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The map label for this gene is pyc [H]

Identifier: 83593652

GI number: 83593652

Start: 2681989

End: 2685429

Strand: Direct

Name: pyc [H]

Synonym: Rru_A2317

Alternate gene names: 83593652

Gene position: 2681989-2685429 (Clockwise)

Preceding gene: 83593650

Following gene: 83593653

Centisome position: 61.61

GC content: 65.56

Gene sequence:

>3441_bases
ATGGGGCAAAAGATCAAGCGGCTGATGGTCGCCAATCGTTCGGAGATCGCGATCCGCGTTTTTCGGGCGGCGGCGGAACT
CGGGATCCGAACCGTCGCCCTCTATGCCGAAGAGGACCGGCTGTCGCTGCACCGTTTCAAGGCGGACGAGGCTTACCGCG
TGGGGGCCGGCAAAGGGCCGCTTCAGGCTTATCTGGCGATCGATGACATCATCGACATCGCCACGCGCGAAAAGATCGAC
GCCATCCATCCCGGATACGGTTTTTTGTCGGAAGACCCGGCCTTCGCCGAAGCCTGCGCCGCGGCGGGCATTCGGTTCAT
CGGCCCGACGCCCGAAACCCTGCGCCAACTCGGCAACAAGGTCGCGGCCCGCAATTTGGCCCGATCGCTCGGCGTGCCGG
TGATGCCGGCGACGGGTCCCCTGCCCACGGATCCGGGGGTGATCCACCGTCTCGCCAAGGATATCGGCTATCCGGTGATG
CTGAAGGCCTCCTGGGGCGGTGGCGGCCGGGGCATGCGCCCGATCGACAGCGAGGAGCACCTGCTTGACGCGGTCACCAC
ATCCCGGCGCGAGGCGGCGGCGGCCTTCGGAAAGGATGAGGTCTATCTTGAAAAGCTCGTCCGCGCCGCCCGCCATGTCG
AGGTGCAACTGCTCGGCGACAGCCATGGCACGCTTGTTCACCTGTTTGAACGCGACTGTTCCATCCAACGCCGCCATCAG
AAGGTCATCGAGCGCGCCCCCGCCCCCTATCTGGATAGCGAGACCCGGAGGCGGCTGACCGACGCGGCGTTAAAGATCGG
CCGCGCCACCGGCTATGTCGGGGCCGGAACCGTCGAGTTCCTGATGGACGTGGCGACCAACGACTTCTTCTTCATCGAGG
TCAATCCCCGCATTCAGGTCGAGCATACCGTGACCGAGGTCGTGACCGGCCTCGATCTGGTGAAAGCCCAGATCCGCATC
GCCGAGGGCGGGCATATCGGCCAAACCGCCGAAACGGGAATTCCGGCGCAAGAGGCGATTTGCCTCAATGGCCACGCCAT
GCAATGCCGGATCACCACGGAAGATCCCGAGCGTGGCTTCGTTCCCGACTACGGCCGGATCTCCGCCTATCGCGGCGCCT
CCGGCTTCGGCATCCGGGTGGATGGCGGAACGGCCTATTCGGGCGCCGTGGTCACACCGTTCTACGACGCCATGCTGGAA
AAGGTGACGGCCTGGGCCCCGACGCCCGATGAGGTCATCGCCCGGATGGAACGGGTTCTGCGGGAATACCGCATTCGCGG
CATCGCCACCAATCTGCCCTTCCTGGAAGCGATCTTGGCCCATCCCGACTTCCGGGCAACGCGCTACACCACGCGCTTCA
TCGACGAAACGCCGGCGTTGTTCAACAGCCCGCGACGCCGCGATCGCGCCACCAAGCTTCTGACCTATATCGCCGATATC
ACGGTCAATGGCCATCCGGAGATGGCCGGGCGGCCGCCCCGCGCCGTGGCGCGGATCCCCGAACCGCCCCGTTTGGGAAC
GACGCGGCGGGAGGGGACGAAACAAGGCCTCGATCGGCTGGGAGCGGACGGCTTCGCCCGCTGGATGCGCGCGCAGGATC
GGGTTCTCATCACCGATACCACCCTGCGCGACGCCCATCAGTCTCTGCTGGCCACCCGCTTGCGCAGTTACGACATCGTG
CGGGCGGCCGAGGCTTACGCCACCGGCTTGCCCGACTTGCTGTCGCTGGAATGCTGGGGCGGCGCCACCTTCGATGTCGC
CCTGCGCTTCCTTTCCGAAGATCCCTGGGAACGGCTGGCGGCGATCCGGGAGCGCGTGCCCAATATCCTGCTTCAGATGC
TGCTGCGCGGCGCGAATGGCGTGGGCTACACGAATTATCCCGATAACGTCGTCCGCTTTTTCGTCGCCCGGGCGGCGGAG
GGGGGGATCGATCTTTTTCGTATCTTCGACTGCCTCAACTGGATCGACAACATGCGCGTCGCCATCGACGCCGTGTGCGA
GGCCGGCAAGATCGCCGAAGGCGCCATCTGCTATACCGGCGACATCCTCGACCCCGACCGGGCCAAATATTCGCTGCGCT
ATTACGTCGATCTCGCCCAGCAGCTCGATGCCGCCGGCTGCCATGTGATCGCCATCAAGGATATGGCCGGGCTTTTGAGC
CCGAAAGCGGCGAAAGTCCTGGTAAGGGTTCTGCGCAACGTCACCGACCGCCCCCTTCACCTCCATACCCACGACACCTC
GGGCACCGCCGCCGCGACCCTCATCGCCGCCATCGACGCCGGGGTCGACGCCGTCGATCTGGCCATGGACGCCCTGTCGG
GCACCACCTCCCAACCCTGTCTCGGCTCCGTGGTCGCGGCGATCGGCAAAAGCGACCGCGACAGCGGCCTCGATGCCGAG
GCGATCCGTCGGATGAGCCTGTATTGGGAAGACGTCCGCGCCCTTTATGGCGCCTTTGAAAGCGACCTGCGCGCCGGAGC
CTCGGAAGTCTATCTCCACGAGATGCCGGGCGGCCAGTTCACCAATCTGAAAGAGCAGGCCCGGGCGCTGGGCTTGGCCA
ACCGCTGGCACGACGTGGCGGCGGCTTACCGACAGGCCAATGATCTGTTTGGCGATATCGTCAAGGTCACGCCCTCGTCC
AAGGTCGTTGGCGACATGGCGCTGATGATGGTGTCGCAGGGGCTTACTCCCGAAGACGTGCTCAATCCCGACCGCGACAT
CGCCTTTCCGGCCTCGGTCGTCGACATGCTCAAGGGAGACCTGGGGCAGCCTTATGGCGGCTGGCCCGAAGCCCTGCGCA
AAAAGGTCCTCAAAGGCCAAGCCCCCTTGACCGTCCGCCCCGGCGCCTTGCTGGGAACGGCCGATCTGGGGGCCCTGCGC
GCCAAAACCGCGGCCGAGATCGGCCGTCCGGTCGATAACCGCGATCTCGCCTCGGCGCTGATGTACCCCAAGGTCTTCGC
CGATTTCGCCCGCGCCACCGAGACCTGGGGCCCGGTGGCCGTCCTGCCCACGCCCACCTTCTTTGGCGGCATGAAAGTCG
GCGAAGAAATCGTCGTCGAGATCGAACCGGGCAAATCCCTGATCATCGTGCTTCAGGCGATTGGCGCCGCCGAGCCGGAC
GGCAAGGTCAAGCTGTTCTTCGAGTTGAACGGCCAGCCCCGGGTGATCCGCGTCGCCGACCGCAGCCGGGTGGCCGCTCC
CCCCCGCCCCAAAGCCATCGAGGGCGACGATCGGCAGGTCGCCGCGCCAATGGCCGGGGCCGTCTCCTCGATCCTCGCCC
ACAAGGGACAGGCCGTCGCGGCGGGCGATCCCCTGCTGACCCTGGAGGCGATGAAGATGGAAACGACCCTTCACGCCCCC
CGCGACGGAATCGTCGCCGATCTGCTGGTCCAGGTTCAAGAAACCGTGGAAAGCAAAGACCTTCTGCTTCTGCTTCAGTA
A

