Click here to switch to the map view.

The map label for this gene is fbp [H]

Identifier: 83593738

GI number: 83593738

Start: 2797825

End: 2798934

Strand: Direct

Name: fbp [H]

Synonym: Rru_A2403

Alternate gene names: 83593738

Gene position: 2797825-2798934 (Clockwise)

Preceding gene: 83593737

Following gene: 83593739

Centisome position: 64.28

GC content: 64.86

Gene sequence:

>1110_bases
ATGTCCGTTCTGTCACAGGACCGTCCGCGCGAAAGGCCTCCCATGCTCGCCACCGATCGCACCACGCTTGCGCAGTTCCT
TGTCGAGGAATGCCGGGGCCGCGCCGGCGATGATTCCGAGCTTCTTGGTTTGTTGCTCGACGTCGCCCAGGCCTGCAAGA
CCATCTCGAAGATGACGGCGATGGGCTCGCTCGCCGGGGTTCATGGCTATAACGGCGATGTCAATCCCCAGGGCGAGAAT
CAGGCGCGGCTCGACCTGATGTCCAATCAGGCCTTCGTCCGCGCCACCGAACGCACCGGCCATGCCGCCGGTCTGGCCAG
CGAGGAGATGGAAGAGGTTCTGGGCTTCCCCGAGTCCTACGCCCGGGGCACCTTGCTGCTGGTCTTCGATCCCCTCGACG
GATCGTCCAACATCGATATCAACGGCACCGTCGGCTCGATCTTTTCGATCCTGCCGATGCCCCGCCCCGGCGAAGCCCCG
CAGACCGCCGACTTCCTGCAATCGGGCCGCCAGCAGGTGGCCGCCGGCTATGCCCTTTATGGCCCCTCGACCATGTTCGT
GCTGACCATCGGCTCGGGCGTTCACGGCTTCACCCTCGATCCGCTGCTTGGCGATTTCATTCTGACCCACCCGTCGATGA
CGGTGATCCCCGAAAGCGGCGAATTCGCCATCAACAGCTCGAACAGCCGCTTCTGGGAACCGCCGATCCGCGCCTATGTC
GATGAATTGCTGGCCGGGCGCTCGGGTCCGCGGTCCAAGGATTACAACATGCGCTGGATCGCCGCCCTGGTGGCCGATGT
CCACCGCATCTTGCTGCGCGGCGGCATCTATCTGTATCCCCGCGACACCAAGACCCCCGATCTGGCCGGGCGCCTGCGCC
TGCTCTATGAAGCCGCCCCGGTGGCCTTTTTGATGGAACAGGCTGGCGGCCGCTGCACCACCGGCACGCGGACCATGCTC
GACCTCGTGCCCGGGTCCTTGCACGAACGCGTACCGCTGATCTTCGGGTCGGCCGTGGAAGTGGAGCGGGTCGAGACCCT
TTACCGCGAGCCGCAACGCCGGGAATTCGCCACGCCGTTGTTCAATCAGCGCGGCTTGTTCCGCGACTAA

Upstream 100 bases:

>100_bases
GGTGGCCGGTTCGGCCATCTTCGGAGCGAGTGACCGGGCCAAGGCCATCGCCTCCATCCGGGGCGCCGCGGAAAGTGGAT
TAGGTCAGGAAGCCGCATAA

Downstream 100 bases:

>100_bases
AGCGGCGTACCGCCGACCGGGGACGTCGGCGCTTACACCATCGTCACCAAAAAAGCGGCAGAGCGGTCAGATCACCACCG
CTCGACAGGGGGAAGCACGA

Product: D-fructose 1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSVLSQDRPRERPPMLATDRTTLAQFLVEECRGRAGDDSELLGLLLDVAQACKTISKMTAMGSLAGVHGYNGDVNPQGEN
QARLDLMSNQAFVRATERTGHAAGLASEEMEEVLGFPESYARGTLLLVFDPLDGSSNIDINGTVGSIFSILPMPRPGEAP
QTADFLQSGRQQVAAGYALYGPSTMFVLTIGSGVHGFTLDPLLGDFILTHPSMTVIPESGEFAINSSNSRFWEPPIRAYV
DELLAGRSGPRSKDYNMRWIAALVADVHRILLRGGIYLYPRDTKTPDLAGRLRLLYEAAPVAFLMEQAGGRCTTGTRTML
DLVPGSLHERVPLIFGSAVEVERVETLYREPQRREFATPLFNQRGLFRD

Sequences:

