Click here to switch to the map view.

The map label for this gene is dppA [H]

Identifier: 83593691

GI number: 83593691

Start: 2742295

End: 2743884

Strand: Direct

Name: dppA [H]

Synonym: Rru_A2356

Alternate gene names: 83593691

Gene position: 2742295-2743884 (Clockwise)

Preceding gene: 83593689

Following gene: 83593692

Centisome position: 63.0

GC content: 60.31

Gene sequence:

>1590_bases
ATGCGCAAAATAGTGATTGGCGCGGCTTCGGCCGTTATCCTCGCCATGGCGGCGAGCGGGGCCCAGGCCAAGACGCTGGT
CTATTGCTCGGAAGGCAGCCCCGAGGGCTTCAATCCGGCTTTTTACACCACCGGCACGACCTTCGACGCCACCAGCAAGA
ACATTTTCGACAAGCTCGTTCTTTTCAAGCGCGGCACCACGGAGATCGAACCCGGTCTGGCCGAGAGCTGGGAGGTTTCG
CCCGACGGCAAGACCTATACCTTCCACCTGCGCAAGGGCGTGACCTTCCACGACAGCGACATCTTCAAGCCGACGCGGCA
ATTCAACGCCGATGACGTGATCTGGAGCTTCGAGCGTCAGTTGAAGAAGGATCACCCCTATCACGCGGTTTCCGGCGGCA
CCTACGACTACTTCGAAGGCATGTCGATGAACACCCTTCTCGAAAAGATCGAGAAGGTCGACGATTATACGGTGGTCTTC
CACCTGAGCCGCCCCGAAGCGCCGATGCTGGCCAATCTGGCCATGGACTTCGCCTCGATCTTCTCGGCCGAATACGCCGA
TAAGATGATGAAGGCCGGAACCCCGGAAGTCGTTGACCAGAAGCCGATCGGCACCGGTCCCTTCATGTTCCGCGGTTACC
AGAAGGACGCCCAGATCCGCTACGAGGCCAATCCGACCTATTGGCAGGGCAAGGCCGCCATCGACCGCCTGGTTTTCGTC
ATCACCCCCGACGCCAGCGTGCGCTACGCCAAGCTGAAGGCCGGCGAATGCCATGTGATGCCCTATCCCAATCCGGCCGA
CCTGGAAGCCATGAAGACCGACAAGGCGGTCAACCTGATGCACCAGGAAGGCCTGAACGTCGGCTATCTGGCCTATAACG
TCGAGAAGAAGCCCTTCGACGACGTGCGCGTGCGCAAGGCCCTCAATCTGGCGATCGACAAGAAGGCGATCATCGACGCC
GTTTATCAGGGCGCCGGCACCGCCGCCACCAACCCGATCCCGCCGACGATCTGGTCCTACAACAAGGCCGTCAAGGACGA
CGCCTTCGATCCGGCCGCCGCCAAGAAGCTGCTGGCCGAAGCCGGGGTGAAGGATCTCAAGACCACCATCTGGGCAATGC
CCGTCCAGCGCCCCTACAACCCCAATGCCCGCCGCATGGCCGAAATCCTTCAGGCCAACTGGAAGGCCGTGGGCGTGGAT
GCCGAAATCACCTCCTACGAATGGGGCGAATACCTCAAGCGCGCCAAGGCCGGCGAGCATGAGACGGCGCTGTTTGGCTG
GACCGGCGACAATGGCGATCCCGATAATTTCCTGGCGGTTCTGCTGGGCTGCGACGCCATCCCCGGCAACAACTATGCGC
GCTGGTGCGACAAGTCCTTTGAAAACCTGATCCAGAAGGCCAAGATCGCCACCAGCCAGGAAGAGCGGGTGAAGCTCTAC
GAAGAGGCTCAGGTCATCTTCAAGGAGCAGGCCCCCTGGGCGACGATCGCGCATTCGGTGGTCTACGAGCCGATTCGCAA
GGAAGTTATCGACTATAAGATAGATCCGCTTGGCGGACATATCTTCTACGGCGTCGACCTCAAGAAATAG

Upstream 100 bases:

>100_bases
CGAGCCGGGCGGCGCCTTCCCGGAACAGACATAGTCACGATCAAGGACATTCGTCCCGGCCGCGCCCGTCCAAGGGCCGG
TCCATACTCTGGAGGACAGC

Downstream 100 bases:

>100_bases
CCGACAAAGCCGGCGGGGGAAGGCGATGCCTTCCCCCGTTTTTCATTGTGCGGCGCGGGGCGGACACTCGCTCCTTCTGC
GGTAGCCGACGGATTCCAAG

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MRKIVIGAASAVILAMAASGAQAKTLVYCSEGSPEGFNPAFYTTGTTFDATSKNIFDKLVLFKRGTTEIEPGLAESWEVS
PDGKTYTFHLRKGVTFHDSDIFKPTRQFNADDVIWSFERQLKKDHPYHAVSGGTYDYFEGMSMNTLLEKIEKVDDYTVVF
HLSRPEAPMLANLAMDFASIFSAEYADKMMKAGTPEVVDQKPIGTGPFMFRGYQKDAQIRYEANPTYWQGKAAIDRLVFV
ITPDASVRYAKLKAGECHVMPYPNPADLEAMKTDKAVNLMHQEGLNVGYLAYNVEKKPFDDVRVRKALNLAIDKKAIIDA
VYQGAGTAATNPIPPTIWSYNKAVKDDAFDPAAAKKLLAEAGVKDLKTTIWAMPVQRPYNPNARRMAEILQANWKAVGVD
AEITSYEWGEYLKRAKAGEHETALFGWTGDNGDPDNFLAVLLGCDAIPGNNYARWCDKSFENLIQKAKIATSQEERVKLY
EEAQVIFKEQAPWATIAHSVVYEPIRKEVIDYKIDPLGGHIFYGVDLKK

Sequences:

>Translated_529_residues
MRKIVIGAASAVILAMAASGAQAKTLVYCSEGSPEGFNPAFYTTGTTFDATSKNIFDKLVLFKRGTTEIEPGLAESWEVS
PDGKTYTFHLRKGVTFHDSDIFKPTRQFNADDVIWSFERQLKKDHPYHAVSGGTYDYFEGMSMNTLLEKIEKVDDYTVVF
HLSRPEAPMLANLAMDFASIFSAEYADKMMKAGTPEVVDQKPIGTGPFMFRGYQKDAQIRYEANPTYWQGKAAIDRLVFV
ITPDASVRYAKLKAGECHVMPYPNPADLEAMKTDKAVNLMHQEGLNVGYLAYNVEKKPFDDVRVRKALNLAIDKKAIIDA
VYQGAGTAATNPIPPTIWSYNKAVKDDAFDPAAAKKLLAEAGVKDLKTTIWAMPVQRPYNPNARRMAEILQANWKAVGVD
AEITSYEWGEYLKRAKAGEHETALFGWTGDNGDPDNFLAVLLGCDAIPGNNYARWCDKSFENLIQKAKIATSQEERVKLY
EEAQVIFKEQAPWATIAHSVVYEPIRKEVIDYKIDPLGGHIFYGVDLKK
>Mature_529_residues
MRKIVIGAASAVILAMAASGAQAKTLVYCSEGSPEGFNPAFYTTGTTFDATSKNIFDKLVLFKRGTTEIEPGLAESWEVS
PDGKTYTFHLRKGVTFHDSDIFKPTRQFNADDVIWSFERQLKKDHPYHAVSGGTYDYFEGMSMNTLLEKIEKVDDYTVVF
HLSRPEAPMLANLAMDFASIFSAEYADKMMKAGTPEVVDQKPIGTGPFMFRGYQKDAQIRYEANPTYWQGKAAIDRLVFV
ITPDASVRYAKLKAGECHVMPYPNPADLEAMKTDKAVNLMHQEGLNVGYLAYNVEKKPFDDVRVRKALNLAIDKKAIIDA
VYQGAGTAATNPIPPTIWSYNKAVKDDAFDPAAAKKLLAEAGVKDLKTTIWAMPVQRPYNPNARRMAEILQANWKAVGVD
AEITSYEWGEYLKRAKAGEHETALFGWTGDNGDPDNFLAVLLGCDAIPGNNYARWCDKSFENLIQKAKIATSQEERVKLY
EEAQVIFKEQAPWATIAHSVVYEPIRKEVIDYKIDPLGGHIFYGVDLKK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=521, Percent_Identity=63.531669865643, Blast_Score=696, Evalue=0.0,
Organism=Escherichia coli, GI1787551, Length=527, Percent_Identity=33.2068311195446, Blast_Score=334, Evalue=7e-93,
Organism=Escherichia coli, GI1787052, Length=537, Percent_Identity=25.8845437616387, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1787762, Length=528, Percent_Identity=25, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1789397, Length=473, Percent_Identity=26.215644820296, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1787495, Length=510, Percent_Identity=24.9019607843137, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1789887, Length=520, Percent_Identity=23.6538461538462, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87081878, Length=521, Percent_Identity=24.5681381957774, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59050; Mature: 59050