Upstream 100 bases:

>100_bases
GCAAAGCCTCCGCAAACCTTTGCACGTTCAGCCATTTCCCCTGCCCGGGGCGCCGCCGATAGTGCCGGTCGGATTGTTCA
AACTGAGGCGGCGGGAAAAA

Downstream 100 bases:

>100_bases
TTCCCCGGCAAAAAACCGGAACTTCGCAATCTTCGCAGATTCGCAGAACGGCCTCTTCAAGACTTCACGGTTTCAGCCCT
GTCCCACGCATCGCCCCTTG

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1146; Mature: 1145

Protein sequence:

>1146_residues
MGQKIKRLMVANRSEIAIRVFRAAAELGIRTVALYAEEDRLSLHRFKADEAYRVGAGKGPLQAYLAIDDIIDIATREKID
AIHPGYGFLSEDPAFAEACAAAGIRFIGPTPETLRQLGNKVAARNLARSLGVPVMPATGPLPTDPGVIHRLAKDIGYPVM
LKASWGGGGRGMRPIDSEEHLLDAVTTSRREAAAAFGKDEVYLEKLVRAARHVEVQLLGDSHGTLVHLFERDCSIQRRHQ
KVIERAPAPYLDSETRRRLTDAALKIGRATGYVGAGTVEFLMDVATNDFFFIEVNPRIQVEHTVTEVVTGLDLVKAQIRI
AEGGHIGQTAETGIPAQEAICLNGHAMQCRITTEDPERGFVPDYGRISAYRGASGFGIRVDGGTAYSGAVVTPFYDAMLE
KVTAWAPTPDEVIARMERVLREYRIRGIATNLPFLEAILAHPDFRATRYTTRFIDETPALFNSPRRRDRATKLLTYIADI
TVNGHPEMAGRPPRAVARIPEPPRLGTTRREGTKQGLDRLGADGFARWMRAQDRVLITDTTLRDAHQSLLATRLRSYDIV
RAAEAYATGLPDLLSLECWGGATFDVALRFLSEDPWERLAAIRERVPNILLQMLLRGANGVGYTNYPDNVVRFFVARAAE
GGIDLFRIFDCLNWIDNMRVAIDAVCEAGKIAEGAICYTGDILDPDRAKYSLRYYVDLAQQLDAAGCHVIAIKDMAGLLS
PKAAKVLVRVLRNVTDRPLHLHTHDTSGTAAATLIAAIDAGVDAVDLAMDALSGTTSQPCLGSVVAAIGKSDRDSGLDAE
AIRRMSLYWEDVRALYGAFESDLRAGASEVYLHEMPGGQFTNLKEQARALGLANRWHDVAAAYRQANDLFGDIVKVTPSS
KVVGDMALMMVSQGLTPEDVLNPDRDIAFPASVVDMLKGDLGQPYGGWPEALRKKVLKGQAPLTVRPGALLGTADLGALR
AKTAAEIGRPVDNRDLASALMYPKVFADFARATETWGPVAVLPTPTFFGGMKVGEEIVVEIEPGKSLIIVLQAIGAAEPD
GKVKLFFELNGQPRVIRVADRSRVAAPPRPKAIEGDDRQVAAPMAGAVSSILAHKGQAVAAGDPLLTLEAMKMETTLHAP
RDGIVADLLVQVQETVESKDLLLLLQ

Sequences:

>Translated_1146_residues
MGQKIKRLMVANRSEIAIRVFRAAAELGIRTVALYAEEDRLSLHRFKADEAYRVGAGKGPLQAYLAIDDIIDIATREKID
AIHPGYGFLSEDPAFAEACAAAGIRFIGPTPETLRQLGNKVAARNLARSLGVPVMPATGPLPTDPGVIHRLAKDIGYPVM
LKASWGGGGRGMRPIDSEEHLLDAVTTSRREAAAAFGKDEVYLEKLVRAARHVEVQLLGDSHGTLVHLFERDCSIQRRHQ
KVIERAPAPYLDSETRRRLTDAALKIGRATGYVGAGTVEFLMDVATNDFFFIEVNPRIQVEHTVTEVVTGLDLVKAQIRI
AEGGHIGQTAETGIPAQEAICLNGHAMQCRITTEDPERGFVPDYGRISAYRGASGFGIRVDGGTAYSGAVVTPFYDAMLE
KVTAWAPTPDEVIARMERVLREYRIRGIATNLPFLEAILAHPDFRATRYTTRFIDETPALFNSPRRRDRATKLLTYIADI
TVNGHPEMAGRPPRAVARIPEPPRLGTTRREGTKQGLDRLGADGFARWMRAQDRVLITDTTLRDAHQSLLATRLRSYDIV
RAAEAYATGLPDLLSLECWGGATFDVALRFLSEDPWERLAAIRERVPNILLQMLLRGANGVGYTNYPDNVVRFFVARAAE
GGIDLFRIFDCLNWIDNMRVAIDAVCEAGKIAEGAICYTGDILDPDRAKYSLRYYVDLAQQLDAAGCHVIAIKDMAGLLS
PKAAKVLVRVLRNVTDRPLHLHTHDTSGTAAATLIAAIDAGVDAVDLAMDALSGTTSQPCLGSVVAAIGKSDRDSGLDAE
AIRRMSLYWEDVRALYGAFESDLRAGASEVYLHEMPGGQFTNLKEQARALGLANRWHDVAAAYRQANDLFGDIVKVTPSS
KVVGDMALMMVSQGLTPEDVLNPDRDIAFPASVVDMLKGDLGQPYGGWPEALRKKVLKGQAPLTVRPGALLGTADLGALR
AKTAAEIGRPVDNRDLASALMYPKVFADFARATETWGPVAVLPTPTFFGGMKVGEEIVVEIEPGKSLIIVLQAIGAAEPD
GKVKLFFELNGQPRVIRVADRSRVAAPPRPKAIEGDDRQVAAPMAGAVSSILAHKGQAVAAGDPLLTLEAMKMETTLHAP
RDGIVADLLVQVQETVESKDLLLLLQ
>Mature_1145_residues
GQKIKRLMVANRSEIAIRVFRAAAELGIRTVALYAEEDRLSLHRFKADEAYRVGAGKGPLQAYLAIDDIIDIATREKIDA
IHPGYGFLSEDPAFAEACAAAGIRFIGPTPETLRQLGNKVAARNLARSLGVPVMPATGPLPTDPGVIHRLAKDIGYPVML
KASWGGGGRGMRPIDSEEHLLDAVTTSRREAAAAFGKDEVYLEKLVRAARHVEVQLLGDSHGTLVHLFERDCSIQRRHQK
VIERAPAPYLDSETRRRLTDAALKIGRATGYVGAGTVEFLMDVATNDFFFIEVNPRIQVEHTVTEVVTGLDLVKAQIRIA
EGGHIGQTAETGIPAQEAICLNGHAMQCRITTEDPERGFVPDYGRISAYRGASGFGIRVDGGTAYSGAVVTPFYDAMLEK
VTAWAPTPDEVIARMERVLREYRIRGIATNLPFLEAILAHPDFRATRYTTRFIDETPALFNSPRRRDRATKLLTYIADIT
VNGHPEMAGRPPRAVARIPEPPRLGTTRREGTKQGLDRLGADGFARWMRAQDRVLITDTTLRDAHQSLLATRLRSYDIVR
AAEAYATGLPDLLSLECWGGATFDVALRFLSEDPWERLAAIRERVPNILLQMLLRGANGVGYTNYPDNVVRFFVARAAEG
GIDLFRIFDCLNWIDNMRVAIDAVCEAGKIAEGAICYTGDILDPDRAKYSLRYYVDLAQQLDAAGCHVIAIKDMAGLLSP
KAAKVLVRVLRNVTDRPLHLHTHDTSGTAAATLIAAIDAGVDAVDLAMDALSGTTSQPCLGSVVAAIGKSDRDSGLDAEA
IRRMSLYWEDVRALYGAFESDLRAGASEVYLHEMPGGQFTNLKEQARALGLANRWHDVAAAYRQANDLFGDIVKVTPSSK
VVGDMALMMVSQGLTPEDVLNPDRDIAFPASVVDMLKGDLGQPYGGWPEALRKKVLKGQAPLTVRPGALLGTADLGALRA
KTAAEIGRPVDNRDLASALMYPKVFADFARATETWGPVAVLPTPTFFGGMKVGEEIVVEIEPGKSLIIVLQAIGAAEPDG
KVKLFFELNGQPRVIRVADRSRVAAPPRPKAIEGDDRQVAAPMAGAVSSILAHKGQAVAAGDPLLTLEAMKMETTLHAPR
DGIVADLLVQVQETVESKDLLLLLQ

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1156, Percent_Identity=48.4429065743945, Blast_Score=1042, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1156, Percent_Identity=48.4429065743945, Blast_Score=1042, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1156, Percent_Identity=48.4429065743945, Blast_Score=1042, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=457, Percent_Identity=44.8577680525164, Blast_Score=388, Evalue=1e-107,
Organism=Homo sapiens, GI189095269, Length=452, Percent_Identity=41.1504424778761, Blast_Score=338, Evalue=1e-92,
Organism=Homo sapiens, GI65506442, Length=452, Percent_Identity=41.1504424778761, Blast_Score=338, Evalue=2e-92,
Organism=Homo sapiens, GI295821183, Length=452, Percent_Identity=41.1504424778761, Blast_Score=338, Evalue=2e-92,
Organism=Homo sapiens, GI38679960, Length=503, Percent_Identity=30.0198807157058, Blast_Score=230, Evalue=5e-60,
Organism=Homo sapiens, GI38679977, Length=503, Percent_Identity=30.0198807157058, Blast_Score=230, Evalue=6e-60,
Organism=Homo sapiens, GI38679967, Length=503, Percent_Identity=30.0198807157058, Blast_Score=230, Evalue=6e-60,
Organism=Homo sapiens, GI38679974, Length=503, Percent_Identity=30.0198807157058, Blast_Score=230, Evalue=6e-60,
Organism=Homo sapiens, GI38679971, Length=503, Percent_Identity=29.8210735586481, Blast_Score=230, Evalue=8e-60,
Organism=Homo sapiens, GI134142062, Length=504, Percent_Identity=30.5555555555556, Blast_Score=222, Evalue=2e-57,
Organism=Escherichia coli, GI1789654, Length=457, Percent_Identity=43.3260393873085, Blast_Score=341, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17562816, Length=1131, Percent_Identity=48.2758620689655, Blast_Score=1036, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=461, Percent_Identity=45.3362255965293, Blast_Score=369, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17567343, Length=473, Percent_Identity=38.9006342494715, Blast_Score=326, Evalue=4e-89,
Organism=Caenorhabditis elegans, GI133931226, Length=501, Percent_Identity=31.1377245508982, Blast_Score=219, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI71997163, Length=522, Percent_Identity=27.7777777777778, Blast_Score=196, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI71997168, Length=522, Percent_Identity=27.7777777777778, Blast_Score=196, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1164, Percent_Identity=46.8213058419244, Blast_Score=1041, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1164, Percent_Identity=47.3367697594502, Blast_Score=1025, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=448, Percent_Identity=39.0625, Blast_Score=317, Evalue=9e-87,
Organism=Saccharomyces cerevisiae, GI6323863, Length=450, Percent_Identity=34.4444444444444, Blast_Score=245, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6324343, Length=517, Percent_Identity=32.1083172147002, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24652212, Length=1152, Percent_Identity=47.9166666666667, Blast_Score=1055, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1152, Percent_Identity=47.9166666666667, Blast_Score=1055, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1152, Percent_Identity=47.9166666666667, Blast_Score=1055, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1152, Percent_Identity=47.9166666666667, Blast_Score=1055, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1152, Percent_Identity=47.9166666666667, Blast_Score=1055, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1173, Percent_Identity=47.1440750213129, Blast_Score=1054, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1173, Percent_Identity=47.1440750213129, Blast_Score=1054, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1173, Percent_Identity=47.1440750213129, Blast_Score=1054, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1173, Percent_Identity=47.1440750213129, Blast_Score=1054, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1173, Percent_Identity=47.1440750213129, Blast_Score=1054, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=472, Percent_Identity=41.7372881355932, Blast_Score=360, Evalue=3e-99,
Organism=Drosophila melanogaster, GI24651759, Length=434, Percent_Identity=41.2442396313364, Blast_Score=322, Evalue=1e-87,
Organism=Drosophila melanogaster, GI161076409, Length=500, Percent_Identity=30.4, Blast_Score=220, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24586458, Length=500, Percent_Identity=30.4, Blast_Score=220, Evalue=5e-57,
Organism=Drosophila melanogaster, GI161076407, Length=500, Percent_Identity=30.4, Blast_Score=220, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24586460, Length=500, Percent_Identity=30.4, Blast_Score=220, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 124521; Mature: 124390

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50975 ATP_GRASP ; PS00165 DEHYDRATASE_SER_THR ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQKIKRLMVANRSEIAIRVFRAAAELGIRTVALYAEEDRLSLHRFKADEAYRVGAGKGP
CCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCCCEEECCCCCC
LQAYLAIDDIIDIATREKIDAIHPGYGFLSEDPAFAEACAAAGIRFIGPTPETLRQLGNK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHH
VAARNLARSLGVPVMPATGPLPTDPGVIHRLAKDIGYPVMLKASWGGGGRGMRPIDSEEH
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHH
LLDAVTTSRREAAAAFGKDEVYLEKLVRAARHVEVQLLGDSHGTLVHLFERDCSIQRRHQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEEECCCCCCEEEEEHHCCHHHHHHH
KVIERAPAPYLDSETRRRLTDAALKIGRATGYVGAGTVEFLMDVATNDFFFIEVNPRIQV
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCEEE
EHTVTEVVTGLDLVKAQIRIAEGGHIGQTAETGIPAQEAICLNGHAMQCRITTEDPERGF
HHHHHHHHHHHHHHHHHEEEECCCCCCCCHHCCCCHHHEEEECCCEEEEEEECCCCCCCC
VPDYGRISAYRGASGFGIRVDGGTAYSGAVVTPFYDAMLEKVTAWAPTPDEVIARMERVL
CCCCCCCEEECCCCCCEEEECCCCCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
REYRIRGIATNLPFLEAILAHPDFRATRYTTRFIDETPALFNSPRRRDRATKLLTYIADI
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHE
TVNGHPEMAGRPPRAVARIPEPPRLGTTRREGTKQGLDRLGADGFARWMRAQDRVLITDT
EECCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEC
TLRDAHQSLLATRLRSYDIVRAAEAYATGLPDLLSLECWGGATFDVALRFLSEDPWERLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHHHHHCCCHHHHHH
AIRERVPNILLQMLLRGANGVGYTNYPDNVVRFFVARAAEGGIDLFRIFDCLNWIDNMRV
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AIDAVCEAGKIAEGAICYTGDILDPDRAKYSLRYYVDLAQQLDAAGCHVIAIKDMAGLLS
HHHHHHCCCCCCCCEEEEECCCCCCCCHHEEHHHHHHHHHHHCCCCEEEEEEHHHHHHCC
PKAAKVLVRVLRNVTDRPLHLHTHDTSGTAAATLIAAIDAGVDAVDLAMDALSGTTSQPC
CHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCH
LGSVVAAIGKSDRDSGLDAEAIRRMSLYWEDVRALYGAFESDLRAGASEVYLHEMPGGQF
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
TNLKEQARALGLANRWHDVAAAYRQANDLFGDIVKVTPSSKVVGDMALMMVSQGLTPEDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHH
LNPDRDIAFPASVVDMLKGDLGQPYGGWPEALRKKVLKGQAPLTVRPGALLGTADLGALR
CCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCEECCCCHHHHH
AKTAAEIGRPVDNRDLASALMYPKVFADFARATETWGPVAVLPTPTFFGGMKVGEEIVVE
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHCCCCCCCEEEEE
IEPGKSLIIVLQAIGAAEPDGKVKLFFELNGQPRVIRVADRSRVAAPPRPKAIEGDDRQV
ECCCCEEEEEEEHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEE
AAPMAGAVSSILAHKGQAVAAGDPLLTLEAMKMETTLHAPRDGIVADLLVQVQETVESKD
HHHHHHHHHHHHHCCCCEEECCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
LLLLLQ
EEEEEC
>Mature Secondary Structure 
GQKIKRLMVANRSEIAIRVFRAAAELGIRTVALYAEEDRLSLHRFKADEAYRVGAGKGP
CHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCCCEEECCCCCC
LQAYLAIDDIIDIATREKIDAIHPGYGFLSEDPAFAEACAAAGIRFIGPTPETLRQLGNK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHH
VAARNLARSLGVPVMPATGPLPTDPGVIHRLAKDIGYPVMLKASWGGGGRGMRPIDSEEH
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHH
LLDAVTTSRREAAAAFGKDEVYLEKLVRAARHVEVQLLGDSHGTLVHLFERDCSIQRRHQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEEECCCCCCEEEEEHHCCHHHHHHH
KVIERAPAPYLDSETRRRLTDAALKIGRATGYVGAGTVEFLMDVATNDFFFIEVNPRIQV
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCEEE
EHTVTEVVTGLDLVKAQIRIAEGGHIGQTAETGIPAQEAICLNGHAMQCRITTEDPERGF
HHHHHHHHHHHHHHHHHEEEECCCCCCCCHHCCCCHHHEEEECCCEEEEEEECCCCCCCC
VPDYGRISAYRGASGFGIRVDGGTAYSGAVVTPFYDAMLEKVTAWAPTPDEVIARMERVL
CCCCCCCEEECCCCCCEEEECCCCCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
REYRIRGIATNLPFLEAILAHPDFRATRYTTRFIDETPALFNSPRRRDRATKLLTYIADI
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHE
TVNGHPEMAGRPPRAVARIPEPPRLGTTRREGTKQGLDRLGADGFARWMRAQDRVLITDT
EECCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEC
TLRDAHQSLLATRLRSYDIVRAAEAYATGLPDLLSLECWGGATFDVALRFLSEDPWERLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHHHHHCCCHHHHHH
AIRERVPNILLQMLLRGANGVGYTNYPDNVVRFFVARAAEGGIDLFRIFDCLNWIDNMRV
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AIDAVCEAGKIAEGAICYTGDILDPDRAKYSLRYYVDLAQQLDAAGCHVIAIKDMAGLLS
HHHHHHCCCCCCCCEEEEECCCCCCCCHHEEHHHHHHHHHHHCCCCEEEEEEHHHHHHCC
PKAAKVLVRVLRNVTDRPLHLHTHDTSGTAAATLIAAIDAGVDAVDLAMDALSGTTSQPC
CHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCH
LGSVVAAIGKSDRDSGLDAEAIRRMSLYWEDVRALYGAFESDLRAGASEVYLHEMPGGQF
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
TNLKEQARALGLANRWHDVAAAYRQANDLFGDIVKVTPSSKVVGDMALMMVSQGLTPEDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHH
LNPDRDIAFPASVVDMLKGDLGQPYGGWPEALRKKVLKGQAPLTVRPGALLGTADLGALR
CCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCEECCCCHHHHH
AKTAAEIGRPVDNRDLASALMYPKVFADFARATETWGPVAVLPTPTFFGGMKVGEEIVVE
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHCCCCCCCEEEEE
IEPGKSLIIVLQAIGAAEPDGKVKLFFELNGQPRVIRVADRSRVAAPPRPKAIEGDDRQV
ECCCCEEEEEEEHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEE
AAPMAGAVSSILAHKGQAVAAGDPLLTLEAMKMETTLHAPRDGIVADLLVQVQETVESKD
HHHHHHHHHHHHHCCCCEEECCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
LLLLLQ
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]