPVSTLIAAWLDLPEGERR
EECCCHHHHCCCCHHHHCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCCCC
PLIYERGNPTGLRIEVRTSPLPEGGYVRTFTDITQRKAAEQALAEKTRLLDTTLETIAQG
CEEEECCCCCEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IILVDPSLHIVLCNRRYRELLDLPDYMLEPFPPRAADIIAFQIGRGDFDILPADVTHRPF
EEEECCCEEEEECCHHHHHHHCCCHHHHCCCCCCCCEEEEEEECCCCCEEECCCCCCCCC
WDRIEGFVFSPGTTERPLRDGRTLGVETFALDGGGWVRTFTDITEGKRAQDALLVSEKMA
HHHHCCEEECCCCCCCCCCCCCEECEEEEEECCCCEEEEHHHHHCCCHHHHHHHHHHHHH
SLGQLVAGIAHEINTPIGTGVTAASLLAEKTQSLVQAVEAGALRRSQLDAYLHVARESSR
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
FILSNLTRAAELIQSFKQVAVDQATDESRLFKVRDYLEEILLSLQPRLKRTPHTMTLECP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECC
DDLAMYGPPGALFRVITNLVINSLMHGLEEGATAPPGHMVLRVGHEKDTDCVVFRYHDTG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEECCC
RGIPEKNLKRIFDPFFTTRRGEGGTGLGLHIVYNLVTQTLGGSLAVHSPPGQGAIFLIRV
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEC
PRLSAGLPEG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1333793 [H]