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIVIGAASAVILAMAASGAQAKTLVYCSEGSPEGFNPAFYTTGTTFDATSKNIFDKLV
CCEEEEEHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCHHHHHHHHH
LFKRGTTEIEPGLAESWEVSPDGKTYTFHLRKGVTFHDSDIFKPTRQFNADDVIWSFERQ
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEECCCCCCCCHHHCCCCHHHHHHHHH
LKKDHPYHAVSGGTYDYFEGMSMNTLLEKIEKVDDYTVVFHLSRPEAPMLANLAMDFASI
HHHCCCCEEECCCCHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHH
FSAEYADKMMKAGTPEVVDQKPIGTGPFMFRGYQKDAQIRYEANPTYWQGKAAIDRLVFV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCEECCHHHHCEEEEE
ITPDASVRYAKLKAGECHVMPYPNPADLEAMKTDKAVNLMHQEGLNVGYLAYNVEKKPFD
ECCCCCEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCH
DVRVRKALNLAIDKKAIIDAVYQGAGTAATNPIPPTIWSYNKAVKDDAFDPAAAKKLLAE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHCCCCCCHHHHHHHHHH
AGVKDLKTTIWAMPVQRPYNPNARRMAEILQANWKAVGVDAEITSYEWGEYLKRAKAGEH
HCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEECCCEECCCHHHHHHHHHCCCCC
ETALFGWTGDNGDPDNFLAVLLGCDAIPGNNYARWCDKSFENLIQKAKIATSQEERVKLY
CEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EEAQVIFKEQAPWATIAHSVVYEPIRKEVIDYKIDPLGGHIFYGVDLKK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEEECCCCCEEEEEEEECC
>Mature Secondary Structure
MRKIVIGAASAVILAMAASGAQAKTLVYCSEGSPEGFNPAFYTTGTTFDATSKNIFDKLV
CCEEEEEHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCHHHHHHHHH
LFKRGTTEIEPGLAESWEVSPDGKTYTFHLRKGVTFHDSDIFKPTRQFNADDVIWSFERQ
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEECCCCCCCCHHHCCCCHHHHHHHHH
LKKDHPYHAVSGGTYDYFEGMSMNTLLEKIEKVDDYTVVFHLSRPEAPMLANLAMDFASI
HHHCCCCEEECCCCHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHH
FSAEYADKMMKAGTPEVVDQKPIGTGPFMFRGYQKDAQIRYEANPTYWQGKAAIDRLVFV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCEECCHHHHCEEEEE
ITPDASVRYAKLKAGECHVMPYPNPADLEAMKTDKAVNLMHQEGLNVGYLAYNVEKKPFD
ECCCCCEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCH
DVRVRKALNLAIDKKAIIDAVYQGAGTAATNPIPPTIWSYNKAVKDDAFDPAAAKKLLAE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHCCCCCCHHHHHHHHHH
AGVKDLKTTIWAMPVQRPYNPNARRMAEILQANWKAVGVDAEITSYEWGEYLKRAKAGEH
HCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEECCCEECCCHHHHHHHHHCCCCC
ETALFGWTGDNGDPDNFLAVLLGCDAIPGNNYARWCDKSFENLIQKAKIATSQEERVKLY
CEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EEAQVIFKEQAPWATIAHSVVYEPIRKEVIDYKIDPLGGHIFYGVDLKK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEEECCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]