>Translated_369_residues
MSVLSQDRPRERPPMLATDRTTLAQFLVEECRGRAGDDSELLGLLLDVAQACKTISKMTAMGSLAGVHGYNGDVNPQGEN
QARLDLMSNQAFVRATERTGHAAGLASEEMEEVLGFPESYARGTLLLVFDPLDGSSNIDINGTVGSIFSILPMPRPGEAP
QTADFLQSGRQQVAAGYALYGPSTMFVLTIGSGVHGFTLDPLLGDFILTHPSMTVIPESGEFAINSSNSRFWEPPIRAYV
DELLAGRSGPRSKDYNMRWIAALVADVHRILLRGGIYLYPRDTKTPDLAGRLRLLYEAAPVAFLMEQAGGRCTTGTRTML
DLVPGSLHERVPLIFGSAVEVERVETLYREPQRREFATPLFNQRGLFRD
>Mature_368_residues
SVLSQDRPRERPPMLATDRTTLAQFLVEECRGRAGDDSELLGLLLDVAQACKTISKMTAMGSLAGVHGYNGDVNPQGENQ
ARLDLMSNQAFVRATERTGHAAGLASEEMEEVLGFPESYARGTLLLVFDPLDGSSNIDINGTVGSIFSILPMPRPGEAPQ
TADFLQSGRQQVAAGYALYGPSTMFVLTIGSGVHGFTLDPLLGDFILTHPSMTVIPESGEFAINSSNSRFWEPPIRAYVD
ELLAGRSGPRSKDYNMRWIAALVADVHRILLRGGIYLYPRDTKTPDLAGRLRLLYEAAPVAFLMEQAGGRCTTGTRTMLD
LVPGSLHERVPLIFGSAVEVERVETLYREPQRREFATPLFNQRGLFRD

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=342, Percent_Identity=38.8888888888889, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI189083692, Length=335, Percent_Identity=38.5074626865672, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI16579888, Length=335, Percent_Identity=38.5074626865672, Blast_Score=226, Evalue=3e-59,
Organism=Escherichia coli, GI1790679, Length=331, Percent_Identity=42.5981873111783, Blast_Score=241, Evalue=5e-65,
Organism=Caenorhabditis elegans, GI17508131, Length=329, Percent_Identity=40.4255319148936, Blast_Score=253, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6323409, Length=340, Percent_Identity=38.5294117647059, Blast_Score=236, Evalue=4e-63,
Organism=Drosophila melanogaster, GI45550998, Length=335, Percent_Identity=40.5970149253731, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI19921562, Length=335, Percent_Identity=40.5970149253731, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR020548 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 40408; Mature: 40276

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLSQDRPRERPPMLATDRTTLAQFLVEECRGRAGDDSELLGLLLDVAQACKTISKMTA
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MGSLAGVHGYNGDVNPQGENQARLDLMSNQAFVRATERTGHAAGLASEEMEEVLGFPESY
HHHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHCCCHHH
ARGTLLLVFDPLDGSSNIDINGTVGSIFSILPMPRPGEAPQTADFLQSGRQQVAAGYALY
CCCEEEEEEECCCCCCCEEECCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEE
GPSTMFVLTIGSGVHGFTLDPLLGDFILTHPSMTVIPESGEFAINSSNSRFWEPPIRAYV
CCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCCHHHHHH
DELLAGRSGPRSKDYNMRWIAALVADVHRILLRGGIYLYPRDTKTPDLAGRLRLLYEAAP
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHH
VAFLMEQAGGRCTTGTRTMLDLVPGSLHERVPLIFGSAVEVERVETLYREPQRREFATPL
HHHHHHHCCCCCCCCCHHHHHHCCCCHHHCCCEEECCCHHHHHHHHHHHCHHHHHHHCCH
FNQRGLFRD
HCCCCCCCC
>Mature Secondary Structure 
SVLSQDRPRERPPMLATDRTTLAQFLVEECRGRAGDDSELLGLLLDVAQACKTISKMTA
CCCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MGSLAGVHGYNGDVNPQGENQARLDLMSNQAFVRATERTGHAAGLASEEMEEVLGFPESY
HHHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHCCCHHH
ARGTLLLVFDPLDGSSNIDINGTVGSIFSILPMPRPGEAPQTADFLQSGRQQVAAGYALY
CCCEEEEEEECCCCCCCEEECCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEE
GPSTMFVLTIGSGVHGFTLDPLLGDFILTHPSMTVIPESGEFAINSSNSRFWEPPIRAYV
CCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCCHHHHHH
DELLAGRSGPRSKDYNMRWIAALVADVHRILLRGGIYLYPRDTKTPDLAGRLRLLYEAAP
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHH
VAFLMEQAGGRCTTGTRTMLDLVPGSLHERVPLIFGSAVEVERVETLYREPQRREFATPL
HHHHHHHCCCCCCCCCHHHHHHCCCCHHHCCCEEECCCHHHHHHHHHHHCHHHHHHHCCH
FNQRGLFRD
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA